| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Nilsson, B Winblad, L Bergströ. Diminution of preprosomatostatin-mRNA in cerebral cortex of the aged rat. Neurochemistry international. vol 27. issue 6. 1996-03-08. PMID:8574177. |
somatostatin gene expression was analysed in several regions of the cerebral cortex and hippocampus in 3, 7 and 21 month-old sprague-dawley rats using quantitative in situ hybridization with a 48mer oligodeoxynucleotide antisense probe. |
1996-03-08 |
2023-08-12 |
rat |
| G Muñoz-Acedo, R M Izquierdo-Claros, J A Sánchez-Alonso, N del Hoyo, M A Pérez-Albarsanz, E Arill. Effect of somatostatin on the mass accumulation of inositol-1,4,5-trisphosphate in rat hypothalamus, striatum, frontoparietal cortex and hippocampus. Neuroscience letters. vol 197. issue 1. 1996-02-12. PMID:8545051. |
effect of somatostatin on the mass accumulation of inositol-1,4,5-trisphosphate in rat hypothalamus, striatum, frontoparietal cortex and hippocampus. |
1996-02-12 |
2023-08-12 |
rat |
| C H Lammers, P Schweitzer, P Facchinetti, J M Arrang, S G Madamba, G R Siggins, D Piomell. Arachidonate 5-lipoxygenase and its activating protein: prominent hippocampal expression and role in somatostatin signaling. Journal of neurochemistry. vol 66. issue 1. 1996-01-24. PMID:8522947. |
arachidonate 5-lipoxygenase and its activating protein: prominent hippocampal expression and role in somatostatin signaling. |
1996-01-24 |
2023-08-12 |
rat |
| G Fontana, R De Bernardi, F Ferro, A Gemignani, M Raiter. Characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons. Journal of neurochemistry. vol 66. issue 1. 1996-01-24. PMID:8522949. |
characterization of the glutamate receptors mediating release of somatostatin from cultured hippocampal neurons. |
1996-01-24 |
2023-08-12 |
rat |
| H Ishibashi, N Akaik. Somatostatin modulates high-voltage-activated Ca2+ channels in freshly dissociated rat hippocampal neurons. Journal of neurophysiology. vol 74. issue 3. 1996-01-18. PMID:7500129. |
somatostatin modulates high-voltage-activated ca2+ channels in freshly dissociated rat hippocampal neurons. |
1996-01-18 |
2023-08-12 |
rat |
| J Carnahan, H Naw. Regulation of neuropeptide expression in the brain by neurotrophins. Potential role in vivo. Molecular neurobiology. vol 10. issue 2-3. 1995-11-29. PMID:7576304. |
neurotrophins administered into neonatal brain exhibited slightly different potencies for increasing these neuropeptides: the most marked increase in neuropeptide y levels was obtained in the neocortex by nt-5, whereas in the striatum and hippocampus by bdnf, although all three neurotrophins increased somatostatin similarly in all the brain regions examined. |
1995-11-29 |
2023-08-12 |
rat |
| N Matsuoka, M Yamazaki, I Yamaguch. Changes in brain somatostatin in memory-deficient rats: comparison with cholinergic markers. Neuroscience. vol 66. issue 3. 1995-09-21. PMID:7644025. |
neurochemistry measurements showed that lesions of the nucleus basalis magnocellularis produced a selective reduction both in the cortical cholinergic marker choline acetyltransferase and in striatal somatostatin level, whereas lesioning of the fimbria-fornix caused a marked loss of choline acetyltransferase in the hippocampus and posterior cortex, and a significant reduction in hippocampal somatostatin. |
1995-09-21 |
2023-08-12 |
rat |
| J Pérez, A Vezzani, G Civenni, P Tutka, M Rizzi, E Schüpbach, D Hoye. Functional effects of D-Phe-c[Cys-Tyr-D-Trp-Lys-Val-Cys]-Trp-NH2 and differential changes in somatostatin receptor messenger RNAs, binding sites and somatostatin release in kainic acid-treated rats. Neuroscience. vol 65. issue 4. 1995-08-22. PMID:7617164. |
in situ hybridization histochemistry for somatostatin receptors-1, -2, -3 and -4 section and receptor autoradiography using [125i]cgp 23996, [125i]somatostatin-28, [125i]seglitide and [125i]tyr3 octreotide were carried out to determine the expression of somatostatin receptor messenger rnas and binding sites in the hippocampus and cerebral cortex of rats 21 days following generalized limbic seizures induced by subcutaneous injection of 12mg/kg kainic acid. |
1995-08-22 |
2023-08-12 |
rat |
| J Pérez, A Vezzani, G Civenni, P Tutka, M Rizzi, E Schüpbach, D Hoye. Functional effects of D-Phe-c[Cys-Tyr-D-Trp-Lys-Val-Cys]-Trp-NH2 and differential changes in somatostatin receptor messenger RNAs, binding sites and somatostatin release in kainic acid-treated rats. Neuroscience. vol 65. issue 4. 1995-08-22. PMID:7617164. |
a 18 and 35% decrease in the spontaneous and 50 mm kcl-induced somatostatin release from hippocampal slices was found two days after kainate, a likely reflection of neuronal cell loss. |
1995-08-22 |
2023-08-12 |
rat |
