| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Vezzani, C Schwarzer, E W Lothman, J Williamson, G Sper. Functional changes in somatostatin and neuropeptide Y containing neurons in the rat hippocampus in chronic models of limbic seizures. Epilepsy research. vol 26. issue 1. 1997-04-14. PMID:8985706. |
using immunocytochemistry and in situ hybridization analysis of mrna, we investigated the changes in the expression of somatostatin and neuropeptide y (npy) in the rat hippocampal principal neurons in kindling or after electrically induced status epilepticus (se), two models of limbic epilepsy associated with different chronic sequelae of seizures and seizure-related neuropathology. |
1997-04-14 |
2023-08-12 |
rat |
| A Vezzani, C Schwarzer, E W Lothman, J Williamson, G Sper. Functional changes in somatostatin and neuropeptide Y containing neurons in the rat hippocampus in chronic models of limbic seizures. Epilepsy research. vol 26. issue 1. 1997-04-14. PMID:8985706. |
in the hippocampus proper of kindled rats, somatostatin and npy ir were respectively enhanced in the stratum lacunosum moleculare, the subiculum and in the alveus while no significant changes were observed after se. |
1997-04-14 |
2023-08-12 |
rat |
| C Piwko, V S Thoss, R Samanin, D Hoyer, A Vezzan. Status of somatostatin receptor messenger RNAs and binding sites in rat brain during kindling epileptogenesis. Neuroscience. vol 75. issue 3. 1997-03-19. PMID:8951879. |
in situ hybridization histochemistry with somatostatin sst1-sst5 receptor messenger rna-selective oligoprobes and quantitative receptor autoradiographic binding studies using [125i]tyr3-octreotide, [leu2,d-trp22,125i-tyr25]somatostatin-28 and [125i]cgp 23996 ([125i]c[asn-lys-asn-phe-phe-trp-lys-thr-tyr-thr-ser]) were performed to determine the level of expression of somatostatin receptor messenger rna and receptor binding sites in the hippocampal formation, limbic system and cerebral cortex of adult rats electrically kindled in the dorsal hippocampus. |
1997-03-19 |
2023-08-12 |
rat |
| D P Woldbye, T M Madsen, P J Larsen, J D Mikkelsen, T G Bolwi. Neuropeptide Y inhibits hippocampal seizures and wet dog shakes. Brain research. vol 737. issue 1-2. 1997-02-20. PMID:8930362. |
the effects of intracerebroventricular neuropeptide y (npy) or somatostatin were studied upon hippocampal eeg seizures elicited by electrical stimulation of the rat dentate gyrus or subiculum. |
1997-02-20 |
2023-08-12 |
rat |
| T Halonen, J Nissinen, J A Jansen, A Pitkäne. Tiagabine prevents seizures, neuronal damage and memory impairment in experimental status epilepticus. European journal of pharmacology. vol 299. issue 1-3. 1997-01-23. PMID:8901009. |
in the same rats, tiagabine treatment reduced the loss of pyramidal cells in the ca3c and ca1 fields of the hippocampus (p < 0.05) but not the loss of somatostatin immunoreactive neurons in the hilus. |
1997-01-23 |
2023-08-12 |
rat |
| M Yamazaki, N Matsuoka, N Maeda, Y Ohkubo, I Yamaguch. FK960 N-(4-acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate ameliorates the memory deficits in rats through a novel mechanism of action. The Journal of pharmacology and experimental therapeutics. vol 279. issue 3. 1997-01-23. PMID:8968337. |
dose-dependently increased both serotonin and 5-hydroxyindoleacetic acid levels in the brain areas examined and significantly increased hippocampal somatostatin contents at the smaller doses. |
1997-01-23 |
2023-08-12 |
rat |
| K Kuki, K Maeda, S Takauchi, T Kakigi, S Maeda, C Tanak. Neurochemical and pathological alterations following infusion of leupeptin, a protease inhibitor, into the rat brain. Dementia (Basel, Switzerland). vol 7. issue 5. 1997-01-10. PMID:8872412. |
we found a significant reduction of regional choline acetyltransferase activities in the hippocampus, and of somatostatin concentrations in the hypothalamus and entorhinal cortex. |
1997-01-10 |
2023-08-12 |
rat |
| C Schwarzer, G Sperk, R Samanin, M Rizzi, M Gariboldi, A Vezzan. Neuropeptides-immunoreactivity and their mRNA expression in kindling: functional implications for limbic epileptogenesis. Brain research. Brain research reviews. vol 22. issue 1. 1996-12-27. PMID:8871784. |
this will be done by presenting a study in which we investigated the changes in the expression of somatostatin, neuropeptide y (npy), neurokinin b (nkb) and cholecystokinin-octapeptide (cck) in the rat hippocampal principal neurons during and after kindling of the hippocampus using immunocytochemistry and in situ hybridization analysis of mrna. |
1996-12-27 |
2023-08-12 |
rat |
| C Schwarzer, G Sperk, R Samanin, M Rizzi, M Gariboldi, A Vezzan. Neuropeptides-immunoreactivity and their mRNA expression in kindling: functional implications for limbic epileptogenesis. Brain research. Brain research reviews. vol 22. issue 1. 1996-12-27. PMID:8871784. |
