| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cho-Rong Bae, Jun Hino, Hiroshi Hosoda, Mikiya Miyazato, Kenji Kangaw. C-type natriuretic peptide (CNP) in endothelial cells attenuates hepatic fibrosis and inflammation in non-alcoholic steatohepatitis. Life sciences. vol 209. 2018-09-26. PMID:30114411. |
our previous study revealed that mice transgenic for endothelial-cell-specific overexpression of cnp (e-cnp tg mice) are protected against the increased fat weight, inflammation, and insulin resistance associated with high-fat diet (hfd)-induced obesity. |
2018-09-26 |
2023-08-13 |
mouse |
| Yi Ru, Xiao Chen, Jie Xu, Lihong Huang, Miaoshan Jiang, Longhua Guo, Zhenyu Lin, Bin Qiu, Kwok-Yin Won. Hypoglycemic Effects of a Polysaccharide from Tetrastigma hemsleyanum Diels & Gilg in Alloxan-Induced Diabetic Mice. Chemistry & biodiversity. vol 15. issue 8. 2018-09-12. PMID:29806965. |
the results showed that thp could decrease the blood glucose, tc, tg, ldl-c levels, increase the body weight, hdl-c, insulin levels, and enhance the activities of antioxidant enzyme system in alloxan-induced diabetic mice. |
2018-09-12 |
2023-08-13 |
mouse |
| Zi Long, Meng Cao, Shuhao Su, Guangyuan Wu, Fansen Meng, Hao Wu, Jiangzheng Liu, Weihua Yu, Kamran Atabai, Xin Wan. Inhibition of hepatocyte nuclear factor 1b induces hepatic steatosis through DPP4/NOX1-mediated regulation of superoxide. Free radical biology & medicine. vol 113. 2018-09-10. PMID:28942246. |
overexpression of dpp4 or nox1 was associated with an increase in lipid droplets in hepatocytes and decreased expression of dpp4 or nox1 suppressed the effects of knockdown of hnf1b knockdown on triglyceride (tg) formation and insulin signaling. |
2018-09-10 |
2023-08-13 |
mouse |
| Zi Long, Meng Cao, Shuhao Su, Guangyuan Wu, Fansen Meng, Hao Wu, Jiangzheng Liu, Weihua Yu, Kamran Atabai, Xin Wan. Inhibition of hepatocyte nuclear factor 1b induces hepatic steatosis through DPP4/NOX1-mediated regulation of superoxide. Free radical biology & medicine. vol 113. 2018-09-10. PMID:28942246. |
n-acetylcysteine (nac) suppressed hnf1b knockdown-induced er stress, tg formation and insulin resistance. |
2018-09-10 |
2023-08-13 |
mouse |
| Zi Long, Meng Cao, Shuhao Su, Guangyuan Wu, Fansen Meng, Hao Wu, Jiangzheng Liu, Weihua Yu, Kamran Atabai, Xin Wan. Inhibition of hepatocyte nuclear factor 1b induces hepatic steatosis through DPP4/NOX1-mediated regulation of superoxide. Free radical biology & medicine. vol 113. 2018-09-10. PMID:28942246. |
taken together, these studies demonstrate that hnf1b plays an essential role in controlling hepatic tg homeostasis and insulin sensitivity by regulating dpp4/nox1mediated generation of superoxide. |
2018-09-10 |
2023-08-13 |
mouse |
| Tingting Tang, Xiaoyu Duan, Yu Ke, Lan Zhang, Yingbin Shen, Bin Hu, Aiping Liu, Hong Chen, Cheng Li, Wenjuan Wu, Li Shen, Yuntao Li. Antidiabetic activities of polysaccharides from Anoectochilus roxburghii and Anoectochilus formosanus in STZ-induced diabetic mice. International journal of biological macromolecules. vol 112. 2018-09-10. PMID:29438753. |
in animal experiment, after feeding with polysaccharides samples, the body weight, blood glucose, glycogen, insulin, total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), malondiadehyde (mda) and antioxidant enzyme activities in liver and kidney of mice were tested to investigate the antidiabetic activities. |
2018-09-10 |
2023-08-13 |
mouse |
| Avshalom Leibowitz, Ariel Bier, Mayan Gilboa, Edna Peleg, Iris Barshack, Ehud Grossma. Saccharin Increases Fasting Blood Glucose but Not Liver Insulin Resistance in Comparison to a High Fructose-Fed Rat Model. Nutrients. vol 10. issue 3. 2018-09-06. PMID:29534506. |
glucose, insulin, and triglycerides (tg) levels were measured upon completion. |
2018-09-06 |
2023-08-13 |
rat |
