| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Bolaffi, G Rodd, Y H Ma, G M Grodsk. Effect of glucagon or somatostatin on desensitized insulin secretion. Endocrinology. vol 126. issue 3. 1990-04-05. PMID:1968383. |
results show that 1) islet release of glucagon and somatostatin desensitizes during constant stimulation; and 2) islet release of insulin desensitizes to chronic potentiation or inhibition, respectively, by these hormones. |
1990-04-05 |
2023-08-11 |
rat |
| J L Bolaffi, G Rodd, Y H Ma, G M Grodsk. Effect of glucagon or somatostatin on desensitized insulin secretion. Endocrinology. vol 126. issue 3. 1990-04-05. PMID:1968383. |
furthermore, 3) changing b-cell sensitivity to either glucagon or somatostatin cannot account for observed desensitization of insulin secretion with chronic glucose exposure. |
1990-04-05 |
2023-08-11 |
rat |
| D W Gra. Islet isolation and transplantation techniques in the primate. Surgery, gynecology & obstetrics. vol 170. issue 3. 1990-03-29. PMID:2106172. |
cells secreting insulin, glucagon and somatostatin were present in approximately normal proportions. |
1990-03-29 |
2023-08-11 |
monkey |
| P O Schwille, G Rümenapf, R Köhle. Blood levels of glucometabolic hormones and urinary saturation with stone forming phases after an oral test meal in male patients with recurrent idiopathic calcium urolithiasis and in healthy controls. Journal of the American College of Nutrition. vol 8. issue 6. 1990-03-21. PMID:2576028. |
however, serum insulin was significantly elevated in i-hc versus c, but serum c-peptide, plasma glucagon, and somatostatin levels were comparable in rcu and c. ffa were significantly lower in rcu than c. postprandial phosphaturia and urinary saturation with ca-phosphates were significantly higher in rcu versus c, whereas urinary camp, ph, and oxalate were similar. |
1990-03-21 |
2023-08-11 |
Not clear |
| J Fowelin, S Attvall, H Von Schenck, U Smith, I Lage. Combined effect of growth hormone and cortisol on late posthypoglycemic insulin resistance in humans. Diabetes. vol 38. issue 11. 1990-03-16. PMID:2576005. |
infusion of propranolol did not prevent insulin resistance, whereas somatostatin partially prevented its appearance. |
1990-03-16 |
2023-08-11 |
human |
| J Fowelin, S Attvall, H Von Schenck, U Smith, I Lage. Combined effect of growth hormone and cortisol on late posthypoglycemic insulin resistance in humans. Diabetes. vol 38. issue 11. 1990-03-16. PMID:2576005. |
somatostatin plus metyrapone completely normalized posthypoglycemic insulin resistance. |
1990-03-16 |
2023-08-11 |
human |
| M Allon, M Rodriguez, F Llac. Insulin in the acute renal adaptation to dietary phosphate restriction in the rat. Kidney international. vol 37. issue 1. 1990-03-12. PMID:1967663. |
group a received a normal (0.8%) phosphate meal, followed by saline infusion; group b, a low (0.03%) phosphate meal, followed by saline infusion; group c, a low phosphate meal, followed by infusion of somatostatin to suppress endogenous insulin secretion; and group d, a low phosphate meal, followed by infusion of somatostatin plus insulin. |
1990-03-12 |
2023-08-11 |
rat |
| D Leenanuruksa, P Niumsup, G H McDowel. Insulin affects glucose uptake by muscle and mammary tissues of lactating ewes. Australian journal of biological sciences. vol 41. issue 4. 1990-03-07. PMID:2908423. |
insulin secretion was suppressed by a primed/continuous infusion of somatostatin, then insulin was administered by continuous intravenous infusion of doses that were increased, in a step-wise manner, from 0 to 2 u h-1. |
1990-03-07 |
2023-08-11 |
Not clear |
| D Leenanuruksa, P Niumsup, G H McDowel. Insulin affects glucose uptake by muscle and mammary tissues of lactating ewes. Australian journal of biological sciences. vol 41. issue 4. 1990-03-07. PMID:2908423. |
somatostatin suppressed but did not completely inhibit insulin secretion as shown by maintenance of plasma concentration of c-peptide. |
1990-03-07 |
2023-08-11 |
Not clear |
| L T Ho, Z Y Chang, J T Wang, S H Li, Y F Liu, Y D Chen, G M Reave. Insulin insensitivity in offspring of parents with type 2 diabetes mellitus. Diabetic medicine : a journal of the British Diabetic Association. vol 7. issue 1. 1990-03-05. PMID:1967567. |
in addition, in vivo insulin action was estimated by determining the steady-state plasma glucose concentration during a 3-h continuous infusion of glucose, insulin, and somatostatin. |
1990-03-05 |
2023-08-11 |
human |
| K S Rastogi, L Lickley, M Jokay, S Efendic, M Vrani. Paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia. Endocrinology. vol 126. issue 2. 1990-03-05. PMID:1967577. |
paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia. |
1990-03-05 |
2023-08-11 |
Not clear |
| K S Rastogi, L Lickley, M Jokay, S Efendic, M Vrani. Paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia. Endocrinology. vol 126. issue 2. 1990-03-05. PMID:1967577. |
normoglycemia 1) normalizes somatostatin content, 2) further diminishes insulin and proinsulin synthesis presumably due to lack of hyperglycemic stimulus, and 3) paradoxically decreases pancreatic glucagon content 5-fold below its normal level. |
1990-03-05 |
2023-08-11 |
Not clear |
| J Srinivasappa, D M Asher, K L Pomeroy, L J Murphy, A V Wolff, J W Yoon, D C Gajdusek, A L Notkin. Scrapie-induced diabetes mellitus in hamsters. Microbial pathogenesis. vol 7. issue 3. 1990-03-05. PMID:2693886. |
histological examination of the pancreas revealed no morphological changes in infected animals with no alteration in distribution of cells secreting insulin, glucagon and somatostatin. |
1990-03-05 |
2023-08-11 |
Not clear |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
the effects of electrical stimulation of the left splanchnic nerve on insulin, somatostatin, and glucagon secretion from the isolated perfused rat pancreas were investigated. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
both insulin and somatostatin output in the presence of 16.7 mm glucose were inhibited during sns by 85 and 56% of the basal value, respectively. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
perfusion with 10(-6) m propranolol further decreased insulin and somatostatin output during sns, when expressed as the total decrement beneath basal during stimulation. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
however, 10(-6) m phentolamine (phe) attenuated the sns-induced inhibition of insulin and somatostatin output by 50 and 40%, respectively. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
with 10(-6) m phe plus 10(-6) m propranolol, insulin and somatostatin output remained decreased after sns. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
these results suggest that insulin and somatostatin secretions induced by glucose are inhibited during sns through the alpha-adrenergic mechanism and also that the beta-adrenergic mechanism exerts a stimulatory action. |
1990-03-01 |
2023-08-11 |
rat |