| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A V Dontso. [THE INFLUENCE OF DEFICIT OF ENDOGENOUS NEUROPEPTIDES ON THE CLINICAL COURSE OF CORONARY HEART DISEASE]. Klinicheskaia meditsina. vol 95. issue 2. 2018-12-11. PMID:30303664. |
standard therapy resulted in a 6.5% reduction of insulin level, 9,4% , 6,1%, and 17,4% reduction of tnf-a , il-6, tg levels respectively; it increased the hdlp cholesterol level by 10,3% (p<0,05 for all values) but did not change other parameters of interest. |
2018-12-11 |
2023-08-13 |
Not clear |
| A V Dontso. [THE INFLUENCE OF DEFICIT OF ENDOGENOUS NEUROPEPTIDES ON THE CLINICAL COURSE OF CORONARY HEART DISEASE]. Klinicheskaia meditsina. vol 95. issue 2. 2018-12-11. PMID:30303664. |
dalargin therapy caused a 32,6% and 17,4%, rise in the b-endorphin and hdlp cholesterol levels but decreased leptin, insulin, cortisol, tnf-a, il-6, ldlp, and tg levels by 36,1%, 22,4%, 23,9%, 55%, 56,3%, 14% and 27,2% respectively (p<0,001). |
2018-12-11 |
2023-08-13 |
Not clear |
| Bettina Nowotny, Sabine Kahl, Birgit Klüppelholz, Barbara Hoffmann, Guido Giani, Roshan Livingstone, Peter J Nowotny, Valerie Stamm, Christian Herder, Andrea Tura, Giovanni Pacini, Jong-Hee Hwang, Michael Rode. Circulating triacylglycerols but not pancreatic fat associate with insulin secretion in healthy humans. Metabolism: clinical and experimental. vol 81. 2018-11-26. PMID:29273469. |
loss of adequate insulin secretion for the prevailing insulin resistance is critical for the development of type 2 diabetes and has been suggested to result from circulating lipids (triacylglycerols [tg] or free fatty acids) and/or adipocytokines or from ectopic lipid storage in the pancreas. |
2018-11-26 |
2023-08-13 |
Not clear |
| En-Zhong Xue, Ming-Hui Zhang, Chun-Li Li. A pilot study of the effect of ezetimibe for postprandial hyperlipidemia. Medicine. vol 97. issue 46. 2018-11-26. PMID:30431570. |
all outcomes were measured before and after 2-week treatment.after 2-week treatment, participants in the intervention group did not show better outcomes in primary endpoints of total-c, ldl-c, hdl-c, and tg; and secondary endpoints of apob-48, rlp-c, blood glucose, insulin, hba1c, and mcp, compared with subjects in the control group.the results of this study showed that ezetimibe may be not efficacious for participants with pphp after 2-week treatment. |
2018-11-26 |
2023-08-13 |
human |
| Ying-Ying Yu, Jian-Ting Cai, Zhen-Ya Song, Yu-Ling Tong, Jing-Hua Wan. The associations among Helicobacter pylori infection, white blood cell count and nonalcoholic fatty liver disease in a large Chinese population. Medicine. vol 97. issue 46. 2018-11-26. PMID:30431613. |
significant differences were found between various wbc quartiles and h pylori infection, age, gender, body mass index (bmi), systolic blood pressure (sbp), diastolic blood pressure (dbp), high-sensitivity c-reactive protein (hs-crp), glycosylated hemoglobin (hba1c), triglyceride (tg), low-density lipoprotein (ldl-c), fasting blood glucose (fpg), homeostasis model assessment of insulin resistance (homa-ir), and smoking. |
2018-11-26 |
2023-08-13 |
human |
| Xuechen Chen, Tianran Shen, Qing Li, Xu Chen, Yanping Li, Dan Li, Gengdong Chen, Wenhua Ling, Yu-Ming Che. Retinol Binding Protein-4 Levels and Non-alcoholic Fatty Liver Disease: A community-based cross-sectional study. Scientific reports. vol 7. 2018-11-14. PMID:28332619. |
the serum rbp4 levels were positively associated with the prevalence of nafld in middle-aged and elderly chinese people, and homeostatic model assessment-insulin resistance (homa-ir), trunk fat, the waist-to-hip ratio (whr), systolic blood pressure (sbp), fasting insulin, high density lipoprotein cholesterol (hdl-c) and triglycerides (tg) might be implicated in the pathogenesis of rbp4 in nafld. |
2018-11-14 |
2023-08-13 |
human |
| Zhihong Ma, Li Chu, Hongying Liu, Weijie Wang, Jieru Li, Wenzao Yao, Jianfeng Yi, Yue Ga. Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats. Scientific reports. vol 7. 2018-11-12. PMID:28300221. |
