| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qinwen Bao, Xiaozhu Shen, Li Qian, Chen Gong, Maoxiao Nie, Yan Don. Anti-diabetic activities of catalpol in db/db mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 20. issue 2. 2016-03-03. PMID:26937211. |
after 4 weeks of treatment, the concentrations of fasting blood glucose (fbg), glycated serum protein (gsp), insulin (ins), triglyceride (tg), total cholesterol (tc) and adiponection (apn) in serum were detected. |
2016-03-03 |
2023-08-13 |
mouse |
| Qinwen Bao, Xiaozhu Shen, Li Qian, Chen Gong, Maoxiao Nie, Yan Don. Anti-diabetic activities of catalpol in db/db mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 20. issue 2. 2016-03-03. PMID:26937211. |
our results showed that catalpol could significantly improve the insulin resistance, decrease the serum concentrations of ins, gsp, tg, and tc. |
2016-03-03 |
2023-08-13 |
mouse |
| Jianhui Su, Hongxin Wang, Caoyang Ma, Zaixiang Lou, Chengxiang Liu, MdRamim Tanver Rahman, Chuanzhong Gao, Rongjing Ni. Anti-diabetic activity of peony seed oil, a new resource food in STZ-induced diabetic mice. Food & function. vol 6. issue 9. 2016-02-29. PMID:26245697. |
there were significant increases in body weight, liver glycogen content, serum insulin level, high-density lipoprotein cholesterol (hdl-c) and decreases in glycosylated hemoglobin (hba1c), total serum cholesterol (tc), and triglyceride (tg) in test groups as compared to the untreated diabetic groups. |
2016-02-29 |
2023-08-13 |
mouse |
| Surapon Tangvarasittichai, Suthap Pongthaisong, Orathai Tangvarasitticha. Tumor Necrosis Factor-Α, Interleukin-6, C-Reactive Protein Levels and Insulin Resistance Associated with Type 2 Diabetes in Abdominal Obesity Women. Indian journal of clinical biochemistry : IJCB. vol 31. issue 1. 2016-02-09. PMID:26855490. |
body mass index, waist circumference (wc), blood pressure (bp), plasma glucose (glu), triglyceride (tg), insulin, homa-ir and inflammatory cytokines were significantly higher and lower total antioxidant capacity, hdl-c in ao subjects (p < 0.05). |
2016-02-09 |
2023-08-13 |
human |
| Surapon Tangvarasittichai, Suthap Pongthaisong, Orathai Tangvarasitticha. Tumor Necrosis Factor-Α, Interleukin-6, C-Reactive Protein Levels and Insulin Resistance Associated with Type 2 Diabetes in Abdominal Obesity Women. Indian journal of clinical biochemistry : IJCB. vol 31. issue 1. 2016-02-09. PMID:26855490. |
wc was significantly correlated with bp, glu, tg, ldl-c, insulin, homa-ir, tnf-α, il-6 and negative correlation with hdl-c in ao subjects. |
2016-02-09 |
2023-08-13 |
human |
| Surapon Tangvarasittichai, Suthap Pongthaisong, Orathai Tangvarasitticha. Tumor Necrosis Factor-Α, Interleukin-6, C-Reactive Protein Levels and Insulin Resistance Associated with Type 2 Diabetes in Abdominal Obesity Women. Indian journal of clinical biochemistry : IJCB. vol 31. issue 1. 2016-02-09. PMID:26855490. |
elevation of tnf-α, il-6, hs-crp and insulin resistance were significantly associated with t2dm in ao subjects, after adjusting with insulin resistance, increased oxidative stress, elevated tg and reduced hdl-c by using multiple logistic regression analysis. |
2016-02-09 |
2023-08-13 |
human |
| Li-Wei Huang, Xiao-Meng Yang, Xiao-Lin Zhang, Li Wang, Li Wan. [The hepatic ChREBP expression and hyperinsulinemia in mice]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 6. 2016-02-02. PMID:25212036. |
as the results, in kkay mice, a positive correlation between the levels of serum insulin and glucose (r = 0.902, p < 0.000), as well as between the levels of serum insulin and tg (r = 0.732, p < 0.000), was observed. |
2016-02-02 |
2023-08-13 |
mouse |
| Li-Wei Huang, Xiao-Meng Yang, Xiao-Lin Zhang, Li Wang, Li Wan. [The hepatic ChREBP expression and hyperinsulinemia in mice]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 6. 2016-02-02. PMID:25212036. |
in dio mice, correlation between the levels of serum insulin and tg (r = 0.722, p < 0.001) also showed positive, and the expressions of hepatic chrebp, acc and fas increased significantly and also accompanied with its hyperinsulinemia. |
2016-02-02 |
2023-08-13 |
mouse |
| Ahmed Al-Dwairi, Adam R Brown, John Mark P Pabona, Trang H Van, Hamdan Hamdan, Charles P Mercado, Charles M Quick, Patricia A Wight, Rosalia C M Simmen, Frank A Simme. Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice. PloS one. vol 9. issue 11. 2016-01-19. PMID:25402228. |
the livers from hf diet-fed tg mice also exhibited an induction of cholesterol and lipogenic pathway genes and altered measures (irs1, irs2, prkce) of insulin sensitivity. |
2016-01-19 |
2023-08-13 |
mouse |
| Marzena Malara, Anna Kęska, Joanna Tkaczyk, Grażyna Lutosławsk. Body shape index versus body mass index as correlates of health risk in young healthy sedentary men. Journal of translational medicine. vol 13. 2016-01-19. PMID:25890016. |
