| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haiyan Zhang, Yihang Li, Jie Hu, Wen-Jun Shen, Madhurima Singh, Xiaoming Hou, Alex Bittner, Stefanie Bittner, Yuan Cortez, Juveria Tabassum, Fredric B Kraemer, Salman Azha. Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis. PloS one. vol 10. issue 9. 2016-05-31. PMID:26394137. |
nordihydroguaiaretic acid (ndga), the main metabolite of creosote bush, has been shown to have profound effects on the core components of the metabolic syndrome (mets), lowering blood glucose, free fatty acids (ffa) and triglyceride (tg) levels in several models of dyslipidemia, as well as improving body weight (obesity), insulin resistance, diabetes and hypertension, and ameliorating hepatic steatosis. |
2016-05-31 |
2023-08-13 |
rat |
| Haiyan Zhang, Yihang Li, Jie Hu, Wen-Jun Shen, Madhurima Singh, Xiaoming Hou, Alex Bittner, Stefanie Bittner, Yuan Cortez, Juveria Tabassum, Fredric B Kraemer, Salman Azha. Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis. PloS one. vol 10. issue 9. 2016-05-31. PMID:26394137. |
in the hfrd treatment group, ndga administration by oral gavage decreased plasma levels of tg, glucose, ffa, and insulin, increased hepatic mitochondrial fatty acid oxidation and attenuated hepatic tg accumulation. |
2016-05-31 |
2023-08-13 |
rat |
| Jintian He, Li Dong, Wen Xu, Kaiwen Bai, Changhui Lu, Yanan Wu, Qiang Huang, Lili Zhang, Tian Wan. Dietary Tributyrin Supplementation Attenuates Insulin Resistance and Abnormal Lipid Metabolism in Suckling Piglets with Intrauterine Growth Retardation. PloS one. vol 10. issue 8. 2016-05-24. PMID:26317832. |
piglets with iugr showed higher (p < 0.05) concentrations of insulin in the serum, higher (p < 0.05) homa-ir and total cholesterol, triglycerides (tg), non-esterified fatty acid (nefa) in the liver, and lower (p < 0.05) enzyme activities (hepatic lipase [hl], lipoprotein lipase [lpl], total lipase [tl]) and concentration of glycogen in the liver than the nbw group. |
2016-05-24 |
2023-08-13 |
Not clear |
| Jintian He, Li Dong, Wen Xu, Kaiwen Bai, Changhui Lu, Yanan Wu, Qiang Huang, Lili Zhang, Tian Wan. Dietary Tributyrin Supplementation Attenuates Insulin Resistance and Abnormal Lipid Metabolism in Suckling Piglets with Intrauterine Growth Retardation. PloS one. vol 10. issue 8. 2016-05-24. PMID:26317832. |
tb supplementation decreased (p < 0.05) the concentrations of insulin, homa-ir, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in the serum, and the concentrations of tg and nefa in the liver, and increased (p < 0.05) enzyme activities (hl, lpl, and tl) and concentration of glycogen in the liver of the it group. |
2016-05-24 |
2023-08-13 |
Not clear |
| Fahim Abbasi, QueenDenise Okeke, Gerald M Reave. Evaluation of fasting plasma insulin concentration as an estimate of insulin action in nondiabetic individuals: comparison with the homeostasis model assessment of insulin resistance (HOMA-IR). Acta diabetologica. vol 51. issue 2. 2016-05-19. PMID:23420066. |
measurements were made of fpg, fpi, triglyceride (tg), and high-density lipoprotein cholesterol (hdl-c) concentrations, and insulin-mediated glucose uptake was quantified by determining steady-state plasma glucose (sspg) concentration during the insulin suppression test. |
2016-05-19 |
2023-08-12 |
Not clear |
| Yuncui Yu, Jing Wang, Ruiying Kang, Jing Dong, Yuxiang Zhang, Fen Liu, Yuxiang Yan, Rong Zhu, Lili Xia, Xiaoxia Peng, Ling Zhang, Dian He, Herbert Y Gaisano, Gaisano Herbert, Zhenwen Chen, Yan H. Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population. Lipids in health and disease. vol 14. 2016-05-18. PMID:26377690. |
in our previous study, we had assessed in the chinese han population the association of kcnb1 rs1051295 with metabolic traits indicating metabolic syndrome, and showed that kcnb1 rs1051295 genotype tt was associated with increase of waist to hip ratio (whr), fasting insulin (fins), triglycerides (tg) and decreased insulin sensitivity at basal condition. |
2016-05-18 |
2023-08-13 |
