| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Sutcliffe, L de Lece. Novel neurotransmitters for sleep and energy homeostasis. Results and problems in cell differentiation. vol 26. 1999-10-06. PMID:10453467. |
one postnatal-onset mrna, restricted to sparse gabaergic interneurons of the cerebral cortex and hippocampus, encodes preprocortistatin, the precursor of a 14-residue peptide that shares 11 amino acids with somatostatin. |
1999-10-06 |
2023-08-12 |
Not clear |
| E Van Uden, I Veinbergs, M Mallory, R Orlando, E Maslia. A novel role for receptor-associated protein in somatostatin modulation: implications for Alzheimer's disease. Neuroscience. vol 88. issue 3. 1999-08-02. PMID:10363810. |
in wild-type mice, the receptor-associated protein was found to be highly co-expressed with somatostatin in hippocampal and neocortical inhibitory neurons. |
1999-08-02 |
2023-08-12 |
mouse |
| J R Criado, H Li, X Jiang, M Spina, S Huitrón-Reséndiz, G Liapakis, M Calbet, S Siehler, S J Henriksen, G Koob, D Hoyer, J G Sutcliffe, M Goodman, L de Lece. Structural and compositional determinants of cortistatin activity. Journal of neuroscience research. vol 56. issue 6. 1999-07-29. PMID:10374816. |
cortistatin-14 (cst-14) is a putative novel neuropeptide that shares 11 of its 14 residues with somatostatin-14 (srif-14), yet its effects on sleep physiology, locomotor behavior and hippocampal function are different from those of somatostatin. |
1999-07-29 |
2023-08-12 |
Not clear |
| J R Criado, H Li, X Jiang, M Spina, S Huitrón-Reséndiz, G Liapakis, M Calbet, S Siehler, S J Henriksen, G Koob, D Hoyer, J G Sutcliffe, M Goodman, L de Lece. Structural and compositional determinants of cortistatin activity. Journal of neuroscience research. vol 56. issue 6. 1999-07-29. PMID:10374816. |
biological assays were carried out to determine their binding affinities to five somatostatin receptors (sstl-5) and their ability to produce changes in locomotor activity and to modulate hippocampal physiology and sleep. |
1999-07-29 |
2023-08-12 |
Not clear |
| M Pascual, L Acsády, N Rocamora, T F Freund, E Sorian. Expression of neurotrophins in hippocampal interneurons immunoreactive for the neuropeptides somatostatin, neuropeptide-Y, vasoactive intestinal polypeptide and cholecystokinin. Neuroscience. vol 89. issue 4. 1999-07-22. PMID:10362297. |
expression of neurotrophins in hippocampal interneurons immunoreactive for the neuropeptides somatostatin, neuropeptide-y, vasoactive intestinal polypeptide and cholecystokinin. |
1999-07-22 |
2023-08-12 |
Not clear |
| M Pascual, L Acsády, N Rocamora, T F Freund, E Sorian. Expression of neurotrophins in hippocampal interneurons immunoreactive for the neuropeptides somatostatin, neuropeptide-Y, vasoactive intestinal polypeptide and cholecystokinin. Neuroscience. vol 89. issue 4. 1999-07-22. PMID:10362297. |
using a double detection method, which combines in situ hybridization for the detection of neurotrophin messenger rna with immunocytochemistry against the neuropeptides somatostatin, neuropeptide y, vasoactive intestinal polypeptide and cholecystokinin, we have analysed the expression of the neurotrophins, nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3, in distinct populations of neuropeptide-immunoreactive hippocampal interneurons. |
1999-07-22 |
2023-08-12 |
Not clear |
| M Pascual, L Acsády, N Rocamora, T F Freund, E Sorian. Expression of neurotrophins in hippocampal interneurons immunoreactive for the neuropeptides somatostatin, neuropeptide-Y, vasoactive intestinal polypeptide and cholecystokinin. Neuroscience. vol 89. issue 4. 1999-07-22. PMID:10362297. |
our data showed that the four populations of hippocampal interneurons studied (somatostatin, neuropeptide-y, vasoactive intestinal polypeptide and cholescystokinin) received gabaergic afferents from the septum. |
1999-07-22 |
2023-08-12 |
Not clear |
| M Händel, S Schulz, A Stanarius, M Schreff, M Erdtmann-Vourliotis, H Schmidt, G Wolf, V Höll. Selective targeting of somatostatin receptor 3 to neuronal cilia. Neuroscience. vol 89. issue 3. 1999-07-07. PMID:10199624. |
using specific anti-peptide antisera, we observed somatostatin receptor 3-like immunoreactivity in many brain regions, including the cerebral cortex, hippocampus, hypothalamus, amygdala and cerebellum. |
1999-07-07 |
2023-08-12 |
Not clear |
| S B Qi, X Y Wang, Y L Zhou, L Zhang, H Z Ruan, J Wang, X C L. [Effects of new constituents L-6a and L-10 from leaves of Luffa cylinderica on learning, memory, and hippocampal somatostatin in rats]. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 18. issue 6. 1999-07-07. PMID:10322912. |
[effects of new constituents l-6a and l-10 from leaves of luffa cylinderica on learning, memory, and hippocampal somatostatin in rats]. |
1999-07-07 |
2023-08-12 |
rat |
| S B Qi, X Y Wang, Y L Zhou, L Zhang, H Z Ruan, J Wang, X C L. [Effects of new constituents L-6a and L-10 from leaves of Luffa cylinderica on learning, memory, and hippocampal somatostatin in rats]. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 18. issue 6. 1999-07-07. PMID:10322912. |
to study the effects of two constituents l-6a and l-10 from the leaves of luffa cylinderica roem on learning, memory, and hippocampal somatostatin in rats. |
1999-07-07 |
