All Relations between trem2 and microglial cell
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Kazuya Takahashi, Christian D P Rochford, Harald Neuman. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. The Journal of experimental medicine. vol 201. issue 4. 2005-04-11. PMID:15728241. | knockdown of trem2 in microglia inhibited phagocytosis of apoptotic neurons and increased gene transcription of tumor necrosis factor alpha and nitric oxide synthase-2, whereas overexpression of trem2 increased phagocytosis and decreased microglial proinflammatory responses. | 2005-04-11 | 2023-08-12 | Not clear |
| Giuseppina Sessa, Paola Podini, Margherita Mariani, Alessandra Meroni, Roberto Spreafico, Francesco Sinigaglia, Marco Colonna, Paola Panina, Jacopo Meldoles. Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548205. | in living human microglia chme-5 and glioblastoma t98g cells, activation of trem2 by its specific antibody induced [ca2+]i responses, documenting its surface expression and functioning. | 2005-03-01 | 2023-08-12 | mouse |