| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Fowelin, S Attvall, H Von Schenck, U Smith, I Lage. Combined effect of growth hormone and cortisol on late posthypoglycemic insulin resistance in humans. Diabetes. vol 38. issue 11. 1990-03-16. PMID:2576005. |
somatostatin plus metyrapone completely normalized posthypoglycemic insulin resistance. |
1990-03-16 |
2023-08-11 |
human |
| M Allon, M Rodriguez, F Llac. Insulin in the acute renal adaptation to dietary phosphate restriction in the rat. Kidney international. vol 37. issue 1. 1990-03-12. PMID:1967663. |
group a received a normal (0.8%) phosphate meal, followed by saline infusion; group b, a low (0.03%) phosphate meal, followed by saline infusion; group c, a low phosphate meal, followed by infusion of somatostatin to suppress endogenous insulin secretion; and group d, a low phosphate meal, followed by infusion of somatostatin plus insulin. |
1990-03-12 |
2023-08-11 |
rat |
| D Leenanuruksa, P Niumsup, G H McDowel. Insulin affects glucose uptake by muscle and mammary tissues of lactating ewes. Australian journal of biological sciences. vol 41. issue 4. 1990-03-07. PMID:2908423. |
insulin secretion was suppressed by a primed/continuous infusion of somatostatin, then insulin was administered by continuous intravenous infusion of doses that were increased, in a step-wise manner, from 0 to 2 u h-1. |
1990-03-07 |
2023-08-11 |
Not clear |
| D Leenanuruksa, P Niumsup, G H McDowel. Insulin affects glucose uptake by muscle and mammary tissues of lactating ewes. Australian journal of biological sciences. vol 41. issue 4. 1990-03-07. PMID:2908423. |
somatostatin suppressed but did not completely inhibit insulin secretion as shown by maintenance of plasma concentration of c-peptide. |
1990-03-07 |
2023-08-11 |
Not clear |
| L T Ho, Z Y Chang, J T Wang, S H Li, Y F Liu, Y D Chen, G M Reave. Insulin insensitivity in offspring of parents with type 2 diabetes mellitus. Diabetic medicine : a journal of the British Diabetic Association. vol 7. issue 1. 1990-03-05. PMID:1967567. |
in addition, in vivo insulin action was estimated by determining the steady-state plasma glucose concentration during a 3-h continuous infusion of glucose, insulin, and somatostatin. |
1990-03-05 |
2023-08-11 |
human |
| K S Rastogi, L Lickley, M Jokay, S Efendic, M Vrani. Paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia. Endocrinology. vol 126. issue 2. 1990-03-05. PMID:1967577. |
paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia. |
1990-03-05 |
2023-08-11 |
Not clear |
| K S Rastogi, L Lickley, M Jokay, S Efendic, M Vrani. Paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia. Endocrinology. vol 126. issue 2. 1990-03-05. PMID:1967577. |
normoglycemia 1) normalizes somatostatin content, 2) further diminishes insulin and proinsulin synthesis presumably due to lack of hyperglycemic stimulus, and 3) paradoxically decreases pancreatic glucagon content 5-fold below its normal level. |
1990-03-05 |
2023-08-11 |
Not clear |
| J Srinivasappa, D M Asher, K L Pomeroy, L J Murphy, A V Wolff, J W Yoon, D C Gajdusek, A L Notkin. Scrapie-induced diabetes mellitus in hamsters. Microbial pathogenesis. vol 7. issue 3. 1990-03-05. PMID:2693886. |
histological examination of the pancreas revealed no morphological changes in infected animals with no alteration in distribution of cells secreting insulin, glucagon and somatostatin. |
1990-03-05 |
2023-08-11 |
Not clear |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
the effects of electrical stimulation of the left splanchnic nerve on insulin, somatostatin, and glucagon secretion from the isolated perfused rat pancreas were investigated. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
both insulin and somatostatin output in the presence of 16.7 mm glucose were inhibited during sns by 85 and 56% of the basal value, respectively. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
perfusion with 10(-6) m propranolol further decreased insulin and somatostatin output during sns, when expressed as the total decrement beneath basal during stimulation. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
however, 10(-6) m phentolamine (phe) attenuated the sns-induced inhibition of insulin and somatostatin output by 50 and 40%, respectively. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
with 10(-6) m phe plus 10(-6) m propranolol, insulin and somatostatin output remained decreased after sns. |
1990-03-01 |
2023-08-11 |
rat |
| T Kurose, Y Seino, S Nishi, K Tsuji, T Taminato, K Tsuda, H Imur. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:1689116. |
these results suggest that insulin and somatostatin secretions induced by glucose are inhibited during sns through the alpha-adrenergic mechanism and also that the beta-adrenergic mechanism exerts a stimulatory action. |
1990-03-01 |
2023-08-11 |
rat |
| N Edwin, C M Leig. Immunocytochemical study of the endocrine pancreas in the grey kangaroo (Macropus fuliginosus). Cell and tissue research. vol 259. issue 1. 1990-03-01. PMID:1967553. |
semithin plastic sections were stained individually with primary antibodies for insulin, glucagon, somatostatin and pancreatic polypeptide (pp), and then photographed. |
1990-03-01 |
2023-08-11 |
Not clear |
| P Castellino, L Luzi, S Del Prato, R A DeFronz. Dissociation of the effects of epinephrine and insulin on glucose and protein metabolism. The American journal of physiology. vol 258. issue 1 Pt 1. 1990-03-01. PMID:2105656. |
subjects participated in four experimental protocols: 1) euglycemic insulin clamp (+80 microu/ml), 2) epinephrine infusion (50 ng.kg-1.min-1) plus somatostatin with basal replacement of insulin and glucagon, 3) combined epinephrine (50 ng.kg-1.min-1) plus insulin (+80 microu/ml) infusion, and 4) epinephrine and somatostatin as in study 2 plus basal amino acid replacement. |
1990-03-01 |
2023-08-11 |
human |
| L M Karabatas, M Arata, O H Pivetta, J C Basab. Glucagon secretion and alpha-cell sensitivity to somatostatin in genetically diabetic mice C57BL/KsJ-mdb. Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia. vol 39. issue 2. 1990-02-26. PMID:2575840. |
in previous studies in c57bl/ksj mdb/mdb mice, we observed alterations in glucose-induced insulin secretion in vitro, and a defective inhibitory effect of somatostatin on insulin secretion. |
1990-02-26 |
2023-08-11 |
mouse |
| O Segers, G Somer. Effect of rioprostil, a methylprostaglandin E1 analog, on basal and stimulated plasma pancreatic hormone levels in man. Digestive diseases and sciences. vol 35. issue 1. 1990-02-16. PMID:2104796. |
treatment with rioprostil remained without effect on mixed meal-induced changes in plasma glucose levels and concomitant increases in insulin, pancreatic polypeptide, and somatostatin levels. |
1990-02-16 |
2023-08-11 |
human |
| O Segers, G Somer. Effect of rioprostil, a methylprostaglandin E1 analog, on basal and stimulated plasma pancreatic hormone levels in man. Digestive diseases and sciences. vol 35. issue 1. 1990-02-16. PMID:2104796. |
it is concluded that in healthy individuals rioprostil influences the basal and glucose-induced levels of glucagon, insulin, and somatostatin. |
1990-02-16 |
2023-08-11 |
human |