Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D Bretherton-Watt, M A Ghatei, S Legon, H Jamal, K Suda, S R Bloo. Depletion of islet amyloid polypeptide in the spontaneously diabetic (BB) Wistar rat. Journal of molecular endocrinology. vol 6. issue 1. 1991-05-23. PMID:2015054. |
insulin mrna was dramatically reduced to only 4% of the control group and, in contrast, somatostatin was relatively unaffected, with the diabetic group retaining 86% of signal compared with the controls. |
1991-05-23 |
2023-08-11 |
rat |
R P Robertson, E R Seaquist, T F Walset. G proteins and modulation of insulin secretion. Diabetes. vol 40. issue 1. 1991-05-22. PMID:1901807. |
gi mediates decreases in intracellular camp caused by inhibitors of insulin secretion, e.g., epinephrine, somatostatin, prostaglandin e2, and galanin. |
1991-05-22 |
2023-08-11 |
Not clear |
B Agerberth, C G Ostenson, S Efendic, H Jörnval. Pancreatic secretory trypsin inhibitor (PSTI) isolated from pig intestine. Influence on insulin and somatostatin release. FEBS letters. vol 281. issue 1-2. 1991-05-21. PMID:1673102. |
influence on insulin and somatostatin release. |
1991-05-21 |
2023-08-11 |
rat |
B Agerberth, C G Ostenson, S Efendic, H Jörnval. Pancreatic secretory trypsin inhibitor (PSTI) isolated from pig intestine. Influence on insulin and somatostatin release. FEBS letters. vol 281. issue 1-2. 1991-05-21. PMID:1673102. |
continuing this study we found a polypeptide, which inhibited glucose-induced insulin release but enhanced glucose-induced somatostatin secretion. |
1991-05-21 |
2023-08-11 |
rat |
H Azuma, K Zeki, Y Tanaka, H Suzuki, U Yamashita, I Morimoto, S Et. Inhibitory effect of IL-1 on the TSH dependent growth of rat thyroid cells (FRTL-5). Endocrinologia japonica. vol 37. issue 5. 1991-05-17. PMID:2128271. |
in 5h medium, namely coon's modified ham's f-12 medium supplemented with 5% calf serum and a five-hormone preparation consisting of insulin, hydrocortisone, transferrin, glycyl-l-histidyl-l-lysine acetate and somatostatin, il-1 enhanced the growth of frtl-5 cells detected by [3h]tdr incorporation. |
1991-05-17 |
2023-08-11 |
rat |
Y Kuroda, Y Suzuki, T Kawamura, H Fujiwara, Y Fujino, K Yamamoto, Y Saito. The long-term function and histology of segmental pancreatic autografts with pancreatic exocrine diversion to the esophagus in dogs. The Japanese journal of surgery. vol 20. issue 6. 1991-05-16. PMID:2084292. |
histological studies of the autografts done three years after the transplantation showed almost normal pancreatic architecture in the islets and exocrine tissues, while histochemical analysis with immunoperoxidase stains confirmed the presence of insulin, glucagon and somatostatin. |
1991-05-16 |
2023-08-11 |
dog |
J Yamada, W J Krause, N Edwin, T Mochizuki, N Yanaihar. A survey of endocrine cells in the pancreas of the echidna (Tachyglossus aculeatus) with special reference to pancreatic motilin cells. Journal of anatomy. vol 171. 1991-05-09. PMID:1981999. |
immunoreactive endocrine cells were observed using antisera to insulin, glucagon, somatostatin, avian pancreatic polypeptide and bovine pancreatic polypeptide. |
1991-05-09 |
2023-08-11 |
cattle |
R P Robertson, G Gromo, H J Zhang, T F Walseth, L Inverard. Dysregulated release and degradation of insulin during mononuclear cell-induced beta-cell lysis in HIT cells. Diabetes. vol 40. issue 4. 1991-05-06. PMID:1672658. |
somatostatin did not inhibit the early exaggerated insulin release, suggesting that these increased insulin levels represented leakage of insulin from damaged hit cells rather than functional insulin secretion. |
1991-05-06 |
2023-08-11 |
human |
T Barreca, R Franceschini, A Cataldi, E Roland. Plasma somatostatin response to an oral mixed test meal in cirrhotic patients. Journal of hepatology. vol 12. issue 1. 1991-04-30. PMID:1672540. |
plasma somatostatin, blood glucose, plasma insulin, c-peptide and glucagon were determined before and 15, 30, 45, 60, 90, 120 and 180 min after the start of the meal. |
1991-04-30 |
2023-08-11 |
human |
H Toshimori, R Narita, M Nakazato, J Asai, T Mitsukawa, K Kangawa, H Matsuo, S Matsukur. Islet amyloid polypeptide (IAPP) in the gastrointestinal tract and pancreas of man and rat. Cell and tissue research. vol 262. issue 3. 1991-04-30. PMID:2078850. |
an examination was made for evidence of colocalization of iapp-immunoreactive material with material immunoreactive for gastrin, somatostatin, vasoactive intestinal polypeptide, pancreatic polypeptide, insulin, and glucagon, but none was found. |
1991-04-30 |
2023-08-11 |
human |
