Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Marisol S Castaneto, David A Gorelick, Nathalie A Desrosiers, Rebecca L Hartman, Sandrine Pirard, Marilyn A Huesti. Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications. Drug and alcohol dependence. vol 144. 2015-10-30. PMID:25220897. |
the majority of sc detected in herbal products have greater binding affinity to the cannabinoid cb1 receptor than does Δ(9)-tetrahydrocannabinol (thc), the primary psychoactive compound in the cannabis plant, and greater affinity at the cb1 than the cb2 receptor. |
2015-10-30 |
2023-08-13 |
human |
Andreas Austgulen Westin, George Mjønes, Ola Burchardt, Ole Martin Fuskevåg, Lars Slørda. Can physical exercise or food deprivation cause release of fat-stored cannabinoids? Basic & clinical pharmacology & toxicology. vol 115. issue 5. 2015-10-26. PMID:24674455. |
the aim of this study was to evaluate whether physical exercise or food deprivation may increase cannabinoid levels in serum or urine in abstinent chronic cannabis users. |
2015-10-26 |
2023-08-12 |
human |
Jenny Ceccarini, Rebecca Kuepper, Dieter Kemels, Jim van Os, Cécile Henquet, Koen Van Laer. [18F]MK-9470 PET measurement of cannabinoid CB1 receptor availability in chronic cannabis users. Addiction biology. vol 20. issue 2. 2015-10-21. PMID:24373053. |
[18f]mk-9470 pet measurement of cannabinoid cb1 receptor availability in chronic cannabis users. |
2015-10-21 |
2023-08-12 |
human |
Jenny Ceccarini, Rebecca Kuepper, Dieter Kemels, Jim van Os, Cécile Henquet, Koen Van Laer. [18F]MK-9470 PET measurement of cannabinoid CB1 receptor availability in chronic cannabis users. Addiction biology. vol 20. issue 2. 2015-10-21. PMID:24373053. |
Δ(9) -tetrahydrocannabinol, the main psychoactive component of cannabis, exerts its central effects through activation of the cerebral type 1 cannabinoid (cb1 ) receptor. |
2015-10-21 |
2023-08-12 |
human |
Marie Fabritius, Marc Augsburger, Haithem Chtioui, Bernard Favrat, Christian Girou. Fitness to drive and cannabis: validation of two blood THCCOOH thresholds to distinguish occasional users from heavy smokers. Forensic science international. vol 242. 2015-10-21. PMID:24999608. |
their validity can now be evaluated and confirmed with 146 traffic offenders' real cases in which the whole blood cannabinoid concentrations and the frequency of cannabis use are known. |
2015-10-21 |
2023-08-13 |
human |
Tom P Freeman, Celia J A Morgan, Chandni Hindocha, Gráinne Schafer, Ravi K Das, H Valerie Curra. Just say 'know': how do cannabinoid concentrations influence users' estimates of cannabis potency and the amount they roll in joints? Addiction (Abingdon, England). vol 109. issue 10. 2015-10-20. PMID:24894801. |
just say 'know': how do cannabinoid concentrations influence users' estimates of cannabis potency and the amount they roll in joints? |
2015-10-20 |
2023-08-13 |
Not clear |
Dante Durand, Leticia L Delgado, Dhizarah Matus de la Parra-Pellot, Diana Nichols-Vinuez. Psychosis and severe rhabdomyolysis associated with synthetic cannabinoid use: A case report. Clinical schizophrenia & related psychoses. vol 8. issue 4. 2015-10-19. PMID:23518784. |
synthetic cannabinoid (sc) or "spice" refers to a variety of herbal/chemical mixtures, which mimic the effects of marijuana. |
2015-10-19 |
2023-08-12 |
Not clear |
Jennifer Johnston, Nicholas Lintzeris, David J Allsop, Anastasia Suraev, Jessica Booth, Dean S Carson, David Helliwell, Adam Winstock, Iain S McGrego. Lithium carbonate in the management of cannabis withdrawal: a randomized placebo-controlled trial in an inpatient setting. Psychopharmacology. vol 231. issue 24. 2015-10-13. PMID:24880749. |
preclinical studies suggest that lithium carbonate (lithium) can reduce precipitated cannabinoid withdrawal in rats by stimulating release of the neuropeptide oxytocin, while two open-label studies indicate lithium may ameliorate cannabis withdrawal symptoms in humans. |
2015-10-13 |
2023-08-13 |
rat |
Jessica B Hancock-Allen, Lisa Barker, Michael VanDyke, Dawn B Holme. Notes from the Field: Death Following Ingestion of an Edible Marijuana Product--Colorado, March 2014. MMWR. Morbidity and mortality weekly report. vol 64. issue 28. 2015-10-01. PMID:26203632. |
the only confirmed findings were cannabinoids (7.2 ng/ml delta-9 tetrahydrocannabinol [thc] and 49 ng/ml delta-9 carboxy-thc, an inactive marijuana metabolite). |
2015-10-01 |
2023-08-13 |
Not clear |
Joseph J Palamar, Patricia Acost. Synthetic cannabinoid use in a nationally representative sample of US high school seniors. Drug and alcohol dependence. vol 149. 2015-09-30. PMID:25736618. |
synthetic cannabinoids are marketed as "legal highs" and have similar effects to cannabis (marijuana). |
