| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Carantoni, G Zuliani, G Bader, E Palmieri, S Volpato, A Passaro, T Imbastaro, A Mezzetti, R Felli. Low density lipoprotein cholesterol, lipoprotein(a), and apo(a) isoforms in the elderly: relationship to fasting insulin. Associazione Medica Sabin. Nutrition, metabolism, and cardiovascular diseases : NMCD. vol 9. issue 5. 2000-02-24. PMID:10656169. |
we investigated the relationship between plasma fasting insulin with total cholesterol (tc) and low density lipoprotein ldl cholesterol (ldl-c), triglycerides (tg), lipoprotein(a) [lp(a)] levels apolipoprotein (a) [apo (a)] isoforms in 100 free-living "healthy" octo-nonagenarians. |
2000-02-24 |
2023-08-12 |
Not clear |
| I E Royaux, K Suzuki, A Mori, R Katoh, L A Everett, L D Kohn, E D Gree. Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells. Endocrinology. vol 141. issue 2. 2000-02-10. PMID:10650967. |
using a cultured rat thyroid cell line (frtl-5), pds expression was found to be significantly induced by low concentrations of thyroglobulin (tg), but not by tsh, sodium iodide, or insulin. |
2000-02-10 |
2023-08-12 |
rat |
| Z W Man, T Hirashima, S Mori, K Kawan. Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model. Metabolism: clinical and experimental. vol 49. issue 1. 2000-02-02. PMID:10647073. |
with respect to the connection between triglyceride (tg) and non-insulin-dependent diabetes mellitus (niddm), previous reports have shown that tg accumulation in the liver and muscle is one of the causes of insulin resistance, and tg accumulation in pancreatic islets induces impairment of pancreatic beta-cell function. |
2000-02-02 |
2023-08-12 |
rat |
| Z W Man, T Hirashima, S Mori, K Kawan. Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model. Metabolism: clinical and experimental. vol 49. issue 1. 2000-02-02. PMID:10647073. |
in this experiment using otsuka long-evans tokushima fatty (oletf) rats developing niddm and long-evans tokushima otsuka (leto) rats as controls, sequential changes in body weight and tg content in tissue were measured and biochemical blood tests, an insulin euglycemic clamp test, and histopathologic examination of the pancreas and liver were performed. |
2000-02-02 |
2023-08-12 |
rat |
| Z W Man, T Hirashima, S Mori, K Kawan. Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model. Metabolism: clinical and experimental. vol 49. issue 1. 2000-02-02. PMID:10647073. |
as a result, several findings were more evident in the restricted group than in the satiated group: (1) reductions in body weight and intraabdominal fat weight, decreases in plasma tg, insulin, and glucose levels, a decrease in the tg secretion rate, and an increase in plasma lipoprotein lipase (lpl) activity, (2) decreases in the tg content in the liver, pancreas, and muscle, (3) improvement of the glucose infusion rate (gir), and (4) a marked reduction of tg accumulation in the liver and pancreatic islets on histopathologic examination. |
2000-02-02 |
2023-08-12 |
rat |
| Z W Man, T Hirashima, S Mori, K Kawan. Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model. Metabolism: clinical and experimental. vol 49. issue 1. 2000-02-02. PMID:10647073. |
these results indicate that the improved htg caused a reduction in tg accumulation in the liver and muscle, thereby improving insulin resistance. |
2000-02-02 |
2023-08-12 |
rat |
| T C Bryant, J D Rivera, M L Galyean, G C Duff, D M Hallford, T H Montgomer. Effects of dietary level of ruminally protected choline on performance and carcass characteristics of finishing beef steers and on growth and serum metabolites in lambs. Journal of animal science. vol 77. issue 11. 1999-12-21. PMID:10568457. |