Not clear |
| Hailong Hu, Qian Guo, Changlin Wang, Xiao Ma, Hongjuan He, Yuri Oh, Yujie Feng, Qiong Wu, Ning G. Titanium dioxide nanoparticles increase plasma glucose via reactive oxygen species-induced insulin resistance in mice. Journal of applied toxicology : JAT. vol 35. issue 10. 2016-05-17. PMID:25826740. |
biochemical analyzes included plasma glucose, insulin, heart blood triglycerides (tg), free fatty acid (ffa), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), total cholesterol (tc), tumor necrosis factor-alpha (tnf-α), interleukin (il)-6 and reactive oxygen species (ros)-related markers (total sod, gsh and mda). |
2016-05-17 |
2023-08-13 |
mouse |
| D D Li, D Y Su, L Xue, W Gao, W Y Pan. Relationship between a lipoprotein lipase gene polymorphism in placental tissue and insulin resistance in patients with gestational diabetes mellitus. Genetics and molecular research : GMR. vol 14. issue 3. 2016-05-16. PMID:26214456. |
the relationships between fasting plasma glucose (fpg), postprandial plasma glucose (ppg), fasting insulin (fins), cholesterol (tc), triglyceride (tg), high density lipoprotein (hdl), low density lipoprotein (ldl), body mass index (bmi), and ir indices and the lpl polymorphism in the two study groups and their offspring were determined. |
2016-05-16 |
2023-08-13 |
Not clear |
| Iwona Rotter, Danuta Kosik-Bogacka, Barbara Dołęgowska, Krzysztof Safranow, Anna Lubkowska, Maria Laszczyńsk. Relationship between the concentrations of heavy metals and bioelements in aging men with metabolic syndrome. International journal of environmental research and public health. vol 12. issue 4. 2016-05-12. PMID:25867198. |
heavy metals-lead (pb), cadmium (cd), mercury (hg), arsenic (as), tungsten (w), macroelements-magnesium (mg) and calcium (ca), and microelements-iron (fe), zinc (zn) copper (cu), chromium (cr), molybdenum (mo), selenium (se) and manganese (mn), body mass index (bmi), waist to hip ratio (whr), abdominal circumference (ac) and blood pressure (bp), total cholesterol (tch), high-density lipoprotein (hdl), low-density lipoprotein (ldl), triglyceride (tg), fasting plasma glucose (fpg), insulin, and homeostasis model assessment-insulin resistance (homa-ir). |
2016-05-12 |
2023-08-13 |
human |
| Jianfeng Liang, Junfen Fu, Youyun Jiang, Guanping Dong, Xiumin Wang, Wei W. TriGlycerides and high-density lipoprotein cholesterol ratio compared with homeostasis model assessment insulin resistance indexes in screening for metabolic syndrome in the chinese obese children: a cross section study. BMC pediatrics. vol 15. 2016-05-09. PMID:26416207. |
this study aims to investigate the optimal cut-off values, compare the accuracy for the (triglycerides (tg) to high-density lipoprotein cholesterol (hdl-c)) (tg/hdl-c) ratio and homeostasis model assessment insulin resistance (homa-ir) indexs to identify metabolic syndrome in obese pediatric population in china. |
2016-05-09 |
2023-08-13 |
Not clear |
| Marilyne Labrie, Simon Lalonde, Ouafa Najyb, Maxime Thiery, Caroline Daneault, Chrisitne Des Rosiers, Eric Rassart, Catherine Mounie. Apolipoprotein D Transgenic Mice Develop Hepatic Steatosis through Activation of PPARγ and Fatty Acid Uptake. PloS one. vol 10. issue 6. 2016-04-28. PMID:26083030. |
despite the use of a neuron-specific promoter to generate the tg mice, they expressed significant levels of h-apod in both plasma and liver and they slowly develop hepatic steatosis and insulin resistance. |
2016-04-28 |
2023-08-13 |
mouse |
| X Lin, Z Zhang, J M Chen, Y Y Xu, H R Ye, J Cui, Y Fang, Y Jin, D R Zhu, L Yua. Role of APN and TNF-α in type 2 diabetes mellitus complicated by nonalcoholic fatty liver disease. Genetics and molecular research : GMR. vol 14. issue 2. 2016-04-21. PMID:25966055. |
body mass index, fasting blood plasma glucose (fpg), fasting insulin, triglyceride (tg), alanine aminotransferase, gamma-glutamyl transpeptidase, apn, tnf-α, and homeostasis model of assessment (homa)-ir were determined. |
2016-04-21 |
2023-08-13 |
Not clear |
