| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anas Khan, Brittany Richardson, Nicole Roeder, John Hamilton, Matthew Marion, Nathan Fearby, Olivia White, Yuji Owada, Yoshiteru Kagawa, Panayotis K Thano. The role of fatty acid-binding protein 5 and 7 on locomotor, anxiety and social behavior: Interaction with NMDA signaling. Neuroscience letters. 2024-06-08. PMID:38851448. |
results from the nmda autoradiography revealed [3h] mk-801 binding to be significantly increased within sub-regions of the striatum in fabp7-/- compared with control. |
2024-06-08 |
2024-06-11 |
mouse |
| David Kolar, Lenka Kleteckova, Katerina Skalova, Hana Brozka, Martin Kalous, Karel Vale. Glycolytic and Krebs cycle enzymes activity in rat prefrontal cortex, hippocampus, and striatum after single and repeated NMDA inhibition by MK-801. Neurotoxicology. 2022-02-27. PMID:35219782. |
glycolytic and krebs cycle enzymes activity in rat prefrontal cortex, hippocampus, and striatum after single and repeated nmda inhibition by mk-801. |
2022-02-27 |
2023-08-13 |
rat |
| Andrew W Hume, R Andrew Taske. Endothelin-1-Induced Ischemic Damage and Functional Impairment Is Mediated Primarily by NR2B-Containing NMDA Receptors. Neurotoxicity research. vol 37. issue 2. 2020-11-12. PMID:31797304. |
to test the hypothesis that nmda receptors, and particularly those containing the nr2b subunit, are involved in et-1-mediated excitotoxicity and functional impairment, male cd1 rats (n = 32) were pre-treated with either the non-competitive nmda antagonist mk-801 or the nr2b-selective antagonist ro25-6981 (or vehicle) prior to unilateral microinjections of endothelin-1 into the somatosensory cortex and striatum. |
2020-11-12 |
2023-08-13 |
rat |
| A. C. Foster, C. L. Willis, R. Tridget. Protection Against N-methyl-D-aspartate Receptor-Mediated Neuronal Degeneration In Rat Brain by 7-chlorokynurenate and 3-amino-1-hydroxypyrrolid-2-one, Antagonists at The Allosteric Site for Glycine. The European journal of neuroscience. vol 2. issue 3. 2019-11-20. PMID:12106053. |
the time course of protective effects of 7-cl kyna and ha-966 in the striatum was similar to that previously observed with the uncompetitive nmda receptor antagonist mk-801, indicating that activation of the glycine site contributes to the delayed degeneration of neurons which occurs over the first 5 h following quinolinate injection. |
2019-11-20 |
2023-08-12 |
rat |
| Alana Pimentel Moura, Belisa Parmeggiani, Juciano Gasparotto, Mateus Grings, Gabriela Miranda Fernandez Cardoso, Bianca Seminotti, José Cláudio Fonseca Moreira, Daniel Pens Gelain, Moacir Wajner, Guilhian Leipnit. Glycine Administration Alters MAPK Signaling Pathways and Causes Neuronal Damage in Rat Brain: Putative Mechanisms Involved in the Neurological Dysfunction in Nonketotic Hyperglycinemia. Molecular neurobiology. vol 55. issue 1. 2018-12-11. PMID:28050793. |
moreover, gly-induced decrease of p38 phosphorylation in striatum was attenuated by n-methyl-d-aspartate receptor antagonist mk-801. |
2018-12-11 |
2023-08-13 |
rat |
| Laura Osorio-Rico, Juana Villeda-Hernández, Abel Santamaría, Mina Königsberg, Sonia Galván-Arzat. The N-Methyl-d-Aspartate Receptor Antagonist MK-801 Prevents Thallium-Induced Behavioral and Biochemical Alterations in the Rat Brain. International journal of toxicology. vol 34. issue 6. 2016-09-19. PMID:26350230. |
mk-801 attenuated the tl(+)-induced hyperactivity and lipid peroxidation in the rat striatum, hippocampus and midbrain, and produced mild effects on other end points. |
