| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Reed, K Meszaros, L J Entes, M D Claypool, J G Pinkett, T M Gadbois, G M Reave. A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat. Metabolism: clinical and experimental. vol 49. issue 11. 2000-12-14. PMID:11092499. |
before stz injection, fat-fed rats had similar glucose concentrations to chow-fed rats, but significantly higher insulin, free fatty acid (ffa), and triglyceride (tg) concentrations (p < .01 to .0001). |
2000-12-14 |
2023-08-12 |
human |
| M J Reed, K Meszaros, L J Entes, M D Claypool, J G Pinkett, T M Gadbois, G M Reave. A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat. Metabolism: clinical and experimental. vol 49. issue 11. 2000-12-14. PMID:11092499. |
stz injection increased glucose (p < .05), insulin (p < .05), ffa (p < .05), and tg (p < .0001) concentrations in fat-fed rats (fat-fed/stz rats) compared with chow-fed, stz-injected rats (chow-fed/stz rats). |
2000-12-14 |
2023-08-12 |
human |
| T McLaughlin, F Abbasi, C Lamendola, H Yeni-Komshian, G Reave. Carbohydrate-induced hypertriglyceridemia: an insight into the link between plasma insulin and triglyceride concentrations. The Journal of clinical endocrinology and metabolism. vol 85. issue 9. 2000-10-16. PMID:10999790. |
this study was initiated to test the hypothesis that endogenous hypertriglyceridemia results from a defect in the ability of insulin to inhibit the release of very low-density lipoprotein-triglyceride (tg) from the liver. |
2000-10-16 |
2023-08-12 |
human |
| T McLaughlin, F Abbasi, C Lamendola, H Yeni-Komshian, G Reave. Carbohydrate-induced hypertriglyceridemia: an insight into the link between plasma insulin and triglyceride concentrations. The Journal of clinical endocrinology and metabolism. vol 85. issue 9. 2000-10-16. PMID:10999790. |
to accomplish this goal, plasma glucose, insulin, free fatty acid (ffa), and tg concentrations were compared in 12 healthy volunteers, in response to diets containing either 40% or 60% of total calories as carbohydrate (cho). |
2000-10-16 |
2023-08-12 |
human |
| T McLaughlin, F Abbasi, C Lamendola, H Yeni-Komshian, G Reave. Carbohydrate-induced hypertriglyceridemia: an insight into the link between plasma insulin and triglyceride concentrations. The Journal of clinical endocrinology and metabolism. vol 85. issue 9. 2000-10-16. PMID:10999790. |
the diets were consumed in random order, and measurements were made of plasma glucose, insulin, ffa, and tg concentrations at the end of each dietary period, fasting, and at hourly intervals following breakfast and lunch. |
2000-10-16 |
2023-08-12 |
human |
| T McLaughlin, F Abbasi, C Lamendola, H Yeni-Komshian, G Reave. Carbohydrate-induced hypertriglyceridemia: an insight into the link between plasma insulin and triglyceride concentrations. The Journal of clinical endocrinology and metabolism. vol 85. issue 9. 2000-10-16. PMID:10999790. |
the results indicated that the 60% cho diet resulted in higher fasting plasma tg concentrations associated with higher day-long plasma insulin and tg concentrations, and lower ffa concentrations. |
2000-10-16 |
2023-08-12 |
human |
| T McLaughlin, F Abbasi, C Lamendola, H Yeni-Komshian, G Reave. Carbohydrate-induced hypertriglyceridemia: an insight into the link between plasma insulin and triglyceride concentrations. The Journal of clinical endocrinology and metabolism. vol 85. issue 9. 2000-10-16. PMID:10999790. |
these results do not support the view that hypertriglyceridemia is secondary to a failure of insulin to inhibit hepatic tg secretion. |
2000-10-16 |
2023-08-12 |
human |
| K A Scribner, T M Gadbois, M Gowri, S Azhar, G M Reave. Masoprocol decreases serum triglyceride concentrations in rats with fructose-induced hypertriglyceridemia. Metabolism: clinical and experimental. vol 49. issue 9. 2000-10-12. PMID:11016888. |
the present studies were undertaken to determine if masoprocol also decreases tg concentrations in rats with fructose-induced hypertriglyceridemia (htg), a nondiabetic model of htg associated with insulin resistance and hyperinsulinemia. |
2000-10-12 |
2023-08-12 |
rat |
| D M Jia, A Tabaru, H Nakamura, K I Fukumitsu, T Akiyama, M Otsuk. Troglitazone prevents and reverses dyslipidemia, insulin secretory defects, and histologic abnormalities in a rat model of naturally occurring obese diabetes. Metabolism: clinical and experimental. vol 49. issue 9. 2000-10-12. PMID:11016899. |
troglitazone had no influence on visceral adipose depots, but it significantly reduced fasting glucose, insulin, cholesterol, triglyceride (tg), and free fatty acid (ffa) levels. |
2000-10-12 |
2023-08-12 |
human |
| M S Gowri, R K Azhar, F B Kraemer, G M Reaven, S Azha. Masoprocol decreases rat lipolytic activity by decreasing the phosphorylation of HSL. American journal of physiology. Endocrinology and metabolism. vol 279. issue 3. 2000-09-19. PMID:10950827. |
