| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Candice A Allister, Li-fen Liu, Cindy A Lamendola, Colleen M Craig, Samuel W Cushman, Marc K Hellerstein, Tracey L McLaughli. In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans. Journal of lipid research. vol 56. issue 2. 2015-10-20. PMID:25418322. |
we directly tested this hypothesis by measuring, in vivo, tg synthesis, de novo lipogenesis (dnl), adipocyte proliferation, and insulin suppression of lipolysis in subcutaneous adipose tissue of bmi-matched individuals classified as insulin resistant (ir) or insulin sensitive (is). |
2015-10-20 |
2023-08-13 |
human |
| Candice A Allister, Li-fen Liu, Cindy A Lamendola, Colleen M Craig, Samuel W Cushman, Marc K Hellerstein, Tracey L McLaughli. In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans. Journal of lipid research. vol 56. issue 2. 2015-10-20. PMID:25418322. |
relative inability to store tg in the subcutaneous depot may represent a mechanism contributing to the development of insulin resistance in the setting of obesity. |
2015-10-20 |
2023-08-13 |
human |
| Chu-Fang Chou, Xiaolin Zhu, Yi-Yu Lin, Karen L Gamble, W Timothy Garvey, Ching-Yi Che. KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression. Journal of lipid research. vol 56. issue 2. 2015-10-20. PMID:25514904. |
excess accumulation of hepatic tg is a hallmark of nonalcoholic fatty liver disease, which is associated with obesity and insulin resistance. |
2015-10-20 |
2023-08-13 |
Not clear |
| Ming Huang, Fengqin Wang, Xihong Zhou, Hangxian Yang, Yizhen Wan. Hypoglycemic and hypolipidemic properties of polysaccharides from Enterobacter cloacae Z0206 in KKAy mice. Carbohydrate polymers. vol 117. 2015-10-12. PMID:25498613. |
improved oral glucose tolerance, reduced serum insulin levels as well as decreased serum triglycerides (tg), cholesterol (tc) and low density lipoprotein cholesterol (ldl-c) were observed after treatment with eps. |
2015-10-12 |
2023-08-13 |
mouse |
| Young Taek Oh, Dat Tran, Thomas A Buchanan, Michael E Selsted, Jang H You. θ-Defensin RTD-1 improves insulin action and normalizes plasma glucose and FFA levels in diet-induced obese rats. American journal of physiology. Endocrinology and metabolism. vol 309. issue 2. 2015-10-12. PMID:25991648. |
plasma glucose, ffa, triglyceride (tg), and insulin levels increased in dio rats; rtd-1 normalized plasma glucose and ffa levels and showed tendencies to lower plasma insulin and tg levels. |
2015-10-12 |
2023-08-13 |
rat |
| Yao Zhang, Chunjiu Ren, Guobing Lu, Weizheng Cui, Zhimei Mu, Huiju Gao, Yanwen Wan. Purification, characterization and anti-diabetic activity of a polysaccharide from mulberry leaf. Regulatory toxicology and pharmacology : RTP. vol 70. issue 3. 2015-10-08. PMID:25455227. |
oral administration of mlp at 50-200mg/kgbodyweight daily for 5weeks significantly reduced the levels of fasting blood glucose (fbg), glycosylated serum protein (gsp), serum total cholesterol (tc), and serum triglyceride (tg), and increased the body weight, fasting insulin (fins), c-peptide (c-p), liver glycogen, liver glucokinase, and serum high-density lipoprotein cholesterol (hdl-c). |
2015-10-08 |
2023-08-13 |
rat |
| Liying Zhang, Shanying Chen, Aiwen Deng, Xinyu Liu, Yan Liang, Xiaofei Shao, Mingxia Sun, Hequn Zo. Association between lipid ratios and insulin resistance in a Chinese population. PloS one. vol 10. issue 1. 2015-10-06. PMID:25635876. |
to explore the association of lipid ratios and triglyceride (tg) with insulin resistance (ir) in a chinese population. |
