| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Dournaud, P Cervera-Pierot, E Hirsch, F Javoy-Agid, C Kordon, Y Agid, J Epelbau. Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. Neuroscience. vol 61. issue 4. 1995-03-02. PMID:7838375. |
somatostatin messenger rna-containing neurons in alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. |
1995-03-02 |
2023-08-12 |
human |
| P Dournaud, P Cervera-Pierot, E Hirsch, F Javoy-Agid, C Kordon, Y Agid, J Epelbau. Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. Neuroscience. vol 61. issue 4. 1995-03-02. PMID:7838375. |
somatostatin messenger rna-containing neurons displayed a similar regional and subregional distribution in control subjects and patients with alzheimer's disease, being more abundant in the frontal cortex, followed by the hippocampus and the parahippocampal cortex. |
1995-03-02 |
2023-08-12 |
human |
| P Dournaud, P Cervera-Pierot, E Hirsch, F Javoy-Agid, C Kordon, Y Agid, J Epelbau. Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. Neuroscience. vol 61. issue 4. 1995-03-02. PMID:7838375. |
a significantly lower level of expression of somatostatin messenger rna per somatostatinergic cell was observed in the hippocampus of alzheimer's disease patients (-47%, p < 0.05), but not in frontal cortex gray (-17%) and white (-36%) matter and parahippocampal cortex gray (-42%) and white (-29%) matter. |
1995-03-02 |
2023-08-12 |
human |
| M Mori, H Bito, C Sakanaka, Z Honda, K Kume, T Izumi, T Shimiz. Activation of mitogen-activated protein kinase and arachidonate release via two G protein-coupled receptors expressed in the rat hippocampus. Annals of the New York Academy of Sciences. vol 744. 1995-02-14. PMID:7825832. |
platelet-activating factor and somatostatin receptors, two g protein-coupled receptors expressed in the rat hippocampus, were analyzed for the downstream signaling pathways in chinese hamster ovary cells stably expressing each receptor. |
1995-02-14 |
2023-08-12 |
rat |
| S López-Sañudo, E Arill. Changes in alpha 1-adrenergic neurotransmission alter the number of somatostatin receptors in the rat hippocampus. Neuroscience letters. vol 177. issue 1-2. 1995-02-10. PMID:7529902. |
changes in alpha 1-adrenergic neurotransmission alter the number of somatostatin receptors in the rat hippocampus. |
1995-02-10 |
2023-08-12 |
rat |
| C Sakanaka, I Ferby, I Waga, H Bito, T Shimiz. On the mechanism of cytosolic phospholipase A2 activation in CHO cells carrying somatostatin receptor: wortmannin-sensitive pathway to activate mitogen-activated protein kinase. Biochemical and biophysical research communications. vol 205. issue 1. 1995-01-17. PMID:7999020. |
we examined the mechanism of arachidonate release induced by somatostatin-14 (ss14) in cho-k1 cells overexpressing rat hippocampal somatostatin receptor sstr4. |
1995-01-17 |
2023-08-12 |
rat |
| N Tønder, J Kragh, B R Finsen, T G Bolwig, J Zimme. Kindling induces transient changes in neuronal expression of somatostatin, neuropeptide Y, and calbindin in adult rat hippocampus and fascia dentata. Epilepsia. vol 35. issue 6. 1995-01-10. PMID:7988524. |
kindling induces transient changes in neuronal expression of somatostatin, neuropeptide y, and calbindin in adult rat hippocampus and fascia dentata. |
1995-01-10 |
2023-08-12 |
rat |
| S D Croll, S J Wiegand, K D Anderson, R M Lindsay, H Naw. Regulation of neuropeptides in adult rat forebrain by the neurotrophins BDNF and NGF. The European journal of neuroscience. vol 6. issue 8. 1994-12-30. PMID:7981876. |
bdnf produced elevations of peptide and mrna for neuropeptide y and cholecystokinin in hippocampus and cortex, and somatostatin in cortex. |
1994-12-30 |
2023-08-12 |
rat |
| J T Erichsen, A Ciocchetti, G Fontanesi, P Bagnol. Neuroactive substances in the developing dorsomedial telencephalon of the pigeon (Columba livia): differential distribution and time course of maturation. The Journal of comparative neurology. vol 345. issue 4. 1994-12-28. PMID:7525663. |
the distribution of two transmitter-related enzymes, choline acetyltransferase (chat) and tyrosine hydroxylase (th), the neurotransmitter gaba, and four neuropeptides (substance p, enkephalin, neuropeptide y, and somatostatin) was studied by immunohistochemistry in the developing hippocampal complex. |
1994-12-28 |
2023-08-12 |
pigeon |
| P S Buckmaster, D D Kunkel, R J Robbins, P A Schwartzkroi. Somatostatin-immunoreactivity in the hippocampus of mouse, rat, guinea pig, and rabbit. Hippocampus. vol 4. issue 2. 1994-12-20. PMID:7951691. |
