| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dayong Lee, Ryan Vandrey, Garry Milman, Mateus Bergamaschi, Damodara R Mendu, Jeannie A Murray, Allan J Barnes, Marilyn A Huesti. Oral fluid/plasma cannabinoid ratios following controlled oral THC and smoked cannabis administration. Analytical and bioanalytical chemistry. vol 405. issue 23. 2014-10-27. PMID:23831756. |
oral fluid/plasma cannabinoid ratios following controlled oral thc and smoked cannabis administration. |
2014-10-27 |
2023-08-12 |
Not clear |
| Rikki L A Miller, Ganesh A Thakur, William N Stewart, Joshua P Bow, Shama Bajaj, Alexandros Makriyannis, Peter J McLaughli. Effects of a novel CB1 agonist on visual attention in male rats: role of strategy and expectancy in task accuracy. Experimental and clinical psychopharmacology. vol 21. issue 5. 2014-10-27. PMID:24099361. |
the effects of cannabinoid cb1 agonists (including Δ9-tetrahydrocannabinol, the main psychoactive component of marijuana) on attention are uncertain, with reports of impairments, no effects, and occasionally performance enhancements. |
2014-10-27 |
2023-08-12 |
rat |
| Jone Omar, Maitane Olivares, José Manuel Amigo, Nestor Etxebarri. Resolution of co-eluting compounds of Cannabis Sativa in comprehensive two-dimensional gas chromatography/mass spectrometry detection with Multivariate Curve Resolution-Alternating Least Squares. Talanta. vol 121. 2014-10-27. PMID:24607138. |
comprehensive two dimensional gas chromatography - mass spectrometry (gc × gc/qms) analysis of cannabis sativa extracts shows a high complexity due to the large variety of terpenes and cannabinoids and to the fact that the complete resolution of the peaks is not straightforwardly achieved. |
2014-10-27 |
2023-08-12 |
Not clear |
| Jone Omar, Maitane Olivares, José Manuel Amigo, Nestor Etxebarri. Resolution of co-eluting compounds of Cannabis Sativa in comprehensive two-dimensional gas chromatography/mass spectrometry detection with Multivariate Curve Resolution-Alternating Least Squares. Talanta. vol 121. 2014-10-27. PMID:24607138. |
as a result, four co-eluting areas were totally resolved in the sesquiterpene region and one in the cannabinoid region in different samples of cannabis sativa. |
2014-10-27 |
2023-08-12 |
Not clear |
| Nathalie A Desrosiers, Dayong Lee, Karl B Scheidweiler, Marta Concheiro-Guisan, David A Gorelick, Marilyn A Huesti. In vitro stability of free and glucuronidated cannabinoids in urine following controlled smoked cannabis. Analytical and bioanalytical chemistry. vol 406. issue 3. 2014-10-13. PMID:24292435. |
in vitro stability of free and glucuronidated cannabinoids in urine following controlled smoked cannabis. |
2014-10-13 |
2023-08-12 |
human |
| Meggie D Caldwell, Sherry Shu-Jung Hu, Suresh Viswanathan, Heather Bradshaw, Melanie E M Kelly, Alex Straike. A GPR18-based signalling system regulates IOP in murine eye. British journal of pharmacology. vol 169. issue 4. 2014-10-08. PMID:23461720. |
gpr18 is a recently deorphaned lipid receptor that is activated by the endogenous lipid n-arachidonoyl glycine (nagly) as well the behaviourally inactive atypical cannabinoid, abnormal cannabidiol (abn-cbd). |
2014-10-08 |
2023-08-12 |
mouse |
| Sara Jane Ward, Sean D McAllister, Rumi Kawamura, Ryuchi Murase, Harshini Neelakantan, Ellen A Walke. Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT(1A) receptors without diminishing nervous system function or chemotherapy efficacy. British journal of pharmacology. vol 171. issue 3. 2014-10-07. PMID:24117398. |
we previously reported that chronic administration of the non-psychoactive cannabinoid cannabidiol (cbd) prevents pac-induced mechanical and thermal sensitivity in mice. |
2014-10-07 |
2023-08-12 |
mouse |
| P P Basu, M M Aloysius, N J Shah, R S Brow. Review article: the endocannabinoid system in liver disease, a potential therapeutic target. Alimentary pharmacology & therapeutics. vol 39. issue 8. 2014-09-26. PMID:24612021. |
endocannabinoids are a family of potent lipid-soluble molecules, acting on the cannabinoid (cb) receptors that mediate the effects of marijuana. |
2014-09-26 |
2023-08-12 |
Not clear |
| Balapal S Basavarajappa, Shivakumar Subbann. CB1 receptor-mediated signaling underlies the hippocampal synaptic, learning, and memory deficits following treatment with JWH-081, a new component of spice/K2 preparations. Hippocampus. vol 24. issue 2. 2014-09-23. PMID:24123667. |
recently, synthetic cannabinoids have been sprayed onto plant material, which is subsequently packaged and sold as "spice" or "k2" to mimic the effects of marijuana. |
2014-09-23 |
2023-08-12 |
mouse |
| Natasa Radosavljevic-Stevanovic, Jelena Markovic, Snezana Agatonovic-Kustrin, Slavica Razi. Metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of Cannabis sativa samples. Natural product research. vol 28. issue 8. 2014-09-22. PMID:24483128. |