| J C Dávila, M Megías, M J Andreu, M A Real, S Guirad. NADPH diaphorase-positive neurons in the lizard hippocampus: a distinct subpopulation of GABAergic interneurons. Hippocampus. vol 5. issue 1. 1995-07-25. PMID:7787947. |
co-localization with gaba was 100%, and nadph diaphorase-positive neurons in the lizard hippocampus did not contain parvalbumin or somatostatin. |
1995-07-25 |
2023-08-12 |
mouse |
| S López-Sañudo, L Puebla, L G Guijarro, J C Prieto, E Arill. Alpha-2 adrenoceptors modulate the somatostatinergic system and G protein levels in the rat hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 12. issue 1. 1995-07-05. PMID:7766286. |
somatostatin caused a significantly lower inhibition in ac activity in hippocampal membranes of clonidine-treated rats, whereas yohimbine led to an opposite effect. |
1995-07-05 |
2023-08-12 |
rat |
| M Ohno, M Kikusui, A Yoshimatsu, T Yamamoto, S Watanab. Somatostatin alleviates impairment of working memory induced by hippocampal muscarinic M1 receptor blockade in rats. European journal of pharmacology. vol 271. issue 2-3. 1995-05-09. PMID:7705459. |
somatostatin alleviates impairment of working memory induced by hippocampal muscarinic m1 receptor blockade in rats. |
1995-05-09 |
2023-08-12 |
rat |
| M Ohno, M Kikusui, A Yoshimatsu, T Yamamoto, S Watanab. Somatostatin alleviates impairment of working memory induced by hippocampal muscarinic M1 receptor blockade in rats. European journal of pharmacology. vol 271. issue 2-3. 1995-05-09. PMID:7705459. |
the effects of somatostatin on the impairment of working memory induced in rats by blockade of hippocampal muscarinic m1 or nmda receptors were examined, using a three-panel runway task. |
1995-05-09 |
2023-08-12 |
rat |
| M Ohno, M Kikusui, A Yoshimatsu, T Yamamoto, S Watanab. Somatostatin alleviates impairment of working memory induced by hippocampal muscarinic M1 receptor blockade in rats. European journal of pharmacology. vol 271. issue 2-3. 1995-05-09. PMID:7705459. |
these results suggest that somatostatin ameliorates the impairment of working memory resulting from hippocampal muscarinic m1 receptor blockade, possibly through activation of cholinergic functions. |
1995-05-09 |
2023-08-12 |
rat |
| R M Señarís, P P Humphrey, P C Emso. Distribution of somatostatin receptors 1, 2 and 3 mRNA in rat brain and pituitary. The European journal of neuroscience. vol 6. issue 12. 1995-05-05. PMID:7704298. |
somatostatin receptor 1 mrna was particularly concentrated in the cerebral and piriform cortex, magnocellular preoptic nucleus, hypothalamus, amygdala, hippocampus, and several nuclei of the brainstem. |
1995-05-05 |
2023-08-12 |
rat |
| R M Señarís, P P Humphrey, P C Emso. Distribution of somatostatin receptors 1, 2 and 3 mRNA in rat brain and pituitary. The European journal of neuroscience. vol 6. issue 12. 1995-05-05. PMID:7704298. |
somatostatin receptor 3 mrna was very abundant in the cerebellum and pituitary (in contrast to somatostatin receptor 1), but it was also found in hippocampus, amygdala, hypothalamus and in motor nuclei of the brainstem. |
1995-05-05 |
2023-08-12 |
rat |
| H Hörtnag. AF64A-induced brain damage and its relation to dementia. Journal of neural transmission. Supplementum. vol 44. 1995-04-27. PMID:7897396. |
the af64a-induced withdrawal of cholinergic function in the rat hippocampus was associated with reversible functional changes in other neurotransmitters, including noradrenaline, serotonin, somatostatin and glutamate, thereby mimicking changes in alzheimer's disease. |
1995-04-27 |
2023-08-12 |
rat |
| K Barnes, S Doherty, A J Turne. Endopeptidase-24.11 is the integral membrane peptidase initiating degradation of somatostatin in the hippocampus. Journal of neurochemistry. vol 64. issue 4. 1995-04-18. PMID:7891111. |
endopeptidase-24.11 is the integral membrane peptidase initiating degradation of somatostatin in the hippocampus. |
1995-04-18 |
2023-08-12 |
Not clear |
| I A Alonso, J C Prieto, E Arill. Effect of acute and chronic diisopropylfluorophosphate and atropine administration on somatostatin binding in the rat frontoparietal cortex and hippocampus. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870867. |
effect of acute and chronic diisopropylfluorophosphate and atropine administration on somatostatin binding in the rat frontoparietal cortex and hippocampus. |
1995-03-29 |
2023-08-12 |
rat |
| S Shibata, T Tanaka, S Watanab. Facilitatory effects of somatostatin on reduced uptake of 2-deoxyglucose in cerebral cortical and hippocampal slices from aged rats. European journal of pharmacology. vol 269. issue 2. 1995-03-10. PMID:7851504. |
facilitatory effects of somatostatin on reduced uptake of 2-deoxyglucose in cerebral cortical and hippocampal slices from aged rats. |
1995-03-10 |
2023-08-12 |
rat |