| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G L Gessa, M Melis, A L Muntoni, M Dian. Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors. European journal of pharmacology. vol 341. issue 1. 1998-04-29. PMID:9489854. |
these findings support the contention that cannabinoids regulate mesolimbic dopamine transmission and may help to explain the addictive properties of marijuana. |
1998-04-29 |
2023-08-12 |
rat |
| K R Müller-Vahl, H Kolbe, R Dengle. [Gilles de la Tourette syndrome. Effect of nicotine, alcohol and marihuana on clinical symptoms]. Der Nervenarzt. vol 68. issue 12. 1998-04-01. PMID:9465342. |
we suggest that marijuana influences an assumed interaction between cannabinoid and dopamine receptors and, by this, influences the dopaminergic processes in basal ganglia and motor activity. |
1998-04-01 |
2023-08-12 |
Not clear |
| A Linacre, J Thorp. Detection and identification of cannabis by DNA. Forensic science international. vol 91. issue 1. 1998-04-01. PMID:9493346. |
current methods of cannabis identification involve the use of techniques such as hplc and gc to identify cannabinoids. |
1998-04-01 |
2023-08-12 |
Not clear |
| J M Kirk, P Doty, H De Wi. Effects of expectancies on subjective responses to oral delta9-tetrahydrocannabinol. Pharmacology, biochemistry, and behavior. vol 59. issue 2. 1998-03-31. PMID:9476972. |
thirty-five regular marijuana users were assigned to one of two groups: one group was told that they may receive a cannabinoid or placebo and a second group was told that they may receive a drug from one of several classes of drugs (e.g., stimulant, sedative, antiemetic) or placebo. |
1998-03-31 |
2023-08-12 |
human |
| E Schlicker, J Timm, J Zentner, M Göther. Cannabinoid CB1 receptor-mediated inhibition of noradrenaline release in the human and guinea-pig hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 356. issue 5. 1998-02-19. PMID:9402037. |
in conclusion, cannabinoid receptors of the cb1 subtype occur in the human hippocampus, where they may contribute to the psychotropic effects of cannabis, and in the guinea-pig hippocampus, cerebellum, cerebral cortex and hypothalamus. |
1998-02-19 |
2023-08-12 |
mouse |
| S J Gatley, R Lan, N D Volkow, N Pappas, P King, C T Wong, A N Gifford, B Pyatt, S L Dewey, A Makriyanni. Imaging the brain marijuana receptor: development of a radioligand that binds to cannabinoid CB1 receptors in vivo. Journal of neurochemistry. vol 70. issue 1. 1998-02-02. PMID:9422389. |
imaging the brain marijuana receptor: development of a radioligand that binds to cannabinoid cb1 receptors in vivo. |
1998-02-02 |
2023-08-12 |
mouse |
| S J Gatley, R Lan, N D Volkow, N Pappas, P King, C T Wong, A N Gifford, B Pyatt, S L Dewey, A Makriyanni. Imaging the brain marijuana receptor: development of a radioligand that binds to cannabinoid CB1 receptors in vivo. Journal of neurochemistry. vol 70. issue 1. 1998-02-02. PMID:9422389. |
the major active ingredient of marijuana, (-)-delta9-tetrahydrocannabinol, exerts its psychoactive effects via binding to cannabinoid cb1 receptors, which are widely distributed in the brain. |
1998-02-02 |
2023-08-12 |
mouse |
| D R Compton, B R Marti. The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. The Journal of pharmacology and experimental therapeutics. vol 283. issue 3. 1998-01-15. PMID:9399986. |
anandamide is an putative endogenous cannabinoid ligand that produces pharmacological effects similar to those of delta9-tetrahydrocannabinol, the principle psychoactive constituent in marijuana. |
1998-01-15 |
2023-08-12 |
mouse |
| T Lehmann, F Sager, R Brenneise. Excretion of cannabinoids in urine after ingestion of cannabis seed oil. Journal of analytical toxicology. vol 21. issue 5. 1997-12-29. PMID:9288590. |
excretion of cannabinoids in urine after ingestion of cannabis seed oil. |
1997-12-29 |
2023-08-12 |
human |
| J A Wagner, K Varga, E F Ellis, B A Rzigalinski, B R Martin, G Kuno. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. Nature. vol 390. issue 6659. 1997-12-22. PMID:9394002. |
anandamide, an endogenous cannabinoid ligand, binds to cb1 cannabinoid receptors in the brain and mimics the neurobehavioural actions of marijuana. |