2015-10-06 |
2023-08-13 |
Not clear |
| Moe Thuzar, Vasant V Shenoy, Usman H Malabu, Ryan Schrale, Kunwarjit S Sangl. Extreme hypertriglyceridemia managed with insulin. Journal of clinical lipidology. vol 8. issue 6. 2015-09-30. PMID:25499946. |
we retrospectively reviewed 10 cases of extreme hypertriglyceridemia with mean serum tg on presentation of 101.5 ± 23.4 mmol/l (8982 ± 2070 mg/dl) managed with insulin. |
2015-09-30 |
2023-08-13 |
Not clear |
| Moe Thuzar, Vasant V Shenoy, Usman H Malabu, Ryan Schrale, Kunwarjit S Sangl. Extreme hypertriglyceridemia managed with insulin. Journal of clinical lipidology. vol 8. issue 6. 2015-09-30. PMID:25499946. |
serum tg decreased by 87 ± 4% in 24 hours in those patients managed with intravenous insulin and fasting and 40 ± 8.4% in those managed with intravenous insulin alone (p = .0003). |
2015-09-30 |
2023-08-13 |
Not clear |
| Samad Akbarzadeh, Fatemeh Eskandari, Hadis Tangestani, Somaieh Tangerami Bagherinejad, Afshar Bargahi, Parviz Bazzi, Adel Daneshi, Azam Sahrapoor, William J O'Connor, Ali Reza Rahba. The effect of Stevia rebaudiana on serum omentin and visfatin level in STZ-induced diabetic rats. Journal of dietary supplements. vol 12. issue 1. 2015-09-23. PMID:24689449. |
at the end of the study significant reductions in fasting blood sugar (fbs), the homeostasis model assessment insulin resistance (homa-ir), triglyceride (tg), alkaline phosphatase (alp), and omentin level were found in groups 3 and 4 in comparison with group 2. |
2015-09-23 |
2023-08-12 |
rat |
| Yun-Ying Huang, Xiong-Qin Huang, Li-Yan Zhao, Fang-Yun Sun, Wen-Liang Chen, Jie-Yi Du, Feng Yuan, Jie Li, Xue-Lian Huang, Jie Liu, Xiao-Fei Lv, Yong-Yuan Guan, Jian-Wen Chen, Guan-Lei Wan. ClC-3 deficiency protects preadipocytes against apoptosis induced by palmitate in vitro and in type 2 diabetes mice. Apoptosis : an international journal on programmed cell death. vol 19. issue 11. 2015-09-04. PMID:25218423. |
moreover, the enhanced apoptosis was shown in preadipocytes from high-sucrose/fat, low-dose stz induced t2dm mouse model with hyperglycemia, hyperlipidemia (elevated serum tg and ffa levels) and insulin resistance. |
2015-09-04 |
2023-08-13 |
mouse |
| Jimena Soutelo, Mariana Grüneisen, Clara Fritz, Laura Sordo, Yanina Powazniak, Rubén Lutf. [Familial partial lipodystrophy type 1. A rare or underdiagnosed syndrome?]. Medicina. vol 75. issue 1. 2015-08-31. PMID:25637899. |
changes in lifestyle and treatment with fenofibrate, biphasic insulin 50/50, and enalapril were initiated showing a a significant metabolic improvement: hba1c (7.8%) and tg (243 mg/dl). |
2015-08-31 |
2023-08-13 |
Not clear |
| Mei-Qin Zhuo, Zhi Luo, Kun Wu, Qing-Ling Zhu, Jia-Lang Zheng, Li-Han Zhang, Qi-Liang Che. Regulation of insulin on lipid metabolism in freshly isolated hepatocytes from yellow catfish (Pelteobagrus fulvidraco). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 177-178. 2015-08-24. PMID:25139481. |
insulin incubation enhanced lipogenesis and reduced lipolysis of freshly isolated hepatocytes of yellow catfish, in coincidence with increased tg content. |
2015-08-24 |
2023-08-13 |
Not clear |
| Natalia A Tamarina, Michael W Roe, Lh Philipso. Characterization of mice expressing Ins1 gene promoter driven CreERT recombinase for conditional gene deletion in pancreatic β-cells. Islets. vol 6. issue 1. 2015-08-24. PMID:25483876. |
cdna encoding cre recombinase fused to modified estrogen receptor (creert) under control of mouse insulin 1 gene promoter (ins1) was used to construct the mouse line tg(ins1-cre/ert)1lphi, also termed mip1-creert. |