2023-08-12 |
rat |
| M K Tallent, G R Siggin. Somatostatin acts in CA1 and CA3 to reduce hippocampal epileptiform activity. Journal of neurophysiology. vol 81. issue 4. 1999-05-13. PMID:10200199. |
somatostatin acts in ca1 and ca3 to reduce hippocampal epileptiform activity. |
1999-05-13 |
2023-08-12 |
rat |
| X Kong, R Ren, L Li. [Effects of zinc deficiency in fodder on brain development, learning and memory in rats]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. vol 31. issue 5. 1999-02-26. PMID:9812610. |
results showed that 1. brain weight, hippocampal weight, and serum and hippocampal zinc concentrations were significantly lower in zd group than those in controls; 2. proportion of induced long-term potentiation (ltp) was zero in zd group and proportion of active avoidance response decreased profoundly in zd group, significantly lower than that in normal controls whose ltp proportion was 100%; 3. concentrations of excitatory and inhibitory amino acids, glutamic acid, gamma-aminobutyric acid in cerebral cortex and hippocampus and nitrous oxide in hippocampus were significantly higher in zd group than those in normal one, and content of somatostatin in hippocampus and dna in pyramidocytes were significantly lower in zd group than those in normal one; and 4. number of synaptic vesicles in pyramidocytes of hippocampus decreased obviously in zd group. |
1999-02-26 |
2023-08-12 |
rat |
| K Fuxe, A Jansson, Z Diaz-Cabiale, A Andersson, B Tinner, U B Finnman, I Misane, H Razani, F H Wang, L F Agnati, S O Ogre. Galanin modulates 5-hydroxytryptamine functions. Focus on galanin and galanin fragment/5-hydroxytryptamine1A receptor interactions in the brain. Annals of the New York Academy of Sciences. vol 863. 1999-02-16. PMID:9928178. |
moreover, following intracerebroventricular injection galanin was found to be internalized in a population of hippocampal nerve cells mainly representing gaba, somatostatin, and/or npy-immunoreactive nerve cells. |
1999-02-16 |
2023-08-12 |
rat |
| P T Schwartz, M Vallej. Differential regulation of basal and cyclic adenosine 3',5'-monophosphate-induced somatostatin gene transcription in neural cells by DNA control elements that bind homeodomain proteins. Molecular endocrinology (Baltimore, Md.). vol 12. issue 9. 1998-11-25. PMID:9731698. |
we show that in cerebrocortical and hippocampal cells, expression of the somatostatin gene is regulated by several negative and positive dna cis-regulatory elements located throughout the promoter region. |
1998-11-25 |
2023-08-12 |
rat |
| S Nag, F Tan. Cholinergic lesions of the rat brain by ibotenic acid and 192 IgG-saporin: effects on somatostatin, substance P and neuropeptide Y levels in the cerebral cortex and the hippocampus. Neuroscience letters. vol 252. issue 2. 1998-11-23. PMID:9756327. |
cholinergic lesions of the rat brain by ibotenic acid and 192 igg-saporin: effects on somatostatin, substance p and neuropeptide y levels in the cerebral cortex and the hippocampus. |
1998-11-23 |
2023-08-12 |
rat |
| K Tsunashima, M Sadamatsu, Y Takahashi, N Kato, G Sper. Trimethyltin intoxication induces marked changes in neuropeptide expression in the rat hippocampus. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661251. |
in situ hybridization and immunocytochemistry were applied to investigate changes in the expression of somatostatin, neuropeptide y, neurokinin b, cholecystokinin, dynorphin, and met-enkephalin in the rat hippocampus after administration of a single peroral dose of trimethyltin hydroxide (9 mg/kg). |
1998-09-24 |
2023-08-12 |
rat |
| N Matsuoka, M Sato. FK960, a novel potential anti-dementia drug, augments long-term potentiation in mossy fiber-CA3 pathway of guinea-pig hippocampal slices. Brain research. vol 794. issue 2. 1998-08-27. PMID:9622644. |
in hippocampal slices from animals treated with cysteamine (200 mg/kg, s.c.), which was shown to deplete the hippocampal somatostatin, fk960 (10-7 m) hardly affected the ltp. |
1998-08-27 |
2023-08-12 |
rat |
| M Schindler, S Holloway, P P Humphrey, H Waldvogel, R L Faull, W Berger, P C Emso. Localization of the somatostatin sst2(a) receptor in human cerebral cortex, hippocampus and cerebellum. Neuroreport. vol 9. issue 3. 1998-04-29. PMID:9512400. |
localization of the somatostatin sst2(a) receptor in human cerebral cortex, hippocampus and cerebellum. |
1998-04-29 |
2023-08-12 |
human |
| P Schweitzer, S G Madamba, G R Siggin. Somatostatin increases a voltage-insensitive K+ conductance in rat CA1 hippocampal neurons. Journal of neurophysiology. vol 79. issue 3. 1998-04-24. PMID:9497404. |
somatostatin increases a voltage-insensitive k+ conductance in rat ca1 hippocampal neurons. |
1998-04-24 |
2023-08-12 |
rat |
| J Mitchel. Tetanus toxin-enhanced GABA immunoreactivity in living neurons. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 46. issue 3. 1998-04-21. PMID:9487113. |
this article describes a procedure using tetanus toxin which, when applied to organotypic hippocampal cultures, considerably enhances the immunoreactivity in the dendrites and axons of the gaba- and somatostatin-containing neurons and clearly demonstrates the co-localization of gaba and somatostatin immunoreactivities in the same neuron. |
1998-04-21 |
2023-08-12 |
Not clear |