| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Maheux, S Azhar, P A Kern, Y D Chen, G M Reuve. Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase. Diabetologia. vol 40. issue 7. 1997-10-15. PMID:9243108. |
the relationship between insulin-mediated glucose disposal and fasting insulin and triglyceride (tg) concentrations, plasma post-heparin lipoprotein lipase (ph-lpl) activity and mass, and adipose tissue lpl activity, mass, and mrna content was defined in 19 non-diabetic men. |
1997-10-15 |
2023-08-12 |
Not clear |
| P Maheux, S Azhar, P A Kern, Y D Chen, G M Reuve. Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase. Diabetologia. vol 40. issue 7. 1997-10-15. PMID:9243108. |
insulin-mediated glucose uptake [as assessed by determining the steady-state plasma glucose (sspg) concentration during a continuous infusion of somatostatin, insulin, and glucose] was significantly correlated with fasting tg concentration (r = 0.54, p < 0.02), plasma ph-lpl activity (r = -0.52, p < 0.03) and mass (r = -0.49, p < 0.03), and adipose tissue lpl mrna content (r = -0.68, p < 0.001). |
1997-10-15 |
2023-08-12 |
Not clear |
| P Maheux, S Azhar, P A Kern, Y D Chen, G M Reuve. Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase. Diabetologia. vol 40. issue 7. 1997-10-15. PMID:9243108. |
using in vivo and molecular biology techniques, these data demonstrate that the more insulin resistant an individual, the lower the level of plasma ph-lpl activity and mass, and the higher the plasma tg concentration. |
1997-10-15 |
2023-08-12 |
Not clear |
| P Maheux, S Azhar, P A Kern, Y D Chen, G M Reuve. Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase. Diabetologia. vol 40. issue 7. 1997-10-15. PMID:9243108. |
since lower concentrations of adipose tissue mrna were also directly correlated with plasma ph-lpl mass (r = 0.57, p < 0.01), and inversely with plasma tg concentration (r = -0.68, p < 0.001) as well as sspg (r = -0.68, p < 0.001), it can be postulated that the relationship between insulin resistance and lpl activity and plasma tg concentration is associated with the inability of insulin to stimulate the transcription or to increase the intracellular mrna stability of adipose tissue lpl in insulin resistant individuals. |
1997-10-15 |
2023-08-12 |
Not clear |
| O T Raitakari, S Taimela, K V Porkka, R Telama, I Välimäki, H K Akerblom, J S Viikar. Associations between physical activity and risk factors for coronary heart disease: the Cardiovascular Risk in Young Finns Study. Medicine and science in sports and exercise. vol 29. issue 8. 1997-10-15. PMID:9268963. |
the results show that a high level of physical activity was associated with high serum high density lipoprotein cholesterol (hdl-c) and hdl2-c concentrations, and low levels of serum triglycerides (tg), apolipoprotein b and insulin in males. |
1997-10-15 |
2023-08-12 |
Not clear |
| D R Jensen, I R Schlaepfer, C L Morin, D S Pennington, T Marcell, S M Ammon, A Gutierrez-Hartmann, R H Ecke. Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase. The American journal of physiology. vol 273. issue 2 Pt 2. 1997-09-25. PMID:9277555. |
overall, when tg mice were fed either a hc or hf diet for 13 wk, plasma triglycerides (p < 0.001) and free fatty acids (p < 0.001) were decreased, whereas plasma glucose (p = 0.01) and insulin (p = 0.05) were increased compared with ntg mice. |
1997-09-25 |
2023-08-12 |
mouse |
| H Knobler, Y Weiss, M Peled, Y Grone. Impaired glucose-induced insulin response in transgenic mice overexpressing the L-phosphofructokinase gene. Diabetes. vol 46. issue 9. 1997-09-25. PMID:9287040. |
in this study, we evaluated insulin secretion in transgenic (tg) mice overexpressing the liver-type subunit of phosphofructokinase (pfkl). |
1997-09-25 |
2023-08-12 |
mouse |
| K C Shih, C F Kwok, C M Hwu, L C Hsiao, S H Li, Y F Liu, L T H. Acipimox attenuates hypertriglyceridemia in dyslipidemic noninsulin dependent diabetes mellitus patients without perturbation of insulin sensitivity and glycemic control. Diabetes research and clinical practice. vol 36. issue 2. 1997-08-25. PMID:9229195. |
taken together, our data suggest that acipimox significantly lowered tg without perturbation of insulin sensitivity in hypertriglyceridemic niddm patients. |
1997-08-25 |
2023-08-12 |
Not clear |
| K L Edwards, B Newman, E Mayer, J V Selby, R M Krauss, M A Austi. Heritability of factors of the insulin resistance syndrome in women twins. Genetic epidemiology. vol 14. issue 3. 1997-07-24. PMID:9181354. |
the insulin resistance syndrome (irs) is characterized by a combination of interrelated coronary heart disease (chd) risk factors, including low high-density lipoprotein cholesterol (hdl-c) levels, obesity and increases in triglyceride (tg), blood pressure, small low-density lipoprotein particles (ldl), and both fasting and postload plasma insulin and glucose. |
1997-07-24 |
2023-08-12 |
Not clear |