the distributions of somatostatin-immunoreactive somata and fiber plexuses were determined, and the concentration of somatostatin along the septotemporal axis of the hippocampus was measured using a radioimmunoassay. |
1994-12-20 |
2023-08-12 |
mouse |
| D R Hampson, E Theriault, X P Huang, P Kristensen, D S Pickering, J E Franck, E R Mulvihil. Characterization of two alternatively spliced forms of a metabotropic glutamate receptor in the central nervous system of the rat. Neuroscience. vol 60. issue 2. 1994-09-23. PMID:8072687. |
the presence of mglur1 alpha in cells of the hippocampus that are associated with the release of somatostatin, suggest that this receptor could play a role in regulating hippocampal excitability in both normal and epileptic tissues. |
1994-09-23 |
2023-08-12 |
rat |
| J Kragh, N Tønder, B R Finsen, J Zimmer, T G Bolwi. Repeated electroconvulsive shocks cause transient changes in rat hippocampal somatostatin and neuropeptide Y immunoreactivity and mRNA in situ hybridization signals. Experimental brain research. vol 98. issue 2. 1994-09-08. PMID:7914171. |
repeated electroconvulsive shocks cause transient changes in rat hippocampal somatostatin and neuropeptide y immunoreactivity and mrna in situ hybridization signals. |
1994-09-08 |
2023-08-12 |
rat |
| O A Shandra, L S Hodlevskyĭ, R S Vastíanov, A V Panenk. [Effect of intracerebral injections of somatostatin and neurotensin on motor functions in seizure]. Fiziologicheskii zhurnal. vol 39. issue 5-6. 1994-08-30. PMID:7913897. |
experiments were performed on male wistar rats with the aim to study effects exerted by microinjections of somatostatin and neurotensin into lateral ventricle, amygdala, hippocampus and substantia nigra pars reticulata in case of epileptic activity. |
1994-08-30 |
2023-08-12 |
rat |
| L Puebla, E Arill. Somatostatin receptor-GTP binding regulatory protein-adenylyl cyclase system in hippocampal membranes of strychnine-treated rats. Brain research. vol 644. issue 1. 1994-08-17. PMID:7913402. |
somatostatin receptor-gtp binding regulatory protein-adenylyl cyclase system in hippocampal membranes of strychnine-treated rats. |
1994-08-17 |
2023-08-12 |
rat |
| H Bito, M Mori, C Sakanaka, T Takano, Z Honda, Y Gotoh, E Nishida, T Shimiz. Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade. The Journal of biological chemistry. vol 269. issue 17. 1994-06-06. PMID:8175684. |
functional coupling of sstr4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade. |
1994-06-06 |
2023-08-12 |
rat |
| H Bito, M Mori, C Sakanaka, T Takano, Z Honda, Y Gotoh, E Nishida, T Shimiz. Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade. The Journal of biological chemistry. vol 269. issue 17. 1994-06-06. PMID:8175684. |
somatostatin has a modulatory role in regulating the membrane conductance in hippocampal neurons. |
1994-06-06 |
2023-08-12 |
rat |
| H Bito, M Mori, C Sakanaka, T Takano, Z Honda, Y Gotoh, E Nishida, T Shimiz. Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade. The Journal of biological chemistry. vol 269. issue 17. 1994-06-06. PMID:8175684. |
to examine the signal transducing molecules involved in this process, we isolated the cdna encoding the dominant rat hippocampal somatostatin receptor, sstr4. |
1994-06-06 |
2023-08-12 |
rat |
| H Bito, M Mori, C Sakanaka, T Takano, Z Honda, Y Gotoh, E Nishida, T Shimiz. Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade. The Journal of biological chemistry. vol 269. issue 17. 1994-06-06. PMID:8175684. |
these data indicate that the hippocampal functions of somatostatin might be mediated through diverse but selective second messenger systems activated via sstr4 and reveal an unsuspected coupling of a neuronal sstr subtype to a mitogenic signaling pathway. |
1994-06-06 |
2023-08-12 |
rat |
| A Takazawa, W C Abraham, Y Sekin. Cysteamine potentiates entorhinal activation of dentate gyrus granule cells in rats. Brain research bulletin. vol 33. issue 4. 1994-04-13. PMID:7907266. |
in the hippocampal slice preparation, a similar effect of the drug (1-5 mm) on dentate evoked potentials was observed, suggesting that cysteamine acts through its effects on somatostatin in the hippocampus itself. |
1994-04-13 |
2023-08-12 |
rat |
| A Takazawa, W C Abraham, Y Sekin. Cysteamine potentiates entorhinal activation of dentate gyrus granule cells in rats. Brain research bulletin. vol 33. issue 4. 1994-04-13. PMID:7907266. |
these results suggest that hippocampal somatostatin released by cysteamine potentiates the response of dentate granule cells to perforant path input, without directly affecting synaptic transmission or general cell excitability. |
1994-04-13 |
2023-08-12 |
rat |