| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Garry Milman, Allan J Barnes, Ross H Lowe, Marilyn A Huesti. Simultaneous quantification of cannabinoids and metabolites in oral fluid by two-dimensional gas chromatography mass spectrometry. Journal of chromatography. A. vol 1217. issue 9. 2010-05-03. PMID:20083251. |
this method will be applied to quantification of cannabinoids in oral fluid specimens from individuals participating in controlled cannabis and sativex (50% thc and 50% cbd) administration studies, and during cannabis withdrawal. |
2010-05-03 |
2023-08-12 |
Not clear |
| Dana Turcotte, Josée-Anne Le Dorze, Farid Esfahani, Emma Frost, Andrew Gomori, Mike Namak. Examining the roles of cannabinoids in pain and other therapeutic indications: a review. Expert opinion on pharmacotherapy. vol 11. issue 1. 2010-04-28. PMID:20001426. |
with expanding knowledge, synthetic cannabinoids - including nabilone, dronabinol and a combination of synthetic delta9-thc and cannabidiol - have been developed and tested for benefit in a variety of therapeutic indications. |
2010-04-28 |
2023-08-12 |
Not clear |
| Frances R Levin, John J Mariani, Daniel J Brooks, Shan Xie, Kathleen A Murra. Delta9-tetrahydrocannabivarin testing may not have the sensitivity to detect marijuana use among individuals ingesting dronabinol. Drug and alcohol dependence. vol 106. issue 1. 2010-04-09. PMID:19733018. |
the purpose of this study was to determine whether delta(9)-tetrahydrocannabivarin (thcv), a plant cannabinoid, is a sensitive measure to detect recent marijuana use in cannabis dependent patients. |
2010-04-09 |
2023-08-12 |
Not clear |
| C Clinton Frazee, Michael Kiscoan, Uttam Gar. Quantitation of total 11-nor-9-carboxy-delta 9-tetrahydrocannabinol in urine and blood using gas chromatography-mass spectrometry (GC-MS). Methods in molecular biology (Clifton, N.J.). vol 603. 2010-04-05. PMID:20077066. |
marijuana, which is made from crushing the leaves, flowers, and sometimes the stems of the plant cannabis sativa, contains more than 30 cannabinoids. |
2010-04-05 |
2023-08-12 |
Not clear |
| Francesca Borrelli, Gabriella Aviello, Barbara Romano, Pierangelo Orlando, Raffaele Capasso, Francesco Maiello, Federico Guadagno, Stefania Petrosino, Francesco Capasso, Vincenzo Di Marzo, Angelo A Izz. Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis. Journal of molecular medicine (Berlin, Germany). vol 87. issue 11. 2010-03-25. PMID:19690824. |
cannabidiol reduced colon injury, inducible inos (but not cyclooxygenase-2) expression, and interleukin-1beta, interleukin-10, and endocannabinoid changes associated with 2,4,6-dinitrobenzene sulfonic acid administration. |
2010-03-25 |
2023-08-12 |
mouse |
| Diego Centonze, Francesco Mori, Giacomo Koch, Fabio Buttari, Claudia Codecà, Silvia Rossi, Maria Teresa Cencioni, Monica Bari, Stefania Fiore, Giorgio Bernardi, Luca Battistini, Mauro Maccarron. Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 30. issue 6. 2010-03-22. PMID:19768368. |
the endocannabinoid system (ecs) is involved in the pathophysiology of multiple sclerosis (ms), and relief from pain and spasticity has been reported in ms patients self-medicating with marijuana. |
2010-03-22 |
2023-08-12 |
Not clear |
| Jahan P Marcu, Rigel T Christian, Darryl Lau, Anne J Zielinski, Maxx P Horowitz, Jasmine Lee, Arash Pakdel, Juanita Allison, Chandani Limbad, Dan H Moore, Garret L Yount, Pierre-Yves Desprez, Sean D McAlliste. Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival. Molecular cancer therapeutics. vol 9. issue 1. 2010-03-22. PMID:20053780. |
we therefore tested cannabidiol, the second most abundant plant-derived cannabinoid, in combination with delta(9)-thc. |
2010-03-22 |
2023-08-12 |
human |
| Mathieu Lafourcade, Izaskun Elezgarai, Susana Mato, Yamina Bakiri, Pedro Grandes, Olivier J Manzon. Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. PloS one. vol 2. issue 8. 2010-03-12. PMID:17684555. |
cannabinoids have deleterious effects on prefrontal cortex (pfc)-mediated functions and multiple evidences link the endogenous cannabinoid (endocannabinoid) system, cannabis use and schizophrenia, a disease in which pfc functions are altered. |
2010-03-12 |
2023-08-12 |
mouse |
| Itai Bab, Andreas Zimmer, Eitan Melame. Cannabinoids and the skeleton: from marijuana to reversal of bone loss. Annals of medicine. vol 41. issue 8. 2010-03-09. PMID:19634029. |
cannabinoids and the skeleton: from marijuana to reversal of bone loss. |
2010-03-09 |
2023-08-12 |
mouse |
| Itai Bab, Andreas Zimmer, Eitan Melame. Cannabinoids and the skeleton: from marijuana to reversal of bone loss. Annals of medicine. vol 41. issue 8. 2010-03-09. PMID:19634029. |
the active component of marijuana, delta(9)-tetrahydrocannabinol, activates the cb1 and cb2 cannabinoid receptors, thus mimicking the action of endogenous cannabinoids. |