serum triglycerides (tg) and cholesterol (clstrl) were measured in weekly blood samples, and intensive blood samples were collected on d 28 and 56 to evaluate serum insulin (ins), gh, and nefa. |
1999-12-21 |
2023-08-12 |
cattle |
| A Kahler, M Zimmermann, W Langhan. Suppression of hepatic fatty acid oxidation and food intake in men. Nutrition (Burbank, Los Angeles County, Calif.). vol 15. issue 11-12. 1999-12-10. PMID:10575655. |
plasma triacylglycerols (tg), free fatty acids (ffa), glucose, and insulin were not affected by eto. |
1999-12-10 |
2023-08-12 |
human |
| A Kahler, M Zimmermann, W Langhan. Suppression of hepatic fatty acid oxidation and food intake in men. Nutrition (Burbank, Los Angeles County, Calif.). vol 15. issue 11-12. 1999-12-10. PMID:10575655. |
plasma concentrations of tg, glucose, and insulin were not affected by eto. |
1999-12-10 |
2023-08-12 |
human |
| C J Glueck, J E Lang, T Tracy, L Sieve-Smith, P Wan. Contribution of fasting hyperinsulinemia to prediction of atherosclerotic cardiovascular disease status in 293 hyperlipidemic patients. Metabolism: clinical and experimental. vol 48. issue 11. 1999-12-10. PMID:10582554. |
fasting serum insulin of 20 microu/ml or higher was very common in women (59% to 100%) and men (67% to 88%) when hypertension, obesity, top-decile triglyceride (tg), and bottom-decile high-density lipoprotein cholesterol (hdlc) were concurrent in various combinations. |
1999-12-10 |
2023-08-12 |
human |
| C J Glueck, J E Lang, T Tracy, L Sieve-Smith, P Wan. Contribution of fasting hyperinsulinemia to prediction of atherosclerotic cardiovascular disease status in 293 hyperlipidemic patients. Metabolism: clinical and experimental. vol 48. issue 11. 1999-12-10. PMID:10582554. |
ascvd events (present or absent) were dependent variables in a stepwise logistic regression model with explanatory variables including age, gender, race, hypertension, cigarette smoking, ascvd in first-degree relatives at age 55 years or less, quetelet index, fasting serum insulin, a gender x insulin interaction term, anticardiolipin antibodies (aclas) igg and igm, total cholesterol to hdlc ratio, tg, lipoprotein(a) [lp(a)], and homocysteine. |
1999-12-10 |
2023-08-12 |
human |
| T Tanaka, Y Seino, K Fujieda, Y Igarashi, S Yokoya, K Tachibana, Y Ogaw. Pharmacokinetics and metabolic effects of high-dose growth hormone administration in healthy adult men. Endocrine journal. vol 46. issue 4. 1999-12-02. PMID:10580755. |
to evaluate pharmacokinetics of growth hormone (gh) and its effects on igf-i, glucose, insulin, nonesterified fatty acid (nefa) and triglyceride (tg), fifteen japanese healthy adult male volunteers (20-27 years old) were studied. |
1999-12-02 |
2023-08-12 |
human |
| K R Kulkarni, J H Markovitz, N C Nanda, J P Segres. Increased prevalence of smaller and denser LDL particles in Asian Indians. Arteriosclerosis, thrombosis, and vascular biology. vol 19. issue 11. 1999-11-30. PMID:10559021. |
furthermore, this increased prevalence of small, dense ldl type appears to be due to the increased triglycerides (tg) (r for ldl-rf versus tg=0.681, p<0.001), with fasting insulin being one of the important determinants of tg (r for tg versus fasting insulin=0.572, p<0.001). |
1999-11-30 |
2023-08-12 |
human |
| H Maegawa, M Hasegawa, S Sugai, T Obata, S Ugi, K Morino, K Egawa, T Fujita, T Sakamoto, Y Nishio, H Kojima, M Haneda, H Yasuda, R Kikkawa, A Kashiwag. Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance. The Journal of biological chemistry. vol 274. issue 42. 1999-11-19. PMID:10514516. |
plasma insulin levels in tg mice after 4 h fasting were 3 times greater with comparable blood glucose levels. |
1999-11-19 |
2023-08-12 |
mouse |
