| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kimberly L Samano, Justin L Poklis, Aron H Lichtman, Alphonse Pokli. Development of a high-performance liquid chromatography-tandem mass spectrometry method for the identification and quantification of CP-47,497, CP-47,497-C8 and JWH-250 in mouse brain. Journal of analytical toxicology. vol 38. issue 6. 2015-06-01. PMID:24816398. |
while marijuana continues to be the most widely used illicit drug, abuse of synthetic cannabinoid (scb) compounds in 'spice' or 'k2' herbal incense products has emerged as a significant public health concern in many european countries and in the usa. |
2015-06-01 |
2023-08-13 |
mouse |
| M Wierucka-Rybak, M Wolak, E Bojanowsk. The effects of leptin in combination with a cannabinoid receptor 1 antagonist, AM 251, or cannabidiol on food intake and body weight in rats fed a high-fat or a free-choice high sugar diet. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 65. issue 4. 2015-05-18. PMID:25179081. |
to further investigate whether simultaneous pharmacological intervention in the leptin and cannabinoid system might change food and water intake, preferences for palatable foods, and body weight, we have examined the effects of concomitant intraperitoneal administration of leptin and am 251, a cannabinoid 1 (cb1) receptor antagonist, or cannabidiol (cbd), a plant cannabinoid, in rats maintained on either a high-fat (hf) diet (45% energy from fat) or free-choice (fc) diet consisting of high-sucrose and normal rat chow (83% and 61% energy from carbohydrates, respectively). |
2015-05-18 |
2023-08-13 |
rat |
| Parijat Kusari, Souvik Kusari, Michael Spiteller, Oliver Kayse. Biocontrol potential of endophytes harbored in Radula marginata (liverwort) from the New Zealand ecosystem. Antonie van Leeuwenhoek. vol 106. issue 4. 2015-05-15. PMID:25100187. |
radula marginata and cannabis sativa l. are two phylogenetically unrelated plant species containing structurally similar secondary metabolites like cannabinoids. |
2015-05-15 |
2023-08-13 |
Not clear |
| Michelle Sexton, Eiron Cudaback, Rehab A Abdullah, John Finnell, Laurie K Mischley, Mary Rozga, Aron H Lichtman, Nephi Stell. Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters. Inflammopharmacology. vol 22. issue 5. 2015-05-15. PMID:25135301. |
we detected a significant increase in the endocannabinoid arachidonoylethanolamine (aea) in serum from individuals with ms compared to control subjects, and no significant difference in levels of other endocannabinoids and signaling lipids irrespective of cannabis use. |
2015-05-15 |
2023-08-13 |
human |
| Rebecca A Kohnz, Daniel K Nomur. Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoids. Chemical Society reviews. vol 43. issue 19. 2015-05-14. PMID:24676249. |
the endocannabinoid system, most popularly known as the target of the psychoactive component of marijuana, Δ(9)-tetrahydrocannabinol (thc), is a signaling network that modulates a diverse range of physiological processes including nociception, behavior, cognitive function, appetite, metabolism, motor control, memory formation, and inflammation. |
2015-05-14 |
2023-08-12 |
Not clear |
| Shin Fukuda, Hitoshi Kohsaka, Aiko Takayasu, Waka Yokoyama, Chie Miyabe, Yoshishige Miyabe, Masayoshi Harigai, Nobuyuki Miyasaka, Toshihiro Nank. Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis. BMC musculoskeletal disorders. vol 15. 2015-05-12. PMID:25115332. |
some of cannabinoids, which are chemical compounds contained in marijuana, are immunosuppressive. |
2015-05-12 |
2023-08-13 |
Not clear |
| Nathalie A Desrosiers, Garry Milman, Damodara R Mendu, Dayong Lee, Allan J Barnes, David A Gorelick, Marilyn A Huesti. Cannabinoids in oral fluid by on-site immunoassay and by GC-MS using two different oral fluid collection devices. Analytical and bioanalytical chemistry. vol 406. issue 17. 2015-05-11. PMID:24828976. |
furthermore, as far as we are aware, no studies have evaluated differences between cannabinoid disposition among of collection devices with authentic of samples after controlled cannabis administration. |
2015-05-11 |
2023-08-13 |
Not clear |
| Kenji Kuwayama, Tadashi Yamamuro, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T Iwata, Hiroyuki Inou. Utilization of matrix-assisted laser desorption/ionization imaging mass spectrometry to search for cannabis in herb mixtures. Analytical and bioanalytical chemistry. vol 406. issue 19. 2015-05-11. PMID:24838491. |
when cannabinoids from herb extracts are detected by chemical examinations such as gas chromatography/mass spectrometry, forensic analysts have to determine whether cannabis is actually in the mixture or the cannabinoids are spiked. |
2015-05-11 |
2023-08-13 |
Not clear |
| Raj Makwana, Radhakrishnan Venkatasamy, Domenico Spina, Clive Pag. The effect of phytocannabinoids on airway hyper-responsiveness, airway inflammation, and cough. The Journal of pharmacology and experimental therapeutics. vol 353. issue 1. 2015-05-09. PMID:25655949. |
