| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun Fan, Chunlan Zhang, Jin B. Relationship between Selected Serum Metallic Elements and Obesity in Children and Adolescent in the U.S. Nutrients. vol 9. issue 2. 2017-07-31. PMID:28165362. |
blood lead, mercury, selenium, manganese, copper, and zinc, as well as biochemical parameters including triglyceride (tg), cholesterol, low-density lipoprotein (ldl), and homeostasis model assessment of insulin resistance (homa-ir) were assessed for all subjects. |
2017-07-31 |
2023-08-13 |
human |
| Mehrnoosh Shanaki, Reza Fadaei, Nariman Moradi, Solaleh Emamgholipour, Hossein Poustch. The Circulating CTRP13 in Type 2 Diabetes and Non-Alcoholic Fatty Liver Patients. PloS one. vol 11. issue 12. 2017-07-11. PMID:27936230. |
ctrp13 had significant negative correlation with unfavorable anthropometric and metabolic factors including bmi, visceral fat, insulin, homa-ir, tg, ast, alt and ɣ-gt and have a positive correlation with plasma concentration of adiponectin. |
2017-07-11 |
2023-08-13 |
Not clear |
| Shujun Zhang, Tingting Du, Mengni Li, Jing Jia, Huiming Lu, Xuan Lin, Xuefeng Y. Triglyceride glucose-body mass index is effective in identifying nonalcoholic fatty liver disease in nonobese subjects. Medicine. vol 96. issue 22. 2017-06-30. PMID:28562560. |
triglyceride (tg) and glucose index combined with body mass index (tyg-bmi) has been proposed as a favorable marker of insulin resistance. |
2017-06-30 |
2023-08-13 |
human |
| Anantha Metlakunta, Wan Huang, Maja Stefanovic-Racic, Nikolaos Dedousis, Ian Sipula, Robert M O'Dohert. Kupffer cells facilitate the acute effects of leptin on hepatic lipid metabolism. American journal of physiology. Endocrinology and metabolism. vol 312. issue 1. 2017-06-20. PMID:27827807. |
notably, liver tg were elevated in both lean and obese myeloid cell obr, but the degree of obesity and insulin resistance induced by a high-fat diet was similar to control mice. |
2017-06-20 |
2023-08-13 |
mouse |
| Alejandro Gugliucc. Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance. Medical hypotheses. vol 93. 2017-06-15. PMID:27372863. |
fructose may be a key contributor to the biochemical alterations which promote the metabolic syndrome (mets), non-alcoholic fatty liver disease (nafld) and type 2 diabetes (t2dm): (a) its consumption in all forms but especially in liquid form has much increased alongside with incidence of mets conditions; (b) it is metabolized almost exclusively in the liver, where it stimulates de novo lipogenesis to drive hepatic triglyceride (tg) synthesis which (c) contributes to hepatic insulin resistance and nafld (lustig et al., 2015; weiss et al., 2013; lim et al., 2010; schwarzet al., 2015; stanhope et al., 2009, 2013) [1-6]. |
2017-06-15 |
2023-08-13 |
Not clear |
| Sheo B Singh, Ling Kang, Andrea R Nawrocki, Dan Zhou, Margaret Wu, Stephen Previs, Corey Miller, Haiying Liu, Catherine D G Hines, Maria Madeira, Jin Cao, Kithsiri Herath, Larry D Spears, Clay F Semenkovich, Liangsu Wang, David E Kelley, Cai Li, Hong-Ping Gua. The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys. PloS one. vol 11. issue 10. 2017-06-15. PMID:27695056. |
recently, we reported that oral administration of ptm in mouse models (db/db and db/+) with high de novo lipogenesis (dnl) tone inhibited dnl and enhanced glucose oxidation, which in turn led to net reduction of liver triglycerides (tg), reduced ambient glucose, and improved insulin sensitivity. |
2017-06-15 |
2023-08-13 |
mouse |
| Laura D Ratner, Guillermina Stevens, Maria Marta Bonaventura, Victoria A Lux-Lantos, Matti Poutanen, Ricardo S Calandra, Ilpo T Huhtaniemi, Susana B Rull. Hyperprolactinemia induced by hCG leads to metabolic disturbances in female mice. The Journal of endocrinology. vol 230. issue 1. 2017-06-13. PMID:27154336. |
tg female mice showed hyperinsulinemia, hypertriglyceridemia, and dyslipidemia, as well as glucose intolerance and insulin resistance at 6 months of age. |