F Guerino, G B Huntington, R A Erdman, T H Elsasser, C K Reynold. The effects of abomasal casein infusions in growing beef steers on portal and hepatic flux of pancreatic hormones and arterial concentrations of somatomedin-C. Journal of animal science. vol 69. issue 1. 1991-04-25. PMID:2005031. |
the net release of insulin, glucagon and somatostatin by the portal-drained viscera (pdv) and their net uptake by the liver in response to 3-d abomasal infusions of casein were measured in seven multicatheterized beef steers. |
1991-04-25 |
2023-08-11 |
Not clear |
L K Bachrach, M C Eggo, G N Burrow, F Liu, T Tram, D R Powel. Regulation of insulin-like growth factor-binding protein messenger ribonucleic acid levels in sheep thyroid cells. Endocrinology. vol 128. issue 4. 1991-04-23. PMID:1706262. |
cells grown in basal medium or with six-hormone (6h) medium supplements (transferrin, glycyl-histidyl-lysine, hydrocortisone, somatostatin, insulin, and tsh) release nonglycosylated bps that migrate at 24, 27, 29, and 32 kda on western ligand blot. |
1991-04-23 |
2023-08-11 |
rat |
H C Fehmann, J F Habene. Functional receptors for the insulinotropic hormone glucagon-like peptide-I(7-37) on a somatostatin secreting cell line. FEBS letters. vol 279. issue 2. 1991-04-17. PMID:1672112. |
insulin secretion from perifused b cells was stimulated by glp-i(7-37) (maximum at 10 nmol/l) and 10 nmol/l glp-i(7-37) released somatostatin from perifused d cells. |
1991-04-17 |
2023-08-11 |
Not clear |
H C Fehmann, J F Habene. Functional receptors for the insulinotropic hormone glucagon-like peptide-I(7-37) on a somatostatin secreting cell line. FEBS letters. vol 279. issue 2. 1991-04-17. PMID:1672112. |
our findings support a model of physiologic regulation of insulin secretion whereby glp-i(7-37) released from the intestine in response to oral nutrients potently stimulates insulin secretion via an endocrine mechanism that in turn may be dampened by a feed-back suppression by the release of somatostatin. |
1991-04-17 |
2023-08-11 |
Not clear |
H C Fehmann, J F Habene. Functional receptors for the insulinotropic hormone glucagon-like peptide-I(7-37) on a somatostatin secreting cell line. FEBS letters. vol 279. issue 2. 1991-04-17. PMID:1672112. |
in addition, suppression of the secretion of glucagon, a hormone whose actions are counter-regulatory to those of insulin, may occur by paracrine mechanisms involving glp-i(7-37)-mediated stimulation of both insulin and somatostatin secretion. |
1991-04-17 |
2023-08-11 |
Not clear |
I A Goecke, S Bonilla, E T Marusic, M Alv. Enhanced insulin sensitivity in extrarenal potassium handling in uremic rats. Kidney international. vol 39. issue 1. 1991-04-17. PMID:1672173. |
further, suppression of endogenous insulin secretion with somatostatin caused a much higher increase in plasma potassium (k) of uremic rats (1.09 +/- 0.15 meq/liter in crf vs. 0.28 +/- 0.03 meq/liter in control). |
1991-04-17 |
2023-08-11 |
rat |
C J Goodner, D J Koerker, J I Stagner, E Samol. In vitro pancreatic hormonal pulses are less regular and more frequent than in vivo. The American journal of physiology. vol 260. issue 3 Pt 1. 1991-04-12. PMID:1672242. |
insulin, glucagon, and somatostatin displayed high-amplitude secretory pulses, and the average pulse interval did not differ among the three islet hormones. |
1991-04-12 |
2023-08-11 |
monkey |
C J Goodner, D J Koerker, J I Stagner, E Samol. In vitro pancreatic hormonal pulses are less regular and more frequent than in vivo. The American journal of physiology. vol 260. issue 3 Pt 1. 1991-04-12. PMID:1672242. |
the relative amplitude averaged 142 +/- 10, 110 +/- 18, and 81 +/- 11% of the mean hormone concentrations for insulin, somatostatin, and glucagon, respectively. |
1991-04-12 |
2023-08-11 |
monkey |
O A Smirnov, B S Serezhin, I I Lomakin. [A poorly differentiated apudoma of the gallbladder]. Arkhiv patologii. vol 52. issue 8. 1991-03-11. PMID:1704208. |
numerous acth-reactive cells and single serotonin-reactive cells were revealed in the tumour parenchyma by means of immunohistochemical pap-method using antibodies against acth, serotonin, calcitonin, somatostatin, insulin, glucagon, p-substance. |
1991-03-11 |
2023-08-11 |
Not clear |
D W O'Brien, G D Molnar, T D Petersen, R V Rajott. The effect of somatostatin on insulin and glucose levels during insulin infusion in anesthetized dogs. Pancreas. vol 5. issue 6. 1991-03-11. PMID:1980734. |
the effect of somatostatin on insulin and glucose levels during insulin infusion in anesthetized dogs. |
1991-03-11 |
2023-08-11 |
Not clear |