cannabis has been demonstrated to have bronchodilator, anti-inflammatory, and antitussive activity in the airways, but information on the active cannabinoids, their receptors, and the mechanisms for these effects is limited. |
2015-05-09 |
2023-08-13 |
Not clear |
| Joan L Krame. Medical marijuana for cancer. CA: a cancer journal for clinicians. vol 65. issue 2. 2015-05-05. PMID:25503438. |
this article will review the literature regarding the medical use of marijuana and these cannabinoid pharmaceuticals (with emphasis on indications relevant to oncology), as well as available information regarding adverse effects of marijuana use. |
2015-05-05 |
2023-08-13 |
Not clear |
| Timothy J England, William H Hind, Nadiah A Rasid, Saoirse E O'Sulliva. Cannabinoids in experimental stroke: a systematic review and meta-analysis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 35. issue 3. 2015-04-20. PMID:25492113. |
cannabinoids reduced infarct volume in transient (smd -1.41 (95% ci -1.71), -1.11) p<0.00001) and permanent (-1.67 (-2.08, -1.27), p<0.00001) ischemia and in all subclasses: endocannabinoids (-1.72 (-2.62, -0.82), p=0.0002), cb1/cb2 ligands (-1.75 (-2.19, -1.31), p<0.00001), cb2 ligands (-1.65 (-2.09, -1.22), p<0.00001), cannabidiol (-1.20 (-1.63, -0.77), p<0.00001), Δ(9)-tetrahydrocannabinol (-1.43 (-2.01, -0.86), p<0.00001), and hu-211 (-2.90 (-4.24, -1.56), p<0.0001). |
2015-04-20 |
2023-08-13 |
Not clear |
| David Baker, Gareth Pryce, Samuel J Jackson, Chris Bolton, Gavin Giovannon. The biology that underpins the therapeutic potential of cannabis-based medicines for the control of spasticity in multiple sclerosis. Multiple sclerosis and related disorders. vol 1. issue 2. 2015-04-17. PMID:25876933. |
this activity is supported both by the biology of the disease and the biology of the cannabis plant and the endocannabinoid system. |
2015-04-17 |
2023-08-13 |
Not clear |
| Takashi Ashino, Kanae Hakukawa, Yuka Itoh, Satoshi Numazaw. Inhibitory effect of synthetic cannabinoids on CYP1A activity in mouse liver microsomes. The Journal of toxicological sciences. vol 39. issue 6. 2015-04-16. PMID:25374372. |
synthetic cannabinoids developed by chemical modification are believed to bind to cannabinoid receptors and cause neurological effects similar to cannabis; however, their effects on drug metabolizing enzymes are unknown. |
2015-04-16 |
2023-08-13 |
mouse |
| Steven B Karc. Cannabis and cardiotoxicity. Forensic science, medicine, and pathology. vol 2. issue 1. 2015-04-15. PMID:25868498. |
cannabinoids, the active compounds contained in marijuana, interact with cardiovascular centers in the brain, but also exert direct effects on vascular tone. |
2015-04-15 |
2023-08-13 |
Not clear |
| Maureen T Cruz, Michal Bajo, Paul Schweitzer, Marisa Robert. Shared mechanisms of alcohol and other drugs. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism. vol 31. issue 2. 2015-04-13. PMID:23584815. |
thus, cannabis and opiates act via receptors intended for internally derived (i.e., endogenous) cannabinoid and opiate substances. |
2015-04-13 |
2023-08-12 |
Not clear |
| Erik W Gunderson, Heather M Haughey, Nassima Ait-Daoud, Amruta S Joshi, Carl L Har. A survey of synthetic cannabinoid consumption by current cannabis users. Substance abuse. vol 35. issue 2. 2015-04-13. PMID:24821356. |
a survey of synthetic cannabinoid consumption by current cannabis users. |
2015-04-13 |
2023-08-13 |
Not clear |
| D Greydanus, M Hol. Cannabis: a controversial 21st-century drug of antiquity. Georgian medical news. issue 230. 2015-04-13. PMID:24940853. |
this discussion considers various aspects of cannabis use including its prevalence, history, co-morbid drug abuse, designer cannabinoids, psychiatric adverse effects, medical adverse effects, and management options. |
2015-04-13 |
2023-08-13 |
Not clear |
| Mallory Loflin, Mitch Earleywin. A new method of cannabis ingestion: the dangers of dabs? Addictive behaviors. vol 39. issue 10. 2015-04-10. PMID:24930049. |
a new method for administering cannabinoids, called butane hash oil ("dabs"), is gaining popularity among marijuana users. |
2015-04-10 |
2023-08-13 |
Not clear |
| Daniël Kleinloog, Frits Roozen, Willem De Winter, Jan Freijer, Joop Van Gerve. Profiling the subjective effects of Δ⁹-tetrahydrocannabinol using visual analogue scales. International journal of methods in psychiatric research. vol 23. issue 2. 2015-04-06. PMID:24496889. |
the subjective effects of cannabis and its main psychoactive component Δ(9) -tetrahydrocannabinol (thc) have played an important part in determining the therapeutic potential of cannabinoid agonists and antagonists. |
2015-04-06 |
2023-08-12 |
human |
| Thangam Venkatesan, Jyotirmoy Sengupta, Atena Lodhi, Abigail Schroeder, Kathleen Adams, Walter J Hogan, Yanzhi Wang, Christopher Andrews, Martin Stor. An Internet survey of marijuana and hot shower use in adults with cyclic vomiting syndrome (CVS). Experimental brain research. vol 232. issue 8. 2015-04-06. PMID:24792504. |
several case reports implicate marijuana as a cause of intractable vomiting with compulsive hot water bathing considered pathognomonic of "cannabinoid hyperemesis." |
2015-04-06 |
2023-08-13 |
Not clear |