2017-06-13 |
2023-08-13 |
mouse |
| Guangming Gong, Haipo Yuan, Ya Liu, Luguang Q. Investigation of the Effects and Mechanisms of Mai Tong Formula on Lower Limb Macroangiopathy in a Spontaneous Diabetic Rat Model. Journal of diabetes research. vol 2016. 2017-06-06. PMID:27995148. |
we found that mtf treatment significantly reduced serum fasting blood glucose (fbg), triglycerides (tg), total cholesterol (tc), il6, and vegf and increased serum insulin in this model. |
2017-06-06 |
2023-08-13 |
rat |
| Yajie Guo, Junjie Yu, Jiali Deng, Bin Liu, Yuzhong Xiao, Kai Li, Fei Xiao, Feixiang Yuan, Yong Liu, Shanghai Chen, Feifan Gu. A Novel Function of Hepatic FOG2 in Insulin Sensitivity and Lipid Metabolism Through PPARα. Diabetes. vol 65. issue 8. 2017-06-05. PMID:27207553. |
moreover, the improved insulin sensitivity and increased hepatic tg accumulation by ad-shfog2 were largely reversed by adenovirus-expressing pparα (ad-pparα) in wt mice. |
2017-06-05 |
2023-08-13 |
mouse |
| Yajie Guo, Junjie Yu, Jiali Deng, Bin Liu, Yuzhong Xiao, Kai Li, Fei Xiao, Feixiang Yuan, Yong Liu, Shanghai Chen, Feifan Gu. A Novel Function of Hepatic FOG2 in Insulin Sensitivity and Lipid Metabolism Through PPARα. Diabetes. vol 65. issue 8. 2017-06-05. PMID:27207553. |
finally, we generated fog2 liver-specific knockout mice and found that they exhibit enhanced insulin sensitivity and elevated hepatic tg accumulation, which were also reversed by ad-pparα. |
2017-06-05 |
2023-08-13 |
mouse |
| Sayaka Katagiri, Kyoungmin Park, Yasutaka Maeda, Tata Nageswara Rao, Mogher Khamaisi, Qian Li, Hisashi Yokomizo, Akira Mima, Luca Lancerotto, Amy Wagers, Dennis P Orgill, George L Kin. Overexpressing IRS1 in Endothelial Cells Enhances Angioblast Differentiation and Wound Healing in Diabetes and Insulin Resistance. Diabetes. vol 65. issue 9. 2017-06-05. PMID:27217486. |
gt in hf-fed diabetic mice exhibited parallel decreases in insulin and vegf-induced pakt and ec numbers by >50% without changes in angioblasts versus wt mice, which were improved in ecirs1 tg mice on normal chow or hf diet. |
2017-06-05 |
2023-08-13 |
mouse |
| Thomas Scherer, Claudia Lindtner, James O'Hare, Martina Hackl, Elizabeth Zielinski, Angelika Freudenthaler, Sabina Baumgartner-Parzer, Klaus Tödter, Joerg Heeren, Martin Krššák, Ludger Scheja, Clemens Fürnsinn, Christoph Buettne. Insulin Regulates Hepatic Triglyceride Secretion and Lipid Content via Signaling in the Brain. Diabetes. vol 65. issue 6. 2017-06-01. PMID:26861781. |
here, we show that in conscious, unrestrained male sprague dawley rats the infusion of insulin into the third ventricle acutely increased hepatic tg secretion. |
2017-06-01 |
2023-08-13 |
mouse |
| Jami M Gurley, Olga Ilkayeva, Robert M Jackson, Beth A Griesel, Phillip White, Satochi Matsuzaki, Rizwan Qaisar, Holly Van Remmen, Kenneth M Humphries, Christopher B Newgard, Ann Louise Olso. Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism. Diabetes. vol 65. issue 12. 2017-05-31. PMID:27679559. |
previously, we demonstrated that transgenic mice engineered to express the human glut4 gene under the control of the human glut4 promoter (i.e., transgenic [tg] mice) are resistant to obesity-induced insulin resistance. |
2017-05-31 |
2023-08-13 |
mouse |
| H H Wang, Q F Wan. Low vaspin levels are related to endothelial dysfunction in patients with ankylosing spondylitis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 49. issue 7. 2017-05-26. PMID:27383120. |
univariate analysis showed a correlation between vaspin and fmd (r=0.73, p=0.003), low-density lipoprotein cholesterol (r=-0.45, p=0.033), high-density lipoprotein cholesterol (r=0.63, p=0.025), fasting blood glucose (r=-0.79, p=0.006), triglycerides (tg) (r=-0.68, p=0.036), systolic blood pressure (r=-0.35, p=0.021), c-reactive protein (r=-0.67, p=0.011), homeostatic model assessment of insulin resistance (homa-ir) (r=-0.77, p=0.023) and erythrocyte sedimentation rate (r=-0.88, p=0.039) in patients. |