| Abolfazl Bayrami, Shadi Parvinroo, Aziz Habibi-Yangjeh, Shima Rahim Poura. Bio-extract-mediated ZnO nanoparticles: microwave-assisted synthesis, characterization and antidiabetic activity evaluation. Artificial cells, nanomedicine, and biotechnology. vol 46. issue 4. 2018-09-04. PMID:28617629. |
after treatment, fasting blood glucose (fbs), high-density lipoprotein (hdl), total triglyceride (tg), total cholesterol (tc) and insulin were measured. |
2018-09-04 |
2023-08-13 |
rat |
| Ângelo Luís, Fernanda Domingues, Luísa Pereir. Association between berries intake and cardiovascular diseases risk factors: a systematic review with meta-analysis and trial sequential analysis of randomized controlled trials. Food & function. vol 9. issue 2. 2018-08-29. PMID:29243749. |
to be included, rcts had to report 1 or more of the following outcomes: total cholesterol (tc), hdl-cholesterol (hdl), ldl-cholesterol (ldl), triglycerides (tg), blood pressure (bp), c-reactive protein (crp), tumour necrosis factor-α (tnf-α), interleukin-6 (il-6), vascular cell adhesion molecule-1 (vcam), intercellular adhesion molecule-1 (icam), glucose, insulin, apolipoprotein a-i (apo a-i) or apolipoprotein b (apo b). |
2018-08-29 |
2023-08-13 |
Not clear |
| Rector Arya, Vidya S Farook, Sharon P Fowler, Sobha Puppala, Geetha Chittoor, Roy G Resendez, Srinivas Mummidi, Jairam Vanamala, Laura Almasy, Joanne E Curran, Anthony G Comuzzie, Donna M Lehman, Christopher P Jenkinson, Jane L Lynch, Ralph A DeFronzo, John Blangero, Daniel E Hale, Ravindranath Duggirala, Vincent P Dieg. Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents. Genetic epidemiology. vol 42. issue 4. 2018-08-27. PMID:29460292. |
cmrf data included body mass index (bmi), waist circumference (wc), fat mass (fm), fasting insulin (fi), homeostasis model of assessment-insulin resistance (homa-ir), high-density lipoprotein cholesterol (hdl-c), triglycerides (tg), systolic (sbp) and diastolic (dbp) blood pressure, and number of metabolic syndrome components (msc). |
2018-08-27 |
2023-08-13 |
Not clear |
| Junqing Huang, Xiaoqi Wang, Guanyu Tao, Yuan Song, Chitang Ho, Jie Zheng, Shiyi O. Feruloylated oligosaccharides from maize bran alleviate the symptoms of diabetes in streptozotocin-induced type 2 diabetic rats. Food & function. vol 9. issue 3. 2018-08-24. PMID:29508881. |
among all the treatments, the oral administration of 600 mg per kg bw per d fos showed the best therapeutic effects on the diabetic rats by significantly lowering the levels of fasting plasma glucose (fpg), fasting insulin, tg, ldl-c, aspartate transaminase, creatine kinase and lactate dehydrogenase in plasma, while increasing the level of plasma hdl-c. |
2018-08-24 |
2023-08-13 |
rat |
| Huafeng Yin, Lihao Huang, Ting Ouyang, Lvyi Che. Baicalein improves liver inflammation in diabetic db/db mice by regulating HMGB1/TLR4/NF-κB signaling pathway. International immunopharmacology. vol 55. 2018-08-20. PMID:29223854. |
the results exhibited that ba significantly restored the blood glucose in oral glucose tolerance test (ogtt) and inhibited the levels of insulin, alanine aminotransferase (alt), aspartate aminotransaminase (ast), total cholesterol (tc) and triglyceride (tg) in c57bl/ksj-db/db mice. |
2018-08-20 |
2023-08-13 |
mouse |
| Huafeng Yin, Lihao Huang, Ting Ouyang, Lvyi Che. Baicalein improves liver inflammation in diabetic db/db mice by regulating HMGB1/TLR4/NF-κB signaling pathway. International immunopharmacology. vol 55. 2018-08-20. PMID:29223854. |
with response to palmitic acid-challenge, increased amount of insulin, alt, ast, tg, tc were observed, whereas ba pretreatment significantly restored these changes in hepg2 cells. |
2018-08-20 |
2023-08-13 |
mouse |