2015-09-30 |
2023-08-13 |
Not clear |
Sattar Ostadhadi, Mahdieh Rahmatollahi, Ahmad-Reza Dehpour, Reza Rahimia. Therapeutic potential of cannabinoids in counteracting chemotherapy-induced adverse effects: an exploratory review. Phytotherapy research : PTR. vol 29. issue 3. 2015-09-29. PMID:25504799. |
cannabinoids (the active constituents of cannabis sativa) and their derivatives have got intense attention during recent years because of their extensive pharmacological properties. |
2015-09-29 |
2023-08-13 |
Not clear |
Sébastien Anizan, Mateus M Bergamaschi, Allan J Barnes, Garry Milman, Nathalie Desrosiers, Dayong Lee, David A Gorelick, Marilyn A Huesti. Impact of oral fluid collection device on cannabinoid stability following smoked cannabis. Drug testing and analysis. vol 7. issue 2. 2015-09-24. PMID:24995604. |
impact of oral fluid collection device on cannabinoid stability following smoked cannabis. |
2015-09-24 |
2023-08-13 |
human |
Mohamed M Radwan, Mahmoud A ElSohly, Abir T El-Alfy, Safwat A Ahmed, Desmond Slade, Afeef S Husni, Susan P Manly, Lisa Wilson, Suzanne Seale, Stephen J Cutler, Samir A Ros. Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa. Journal of natural products. vol 78. issue 6. 2015-09-15. PMID:26000707. |
isolation and pharmacological evaluation of minor cannabinoids from high-potency cannabis sativa. |
2015-09-15 |
2023-08-13 |
mouse |
Mohamed M Radwan, Mahmoud A ElSohly, Abir T El-Alfy, Safwat A Ahmed, Desmond Slade, Afeef S Husni, Susan P Manly, Lisa Wilson, Suzanne Seale, Stephen J Cutler, Samir A Ros. Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa. Journal of natural products. vol 78. issue 6. 2015-09-15. PMID:26000707. |
seven new naturally occurring hydroxylated cannabinoids (1-7), along with the known cannabiripsol (8), have been isolated from the aerial parts of high-potency cannabis sativa. |
2015-09-15 |
2023-08-13 |
mouse |
E Singer, J Judkins, N Salomonis, L Matlaf, P Soteropoulos, S McAllister, L Sorocean. Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma. Cell death & disease. vol 6. 2015-09-11. PMID:25590811. |
in this study, we investigated mechanisms underlying gsc response and resistance to cannabidiol (cbd), a non-toxic, non-psychoactive cannabinoid and redox modulator. |
2015-09-11 |
2023-08-13 |
mouse |
Selim R Benbadis, Juan Sanchez-Ramos, Ali Bozorg, Melissa Giarratano, Kavita Kalidas, Lara Katzin, Derrick Robertson, Tuan Vu, Amanda Smith, Theresa Zesiewic. Medical marijuana in neurology. Expert review of neurotherapeutics. vol 14. issue 12. 2015-09-01. PMID:25427150. |
constituents of the cannabis plant, cannabinoids, may be of therapeutic value in neurologic diseases. |
2015-09-01 |
2023-08-13 |
Not clear |
Selim R Benbadis, Juan Sanchez-Ramos, Ali Bozorg, Melissa Giarratano, Kavita Kalidas, Lara Katzin, Derrick Robertson, Tuan Vu, Amanda Smith, Theresa Zesiewic. Medical marijuana in neurology. Expert review of neurotherapeutics. vol 14. issue 12. 2015-09-01. PMID:25427150. |
the most abundant cannabinoids are Δ(9)-tetrahydrocannabinol, which possesses psychoactive properties, and cannabidiol, which has no intrinsic psychoactive effects, but exhibits neuroprotective properties in preclinical studies. |
2015-09-01 |
2023-08-13 |
Not clear |
Ester Aso, Alexandre Sánchez-Pla, Esteban Vegas-Lozano, Rafael Maldonado, Isidro Ferre. Cannabis-based medicine reduces multiple pathological processes in AβPP/PS1 mice. Journal of Alzheimer's disease : JAD. vol 43. issue 3. 2015-08-21. PMID:25125475. |
the present study supports this hypothesis demonstrating that delta-9-tetrahydrocannabinol (thc) or cannabidiol (cbd) botanical extracts, as well as the combination of both natural cannabinoids, which are the components of an already approved cannabis-based medicine, preserved memory in aβpp/ps1 transgenic mice when chronically administered during the early symptomatic stage. |
2015-08-21 |
2023-08-13 |
mouse |
Venkatesh L Hegde, Udai P Singh, Prakash S Nagarkatti, Mitzi Nagarkatt. Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor γ in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo. Journal of immunology (Baltimore, Md. : 1950). vol 194. issue 11. 2015-08-17. PMID:25917103. |
cannabidiol (cbd) is a natural nonpsychotropic cannabinoid from marijuana (cannabis sativa) with anti-epileptic and anti-inflammatory properties. |
2015-08-17 |
2023-08-13 |
mouse |
Gregory T Carter, Simone P Javaher, Michael Hv Nguyen, Sharon Garret, Beatriz H Carlin. Re-branding cannabis: the next generation of chronic pain medicine? Pain management. vol 5. issue 1. 2015-08-12. PMID:25537695. |
cannabis and its active ingredients, cannabinoids, are a much safer therapeutic option. |
2015-08-12 |
2023-08-13 |
Not clear |