2016-09-19 |
2023-08-13 |
rat |
| Mateus Struecker da Rosa, César Augusto João Ribeiro, Bianca Seminotti, Rafael Teixeira Ribeiro, Alexandre Umpierrez Amaral, Daniella de Moura Coelho, Francine Hehn de Oliveira, Guilhian Leipnitz, Moacir Wajne. In vivo intracerebral administration of L-2-hydroxyglutaric acid provokes oxidative stress and histopathological alterations in striatum and cerebellum of adolescent rats. Free radical biology & medicine. vol 83. 2016-03-14. PMID:25701435. |
it was also found that the melatonin, ascorbic acid plus α-tocopherol, and creatine totally prevented most of these effects, whereas n-acetylcysteine, the noncompetitive glutamate nmda antagonist mk-801, and the nitric oxide synthase inhibitor l-name were not able to normalize the redox alterations elicited by l-2-hg in striatum. |
2016-03-14 |
2023-08-13 |
rat |
| D Mahmood, K K Pillai, R Khanam, K Jahan, D Goswami, M Akhta. The Effect of Subchronic Dosing of Ciproxifan and Clobenpropit on Dopamine and Histamine Levels in Rats. Journal of experimental neuroscience. vol 9. 2015-09-18. PMID:26379444. |
mk-801 raised dopamine levels in the striatum, which was reduced in rats pretreated with cpx and cbp. |
2015-09-18 |
2023-08-13 |
rat |
| P Medeiros, M B Viana, R C Barbosa-Silva, L C Tonelli, L Melo-Thoma. Glutamatergic neurotransmission in the inferior colliculus influences intrastriatal haloperidol-induced catalepsy. Behavioural brain research. vol 268. 2014-12-16. PMID:24667361. |
male wistar rats received bilateral intracollicular microinjections of the glutamate receptor agonist nmda (10 or 20 nmol/0.5 μl), the nmda receptor antagonists mk-801 (15 or 30 nmol/0.5 μl) or physiological saline (0.5 μl), followed by bilateral microinjections of haloperidol (10 μg/0.5 μl) or vehicle (0.5 μl) into the dorso-rostral or ventro-rostral striatum. |
2014-12-16 |
2023-08-12 |
rat |
| P Medeiros, M B Viana, R C Barbosa-Silva, L C Tonelli, L Melo-Thoma. Glutamatergic neurotransmission in the inferior colliculus influences intrastriatal haloperidol-induced catalepsy. Behavioural brain research. vol 268. 2014-12-16. PMID:24667361. |
the microinjection of haloperidol into the ventro-rostral striatum induced catalepsy, counteracted by previous administration of mk-801 into the ic. |
2014-12-16 |
2023-08-12 |
rat |
| Alana Pimentel Moura, Mateus Grings, Belisa Dos Santos Parmeggiani, Gustavo Flora Marcowich, Anelise Miotti Tonin, Carolina Maso Viegas, Angela Zanatta, César Augusto João Ribeiro, Moacir Wajner, Guilhian Leipnit. Glycine intracerebroventricular administration disrupts mitochondrial energy homeostasis in cerebral cortex and striatum of young rats. Neurotoxicity research. vol 24. issue 4. 2014-04-29. PMID:23640702. |
finally, the antioxidants n-acetylcysteine and creatine, and the nmda receptor antagonist mk-801 attenuated or fully prevented the inhibitory effects of gly on creatine kinase and respiratory complexes in cerebral cortex and striatum. |
2014-04-29 |
2023-08-12 |
rat |
| Lilian R F Faro, Brenda V Ferreira Nunes, Miguel Alfonso, Vania M Ferreira, Rafael Durá. Role of glutamate receptors and nitric oxide on the effects of glufosinate ammonium, an organophosphate pesticide, on in vivo dopamine release in rat striatum. Toxicology. vol 311. issue 3. 2013-11-04. PMID:23810826. |
for this, we used antagonists of nmda (mk-801 and ap5) or ampa/kainate (cnqx) receptors, or nitric oxide synthase (nos) inhibitors (l-name and 7-ni), to study the effects of gla on release of dopamine from rat striatum. |
