| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M G von Herrath, T Dyrberg, M B Oldston. Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice. The Journal of clinical investigation. vol 98. issue 6. 1996-11-25. PMID:8823297. |
thus, insulin therapy is effective in preventing progression to overt iddm in prediabetic tg mice with ongoing islet infiltration. |
1996-11-25 |
2023-08-12 |
mouse |
| L Böhlen, R Bienz, M Doser, M Papiri, S Shaw, W Riesen, P Weidman. Metabolic neutrality of perindopril: focus on insulin sensitivity in overweight patients with essential hypertension. Journal of cardiovascular pharmacology. vol 27. issue 6. 1996-11-21. PMID:8761842. |
moreover, no significant changes were apparent in fasting plasma insulin and glucose, the areas under the glucose and insulin curves, the glucose disappearance rates, serum total triglycerides (tg), or cholesterol or lipoprotein cholesterol fractions between run-in and active treatment phases in the perindopril or the placebo group, respectively. |
1996-11-21 |
2023-08-12 |
human |
| N Ravaja, L Keltikangas-Järvinen, P Keskivaar. Type A factors as predictors of changes in the metabolic syndrome precursors in adolescents and young adults--a 3-year follow-up study. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. vol 15. issue 1. 1996-10-24. PMID:8788537. |
physiological parameters studied were serum insulin, high-density and low-density lipoprotein cholesterol, triglycerides (tg), systolic and diastolic blood pressure, body-mass index (bmi), subscapular skinfold thickness (ssf), and centrality index. |
1996-10-24 |
2023-08-12 |
Not clear |
| N Ravaja, L Keltikangas-Järvinen, P Keskivaar. Type A factors as predictors of changes in the metabolic syndrome precursors in adolescents and young adults--a 3-year follow-up study. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. vol 15. issue 1. 1996-10-24. PMID:8788537. |
among the type a factors in boys and men, high baseline aggression predicted an increase in the individual parameters of metabolic syndrome (i.e., insulin, tg, ssf, and bmi) as well as a global aggravation of the cluster of metabolic parameters. |
1996-10-24 |
2023-08-12 |
Not clear |
| G F Lewis, G Steine. Acute effects of insulin in the control of VLDL production in humans. Implications for the insulin-resistant state. Diabetes care. vol 19. issue 4. 1996-10-11. PMID:8729170. |
we found a rapid suppression of plasma free fatty acid (ffa) levels in response to insulin and a consistent 50-60% insulin-induced suppression of both vldl tg and vldl apolipoprotein (apo) b in lean insulin-sensitive individuals. |
1996-10-11 |
2023-08-12 |
rat |
| G F Lewis, G Steine. Acute effects of insulin in the control of VLDL production in humans. Implications for the insulin-resistant state. Diabetes care. vol 19. issue 4. 1996-10-11. PMID:8729170. |
when the insulin-induced suppression of plasma ffa levels was prevented during hyperinsulinemia, vldl tg production was still inhibited, although to a lesser extent than with insulin alone. |
1996-10-11 |
2023-08-12 |
rat |
| F Uddin, A K Mia. Lipid profile and its relation to fasting insulin level in non-insulin dependent diabetes mellitus (NIDDM). Bangladesh Medical Research Council bulletin. vol 21. issue 2. 1996-10-10. PMID:8815864. |
total cholesterol, ldl-c, ldl/hdl ratio, tg (p always < 0.001) and fasting serum insulin (p = 0.033) were significantly higher and hdl-c was significantly lower (p = 0.001) in niddm than control subjects. |
1996-10-10 |
2023-08-12 |
human |