| E Pagano, A Siani, P Pauciullo, C Lirato, R Iacone, A Sacchi, P Strazzull. Effect of dietary versus pharmacological correction of hypertriglyceridemia on red blood cell membrane sodium/lithium countertransport activity. Life sciences. vol 60. issue 26. 1997-07-21. PMID:9199483. |
in conclusion, these results indicate that the decrease in na/li ct associated with both dietary and drug treatment of hypertriglyceridemia is to be traced to a direct effect of plasma tg concentration on this transport system (probably as a result of modification in the membrane lipid environment) rather than to changes in plasma insulin levels or insulin resistance. |
1997-07-21 |
2023-08-12 |
Not clear |
| A E Sumner, H Kushner, T N Tulenko, B Falkner, J B Mars. The relationship in African-Americans of sex differences in insulin-mediated suppression of nonesterified fatty acids to sex differences in fasting triglyceride levels. Metabolism: clinical and experimental. vol 46. issue 4. 1997-05-08. PMID:9109843. |
an oral glucose tolerance test (ogtt) was performed with fasting tg levels and plasma insulin and nefa concentrations obtained at 0, 30, 60, and 120 minutes. |
1997-05-08 |
2023-08-12 |
Not clear |
| H K Struder, W Hollmann, P Platen, J Duperly, H G Fischer, K Webe. Alterations in plasma free tryptophan and large neutral amino acids do not affect perceived exertion and prolactin during 90 min of treadmill exercise. International journal of sports medicine. vol 17. issue 2. 1997-05-07. PMID:8833706. |
prl, insulin, glucose, ammonia, lactate, triglycerides (tg), free fatty acids (ffa) and amino acids were determined in each sample. |
1997-05-07 |
2023-08-12 |
Not clear |
| S T Dheen, K Rajkumar, L J Murph. Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice. Diabetologia. vol 39. issue 11. 1997-03-17. PMID:8932988. |
these observations prompted us to investigate the effects of glucose and insulin-like growth factor-i (igf-i) on insulin and glucagon release by isolated islets from tg and wt mice. |
1997-03-17 |
2023-08-12 |
mouse |
| S T Dheen, K Rajkumar, L J Murph. Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice. Diabetologia. vol 39. issue 11. 1997-03-17. PMID:8932988. |
under basal glucose conditions, islets from tg mice released significantly more insulin and less glucagon than islets from wt mice. |
1997-03-17 |
2023-08-12 |
mouse |
| S T Dheen, K Rajkumar, L J Murph. Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice. Diabetologia. vol 39. issue 11. 1997-03-17. PMID:8932988. |
a dose-dependent increase in insulin release was observed with increased glucose concentrations in both wt and tg mice. |
1997-03-17 |
2023-08-12 |
mouse |
| S T Dheen, K Rajkumar, L J Murph. Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice. Diabetologia. vol 39. issue 11. 1997-03-17. PMID:8932988. |
at all but the highest glucose concentration, islets from tg mice released significantly greater amounts of insulin than islets from wt mice. |
1997-03-17 |
2023-08-12 |
mouse |
| S T Dheen, K Rajkumar, L J Murph. Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice. Diabetologia. vol 39. issue 11. 1997-03-17. PMID:8932988. |
furthermore, an intrinsic defect in pancreatic islet insulin release is not responsible for the glucose intolerance in tg mice. |
1997-03-17 |
2023-08-12 |
mouse |
| J T Brozinick, S C McCoid, T H Reynolds, C M Wilson, R W Stevenson, S W Cushman, E M Gibb. Regulation of cell surface GLUT4 in skeletal muscle of transgenic mice. The Biochemical journal. vol 321 ( Pt 1). 1997-02-20. PMID:9003403. |
thus we have assessed cell surface glut4 by photolabelling with the membrane-impermeant reagent 2-n-[4-(1-azi-2,2,2-trifluoroethyl)benzoyl]-1, 3-bis(d-mannos-4-yloxy)-2-propylamine (atb-bmpa) and measured the corresponding glucose transport activity using 2-deoxyglucose in isolated extensor digitorum longus (edl) muscles from non-transgenic (ntg) and glut4 tg mice in the absence and presence of 13.3 nm (2000 mu units/ml) insulin, without or with hypoxia as a model of muscle contraction. |
1997-02-20 |
2023-08-12 |
mouse |
| J T Brozinick, S C McCoid, T H Reynolds, C M Wilson, R W Stevenson, S W Cushman, E M Gibb. Regulation of cell surface GLUT4 in skeletal muscle of transgenic mice. The Biochemical journal. vol 321 ( Pt 1). 1997-02-20. PMID:9003403. |
tg mice displayed elevated rates of glucose transport activity under basal and insulin-stimulated conditions, and in the presence of insulin plus hypoxia, compared with ntg mice. |
1997-02-20 |
2023-08-12 |
mouse |
| D Meirow, I Raz, O Yossepowitch, A Brzezinski, A Rosler, J G Schenker, E M Berr. Dyslipidaemia in polycystic ovarian syndrome: different groups, different aetiologies? Human reproduction (Oxford, England). vol 11. issue 9. 1997-02-18. PMID:8921052. |
pcos patients had higher fasting insulin concentrations, higher body mass indexes (bmi) and were hyperlipidaemic, with higher total cholesterol, low density lipoprotein (ldl) and triglyceride (tg) concentrations. |
1997-02-18 |
2023-08-12 |
human |