| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diego Centonze, Natalia Battista, Silvia Rossi, Nicola B Mercuri, Alessandro Finazzi-Agrò, Giorgio Bernardi, Paolo Calabresi, Mauro Maccarron. A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic Transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 8. 2004-09-08. PMID:15100701. |
in the present study, we have addressed the interaction between cocaine and endocannabinoid system by means of neurochemical and neurophysiological experiments in rat brain slices. |
2004-09-08 |
2023-08-12 |
rat |
| Diego Centonze, Natalia Battista, Silvia Rossi, Nicola B Mercuri, Alessandro Finazzi-Agrò, Giorgio Bernardi, Paolo Calabresi, Mauro Maccarron. A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic Transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 8. 2004-09-08. PMID:15100701. |
using gas chromatography-electron impact mass spectrometry, we have found that cocaine increased the levels of the endocannabinoid anandamide in the striatum, a brain area primarily involved in the compulsive drug-seeking and drug-taking behaviors typical of addiction. |
2004-09-08 |
2023-08-12 |
rat |
| Diego Centonze, Natalia Battista, Silvia Rossi, Nicola B Mercuri, Alessandro Finazzi-Agrò, Giorgio Bernardi, Paolo Calabresi, Mauro Maccarron. A critical interaction between dopamine D2 receptors and endocannabinoids mediates the effects of cocaine on striatal gabaergic Transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 8. 2004-09-08. PMID:15100701. |
by means of electrophysiological recordings from single striatal neurons, we have then observed that the ability of cocaine to inhibit, via d2-like receptors, gaba transmission was partially prevented following blockade of cannabinoid receptors, suggesting that endocannabinoids may act as downstream effectors in the action of cocaine in the striatum. |
2004-09-08 |
2023-08-12 |
rat |
| Olaf H Drumme. Postmortem toxicology of drugs of abuse. Forensic science international. vol 142. issue 2-3. 2004-09-02. PMID:15172074. |
this article reviews particular toxicological issues associated with the more common drugs of abuse such as the amphetamines, cannabinoids, cocaine, opioids and the benzodiazepines. |
2004-09-02 |
2023-08-12 |
Not clear |
| Hai-Ying M Cheng, Steven R Laviolette, Derek van der Kooy, Josef M Penninge. DREAM ablation selectively alters THC place aversion and analgesia but leaves intact the motivational and analgesic effects of morphine. The European journal of neuroscience. vol 19. issue 11. 2004-08-02. PMID:15182311. |
in the present study, we evaluated the motivational effects of opioids (morphine), cannabinoids [delta(9)-tetrahydrocannabinol (thc)] and cocaine in mice lacking the dream gene (dream(-/-)). |
2004-08-02 |
2023-08-12 |
mouse |
| Lars Kroener, Frank Musshoff, Burkhard Made. Evaluation of immunochemical drug screenings of whole blood samples. A retrospective optimization of cutoff levels after confirmation-analysis on GC-MS and HPLC-DAD. Journal of analytical toxicology. vol 27. issue 4. 2004-03-08. PMID:12820742. |
for the adx assay, specificities of 54% (cannabinoids) to 97% (cocaine and metabolite) and sensitivities of about 67% (amphetamine class) to 94% (opiates) were found. |
2004-03-08 |
2023-08-12 |
Not clear |
| H Kupferschmid. [Acute drug poisoning]. Therapeutische Umschau. Revue therapeutique. vol 60. issue 6. 2004-01-05. PMID:12848070. |
compounds of major importance are cannabinoids, opiates, cocaine, amphetamines, ecstasy, hallucinogens, phencyclidine, gammahydroxybutyrate, volatile nitrites, solvents, and nitrous oxide. |
2004-01-05 |
2023-08-12 |
Not clear |
| Albert D Fraser, Jiri Zamecni. Impact of lowering the screening and confirmation cutoff values for urine drug testing based on dilution indicators. Therapeutic drug monitoring. vol 25. issue 6. 2004-01-05. PMID:14639059. |
the drugs most often confirmed in dilute urine specimens from community settings in 2000-2002 were cannabinoids (annual positive rate ranged from 10.3 to 12.5%) and cocaine metabolite (ranged from 6.6 to 10.3%). |
2004-01-05 |
2023-08-12 |
Not clear |
| Elisabeth Vinner, Jean Vignau, Denise Thibault, Xavier Codaccioni, Claudie Brassart, Luc Humbert, Michel Lhermitt. Neonatal hair analysis contribution to establishing a gestational drug exposure profile and predicting a withdrawal syndrome. Therapeutic drug monitoring. vol 25. issue 4. 2003-12-15. PMID:12883224. |
cannabinoids, opiates, cocaine (and its metabolites), and methadone in particular were determined in the various matrices collected in 17 mother/neonate pairs. |
2003-12-15 |
2023-08-12 |
Not clear |
| Taco J De Vries, Judith R Homberg, Rob Binnekade, Halfdan Raasø, Anton N M Schoffelmee. Cannabinoid modulation of the reinforcing and motivational properties of heroin and heroin-associated cues in rats. Psychopharmacology. vol 168. issue 1-2. 2003-11-18. PMID:12669182. |