2017-05-26 |
2023-08-13 |
human |
| Yuanyuan Luo, Hua Qu, Hang Wang, Huili Wei, Jing Wu, Yang Duan, Dan Liu, Huacong Den. Plasma Periostin Levels Are Increased in Chinese Subjects with Obesity and Type 2 Diabetes and Are Positively Correlated with Glucose and Lipid Parameters. Mediators of inflammation. vol 2016. 2017-05-15. PMID:27313402. |
correlation analysis showed that plasma periostin levels were positively correlated with weight, waist circumference (wc), body mass index (bmi), waist-hip ratio (whr), fasting plasma glucose (fpg), 2 h postchallenge plasma glucose (2 h pg), glycated hemoglobin (hba1c), triglyceride (tg), total cholesterol (tc), fasting insulin (fins), homeostasis model assessment of insulin resistance (homa-ir), tnf-α, and il-6 (p < 0.05 or 0.001) and negatively correlated with high-density lipoprotein cholesterol (hdl-c) (p < 0.001). |
2017-05-15 |
2023-08-13 |
human |
| Yuanyuan Luo, Hua Qu, Hang Wang, Huili Wei, Jing Wu, Yang Duan, Dan Liu, Huacong Den. Plasma Periostin Levels Are Increased in Chinese Subjects with Obesity and Type 2 Diabetes and Are Positively Correlated with Glucose and Lipid Parameters. Mediators of inflammation. vol 2016. 2017-05-15. PMID:27313402. |
plasma periostin levels were strongly associated with plasma tg, chronic inflammation, and insulin resistance. |
2017-05-15 |
2023-08-13 |
human |
| G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metge. Acute effects of general anesthesia with propofol, pentobarbital or isoflurane plus propofol on plasma metabolites and hormones in adult pigs. Journal of animal science. vol 94. issue 12. 2017-05-08. PMID:28046175. |
six-h profiles of glucose, lactate, non-esterified fatty acids (nefa), triglycerides (tg), cholesterol, urea as well as hormones including glucagon, insulin and cortisol were determined. |
2017-05-08 |
2023-08-13 |
Not clear |
| Yanjin Hu, Jia Liu, Xuejie Dong, Yuan Xu, Song Leng, Guang Wan. Clinical Study of Serum Homocysteine and Non-Alcoholic Fatty Liver Disease in Euglycemic Patients. Medical science monitor : international medical journal of experimental and clinical research. vol 22. 2017-05-03. PMID:27803497. |
results the nafld group had significantly higher hcy level (13.78±5.84 vs. 11.96±3.58 mmol/l, p<0.001), as well as higher body mass index (bmi), total cholesterol (tc), low density lipoprotein cholesterol (ldl-c), triglyceride (tg), glutamic-pyruvic transaminase (alt), glutamic-oxalacetic transaminase (ast), fasting plasma glucose (fpg), fasting insulin (fins), homeostasis model assessment for insulin resistance (homa-ir), homeostasis model assessment for beta cell function (homa-b), and lower high density lipoprotein cholesterol (hdl-c). |
2017-05-03 |
2023-08-13 |
Not clear |
| Akihiro Nakamura, Yuto Monma, Shoko Kajitani, Kazuki Noda, Sota Nakajima, Hideaki Endo, Tohru Takahashi, Eiji Nozak. Effect of glycemic state on postprandial hyperlipidemia and hyperinsulinemia in patients with coronary artery disease. Heart and vessels. vol 31. issue 9. 2017-04-24. PMID:26439243. |
the aucs of serum tg or rlp-c levels showed a correlation with the aucs of plasma insulin (auc-tg, r = 0.5437, p < 0.0001; auc-rlp-c, r = 0.6847, p < 0.0001), and they correlated well with the insulin resistance index (auc-tg, r = 0.7724, p < 0.0001; auc-rlp-c, r = 0.7645, p < 0.0001). |
2017-04-24 |
2023-08-13 |
Not clear |
| İlknur Bingül, A Fatih Aydın, Canan Başaran-Küçükgergin, Işın Doğan-Ekici, Jale Çoban, Semra Doğru-Abbasoğlu, Müjdat Uysa. High-fat diet plus carbon tetrachloride-induced liver fibrosis is alleviated by betaine treatment in rats. International immunopharmacology. vol 39. 2017-04-17. PMID:27494683. |
serum liver function tests and tumor necrosis factor-α, insulin resistance, hepatic triglyceride (tg) and hydroxyproline (hyp) levels and oxidative stress parameters were determined along with histopathologic observations. |
2017-04-17 |
2023-08-13 |
rat |