| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wen-Hua He, Min Yu, Yin Zhu, Liang Xia, Pi Liu, Hao Zeng, Yong Zhu, Nong-Hua L. Emergent Triglyceride-lowering Therapy With Early High-volume Hemofiltration Against Low-Molecular-Weight Heparin Combined With Insulin in Hypertriglyceridemic Pancreatitis: A Prospective Randomized Controlled Trial. Journal of clinical gastroenterology. vol 50. issue 9. 2017-12-05. PMID:27574886. |
to compare the value of emergent triglyceride (tg)-lowering therapies between early high-volume hemofiltration (hvhf) and low-molecular-weight heparin (lmwh) combined with insulin (lmwh+insulin) as well as their effects on the outcomes of hypertriglyceridemic pancreatitis (htgp) patients. |
2017-12-05 |
2023-08-13 |
Not clear |
| Tingting Xu, Zihua Weng, Chu Pei, Siyuan Yu, Yating Chen, Wenjie Guo, Xingzuo Wang, Peng Luo, Jia Su. The relationship between neutrophil-to-lymphocyte ratio and diabetic peripheral neuropathy in Type 2 diabetes mellitus. Medicine. vol 96. issue 45. 2017-12-04. PMID:29137012. |
student t test, mann-whitney u test, or χ test was applied to the data of the 2 groups, including the levels of neutrophils and lymphocytes as well as the nlr values of peripheral blood and other biochemistry indexes; pearson correlation analysis was used to calculate the correlation of nlr and detected factors; risk factors of dpn were estimated via logistic regression analysis and multivariate analysis.the values of triglyceride (tg), neutrophils, fasting insulin, urinary albumin, and 2 hour postglucose in dpn group were significantly higher than those of the dm group, whereas the number of lymphocytes of dpn group was considerably lower than that of the dm group (p < .05 respectively); nlr values were remarkably higher in dpn group compared with those of dm group (2.58 ± 0.50 vs 2.18 ± 0.61, p < .001); logistic regression analysis showed that nlr (p = .002, or = 4.960, 95% ci = 1.843-13.349) was a risk factor of dpn. |
2017-12-04 |
2023-08-13 |
Not clear |
| Thomas Grenier-Larouche, Anne-Marie Carreau, Alain Geloën, Frédérique Frisch, Laurent Biertho, Simon Marceau, Stéfane Lebel, Frédéric-Simon Hould, Denis Richard, André Tchernof, André C Carpentie. Fatty Acid Metabolic Remodeling During Type 2 Diabetes Remission After Bariatric Surgery. Diabetes. vol 66. issue 11. 2017-11-20. PMID:28835473. |
tg disposal and acylcarnitine production during lipid overload, along with muscle insulin sensitivity, improved with weight loss. |
2017-11-20 |
2023-08-13 |
human |
| Yukiko Fukuda, Yoshitaka Hashimoto, Masahide Hamaguchi, Takuya Fukuda, Naoto Nakamura, Akihiro Ohbora, Takahiro Kato, Takao Kojima, Michiaki Fuku. Triglycerides to high-density lipoprotein cholesterol ratio is an independent predictor of incident fatty liver; a population-based cohort study. Liver international : official journal of the International Association for the Study of the Liver. vol 36. issue 5. 2017-11-16. PMID:26444696. |
triglycerides (tg) to high-density lipoprotein cholesterol (hdl-c) ratio (tg/hdl-c) has been recommended for surrogates of insulin resistance. |
2017-11-16 |
2023-08-13 |
Not clear |
| Yun Huang, Chen Fang, Zhimin Ma, Heming Guo, Ruihua Wang, Ji H. Betatrophin Levels were Increased in Pregnant Women with or without Gestational Diabetes Mellitus and Associated with Beta Cell Function. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia. vol 38. issue 6. 2017-11-06. PMID:27399923. |
results our study found that pregnant women, regardless of their glucose regulation status, had remarkably higher triglycerides (tg), total cholesterol (tc), fasting insulin (fins), homeostasis model assessment of insulin resistance (homa-ir) and homeostasis model assessment of β-cell function (homa-β). |
2017-11-06 |
2023-08-13 |
human |
| Andres Digenio, Richard L Dunbar, Veronica J Alexander, Marcus Hompesch, Linda Morrow, Richard G Lee, Mark J Graham, Steven G Hughes, Rosie Yu, Walter Singleton, Brenda F Baker, Sanjay Bhanot, Rosanne M Crook. Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes. Diabetes care. vol 39. issue 8. 2017-11-03. PMID:27271183. |
