| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Léa Milan, Gilles Courtand, Laura Cardoit, Frédérique Masmejean, Grégory Barrière, Jean-René Cazalets, Maurice Garret, Sandrine S Bertran. Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1G93A Lumbar Motoneurons. PloS one. vol 10. issue 8. 2016-05-16. PMID:26305672. |
our data demonstrated for the first time that the lamina x cholinergic interneurons, the neuronal source of c-boutons, are over-abundant in high lumbar segments in sod1 mice and are subject to neurodegeneration in the sod1 animal model. |
2016-05-16 |
2023-08-13 |
mouse |
| David J Baker, Daniel J Blackburn, Marcus Keatinge, Dilraj Sokhi, Paulius Viskaitis, Paul R Heath, Laura Ferraiuolo, Janine Kirby, Pamela J Sha. Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis. Frontiers in cellular neuroscience. vol 9. 2015-11-03. PMID:26528138. |
here, we have performed microarray analysis of symptomatic and late-stage disease astrocytes isolated by laser capture microdissection (lcm) from the lumbar spinal cord of the sod1(g93a) mouse to complete the picture of astrocyte behavior throughout the disease course. |
2015-11-03 |
2023-08-13 |
mouse |
| Karen S Coughlan, Mollie R Mitchem, Marion C Hogg, Jochen H M Preh. "Preconditioning" with latrepirdine, an adenosine 5'-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1(G93A) mice. Neurobiology of aging. vol 36. issue 2. 2015-09-21. PMID:25443289. |
we noted a strong activation of ampk in lumbar spinal cords of sod1(g93a) mice. |
2015-09-21 |
2023-08-13 |
mouse |
| Karen S Coughlan, Mollie R Mitchem, Marion C Hogg, Jochen H M Preh. "Preconditioning" with latrepirdine, an adenosine 5'-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1(G93A) mice. Neurobiology of aging. vol 36. issue 2. 2015-09-21. PMID:25443289. |
treatment with latrepirdine increased ampk activity in primary mouse motor neuron cultures and in sod1(g93a) lumbar spinal cords. |
2015-09-21 |
2023-08-13 |
mouse |
| Anna Tury, Kristine Tolentino, Yimin Zo. Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Developmental neurobiology. vol 74. issue 8. 2015-05-12. PMID:24123880. |
apkc expression was increased in motor neurons of the lumbar spinal cord in sod1 (g93a) mice at both early and late stages. |
2015-05-12 |
2023-08-12 |
mouse |
| Anna Tury, Kristine Tolentino, Yimin Zo. Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Developmental neurobiology. vol 74. issue 8. 2015-05-12. PMID:24123880. |
ryk expression was also increased in the motor neurons and the white matter in the ventral lumbar spinal cord of mutant sod1 mice with a peak at early stage. |
2015-05-12 |
2023-08-12 |
mouse |
| Katharina A Quinlan, Jonathan B Lamano, Julienne Samuels, C J Heckma. Comparison of dendritic calcium transients in juvenile wild type and SOD1(G93A) mouse lumbar motoneurons. Frontiers in cellular neuroscience. vol 9. 2015-04-27. PMID:25914627. |
comparison of dendritic calcium transients in juvenile wild type and sod1(g93a) mouse lumbar motoneurons. |
2015-04-27 |
2023-08-13 |
mouse |
| Motoko Kawaguchi-Niida, Tomoko Yamamoto, Yoichiro Kato, Yuri Inose, Noriyuki Shibat. MCP-1/CCR2 signaling-mediated astrocytosis is accelerated in a transgenic mouse model of SOD1-mutated familial ALS. Acta neuropathologica communications. vol 1. 2015-03-31. PMID:24252211. |
we here demonstrate the expression state of mcp-1 and ccr2 in lumbar spinal cords of mice overexpressing a transgene for g93a mutant human superoxide dismutase 1 (sod1) (als mice) as a mouse model of als as well as the involvement of mcp-1/ccr2-mediated signaling in behavior of cultured astrocytes derived from those mice. |
2015-03-31 |
2023-08-12 |
mouse |
| Léa Milan, Grégory Barrière, Philippe De Deurwaerdère, Jean-René Cazalets, Sandrine S Bertran. Monoaminergic control of spinal locomotor networks in SOD1G93A newborn mice. Frontiers in neural circuits. vol 8. 2015-03-30. PMID:25071458. |
using a post-mortem analysis by high performance liquid chromatography (hplc), monoaminergic neuromodulators and their metabolites were quantified in the lumbar spinal cord of sod1 and wild-type (wt) mice aged one postnatal day (p1) and p10. |
2015-03-30 |
2023-08-13 |
mouse |
| Léa Milan, Grégory Barrière, Philippe De Deurwaerdère, Jean-René Cazalets, Sandrine S Bertran. Monoaminergic control of spinal locomotor networks in SOD1G93A newborn mice. Frontiers in neural circuits. vol 8. 2015-03-30. PMID:25071458. |
this analysis underscores an increased content of da in the sod1 lumbar spinal cord compared to that of wt mice but failed to reveal any modification of the other monoaminergic contents. |
2015-03-30 |
2023-08-13 |
mouse |
| Léa Milan, Grégory Barrière, Philippe De Deurwaerdère, Jean-René Cazalets, Sandrine S Bertran. Monoaminergic control of spinal locomotor networks in SOD1G93A newborn mice. Frontiers in neural circuits. vol 8. 2015-03-30. PMID:25071458. |
this study was performed in p1-p3 sod1 mice and age-matched control littermates using extracellular recordings from the lumbar ventral roots in the in vitro isolated spinal cord preparation. |