1997-12-22 |
2023-08-12 |
rat |
| M E Brewster, E Pop, R L Foltz, S Reuschel, W Griffith, S Amselem, A Biego. Clinical pharmacokinetics of escalating i.v. doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers. International journal of clinical pharmacology and therapeutics. vol 35. issue 9. 1997-11-18. PMID:9314087. |
these data are similar to those reported for naturally occurring cannabinoids such as delta 9-tetrahydrocannabinol and cannabidiol. |
1997-11-18 |
2023-08-12 |
human |
| Y Mikawa, S Matsuda, T Kanagawa, T Tajika, N Ueda, Y Mimur. Ocular activity of topically administered anandamide in the rabbit. Japanese journal of ophthalmology. vol 41. issue 4. 1997-10-27. PMID:9304433. |
marijuana and its psychoactive constituents, cannabinoids, reduce intraocular pressure (iop) in humans and animals. |
1997-10-27 |
2023-08-12 |
rabbit |
| J Brodkin, J M Moerschbaeche. SR141716A antagonizes the disruptive effects of cannabinoid ligands on learning in rats. The Journal of pharmacology and experimental therapeutics. vol 282. issue 3. 1997-10-17. PMID:9316868. |
neither injections of the centrally inactive cannabinoid, cannabidiol (3.2-100 mg/kg i.p. |
1997-10-17 |
2023-08-12 |
rat |
| P Consroe, R Musty, J Rein, W Tillery, R Pertwe. The perceived effects of smoked cannabis on patients with multiple sclerosis. European neurology. vol 38. issue 1. 1997-10-15. PMID:9252798. |
the survey findings will aid in the design of a clinical trial of cannabis or cannabinoid administration to ms patients or to other patients with similar signs or symptoms. |
1997-10-15 |
2023-08-12 |
human |
| N Stella, P Schweitzer, D Piomell. A second endogenous cannabinoid that modulates long-term potentiation. Nature. vol 388. issue 6644. 1997-09-22. PMID:9285589. |
cannabinoid receptors are molecular targets for marijuana and hashish, the widespread drugs of abuse. |
1997-09-22 |
2023-08-12 |
Not clear |
| G L Gessa, M S Mascia, M A Casu, G Cart. Inhibition of hippocampal acetylcholine release by cannabinoids: reversal by SR 141716A. European journal of pharmacology. vol 327. issue 1. 1997-07-29. PMID:9185841. |
the results also suggest that the negative effects of marijuana on learning and memory may depend on cannabinoid receptor-mediated inhibition of acetylcholine release. |
1997-07-29 |
2023-08-12 |
rat |
| E D French, K Dillon, X W. Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra. Neuroreport. vol 8. issue 3. 1997-07-03. PMID:9106740. |
these results may provide a mechanism by which psychoactive cannabinoids increase extracellular dopamine levels in mesolimbic and striatal tissues, and thereby contribute to the reinforcing effects of marijuana. |
1997-07-03 |
2023-08-12 |
Not clear |
| A Holdcroft, M Smith, A Jacklin, H Hodgson, B Smith, M Newton, F Evan. Pain relief with oral cannabinoids in familial Mediterranean fever. Anaesthesia. vol 52. issue 5. 1997-06-13. PMID:9165969. |
future study designs can now incorporate prescribable forms of cannabinoids but the choice of previous cannabis users only as patients has clinical limitations. |
1997-06-13 |
2023-08-12 |
Not clear |
| M S Smith, Y Yamamoto, C Newton, H Friedman, T Klei. Psychoactive cannabinoids increase mortality and alter acute phase cytokine responses in mice sublethally infected with Legionella pneumophila. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 214. issue 1. 1997-02-20. PMID:9012363. |
marijuana contains both psychoactive and nonpsychoactive cannabinoids which have varying effects on the immune response system. |
1997-02-20 |
2023-08-12 |
mouse |
| M S Smith, Y Yamamoto, C Newton, H Friedman, T Klei. Psychoactive cannabinoids increase mortality and alter acute phase cytokine responses in mice sublethally infected with Legionella pneumophila. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 214. issue 1. 1997-02-20. PMID:9012363. |
the present study compared the enhancement of legionella-induced mortality in mice due to two other major of marijuana components, cannabinol and cannabidiol, as well as the synthetic psychoactive cannabinoid cp 55,940. |
1997-02-20 |
2023-08-12 |
mouse |