to determine the effects of volanesorsen (isis 304801), a second-generation 2'-o-methoxyethyl chimeric antisense inhibitor of apolipoprotein (apo)c-iii, on triglyceride (tg) levels and insulin resistance in patients with type 2 diabetes. |
2017-11-03 |
2023-08-13 |
Not clear |
| Shenghua Li, Juan Tan, Junying Zeng, Xianjin Wu Xianjin Wu, Jian Zhan. Antihyperglycemic and antioxidant effect of the total flavones of Potentilla kleiniana Wight et Arn. in streptozotocin induced diabetic rats. Pakistan journal of pharmaceutical sciences. vol 30. issue 1. 2017-11-03. PMID:28603128. |
blood glucose levels (bgl), body weight, insulin, total cholesterol (tc), triglyceride (tg), high density lipoprotein (hdl), very low density lipoprotein (vldl), low density lipoprotein (ldl), malondialdehyde (mda), glutathione (gsh), super oxide dismutase (sod) and catalase (cat) levels of liver and pancreas were measured weekly for 4 weeks. |
2017-11-03 |
2023-08-13 |
rat |
| Henry Ginsberg, Bertrand Cariou, Trevor Orchard, Lei Chen, Junxiang Luo, Edward J Bastyr, Juliana Bue-Valleskey, Annette M Chang, Tibor Ivanyi, Scott J Jacober, Byron J Hoogwer. Lipid changes during basal insulin peglispro, insulin glargine, or NPH treatment in six IMAGINE trials. Diabetes, obesity & metabolism. vol 18. issue 11. 2017-10-31. PMID:27486125. |
the effect of both bil and glargine treatment on triglycerides (tg) depended on whether patients had been previously treated with insulin. |
2017-10-31 |
2023-08-13 |
Not clear |
| Henry Ginsberg, Bertrand Cariou, Trevor Orchard, Lei Chen, Junxiang Luo, Edward J Bastyr, Juliana Bue-Valleskey, Annette M Chang, Tibor Ivanyi, Scott J Jacober, Byron J Hoogwer. Lipid changes during basal insulin peglispro, insulin glargine, or NPH treatment in six IMAGINE trials. Diabetes, obesity & metabolism. vol 18. issue 11. 2017-10-31. PMID:27486125. |
when bil replaced conventional insulin glargine or nph treatments, increases in tg levels were observed. |
2017-10-31 |
2023-08-13 |
Not clear |
| Guilin Chen, Haijun Li, Yan Zhao, Hongyan Zhu, Enbo Cai, Yugang Gao, Shuangli Liu, He Yang, Lianxue Zhan. Saponins from stems and leaves of Panax ginseng prevent obesity via regulating thermogenesis, lipogenesis and lipolysis in high-fat diet-induced obese C57BL/6 mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 106. issue Pt A. 2017-09-27. PMID:28599882. |
the results indicate that slg showed significant anti-obesity effects in diet-induced obese mice, represented by decreased serum levels of free fatty acids (ffa), total cholesterol (tc), triglycerides (tg), low-density lipoprotein (ldl)-cholesterol, glucose, leptin and insulin, as well as a reduction in overall body and liver weight, epididymal adipose tissue weight, and food efficiency, and inhibition of abnormal increases in acyl carnitine levels normally caused by an hfd. |
2017-09-27 |
2023-08-13 |
mouse |
| Anna Veprik, Dana Laufer, Sara Weiss, Nir Rubins, Michael D Walke. GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 30. issue 11. 2017-09-21. PMID:27550964. |
gpr41 gain of function [gpr41-overexpressing transgenic (41 tg) model] and gpr41 loss of function [gpr41-knockout (ko 41) model] resulted in complementary changes in glucose tolerance, without significant effects on insulin sensitivity. |
2017-09-21 |
2023-08-13 |
mouse |
| Anna Veprik, Dana Laufer, Sara Weiss, Nir Rubins, Michael D Walke. GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 30. issue 11. 2017-09-21. PMID:27550964. |
ko 41 mice showed fasting hypoglycemia, which was consistent with increased basal and glucose-induced insulin secretion by islets in vitro mirroring this, 41 tg islets showed impaired glucose responsiveness in vitro microarray analysis of islets from 41 tg mice indicated significant alterations in gene expression patterns; several of the altered genes were chosen for further analysis and were also observed to change upon incubation of islets and cultured β-cells with scfas in a gpr41-dependent manner. |
2017-09-21 |
2023-08-13 |
mouse |
| K R Cantelli, G M Soares, R A Ribeiro, S L Balbo, C Lubaczeuski, A C Boschero, A C F Araújo, M L Bonfleu. Duodenal-jejunal bypass normalizes pancreatic islet proliferation rate and function but not hepatic steatosis in hypothalamic obese rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 50. issue 5. 2017-08-31. PMID:28380195. |