| Ying Zhou, Xiu-li Li, Qin Yi, Xiao-lin Zhang, Jin-ying Tian, Dong-mei Wang, Song Wu, Fei Y. [Investigating the effects of compound WS090152 on non-alcoholic fatty liver in mice]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 51. issue 6. 2018-08-16. PMID:29879345. |
the content of hepatic tg (p<0.05) and the pathological changes of the livers (p<0.01) were attenuated, insulin resistance was improved, (p<0.01), and the levels of serum tc (p<0.01) and serum tg (p<0.05) were reduced by ws090152 treatment in the mice. |
2018-08-16 |
2023-08-13 |
mouse |
| A R Jiao, H Diao, B Yu, J He, J Yu, P Zheng, Z Q Huang, Y H Luo, J Q Luo, X B Mao, D W Che. Oral administration of short chain fatty acids could attenuate fat deposition of pigs. PloS one. vol 13. issue 5. 2018-08-06. PMID:29723298. |
oral administration of scfas decreased the concentrations of triglyceride (tg), total cholesterol (tc), high density lipoprotein-cholesterol and insulin (p<0.05), and increased the leptin concentration in serum (p<0.05). |
2018-08-06 |
2023-08-13 |
Not clear |
| G K Resaland, E Aadland, A K O Nilsen, J B Bartholomew, L B Andersen, S A Andersse. The effect of a two-year school-based daily physical activity intervention on a clustered CVD risk factor score-The Sogndal school-intervention study. Scandinavian journal of medicine & science in sports. vol 28. issue 3. 2018-08-02. PMID:28759129. |
of these, 67% (171 total, 91 intervention) successfully completed both baseline and post-intervention of six cvd risk factors: systolic blood pressure (sbp), triglyceride (tg), total cholesterol-to-high-density lipoprotein cholesterol ratio (tc:hdl ratio), waist circumference (wc), the homeostasis model assessment for insulin resistance (homa), and peak oxygen uptake (vo |
2018-08-02 |
2023-08-13 |
Not clear |
| Jin-Jun Wang, Hao Jin, Shao-Ling Zheng, Peng Xia, Yong Cai, Xiao-Jie N. Phytoecdysteroids from Ajuga iva act as potential antidiabetic agent against alloxan-induced diabetic male albino rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 96. 2018-07-26. PMID:29031208. |
the present study investigated the protective effect of phytoecdysteroids extracted from the ajuga iva plant on body weight changes, blood glucose, insulin total protein, blood urea nitrogen (bun), creatinine, triglycerides (tg), cholesterol, lipid peroxidation, antioxidant enzymes, pancreatic histopathology and hexokinase-i expression in the alloxan-induced diabetic rats. |
2018-07-26 |
2023-08-13 |
rat |
| Aoxue Lu, Mengen Yu, Meng Shen, Siqi Xu, Zhengqing Xu, Yongjun Zhang, Zui Lin, Weimin Wan. Preparation of the Auricularia auricular polysaccharides simulated hydrolysates and their hypoglycaemic effect. International journal of biological macromolecules. vol 106. 2018-07-09. PMID:28847604. |
moreover, apshs could increase hepatic glycogen and pancreatic insulin level (p<0.01), as well as decrease the levels of serum tg and ldl-c compared to the diabetic control group (p<0.05). |
2018-07-09 |
2023-08-13 |
mouse |
| Z Xie, J Zhang, S Ma, X Huang, Y Huan. Effect of Chinese herbal medicine treatment on plasma lipid profile and hepatic lipid metabolism in Hetian broiler. Poultry science. vol 96. issue 6. 2018-07-06. PMID:28339712. |
in addition, the chm treatment increased plasma insulin (ins) levels and up-regulated insulin receptors (insr) glycerol-3-phosphate acyltransferase and mitochondrial and 1-acylglycerol-3-phosphate o-acyltransferase 6 mrna expression to enhance tg synthesis. |
2018-07-06 |
2023-08-13 |
Not clear |
| Li-Shan Zhou, Su-Qi Yan, Xiao-Li Xiong, Juan Huang, Ling-Ling Zhang, Jian-Qiao Tan. [Effect of Psoralea corylifolia in treating fatty liver disease in juvenal mouse by inhibiting hepatic NF-κB activation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 13. 2018-07-02. PMID:28840697. |
blood glucose (fbg, pg-1 h/2 h), blood lipid (tc, tg, hdl-c, ldl-c), fasting insulin, liver function (alt, ast) were examined. |
2018-07-02 |
2023-08-13 |
mouse |