our results demonstrated that hfd resulted in hepatocellular ballooning, micro-/macrovesicular steatosis, and oxidative stress in the liver, accompanied by increased serum total cholesterol (tc), triglyceride (tg), free fatty acid (ffa), alanine aminotransferase (alt), and aspartate aminotransferase (ast) levels and homeostasis model of insulin resistance (homa-ir) index. |
2018-11-12 |
2023-08-13 |
rat |
| John R Grünberg, Jenny M Hoffmann, Shahram Hedjazifar, Annika Nerstedt, Lachmi Jenndahl, Johannes Elvin, John Castellot, Lan Wei, Sofia Movérare-Skrtic, Claes Ohlsson, Louise Mannerås Holm, Fredrik Bäckhed, Ismail Syed, Fatima Bosch, Alan Saghatelian, Barbara B Kahn, Ann Hammarstedt, Ulf Smit. Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance. Scientific reports. vol 7. 2018-11-08. PMID:28240264. |
obese tg mice remained insulin sensitive, had increased glucose uptake by adipose cells and skeletal muscle in vivo and ex vivo, increased glut4, increased chrebp and markers of adipose tissue lipogenesis. |
2018-11-08 |
2023-08-13 |
mouse |
| Maryam Tohidi, Aidin Baghbani-Oskouei, Noushin Sadat Ahanchi, Fereidoun Azizi, Farzad Hadaeg. Fasting plasma glucose is a stronger predictor of diabetes than triglyceride-glucose index, triglycerides/high-density lipoprotein cholesterol, and homeostasis model assessment of insulin resistance: Tehran Lipid and Glucose Study. Acta diabetologica. vol 55. issue 10. 2018-10-26. PMID:30066042. |
to compare the impact of triglyceride-glucose index (tyg-index), the product of fasting plasma glucose (fpg) and triglycerides (tg) with fpg, 2 h post-challenge plasma glucose (2 h-pcpg), tg/high-density lipoprotein cholesterol (tg/hdl-c), and homeostasis model assessment of insulin resistance (homa-ir) indices for prediction of type 2 diabetes (t2d) in iranian adults during a median follow-up of 12 years. |
2018-10-26 |
2023-08-13 |
Not clear |
| Sohsuke Yamada, Xin Gu. Peroxiredoxin 4 (PRDX4): Its critical in vivo roles in animal models of metabolic syndrome ranging from atherosclerosis to nonalcoholic fatty liver disease. Pathology international. vol 68. issue 2. 2018-10-25. PMID:29341349. |
we generated unique human prdx4 (hprdx4) transgenic (tg) mice on a c57bl/6j background and investigated the critical and diverse protective roles of prdx4 against diabetes mellitus, atherosclerosis, insulin resistance, and nonalcoholic fatty liver disease (nafld) as well as evaluated its role in the intestinal function in various animal models. |
2018-10-25 |
2023-08-13 |
mouse |
| Roohollah Mohseni, Zahra Arab Sadeghabadi, Mohammad Taghi Goodarzi, Maryam Teimouri, Mitra Nourbakhsh, Maryam Razzaghy Aza. Evaluation of Mn-superoxide dismutase and catalase gene expression in childhood obesity: its association with insulin resistance. Journal of pediatric endocrinology & metabolism : JPEM. vol 31. issue 7. 2018-10-25. PMID:29953407. |
also, a positive correlation was observed between the gene expression of mn-sod and cat and body mass index (bmi), fasting blood sugar, insulin resistance, low density lipoprotein-cholesterol (ldl-c) cholesterol, triglycerides (tg) and systolic blood pressure (sbp). |
2018-10-25 |
2023-08-13 |
human |
| Masaya Araki, Yoshimi Nakagawa, Asayo Oishi, Song-Iee Han, Yunong Wang, Kae Kumagai, Hiroshi Ohno, Yuhei Mizunoe, Hitoshi Iwasaki, Motohiro Sekiya, Takashi Matsuzaka, Hitoshi Shiman. The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice. International journal of molecular sciences. vol 19. issue 7. 2018-10-24. PMID:30041488. |
like fenofibrate, pemafibrate significantly suppressed hfd-induced body weight gain; decreased plasma glucose, insulin and triglyceride (tg) levels; and increased plasma fibroblast growth factor 21 (fgf21). |
2018-10-24 |
2023-08-13 |
mouse |
| Ewelina Witkowska-Sędek, Małgorzata Rumińska, Anna Stelmaszczyk-Emmel, Anna Majcher, Beata Pyrża. The associations between the growth hormone/insulin-like growth factor-1 axis, adiponectin, resistin and metabolic profile in children with growth hormone deficiency before and during growth hormone treatment. Acta biochimica Polonica. vol 65. issue 2. 2018-10-19. PMID:29913483. |
metabolic evaluation included measurements of adiponectin, resistin, igf-1, total cholesterol (total-c), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), triglycerides (tg), glucose, insulin, glycated haemoglobin (hba1c), thyroid stimulating hormone (tsh) and free thyroxine (free t4) concentrations. |