bmi was slightly, but significantly correlated only with circulating tg (r=0.330, p < 0.001) in contrast, absi was slightly, but significantly correlated with plasma levels of insulin (r=0.360, p<0.001), tc (r=0.270, p<0.002), ldl-c and non-hdl-c (r=0.300, p<0.001). |
2016-01-19 |
2023-08-13 |
human |
| Darren C Henstridge, E Estevez, T L Allen, S E Heywood, T Gardner, C Yang, N A Mellett, B A Kingwell, P J Meikle, M A Febbrai. Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance. Cell stress & chaperones. vol 20. issue 3. 2016-01-14. PMID:25618331. |
although hfd-induced cardiac insulin resistance was not rescued in the hsp72 tg mice, it was preserved in the skeletal muscle, suggesting tissue-specific effects of hsp72 overexpression on substrate metabolism. |
2016-01-14 |
2023-08-13 |
mouse |
| Elena Flowers, César Molina, Ashish Mathur, Gerald M Reave. Use of plasma triglyceride/high-density lipoprotein cholesterol ratio to identify increased cardio-metabolic risk in young, healthy South Asians. The Indian journal of medical research. vol 141. issue 1. 2016-01-08. PMID:25857497. |
prevalence of insulin resistance and associated dyslipidaemia [high triglyceride (tg) and low high-density lipoprotein cholesterol (hdl-c) concentrations] are increased in south asian individuals; likely contributing to their increased risk of type-2 diabetes and cardiovascular disease. |
2016-01-08 |
2023-08-13 |
Not clear |
| Ahmed M Kabel, Maaly A Abd Elmaaboud, Ahmed A Albarra. Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. Prostaglandins, leukotrienes, and essential fatty acids. vol 96. 2015-12-28. PMID:25541279. |
serum alanine aminotransferase, total cholesterol (tc), triglycerides (tg), high density lipoproteins, insulin, glucose, c-reactive protein and quantitative insulin sensitivity check index were measured. |
2015-12-28 |
2023-08-13 |
rat |
| Hiroshi Nomoto, Takuma Kondo, Hideaki Miyoshi, Akinobu Nakamura, Yoko Hida, Ken-ichiro Yamashita, Arun J Sharma, Tatsuya Atsum. Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion. Endocrinology. vol 156. issue 10. 2015-12-15. PMID:25763640. |
dn-mafk tg mice under high-fat diet conditions showed improved glucose metabolism compared with control mice via incremental insulin secretion, without causing changes in insulin sensitivity or mafa expression. |
2015-12-15 |
2023-08-13 |
mouse |
| Li Ang, Liu Yuguang, Wang Liying, Zhang Shuying, Xu Liting, Wang Shumi. Ergosterol Alleviates Kidney Injury in Streptozotocin-Induced Diabetic Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-12-15. PMID:26664454. |
biochemical parameters such as uric acid, creatinine, serum insulin, triglycerides (tg), and total cholesterol (tc) were also measured. |
2015-12-15 |
2023-08-13 |
mouse |
| Yueh-Hsiung Kuo, Cheng-Hsiu Lin, Chun-Ching Shi. Ergostatrien-3β-ol from Antrodia camphorata inhibits diabetes and hyperlipidemia in high-fat-diet treated mice via regulation of hepatic related genes, glucose transporter 4, and AMP-activated protein kinase phosphorylation. Journal of agricultural and food chemistry. vol 63. issue 9. 2015-12-03. PMID:25693659. |
hfd-fed mice display increased blood glucose, glycated hemoglobin (hba1c), total cholesterol (tc), triglyceride (tg), insulin, and leptin levels. |
2015-12-03 |
2023-08-13 |
mouse |
| Jun Zhou, Junyan Yan, Zhaoshuai Bai, Kaicheng Li, Kaixun Huan. Hypoglycemic activity and potential mechanism of a polysaccharide from the loach in streptozotocin-induced diabetic mice. Carbohydrate polymers. vol 121. 2015-11-16. PMID:25659690. |
map oral administration significantly decreased the blood levels of glucose, tc, tg, ldl-c, and increased the blood levels of hdl-c and insulin in diabetic mice, concurrent with increases in body weights and pancreatic insulin contents. |
2015-11-16 |
2023-08-13 |
mouse |
| Rasool Soltani, Abdollah Gorji, Sedigheh Asgary, Nizal Sarrafzadegan, Mansour Siavas. Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-10-28. PMID:26508984. |
after 6 weeks of intervention, significant increase in insulin level (1.13 ± 1.90 versus -0.643 ± 1.82, p < 0.05) as well as decrease in hgba1c (-0.24 ± 0.429 versus 0.023 ± 0.225, p < 0.05) and tg (-23.66 ± 55.40 versus 2.83 ± 15.71, p < 0.05) levels was observed in drug group compared to placebo. |
2015-10-28 |
2023-08-13 |
Not clear |
| Rasool Soltani, Abdollah Gorji, Sedigheh Asgary, Nizal Sarrafzadegan, Mansour Siavas. Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-10-28. PMID:26508984. |
daily consumption of the fruit extract of cornus mas l. improves glycemic control by increasing insulin level and reduces tg serum level in type 2 diabetic adult patients. |
2015-10-28 |
2023-08-13 |
Not clear |
| Bi-Zhen Gao, Ji-Cheng Chen, Ling-Hong Liao, Jia-Qi Xu, Xiao-Feng Lin, Shan-Shan Din. Erchen Decoction Prevents High-Fat Diet Induced Metabolic Disorders in C57BL/6 Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-10-27. PMID:26504476. |
consistently, we observed that ecd significantly improved glucose tolerance, promoted the secretion of insulin and decreased the level of tg, tc level. |
2015-10-27 |
2023-08-13 |
mouse |