hyo sham rats were morbidly obese, insulin resistant, hypertriglyceridemic and displayed higher serum concentrations of non-esterified fatty acids (nefa) and hepatic triglyceride (tg). |
2017-08-31 |
2023-08-13 |
rat |
| Yutao Zhan, Ping Xie, Dongnian Li, Li Li, Jing Chen, Wei An, Lingqiang Zhang, Chuan Zhan. Deficiency of CKIP-1 aggravates high-fat diet-induced fatty liver in mice. Experimental cell research. vol 355. issue 1. 2017-08-21. PMID:28351752. |
here, we found: (1) ckip-1 deficient mice exhibited increased body weight, liver weight, number and size of lipid droplets, and tg content comparing with wt mice after being exposed to high fat diet (hfd); (2) the levels of serum insulin, liver glycogen, phosphorylated c-jun-n-terminal kinase-1 (pjnk1) and phosphorylated insulin receptor substrate -1(pirs1) in ckip-1 |
2017-08-21 |
2023-08-13 |
mouse |
| Nami Yamanaka, Shinichiro Saito, Noriko Osaki, Sakura Kamei, Haruo Nakamura, Yoshihisa Katsurag. Alpha-Linolenic Acid-Enriched Diacylglycerol Oil Suppresses the Postprandial Serum Triglyceride Level-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study. Journal of nutritional science and vitaminology. vol 62. issue 6. 2017-08-15. PMID:28202845. |
the suppressive effect of ala-dag on the serum tg level correlated significantly with the body mass index and fasting insulin level. |
2017-08-15 |
2023-08-13 |
human |
| Yusuke Taguchi, Yuka Toyoshima, Reiko Tokita, Hisanori Kato, Shin-Ichiro Takahashi, Shiro Minam. Triglyceride synthesis in hepatocytes isolated from rats fed a low-protein diet is enhanced independently of upregulation of insulin signaling. Biochemical and biophysical research communications. vol 490. issue 3. 2017-08-14. PMID:28647371. |
our previous studies have demonstrated that protein malnutrition upregulates insulin signaling with an increase in tg levels in rat livers. |
2017-08-14 |
2023-08-13 |
rat |
| Yusuke Taguchi, Yuka Toyoshima, Reiko Tokita, Hisanori Kato, Shin-Ichiro Takahashi, Shiro Minam. Triglyceride synthesis in hepatocytes isolated from rats fed a low-protein diet is enhanced independently of upregulation of insulin signaling. Biochemical and biophysical research communications. vol 490. issue 3. 2017-08-14. PMID:28647371. |
here, we examined whether the upregulated insulin signaling contributes to an enhancement of tg accumulation under protein malnutrition. |
2017-08-14 |
2023-08-13 |
rat |
| Yusuke Taguchi, Yuka Toyoshima, Reiko Tokita, Hisanori Kato, Shin-Ichiro Takahashi, Shiro Minam. Triglyceride synthesis in hepatocytes isolated from rats fed a low-protein diet is enhanced independently of upregulation of insulin signaling. Biochemical and biophysical research communications. vol 490. issue 3. 2017-08-14. PMID:28647371. |
the amounts of tg synthesized from both glucose and palmitate, as well as acc1 and fas protein levels, were increased at the basal state in 5c hepatocytes, but were not further increased by insulin. |
2017-08-14 |
2023-08-13 |
rat |
| Yusuke Taguchi, Yuka Toyoshima, Reiko Tokita, Hisanori Kato, Shin-Ichiro Takahashi, Shiro Minam. Triglyceride synthesis in hepatocytes isolated from rats fed a low-protein diet is enhanced independently of upregulation of insulin signaling. Biochemical and biophysical research communications. vol 490. issue 3. 2017-08-14. PMID:28647371. |
these results indicate that tg synthesis via both de novo fatty acid synthesis and esterification is enhanced in 5c hepatocytes, which is independent of the upregulation of insulin signaling. |
2017-08-14 |
2023-08-13 |
rat |
| b' H Vaverkov\\xc3\\xa1, D Kar\\xc3\\xa1sek, M Halenka, L Cib\\xc3\\xad\\xc4\\x8dkov\\xc3\\xa1, V Kub\\xc3\\xad\\xc4\\x8dkov\\xc3\\xa. Inverse association of lipoprotein (a) with markers of insulin resistance in dyslipidemic subjects. Physiological research. vol 66. issue Suppl 1. 2017-08-07. PMID:28379036.' |
lp(a) concentrations correlated inversely with tg, aip, insulin, homa, c-peptide, bmi, waist circumference, and number of ms components (p<0.01 for all). |
2017-08-07 |
2023-08-13 |
human |