2018-10-19 |
2023-08-13 |
Not clear |
| Jun-Cheng Zhuo, Da-Ke Cai, Kai-Feng Xie, Hai-Ning Gan, Sha-Sha Li, Xue-Jun Huang, Dane Huang, Cheng-Zhe Zhang, Ru-Yue Li, Yu-Xing Chen, Xiao-Hui Zen. Mechanism of YLTZ on glycolipid metabolism based on UPLC/TOF/MS metabolomics. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 1097-1098. 2018-10-17. PMID:30241074. |
according to bio-indexes, the increased blood lipid levels, including tc, tg, ldl and fa, and the decreased hdl, the elevated glucose, reduced insulin level and impaired ogtt were observed in diabetic rat model. |
2018-10-17 |
2023-08-13 |
rat |
| Nur Ahmad Kamil Zati Iwani, Muhammad Yazid Jalaludin, Ruziana Mona Wan Mohd Zin, Md Zain Fuziah, Janet Yeow Hua Hong, Yahya Abqariyah, Abdul Halim Mokhtar, Wan Mohamud Wan Nazaimoo. Triglyceride to HDL-C Ratio is Associated with Insulin Resistance in Overweight and Obese Children. Scientific reports. vol 7. 2018-10-15. PMID:28059134. |
the purpose of this study was to investigate the usefulness of triglyceride to hdl-c ratio (tg:hdl-c) as an insulin resistance (ir) marker for overweight and obese children. |
2018-10-15 |
2023-08-13 |
Not clear |
| Nur Ahmad Kamil Zati Iwani, Muhammad Yazid Jalaludin, Ruziana Mona Wan Mohd Zin, Md Zain Fuziah, Janet Yeow Hua Hong, Yahya Abqariyah, Abdul Halim Mokhtar, Wan Mohamud Wan Nazaimoo. Triglyceride to HDL-C Ratio is Associated with Insulin Resistance in Overweight and Obese Children. Scientific reports. vol 7. 2018-10-15. PMID:28059134. |
increasing tertiles of tg:hdl-c ratio showed significant increase in mean insulin level (p = 0.03), homa-ir (p = 0.04) and significantly higher number of children with acanthosis nigricans and metabolic syndrome. |
2018-10-15 |
2023-08-13 |
Not clear |
| Xinwei Li, Yu Li, Hongyan Ding, Jihong Dong, Renhe Zhang, Dan Huang, Lin Lei, Zhe Wang, Guowen Liu, Xiaobing L. Insulin suppresses the AMPK signaling pathway to regulate lipid metabolism in primary cultured hepatocytes of dairy cows. The Journal of dairy research. vol 85. issue 2. 2018-10-15. PMID:29785900. |
these results indicate that insulin inhibits the ampkα signaling pathway to increase lipid synthesis and decrease lipid oxidation and vldl assembly in cow hepatocytes, thereby inducing tg accumulation. |
2018-10-15 |
2023-08-13 |
Not clear |
| Oluwaseun A Adeyanju, Olaniyi A Soetan, Ayodele O Soladoye, Lawrence A Olatunj. Oral hormonal therapy with ethinylestradiol-levonorgestrel improves insulin resistance, obesity, and glycogen synthase kinase-3 independent of circulating mineralocorticoid in estrogen-deficient rats. Canadian journal of physiology and pharmacology. vol 96. issue 6. 2018-10-03. PMID:29400073. |
results showed that ovx or shm + eel treated rats had increased homa-ir (homeostatic model assessment of ir), 1 h postload glucose, homa-β, triglycerides (tg), total cholesterol (tc), tc/hdl cholesterol, tg/hdl cholesterol, plasma insulin, gsk-3, corticosterone, and aldosterone. |
2018-10-03 |
2023-08-13 |
rat |
| Xiaolei Hu, Dongsheng Yu, Langen Zhuang, Mengyun Zhou, Zhaoming Shi, Guoxi Jin, Xiaomei Zhan. Geniposide improves hepatic inflammation in diabetic db/db mice. International immunopharmacology. vol 59. 2018-10-03. PMID:29655055. |
the oral glucose tolerance test was performed, and the levels of insulin, alanine aminotransferase (alt), aspartate aminotransaminase (ast), total cholesterol (tc) and triglyceride (tg) were determined. |
2018-10-03 |
2023-08-13 |
mouse |
| Mincheol Kang, Jain Jeong, Jinhee Lee, Song Park, Yonghun Sung, Minjee Choi, Wookbong Kwon, Soyoung Jang, Kwang Shik Choi, Yeon Sik Choo, Duhak Yoon, Myoung Ok Kim, Zae Young Ryo. Placental growth factor (PlGF) is linked to inflammation and metabolic disorders in mice with diet-induced obesity. Endocrine journal. vol 65. issue 4. 2018-10-02. PMID:29434073. |
therefore, to verify the possible link of diet-induced obesity (dio) with inflammation and related metabolic disorders, such as insulin resistance, we fed high-fat diet (hfd) to tg mice for 16 weeks. |
2018-10-02 |
2023-08-13 |
mouse |