2010-03-09 |
2023-08-12 |
mouse |
| Eric J Downer, Veronica A Campbel. Phytocannabinoids, CNS cells and development: a dead issue? Drug and alcohol review. vol 29. issue 1. 2010-03-03. PMID:20078688. |
marijuana and hashish consist of at least 66 distinctive plant-derived (phyto-) cannabinoid compounds, with tetrahydrocannabinoids proving the most effective phytocannabinoid psychotropically. |
2010-03-03 |
2023-08-12 |
Not clear |
| Justin T Fischedick, Ronald Glas, Arno Hazekamp, Rob Verpoort. A qualitative and quantitative HPTLC densitometry method for the analysis of cannabinoids in Cannabis sativa L. Phytochemical analysis : PCA. vol 20. issue 5. 2010-03-02. PMID:19609880. |
a qualitative and quantitative hptlc densitometry method for the analysis of cannabinoids in cannabis sativa l. cannabis and cannabinoid based medicines are currently under serious investigation for legitimate development as medicinal agents, necessitating new low-cost, high-throughput analytical methods for quality control. |
2010-03-02 |
2023-08-12 |
Not clear |
| Robert Ramer, Jutta Merkord, Helga Rohde, Burkhard Hin. Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. Biochemical pharmacology. vol 79. issue 7. 2010-03-02. PMID:19914218. |
here we evaluated the impact of cannabidiol, a plant-derived non-psychoactive cannabinoid, on cancer cell invasion. |
2010-03-02 |
2023-08-12 |
mouse |
| Gilberto Gerra, Amir Zaimovic, Maria L Gerra, Roberto Ciccocioppo, Andrea Cippitelli, Giovanni Serpelloni, Lorenzo Somain. Pharmacology and toxicology of Cannabis derivatives and endocannabinoid agonists. Recent patents on CNS drug discovery. vol 5. issue 1. 2010-03-01. PMID:19832688. |
pharmacology and toxicology of cannabis derivatives and endocannabinoid agonists. |
2010-03-01 |
2023-08-12 |
Not clear |
| Daniela Vigano, Cinzia Guidali, Stefania Petrosino, Natalia Realini, Tiziana Rubino, Vincenzo Di Marzo, Daniela Parolar. Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia. The international journal of neuropsychopharmacology. vol 12. issue 5. 2010-02-12. PMID:18789179. |
recent advances in the neurobiology of cannabinoids have renewed interest in the association between cannabis and schizophrenia. |
2010-02-12 |
2023-08-12 |
rat |
| Daniela Vigano, Cinzia Guidali, Stefania Petrosino, Natalia Realini, Tiziana Rubino, Vincenzo Di Marzo, Daniela Parolar. Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia. The international journal of neuropsychopharmacology. vol 12. issue 5. 2010-02-12. PMID:18789179. |
moreover, we evaluated the ability of the main psychoactive ingredient of marijuana, delta9-tetrahydrocannabinol (thc), to modulate the cognitive dysfunctions and neuroadaptations in the endocannabinoid system induced by pcp. |
2010-02-12 |
2023-08-12 |
rat |
| Daniela Vigano, Cinzia Guidali, Stefania Petrosino, Natalia Realini, Tiziana Rubino, Vincenzo Di Marzo, Daniela Parolar. Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia. The international journal of neuropsychopharmacology. vol 12. issue 5. 2010-02-12. PMID:18789179. |
these results point to the involvement of the endocannabinoid system in this pharmacological model of cognitive dysfunction, with a potentially different role of aea and 2-ag in schizophrenia-like behaviours and suggest that prolonged cannabis use might aggravate cognitive performances induced by chronic pcp by throwing off-balance the endocannabinoid system. |
2010-02-12 |
2023-08-12 |
rat |
| Ewa Kozela, Maciej Pietr, Ana Juknat, Neta Rimmerman, Rivka Levy, Zvi Voge. Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells. The Journal of biological chemistry. vol 285. issue 3. 2010-02-08. PMID:19910459. |
cannabinoids delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated nf-kappab and interferon-beta/stat proinflammatory pathways in bv-2 microglial cells. |
2010-02-08 |
2023-08-12 |
mouse |
| Ewa Kozela, Maciej Pietr, Ana Juknat, Neta Rimmerman, Rivka Levy, Zvi Voge. Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells. The Journal of biological chemistry. vol 285. issue 3. 2010-02-08. PMID:19910459. |
we found that the two major cannabinoids present in marijuana, delta(9)-tetrahydrocannabinol (thc) and cannabidiol (cbd), decrease the production and release of proinflammatory cytokines, including interleukin-1beta, interleukin-6, and interferon (ifn)beta, from lps-activated microglial cells. |
2010-02-08 |
2023-08-12 |
mouse |
| Benjamin De Backer, Benjamin Debrus, Pierre Lebrun, Laetitia Theunis, Nathalie Dubois, Lies Decock, Alain Verstraete, Philippe Hubert, Corinne Charlie. Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 877. issue 32. 2010-02-05. PMID:19932642. |
innovative development and validation of an hplc/dad method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material. |
2010-02-05 |
2023-08-12 |
Not clear |