the results indicate that oral administration of masoprocol to rats with fructose-induced hypertriglyceridemia significantly decreased their serum free fatty acid (ffa; p < 0.05), triglyceride (tg; p < 0.001), and insulin (p < 0.05) concentrations. |
2000-09-19 |
2023-08-12 |
rat |
| I Lemieux, A Pascot, C Couillard, B Lamarche, A Tchernof, N Alméras, J Bergeron, D Gaudet, G Tremblay, D Prud'homme, A Nadeau, J P Despré. Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men? Circulation. vol 102. issue 2. 2000-08-01. PMID:10889128. |
the present study tested the hypothesis that simple variables, such as waist circumference and fasting plasma triglyceride (tg) concentrations, could be used as screening tools for the identification of men characterized by a metabolic triad of nontraditional risk factors (elevated insulin and apolipoprotein [apo] b and small, dense ldl particles). |
2000-08-01 |
2023-08-12 |
Not clear |
| P W Baker, G F Gibbon. Effect of dietary fish oil on the sensitivity of hepatic lipid metabolism to regulation by insulin. Journal of lipid research. vol 41. issue 5. 2000-07-24. PMID:10787432. |
insulin stimulation of fatty acid incorporation into triglyceride (tg) was also less pronounced in hepatocytes from the fo-fed group than in those from the oo-fed group but there was no difference in the stimulatory effect of insulin on fatty acid incorporation into phospholipid (pl) in these two groups. |
2000-07-24 |
2023-08-12 |
rat |
| P W Baker, G F Gibbon. Effect of dietary fish oil on the sensitivity of hepatic lipid metabolism to regulation by insulin. Journal of lipid research. vol 41. issue 5. 2000-07-24. PMID:10787432. |
in the case of fatty acid incorporation into both pl and tg, hepatocytes from the lf group were refractory to stimulation by insulin. |
2000-07-24 |
2023-08-12 |
rat |
| P W Baker, G F Gibbon. Effect of dietary fish oil on the sensitivity of hepatic lipid metabolism to regulation by insulin. Journal of lipid research. vol 41. issue 5. 2000-07-24. PMID:10787432. |
at each concentration of insulin, hepatocytes from the fo-fed group secreted less very low density lipoprotein (vldl) tg than those from the other groups. |
2000-07-24 |
2023-08-12 |
rat |
| P W Baker, G F Gibbon. Effect of dietary fish oil on the sensitivity of hepatic lipid metabolism to regulation by insulin. Journal of lipid research. vol 41. issue 5. 2000-07-24. PMID:10787432. |
however, the absolute suppression of vldl tg secretion by insulin was similar irrespective of the diet of the donor animals.we conclude that chronic consumption of a particular type of dietary fat does not affect the insulin sensitivity of the major pathways of hepatic lipid metabolism in a consistent manner. |
2000-07-24 |
2023-08-12 |
rat |
| J B Albu, A J Kovera, J A Johnso. Fat distribution and health in obesity. Annals of the New York Academy of Sciences. vol 904. 2000-07-10. PMID:10865794. |
in the past five years, we have used various methods to measure visceral versus subcutaneous fat distribution in caucasian (c) and african-american (aa) women and have related it to insulin sensitivity (si) and to blood lipids, particularly fasting serum triglyceride levels (tg). |
2000-07-10 |
2023-08-12 |
Not clear |
| C Snehalatha, S Sivasankari, K Satyavani, V Vijay, A Ramachandra. Postprandial hypertriglyceridaemia in treated type 2 diabetic subjects --the role of dietary components. Diabetes research and clinical practice. vol 48. issue 1. 2000-05-02. PMID:10704701. |
therefore the postprandial rise in tg was probably due to the high fat content of the diet and due to a lower insulin sensitivity. |
2000-05-02 |
2023-08-12 |
human |
| T Nagao, H Watanabe, N Goto, K Onizawa, H Taguchi, N Matsuo, T Yasukawa, R Tsushima, H Shimasaki, H Itakur. Dietary diacylglycerol suppresses accumulation of body fat compared to triacylglycerol in men in a double-blind controlled trial. The Journal of nutrition. vol 130. issue 4. 2000-04-24. PMID:10736331. |
serum lipid concentrations (tg, total cholesterol, free fatty acid) and related metabolites (glucose, insulin, total ketone body) did not change significantly in either group. |
2000-04-24 |
2023-08-12 |
human |
| S Ogawa, K Takeuchi, K Sugimura, M Fukuda, R Lee, S Ito, T Sat. Bezafibrate reduces blood glucose in type 2 diabetes mellitus. Metabolism: clinical and experimental. vol 49. issue 3. 2000-04-07. PMID:10726910. |
in protocol 2, fasting tg, pg, and insulin levels were significantly reduced by bezafibrate treatment. |
2000-04-07 |
2023-08-12 |
Not clear |
| S Ogawa, K Takeuchi, K Sugimura, M Fukuda, R Lee, S Ito, T Sat. Bezafibrate reduces blood glucose in type 2 diabetes mellitus. Metabolism: clinical and experimental. vol 49. issue 3. 2000-04-07. PMID:10726910. |
moreover, in the mtt, postprandial increments of tg were significantly blunted after bezafibrate treatment, whereas postprandial pg and insulin levels were not significantly changed. |
2000-04-07 |
2023-08-12 |
Not clear |