recently, we provided evidence for a cannabinoid mechanism in relapse to cocaine seeking in rats. |
2003-11-18 |
2023-08-12 |
rat |
| P Mura, P Kintz, B Ludes, J M Gaulier, P Marquet, S Martin-Dupont, F Vincent, A Kaddour, J P Goullé, J Nouveau, M Moulsma, S Tilhet-Coartet, O Pourra. Comparison of the prevalence of alcohol, cannabis and other drugs between 900 injured drivers and 900 control subjects: results of a French collaborative study. Forensic science international. vol 133. issue 1-2. 2003-07-29. PMID:12742692. |
a collaborative case-control study was conducted in france in order to determine the prevalence of alcohol, cannabinoids, opiates, cocaine metabolites, amphetamines and therapeutic psychoactive drugs in blood samples from drivers injured in road accidents and to compare these values with those of a control population. |
2003-07-29 |
2023-08-12 |
human |
| Frank Musshoff, Dirk W Lachenmeier, Burkhard Made. Methadone substitution: medicolegal problems in Germany. Forensic science international. vol 133. issue 1-2. 2003-07-29. PMID:12742698. |
in most of the cases, up to five additional drugs were also being taken: benzodiazepines (61%), ethanol (40%), morphine (39%), cannabinoids (35%), cocaine (28%), anti-depressants (3%), and amphetamines (2%). |
2003-07-29 |
2023-08-12 |
Not clear |
| Carmen Jurado, Hans Sach. Proficiency test for the analysis of hair for drugs of abuse, organized by the Society of Hair Testing. Forensic science international. vol 133. issue 1-2. 2003-07-29. PMID:12742707. |
participants were requested to analyze the samples following the standard procedure used routinely in their laboratories.the compounds present in the samples included opiates, cocaine and metabolite, cannabinoids and amphetamines. |
2003-07-29 |
2023-08-12 |
human |
| Carmen Jurado, Hans Sach. Proficiency test for the analysis of hair for drugs of abuse, organized by the Society of Hair Testing. Forensic science international. vol 133. issue 1-2. 2003-07-29. PMID:12742707. |
all the laboratories analyzed opiates, cocaine and benzoylecgonine (be); only 10 analyzed amphetamines, and 9 cannabinoids. |
2003-07-29 |
2023-08-12 |
human |
| Styliani Vlachou, George G Nomikos, George Panagi. WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation. Behavioural brain research. vol 141. issue 2. 2003-07-17. PMID:12742258. |
taken together these findings suggest that cannabinoids may interfere with brain-reward systems responsible for the expression of acute reinforcing properties of drugs of abuse, such as cocaine, and provide evidence that the cannabinoid system could be an interesting drug discovery and development target for the treatment of drug addiction. |
2003-07-17 |
2023-08-12 |
rat |
| G Gioino, C Hansen, A Pacchioni, F Rocca, S Molina Barrios, E Brocca, L M Cancel. Use of high-performance liquid chromatography with diode-array detection after a primary drug screening in patients admitted to the emergency department. Therapeutic drug monitoring. vol 25. issue 1. 2003-07-09. PMID:12548152. |
the rate of positive screens was 34.0% with the following rate distribution: 12.0% alcohol, 13.6% nonsteroid antiinflammatory drugs (nsaids), 2.0% anticonvulsants, 0.8% barbiturates, 0.4% narcotics, 0.4% antidepressants, 2.8% cocaine, and 2.0% cannabinoids. |
2003-07-09 |
2023-08-12 |
Not clear |
| G Gioino, C Hansen, A Pacchioni, F Rocca, S Molina Barrios, E Brocca, L M Cancel. Use of high-performance liquid chromatography with diode-array detection after a primary drug screening in patients admitted to the emergency department. Therapeutic drug monitoring. vol 25. issue 1. 2003-07-09. PMID:12548152. |
psychoactive drugs (alcohol, cocaine, and cannabinoids) were detected in 43.9% of the patients admitted for traffic accidents, namely 35.71% alcohol, 2.38% alcohol-cocaine, 2.38% alcohol-cannabinoids, 2.38% cocaine-cannabinoids, and 2.38% alcohol-cocaine-cannabinoids. |
2003-07-09 |
2023-08-12 |
Not clear |
| Javier Padilla, Ma Cristina Eguíalis, Francisco Mendoza, Victor A Santos, Patricia Ojed. Monoclonal antibody urine assay for amphetamines, cocaine and cannabinoids: a pilot study of Mexican athletes. Proceedings of the Western Pharmacology Society. vol 45. 2003-05-13. PMID:12434578. |
monoclonal antibody urine assay for amphetamines, cocaine and cannabinoids: a pilot study of mexican athletes. |
2003-05-13 |
2023-08-12 |
Not clear |
| James R Gill, Lara B Goldfeder, Marina Staji. The happy land homicides: 87 deaths due to smoke inhalation. Journal of forensic sciences. vol 48. issue 1. 2003-03-18. PMID:12570219. |
cocaine or cannabinoid use was identified in 9% of the decedents. |
2003-03-18 |
2023-08-12 |
Not clear |
| Sara González, Maria Grazia Cascio, Javier Fernández-Ruiz, Filomena Fezza, Vincenzo Di Marzo, José A Ramo. Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393235. |
changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. |
2003-01-24 |
2023-08-12 |
rat |