metals and organic compounds in the biosynthesis of cannabinoids: a chemometric approach to the analysis of cannabis sativa samples. |
2014-09-22 |
2023-08-12 |
Not clear |
| Lisa K Brents, Paul L Prathe. The K2/Spice phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products. Drug metabolism reviews. vol 46. issue 1. 2014-09-16. PMID:24063277. |
in 2008, the european monitoring center for drugs and drug addiction (emcdda) detected unregulated, psychoactive synthetic cannabinoids (scbs) in purportedly all-natural herbal incense products (often known as k2 or spice) that were being covertly abused as marijuana substitutes. |
2014-09-16 |
2023-08-12 |
Not clear |
| Stephen M Stout, Nina M Cimin. Exogenous cannabinoids as substrates, inhibitors, and inducers of human drug metabolizing enzymes: a systematic review. Drug metabolism reviews. vol 46. issue 1. 2014-09-16. PMID:24160757. |
in vitro data were identified that characterize cytochrome p-450 (cyp-450) enzymes as potential significant contributors to the primary metabolism of several exogenous cannabinoids: tetrahydrocannabinol (thc; cyps 2c9, 3a4); cannabidiol (cbd; cyps 2c19, 3a4); cannabinol (cbn; cyps 2c9, 3a4); jwh-018 (cyps 1a2, 2c9); and am2201 (cyps 1a2, 2c9). |
2014-09-16 |
2023-08-12 |
human |
| Stephen M Stout, Nina M Cimin. Exogenous cannabinoids as substrates, inhibitors, and inducers of human drug metabolizing enzymes: a systematic review. Drug metabolism reviews. vol 46. issue 1. 2014-09-16. PMID:24160757. |
smoked cannabis herb (marijuana) likely induces cyp1a2 mediated theophylline metabolism, although the role of cannabinoids specifically in eliciting this effect is questionable. |
2014-09-16 |
2023-08-12 |
human |
| L A Kin. Legal controls on cannabimimetics: an international dilemma? Drug testing and analysis. vol 6. issue 1-2. 2014-09-15. PMID:23881527. |
these cannabinoids typically act as agonists at cb1 receptors, and mimic the effects of Δ(9)-tetrahydrocannabinol (thc), the principal psychoactive constituent of cannabis l. as with other 'new psychoactive substances', they have shown the limitations of current drug control procedures. |
2014-09-15 |
2023-08-12 |
human |
| P J Robso. Therapeutic potential of cannabinoid medicines. Drug testing and analysis. vol 6. issue 1-2. 2014-09-15. PMID:24006213. |
in the forefront of clinical research are the cannabinoids delta-9-tetrahydrocannabinol and cannabidiol, and their contrasting pharmacology will be briefly outlined. |
2014-09-15 |
2023-08-12 |
Not clear |
| David J Potte. A review of the cultivation and processing of cannabis (Cannabis sativa L.) for production of prescription medicines in the UK. Drug testing and analysis. vol 6. issue 1-2. 2014-09-15. PMID:24115748. |
to produce the complex botanical medicine sativex®, which contains the cannabinoids Δ(9)-tetrahydrocannabinol (thc) and cannabidiol (cbd) and a range of other ingredients, gw pharmaceuticals had to manage these variables. |
2014-09-15 |
2023-08-12 |
Not clear |
| Silvana Y Romero-Zerbo, Francisco J Bermúdez-Silv. Cannabinoids, eating behaviour, and energy homeostasis. Drug testing and analysis. vol 6. issue 1-2. 2014-09-15. PMID:24375977. |
however, investigation into the molecular action of the main constituents of cannabis has led to the discovery of an intercellular signalling system, called the endocannabinoid system (ecs). |
2014-09-15 |
2023-08-12 |
Not clear |
| Luan C Koay, Rachael J Rigby, Karen L Wrigh. Cannabinoid-induced autophagy regulates suppressor of cytokine signaling-3 in intestinal epithelium. American journal of physiology. Gastrointestinal and liver physiology. vol 307. issue 2. 2014-09-12. PMID:24833710. |
by assessing the impact of the phytocannabinoid cannabidiol (cbd), the synthetic cannabinoid arachidonyl-2'-chloroethylamide (acea), and the endocannabinoid n-arachidonoylethanolamine (aea) on autophagosome formation, we explored whether these actions were responsible for cyclic socs3 protein levels. |
2014-09-12 |
2023-08-13 |
Not clear |
| Ahmet Ulugö. The endocannabinoid system as a potential therapeutic target for pain modulation. Balkan medical journal. vol 31. issue 2. 2014-09-10. PMID:25207181. |
although cannabis has been used for pain management for millennia, very few approved cannabinoids are indicated for the treatment of pain and other medical symptoms. |
2014-09-10 |
2023-08-13 |
Not clear |
| Frank Musshoff, Burkhard Madea, Gerhard Kernbach-Wighton, Wolfgang Bicker, Stefan Kneisel, Melanie Hutter, Volker Auwärte. Driving under the influence of synthetic cannabinoids ("Spice"): a case series. International journal of legal medicine. vol 128. issue 1. 2014-09-09. PMID:23636569. |
consumption of synthetic cannabinoids can lead to impairment similar to typical performance deficits caused by cannabis use which are not compatible with safe driving. |
2014-09-09 |
2023-08-12 |
Not clear |