2015-03-30 |
2023-08-13 |
mouse |
| Alexandre Henriques, Stefan Kastner, Eva Chatzikonstantinou, Claudia Pitzer, Christian Plaas, Friederike Kirsch, Oliver Wafzig, Carola Krüger, Robert Spoelgen, Jose-Luis Gonzalez De Aguilar, Norbert Gretz, Armin Schneide. Gene expression changes in spinal motoneurons of the SOD1(G93A) transgenic model for ALS after treatment with G-CSF. Frontiers in cellular neuroscience. vol 8. 2015-02-05. PMID:25653590. |
to gain insight into the disease mechanisms and mode of action of g-csf, we performed gene expression profiling on isolated lumbar motoneurons from sod1(g93a) mice, the most frequently studied animal model for als, with and without g-csf treatment. |
2015-02-05 |
2023-08-13 |
mouse |
| Katie Nolan, Mollie R Mitchem, Eva M Jimenez-Mateos, David C Henshall, Caoimhín G Concannon, Jochen H M Preh. Increased expression of microRNA-29a in ALS mice: functional analysis of its inhibition. Journal of molecular neuroscience : MN. vol 53. issue 2. 2015-01-02. PMID:24696165. |
in situ hybridisation experiments revealed increased mir-29a expression in the lumbar spinal cord of sod1(g93a) transgenic mice from postnatal day 70 onward when compared to wild-type mice. |
2015-01-02 |
2023-08-13 |
mouse |
| Jessica R Maximino, Gabriela P de Oliveira, Chrystian J Alves, Gerson Chad. Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1(G93A) Amyotrophic Lateral Sclerosis mouse model. Frontiers in cellular neuroscience. vol 8. 2014-06-06. PMID:24904291. |
database for annotation, visualization and integrated discovery (david) tool identified cytoskeleton-related genes by employing the cellular component ontology (cco) in a large gene profiling of lumbar spinal cord and sciatic nerve of presymptomatic sod1(g93a) mice. |
2014-06-06 |
2023-08-13 |
mouse |
| Samantha Zinkie, Benoit J Gentil, Sandra Minotti, Heather D Durha. Expression of the protein chaperone, clusterin, in spinal cord cells constitutively and following cellular stress, and upregulation by treatment with Hsp90 inhibitor. Cell stress & chaperones. vol 18. issue 6. 2014-04-14. PMID:23595219. |
clusterin expression was not altered in cultured motor neurons expressing sod1(g93a) by gene transfer or in presymptomatic sod1(g93a) transgenic mice; however, clusterin immunolabeling was weakly increased in lumbar spinal cord of overtly symptomatic mice. |
2014-04-14 |
2023-08-12 |
mouse |
| Wentao Liu, Toru Yamashita, Fengfeng Tian, Nobutoshi Morimoto, Yoshio Ikeda, Kentaro Deguchi, Koji Ab. Mitochondrial fusion and fission proteins expression dynamically change in a murine model of amyotrophic lateral sclerosis. Current neurovascular research. vol 10. issue 3. 2014-03-13. PMID:23713734. |
in transgenic (tg) mice with the g93a human sod1 mutation (g93asod1), both mitochondrial fusion proteins (mfn1 and opal) and fission proteins (drp1 and fis1) showed a significant increase in the anterior half of the lumbar spinal cord. |
2014-03-13 |
2023-08-12 |
mouse |
| Laura Mòdol, Renzo Mancuso, Albert Alé, Isaac Francos-Quijorna, Xavier Navarr. Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons. Frontiers in cellular neuroscience. vol 8. 2014-01-30. PMID:24478630. |
moreover, 5-ht fibers were increased in the ventral horn of the lumbar spinal cord at late stage of disease progression in sod1(g93a) mice. |
2014-01-30 |
2023-08-12 |
mouse |
| Giovanni Nardo, Raffaele Iennaco, Nicolò Fusi, Paul R Heath, Marianna Marino, Maria C Trolese, Laura Ferraiuolo, Neil Lawrence, Pamela J Shaw, Caterina Bendott. Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis. Brain : a journal of neurology. vol 136. issue Pt 11. 2013-12-31. PMID:24065725. |
lumbar spinal motor neurons from the two sod1(g93a) mouse strains were isolated by laser capture microdissection and transcriptome analysis was conducted at four stages of disease. |
2013-12-31 |
2023-08-12 |
mouse |
| Gabriela P de Oliveira, Chrystian J Alves, Gerson Chad. Early gene expression changes in spinal cord from SOD1(G93A) Amyotrophic Lateral Sclerosis animal model. Frontiers in cellular neuroscience. vol 7. 2013-12-04. PMID:24302897. |
in order to identify als early events, we performed a microarray analysis employing a whole mouse genome platform to evaluate the gene expression pattern of lumbar spinal cords of transgenic sod1(g93a) mice and their littermate controls at pre-symptomatic ages of 40 and 80 days. |
2013-12-04 |
2023-08-12 |
mouse |
| Elodie Martin, William Cazenave, Daniel Cattaert, Pascal Brancherea. Embryonic alteration of motoneuronal morphology induces hyperexcitability in the mouse model of amyotrophic lateral sclerosis. Neurobiology of disease. vol 54. 2013-10-21. PMID:23466698. |
here, using transgenic mice overexpressing the g93a mutation of the human cu/zn superoxide dismutase gene (sod1), we show that sod1(g93a) embryonic lumbar e17.5 mns already expressed abnormal morphometric parameters, including a deep reduction of their terminal segments length. |
2013-10-21 |
2023-08-12 |
mouse |