| R P Naoumova, M H Cummings, G F Watts, N B Rendell, G W Taylor, P H Sönksen, G R Thompso. Acute hyperinsulinaemia decreases cholesterol synthesis less in subjects with non-insulin-dependent diabetes mellitus than in non-diabetic subjects. European journal of clinical investigation. vol 26. issue 4. 1996-09-20. PMID:8732493. |
to investigate the effect of insulin on cholesterol synthesis in vivo we measured plasma mevalonic acid (mva) concentrations using gas chromatography-mass spectrometry in six non-obese patients with non-insulin-dependent diabetes mellitus (niddm) [four men, two women; age 57.5 +/- 2.2 years (mean +/- sem); glycated haemoglobin (hba1) 8.5 +/- 0.5%; total cholesterol (tc) 5.7 +/- 0.5 mmol l-1, triglyceride (tg) 3.8 +/- 0.9 mmol l-1] and six non-diabetic, sex- and age-matched control subjects (age 55.7 +/- 2.8 years; hba1 6.5 +/- 0.1%; tc 5.4 +/- 0.3 mmol l-1, tg 1.2 +/- 0.1 mmol l-1). |
1996-09-20 |
2023-08-12 |
human |
| L Yamamoto-Kimura, J Zamora-González, S Huerta-Alvarado, A Fajardo-Gutiérrez, G Cardoso-Saldaña, C Posadas-Romer. High blood pressure and cardiovascular risk factors in an adult population of Mexico City. Characteristics of the studied population. Archives of medical research. vol 27. issue 2. 1996-09-04. PMID:8696067. |
the following measurements were registered: blood pressure, body mass index (bmi), waist-hip ratio (whr), total cholesterol (tc), triglycerides (tg), high density lipoproteins (hdl-c) and low density lipoproteins (ldl-c), lipoprotein (a) (lp(a)), glucose and insulin. |
1996-09-04 |
2023-08-12 |
human |
| M Couce, L A Kane, T D O'Brien, J Charlesworth, W Soeller, J McNeish, D Kreutter, P Roche, P C Butle. Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction. Diabetes. vol 45. issue 8. 1996-08-28. PMID:8690157. |
in the present study, we sought to test the hypothesis that pharmacological induction of insulin resistance in a mouse transgenic (tg) for human iapp would induce islet amyloid and beta-cell dysfunction. |
1996-08-28 |
2023-08-12 |
mouse |
| M Couce, L A Kane, T D O'Brien, J Charlesworth, W Soeller, J McNeish, D Kreutter, P Roche, P C Butle. Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction. Diabetes. vol 45. issue 8. 1996-08-28. PMID:8690157. |
treatment with dex/gh caused hyperglycemia (7.3 +/- 0.4 vs. 5.2 +/- 0.1 mmol/l, tg vs. n-tg, p < 0.001) associated with a decreased plasma insulin concentration (595 +/- 51 vs. 996 +/- 100 pmol/l, tg vs. n-tg, p < 0.05) in tg versus control mice. |
1996-08-28 |
2023-08-12 |
mouse |
| E Bergström, O Hernell, L A Persson, B Vessb. Insulin resistance syndrome in adolescents. Metabolism: clinical and experimental. vol 45. issue 7. 1996-08-28. PMID:8692030. |
to explore whether the so-called insulin resistance syndrome can be identified in adolescents, serum insulin level was measured in 842 healthy swedish adolescents (462 boys and 380 girls) and the values were related to current serum lipoprotein and apolipoprotein values (triglyceride [tg], total cholesterol [tc], high-density lipoprotein cholesterol [hdl-c), low-density lipoprotein cholesterol [ldl-c], apolipoprotein [apo] a-i, apo b, and lipoprotein(a)), blood pressure (bp), and anthropometric measurements and previous physical growth. |
1996-08-28 |
2023-08-12 |
Not clear |
| E Bergström, O Hernell, L A Persson, B Vessb. Insulin resistance syndrome in adolescents. Metabolism: clinical and experimental. vol 45. issue 7. 1996-08-28. PMID:8692030. |