2015-08-24 |
2023-08-13 |
mouse |
| Linhong He, Heying Pei, Liang Ma, Yuzhi Pu, Jinying Chen, Zhuowei Liu, Yan Ran, Lei Lei, Suhong Fu, Minghai Tang, Aihua Peng, Chaofeng Long, Lijuan Che. Synthesis and lipid-lowering evaluation of 3-methyl-1H-purine-2,6-dione derivatives as potent and orally available anti-obesity agents. European journal of medicinal chemistry. vol 87. 2015-08-19. PMID:25299682. |
obesity accompanied with metabolic disorder is often complicated with a strong link of dyslipidemia and insulin resistance, whose indicator is the excess accumulation of triglycerides (tg) in cells. |
2015-08-19 |
2023-08-13 |
mouse |
| Linhong He, Heying Pei, Liang Ma, Yuzhi Pu, Jinying Chen, Zhuowei Liu, Yan Ran, Lei Lei, Suhong Fu, Minghai Tang, Aihua Peng, Chaofeng Long, Lijuan Che. Synthesis and lipid-lowering evaluation of 3-methyl-1H-purine-2,6-dione derivatives as potent and orally available anti-obesity agents. European journal of medicinal chemistry. vol 87. 2015-08-19. PMID:25299682. |
thus, 11c·hcl might be a potent and orally available anti-obesity agent via alleviating the obese clinical symptoms, body fat, improving serum parameters and insulin resistance and tg clearance in liver. |
2015-08-19 |
2023-08-13 |
mouse |
| A Sessa, A Esposito, A Giliberti, G Iavicoli, C Costa, M Bergallo, E Lettieri, R Rossano, M Capuan. Immunosuppressive agents and metabolic factors of cardiovascular risk in renal transplant recipients. Transplantation proceedings. vol 41. issue 4. 2015-08-18. PMID:19460510. |
we measured uric acid, triglycerides (tg), low-density lipoprotein (ldl)/high-density lipoprotein (hdl) ldl/hdl ratio, homocysteine (homo), insulin resistance, mualb, c-reactive protein (crp), and fibrinogen. |
2015-08-18 |
2023-08-12 |
Not clear |
| Jaideep Behari, Huanan Li, Shiguang Liu, Maja Stefanovic-Racic, Laura Alonso, Christopher P O'Donnell, Sruti Shiva, Srikanth Singamsetty, Yoshio Watanabe, Vijay P Singh, Qing Li. β-catenin links hepatic metabolic zonation with lipid metabolism and diet-induced obesity in mice. The American journal of pathology. vol 184. issue 12. 2015-08-12. PMID:25300578. |
hfd-fed tg mice rapidly developed diet-induced obesity and systemic insulin resistance, but ko mice were resistant to diet-induced obesity. |
2015-08-12 |
2023-08-13 |
mouse |
| Sadashiv, Sunita Tiwari, Vani Gupta, Bhola Nath Paul, Sandeep Kumar, Abhijit Chandra, S Dhananjai, Mahendra Pal Singh Negi, Ashim Ghata. IL-6 gene expression in adipose tissue of postmenopausal women and its association with metabolic risk factors. Molecular and cellular endocrinology. vol 399. 2015-08-05. PMID:25301326. |
the results showed significantly (p < 0.05 or p < 0.01 or p < 0.001) higher mean sbp, glucose, insulin, homa, tg, vldl and serum il-6 while significantly (p < 0.001) lower hdl and estrogen in cases as compared to controls. |
2015-08-05 |
2023-08-13 |
Not clear |
| Wei Xu, Qing Zhou, Jiao-jiao Yin, Yong Yao, Jiu-liang Zhan. Anti-diabetic effects of polysaccharides from Talinum triangulare in streptozotocin (STZ)-induced type 2 diabetic male mice. International journal of biological macromolecules. vol 72. 2015-08-04. PMID:25236607. |
the ttp hypoglycemic and hypolipidemic effects were evaluated by testing the fast blood glucose (fbg) level, fasting serum insulin (fins), and serum lipids (tc, tg, hdl, ldl) as well as the body, hepar and kidney weights. |
2015-08-04 |
2023-08-13 |
mouse |