| R M O'Doherty, D L Lehman, S Télémaque-Potts, C B Newgar. Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia. Diabetes. vol 48. issue 10. 1999-10-19. PMID:10512368. |
adcmv-gkl-treated fasted rats exhibited no significant changes in circulating glucose, free fatty acids (ffas), lactate, beta-hydroxybutyrate, or insulin levels relative to controls, whereas triglyceride (tg) levels were slightly increased (53%). |
1999-10-19 |
2023-08-12 |
rat |
| R M O'Doherty, D L Lehman, S Télémaque-Potts, C B Newgar. Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia. Diabetes. vol 48. issue 10. 1999-10-19. PMID:10512368. |
animals with the lower degree of gk overexpression exhibited no significant changes in circulating glucose, ffas, insulin, tg, or lactate levels relative to controls that received a virus encoding a catalytically inactive mutant gk (adcmv-gk203), but did show a modest increase in lactate (58%) relative to adcmv-betagal-infused controls. |
1999-10-19 |
2023-08-12 |
rat |
| L Mantha, E Palacios, Y Deshaie. Modulation of triglyceride metabolism by glucocorticoids in diet-induced obesity. The American journal of physiology. vol 277. issue 2. 1999-09-23. PMID:10444552. |
the hsf diet also increased the acute postprandial rise in plasma insulin (4-fold) and tg (3-fold), fasting liver tg content (3-fold), triglyceridemia (54%), and adipose tissue lipoprotein lipase (lpl) activity (2-fold). |
1999-09-23 |
2023-08-12 |
rat |
| S Graci, R Baratta, C Degano, A Luppa, R Vigneri, L Frittitta, V Trischitt. The intravenous insulin tolerance test is an accurate method for screening a general population for insulin resistance and related abnormalities. Journal of endocrinological investigation. vol 22. issue 6. 1999-09-20. PMID:10435858. |
to verify whether the short intravenous insulin tolerance test (itt) (a safe, reproducible, inexpensive, rapid and easy to perform measurement of insulin sensitivity) is a suitable test for insulin resistance screening in a general population, we measured in 60 non diabetic subjects, either non-obese (no.=40) or obese (bmi>28, no.=20) the k of glucose disappearance from plasma after itt (k(itt)), plasma glucose (pg) and insulin (iri) both fasting (fpg, firi) and at 120 min of ogtt (pg- 120, iri- 120), and also triglycerides (tg), cholesterol (chol) and blood pressure (bp). |
1999-09-20 |
2023-08-12 |
human |
| S Graci, R Baratta, C Degano, A Luppa, R Vigneri, L Frittitta, V Trischitt. The intravenous insulin tolerance test is an accurate method for screening a general population for insulin resistance and related abnormalities. Journal of endocrinological investigation. vol 22. issue 6. 1999-09-20. PMID:10435858. |
average fpg, pg-120, firi, iri-120, tg and chol values were progressively increased, and average hdl/chol was progressively decreased from quartile 1 (the most insulin sensitive) to 4 (the most insulin resistant) (p<0.05, by 1-way anova test). |
1999-09-20 |
2023-08-12 |
human |
| V De Mitrio, G De Pergola, R Vettor, R Marino, M Sciaraffia, C Pagano, F A Scaraggi, L Di Lorenzo, R Giorgin. Plasma plasminogen activator inhibitor-I is associated with plasma leptin irrespective of body mass index, body fat mass, and plasma insulin and metabolic parameters in premenopausal women. Metabolism: clinical and experimental. vol 48. issue 8. 1999-09-07. PMID:10459558. |
sixty-one nondiabetic women aged 18 to 45 years with a wide range of values for the body mass index ([bmi] 18.1 to 37.7 kg/m2) were evaluated for (1) body fm and fasting plasma levels of (2) pai-1 antigen, (3) pai-1 activity, (4) leptin, (5) insulin, (6) blood glucose, and (7) lipids (cholesterol, high-density lipoprotein [hdl]-cholesterol, and triglycerides [tg]). |
1999-09-07 |
2023-08-12 |
human |