controlling for age, serum insulin correlated positively with bmi (r = .36 and .25 in boys and girls, respectively), tg (r = .32 and .14), ldl-c (r = .17 and .24), and apob (r = .23 and .23) and negatively with hdl-c (r = -.13 and -.21). |
1996-08-28 |
2023-08-12 |
Not clear |
| E Bergström, O Hernell, L A Persson, B Vessb. Insulin resistance syndrome in adolescents. Metabolism: clinical and experimental. vol 45. issue 7. 1996-08-28. PMID:8692030. |
high serum insulin, tg, ldl-c, and bp and low hdl-c clustered in adolescents with high bmi. |
1996-08-28 |
2023-08-12 |
Not clear |
| G Steiner, G F Lewi. Hyperinsulinemia and triglyceride-rich lipoproteins. Diabetes. vol 45 Suppl 3. 1996-08-15. PMID:8674884. |
the overall effect of hyperinsulinemia on vldl production is postulated to reflect both the effect of insulin on apolipoprotein b production and the hepatic synthesis of tg from either plasma ffas or newly made fatty acids. |
1996-08-15 |
2023-08-12 |
Not clear |
| C Y Jeng, W H Sheu, M M Fuh, S M Shieh, Y D Chen, G M Reave. Gemfibrozil treatment of endogenous hypertriglyceridemia: effect on insulin-mediated glucose disposal and plasma insulin concentrations. The Journal of clinical endocrinology and metabolism. vol 81. issue 7. 1996-08-15. PMID:8675576. |
thus, marked decreases in both plasma tg and free fatty acid concentrations seen in association with gemfibrozil neither enhanced insulin-mediated glucose disposal nor lowered ambient plasma insulin concentrations in patients with endogenous hypertriglyceridemia. |
1996-08-15 |
2023-08-12 |
Not clear |
| T Kazumi, T Hirano, H Odaka, T Ebara, N Amano, T Hozumi, Y Ishida, G Yoshin. VLDL triglyceride kinetics in Wistar fatty rats, an animal model of NIDDM: effects of dietary fructose alone or in combination with pioglitazone. Diabetes. vol 45. issue 6. 1996-07-09. PMID:8635657. |
although feeding fructose into fatty rats did not change plasma glucose and insulin levels, it produced a twofold increase in tg levels (8.74 +/- 1.15 mmol/l). |
1996-07-09 |
2023-08-12 |
rat |
| B D Mitchell, C M Kammerer, M C Mahaney, J Blangero, A G Comuzzie, L D Atwood, S M Haffner, M P Stern, J W MacClue. Genetic analysis of the IRS. Pleiotropic effects of genes influencing insulin levels on lipoprotein and obesity measures. Arteriosclerosis, thrombosis, and vascular biology. vol 16. issue 2. 1996-06-18. PMID:8620344. |
since insulin resistance is at least partially genetically determined, we hypothesized that genes influencing insulin resistance would have pleiotropic effects on a number of other traits, including triglyceride (tg) and hdl cholesterol levels, body mass index (bmi) and body fat distribution, and blood pressure levels. |
1996-06-18 |
2023-08-12 |
Not clear |
| L Keltikangas-Jarvinen, N Ravaja, K Raikkonen, H Lyytine. Insulin resistance syndrome and autonomically mediated physiological responses to experimentally induced mental stress in adolescent boys. Metabolism: clinical and experimental. vol 45. issue 5. 1996-06-18. PMID:8622606. |
irs parameters measured were serum insulin, high-density lipoprotein (hdl) cholesterol, serum triglyceride (tg), systolic blood pressure (sbp), subscapular skinfold (ssf), and subscapular to triceps skinfold ratio (str). |
1996-06-18 |
2023-08-12 |
Not clear |
| B Chowdhury, H Lantz, L Sjostro. Computed tomography-determined body composition in relation to cardiovascular risk factors in Indian and matched Swedish males. Metabolism: clinical and experimental. vol 45. issue 5. 1996-06-18. PMID:8622609. |
fasting glucose, insulin, and triglycerides (tg) were higher in indians than in swedes. |
1996-06-18 |
2023-08-12 |
Not clear |