2013-11-04 |
2023-08-12 |
rat |
| Nobuyuki Maruoka, Tetsuhito Murata, Naoto Omata, Hironori Mitsuya, Yasushi Kiyono, Hidehiko Okazawa, Yuji Wad. Region-specific causal mechanism in the effects of ammonia on cerebral glucose metabolism in the rat brain. Journal of neural transmission (Vienna, Austria : 1996). vol 120. issue 3. 2013-08-12. PMID:23124771. |
pre-treatment with (+)-5-methyl-10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate (mk-801), a n-methyl-d-aspartate (nmda) receptor antagonist, significantly attenuated these changes induced by ammonia in cerebellum, but not in cerebral cortex or striatum. |
2013-08-12 |
2023-08-12 |
rat |
| J Liu, C F Wu, W Liu, H L Zhang, C L L. Involvement of the corticostriatal glutamatergic pathway in ethanol-induced ascorbic acid release in rat striatum. Addiction biology. vol 4. issue 3. 2012-10-02. PMID:20575794. |
the basal level of aa in striatum could only be reduced by high doses of mk-801, but not by low doses of mk-801, amantadine or decortication. |
2012-10-02 |
2023-08-12 |
rat |
| T Araki, H Kato, K Shuto, T Fujiwara, Y Itoyam. Different age-related changes in NMDA and glycine receptors in the rat brain. Environmental toxicology and pharmacology. vol 1. issue 2. 2012-10-02. PMID:21781669. |
in immature rats, [(3)h]mk-801 binding showed a significant decline only in the nucleus accumbens, whereas [(3)h]glycine binding exhibited a significant increase in the frontal cortex, parietal cortex, striatum and thalamus as compared with young rats. |
2012-10-02 |
2023-08-12 |
rat |
| Chun-Li Duan, Xiao-Hong Sun, Man Ji, Hui Yan. Effects of glutamate and MK-801 on the metabolism of dopamine in the striatum of normal and parkinsonian rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719139. |
effects of glutamate and mk-801 on the metabolism of dopamine in the striatum of normal and parkinsonian rats. |
2012-06-28 |
2023-08-12 |
rat |
| Chun-Li Duan, Xiao-Hong Sun, Man Ji, Hui Yan. Effects of glutamate and MK-801 on the metabolism of dopamine in the striatum of normal and parkinsonian rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719139. |
the direct effects of glutamate and dizocilpine maleate (mk-801, non-competitive n-methyl-d-aspartate glutamate receptor antagonist) on the metabolism of dopamine were investigated in the striatum of normal and parkinsonian rats. |
2012-06-28 |
2023-08-12 |
rat |
| Chun-Li Duan, Xiao-Hong Sun, Man Ji, Hui Yan. Effects of glutamate and MK-801 on the metabolism of dopamine in the striatum of normal and parkinsonian rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719139. |
l-dopa, l-glutamic acid and mk-801 were administered in the striatum locally by microdialysis. |
2012-06-28 |
2023-08-12 |
rat |
| Chun-Li Duan, Xiao-Hong Sun, Man Ji, Hui Yan. Effects of glutamate and MK-801 on the metabolism of dopamine in the striatum of normal and parkinsonian rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719139. |
mk-801 increased the concentrations of dopac and hva in the striatum of normal rats but not parkinsonian rats. |
2012-06-28 |
2023-08-12 |
rat |
| Chun-Li Duan, Xiao-Hong Sun, Man Ji, Hui Yan. Effects of glutamate and MK-801 on the metabolism of dopamine in the striatum of normal and parkinsonian rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719139. |
mk-801 prevented the l-glutamic acid-induced decrease of dopac and hva in the striatum of normal rats. |
2012-06-28 |
2023-08-12 |
rat |