in the hippocampus proper, somatostatin and npy-ir were enhanced in the stratum lacunosum molecular while cck-ir fibres and its mrna were particularly expressed in the pyramidal cell layer. |
1996-12-27 |
2023-08-12 |
rat |
| C Schwarzer, G Sperk, C Rauca, W Pohl. Neuropeptide Y and somatostatin immunoreactivity in the rat hippocampus after moderate hypoxia. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 1. 1996-12-11. PMID:8832590. |
neuropeptide y and somatostatin immunoreactivity in the rat hippocampus after moderate hypoxia. |
1996-12-11 |
2023-08-12 |
rat |
| C Schwarzer, G Sperk, C Rauca, W Pohl. Neuropeptide Y and somatostatin immunoreactivity in the rat hippocampus after moderate hypoxia. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 1. 1996-12-11. PMID:8832590. |
we now investigated neuropeptide y and somatostatin immunoreactivities seven days after moderate hypoxia (9% o2 in n2 for two times 8 h) in the hippocampus of the rat. |
1996-12-11 |
2023-08-12 |
rat |
| C Schwarzer, G Sperk, C Rauca, W Pohl. Neuropeptide Y and somatostatin immunoreactivity in the rat hippocampus after moderate hypoxia. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 1. 1996-12-11. PMID:8832590. |
a slight reduction of somatostatin immunoreactive cells was observed in the hilus of the dorsal and ventral hippocampus. |
1996-12-11 |
2023-08-12 |
rat |
| A Nakata, H Saito, N Nishiyam. Facilitatory role of somatostatin via muscarinic cholinergic system in the generation of long-term potentiation in the rat dentate gyrus in vivo. Brain research. vol 723. issue 1-2. 1996-12-03. PMID:8813390. |
we next tested whether the ltp-augmenting effect of somatostain is mediated by cholinergic activation, because somatostatin was demonstrated to promote acetylcholine release in rat hippocampal slice. |
1996-12-03 |
2023-08-12 |
rat |
| L Seress, C Lerant. Distribution of substance P-immunoreactive neurons and fibers in the monkey hippocampal formation. Neuroscience. vol 71. issue 3. 1996-12-03. PMID:8867037. |
hippocampal neurons, which were immunoreactive for substance p, also contained the neuropeptide somatostatin. |
1996-12-03 |
2023-08-12 |
monkey |
| P Dournaud, F Jazat-Poindessous, A Slama, Y Lamour, J Epelbau. Correlations between water maze performance and cortical somatostatin mRNA and high-affinity binding sites during ageing in rats. The European journal of neuroscience. vol 8. issue 3. 1996-12-03. PMID:8963438. |
the number of somatostatin mrna-containing cells was not modified with age or memory performance in cortical, hippocampal and hypothalamic regions, but somatostatin mrna densities were significantly decreased with age and with memory performance in the frontal and parietal cortex. |
1996-12-03 |
2023-08-12 |
rat |
| L Puebla, E Rodríguez-Martín, E Arill. Hippocampal somatostatin receptors and modulation of adenylyl cyclase activity in histamine-treated rats. Brain research. Molecular brain research. vol 35. issue 1-2. 1996-10-11. PMID:8717342. |
hippocampal somatostatin receptors and modulation of adenylyl cyclase activity in histamine-treated rats. |
1996-10-11 |
2023-08-12 |
rat |
| M Schindler, K A Harrington, P P Humphrey, P C Emso. Cellular localisation and co-expression of somatostatin receptor messenger RNAs in the human brain. Brain research. Molecular brain research. vol 34. issue 2. 1996-10-11. PMID:8750836. |
in situ hybridisation studies using co-expression techniques with probes for sst1, sst3 and sst4 receptor mrna on paraffin sections revealed the presence of neurones expressing more than one somatostatin receptor mrna type in both the hippocampus and pyramidal cells of layer v of the frontal cortex. |
1996-10-11 |
2023-08-12 |
human |
| L Puebla, E Arill. Glycine increases the number of somatostatin receptors and somatostatin-mediated inhibition of the adenylate cyclase system in the rat hippocampus. Journal of neuroscience research. vol 43. issue 3. 1996-10-08. PMID:8714523. |
glycine increases the number of somatostatin receptors and somatostatin-mediated inhibition of the adenylate cyclase system in the rat hippocampus. |
1996-10-08 |
2023-08-12 |
rat |
| L de Lecea, J R Criado, O Prospero-Garcia, K M Gautvik, P Schweitzer, P E Danielson, C L Dunlop, G R Siggins, S J Henriksen, J G Sutcliff. A cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature. vol 381. issue 6579. 1996-06-19. PMID:8622767. |
administration of cortistatin depresses neuronal electrical activity but, unlike somatostatin, induces low-frequency waves in the cerebral cortex and antagonizes the effects of acetylcholine on hippocampal and cortical measures of excitability. |
1996-06-19 |
2023-08-12 |
Not clear |
| R Bering, N H Diemer, A Draguhn, F F Johanse. Co-localization of somatostatin mRNA and parvalbumin in the dorsal rat hippocampus after cerebral ischemia. Hippocampus. vol 5. issue 4. 1996-03-22. PMID:8589797. |
co-localization of somatostatin mrna and parvalbumin in the dorsal rat hippocampus after cerebral ischemia. |
1996-03-22 |
2023-08-12 |
rat |