| X Lin, Z Zhang, J M Chen, Y Y Xu, H R Ye, J Cui, Y Fang, Y Jin, D R Zhu, L Yua. Role of APN and TNF-α in type 2 diabetes mellitus complicated by nonalcoholic fatty liver disease. Genetics and molecular research : GMR. vol 14. issue 2. 2016-04-21. PMID:25966055. |
tnf-α was negatively correlated with apn, but positively correlated with fpg, fasting insulin, tg, and homa-ir. |
2016-04-21 |
2023-08-13 |
Not clear |
| Bhesh Raj Sharma, Jin Oh, Hyeon-A Kim, Yong Jae Kim, Kyu-Shik Jeong, Dong Young Rhy. Anti-Obesity Effects of the Mixture of Eriobotrya japonica and Nelumbo nucifera in Adipocytes and High-Fat Diet-Induced Obese Mice. The American journal of Chinese medicine. vol 43. issue 4. 2016-04-19. PMID:26133751. |
in our results, the administration of ej, nn, and mix significantly decreased body weight (bw), fat weight, liver weight, hepatic triglyceride (tg) and total cholesterol (tc), lipid droplets in the liver, food efficacy ratio, and the plasma tg, tc, glucose, insulin, alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels in a dose-dependent manner, and mix treatment showed stronger effect than their individual treatments. |
2016-04-19 |
2023-08-13 |
mouse |
| Daniel S Lark, Li Kang, Mary E Lustig, Jeffrey S Bonner, Freyja D James, P Darrell Neufer, David H Wasserma. Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse. PloS one. vol 10. issue 5. 2016-04-15. PMID:25992608. |
furthermore, muscle insulin action is partially preserved in high fat (hf)-fed mcat(tg) mice. |
2016-04-15 |
2023-08-13 |
mouse |
| Daniel S Lark, Li Kang, Mary E Lustig, Jeffrey S Bonner, Freyja D James, P Darrell Neufer, David H Wasserma. Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse. PloS one. vol 10. issue 5. 2016-04-15. PMID:25992608. |
insulin action was examined in conscious, unrestrained and unstressed wild type (wt), sod2(tg), mcat(tg) and mtao mice using hyperinsulinemic-euglycemic clamps (insulin clamps) combined with radioactive glucose tracers following sixteen weeks of normal chow or hf (60% calories from fat) feeding. |
2016-04-15 |
2023-08-13 |
mouse |
| Daniel S Lark, Li Kang, Mary E Lustig, Jeffrey S Bonner, Freyja D James, P Darrell Neufer, David H Wasserma. Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse. PloS one. vol 10. issue 5. 2016-04-15. PMID:25992608. |
glucose infusion rates, whole body glucose disappearance, and muscle glucose uptake during the insulin clamp were similar in chow- and hf-fed wt and sod2(tg) mice. |
2016-04-15 |
2023-08-13 |
mouse |
| Daniel S Lark, Li Kang, Mary E Lustig, Jeffrey S Bonner, Freyja D James, P Darrell Neufer, David H Wasserma. Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse. PloS one. vol 10. issue 5. 2016-04-15. PMID:25992608. |
consistent with our previous work, hf-fed mcat(tg) mice had improved muscle insulin action, however, an additive effect was not seen in mtao mice. |
2016-04-15 |
2023-08-13 |
mouse |
| Alper Sonmez, Mahmut Ilker Yilmaz, Mutlu Saglam, Hilmi Umut Unal, Mahmut Gok, Hakki Cetinkaya, Murat Karaman, Cem Haymana, Tayfun Eyileten, Yusuf Oguz, Abdulgaffar Vural, Manfredi Rizzo, Peter P Tot. The role of plasma triglyceride/high-density lipoprotein cholesterol ratio to predict cardiovascular outcomes in chronic kidney disease. Lipids in health and disease. vol 14. 2016-04-08. PMID:25885289. |
the triglycerides (tg) to high-density lipoprotein cholesterol (hdl-c) ratio is an indirect measure of insulin resistance and an independent predictor of cardiovascular risk. |
2016-04-08 |
2023-08-13 |
human |
| Samuel S Gidding, Scott W Keith, Bonita Falkne. Adolescent and adult African Americans have similar metabolic dyslipidemia. Journal of clinical lipidology. vol 9. issue 3. 2016-03-10. PMID:26073396. |
african americans (aas) have lower triglyceride (tg) and higher high-density lipoprotein cholesterol (hdl-c) than other ethnic groups; yet, they also have higher risk for developing diabetes mellitus despite the strong relationship of dyslipidemia with insulin resistance. |
2016-03-10 |
2023-08-13 |
Not clear |