All Relations between slc1a1 and glutamate

Publication Sentence Publish Date Extraction Date Species
Yoshikatsu Kanai, Matthias A Hedige. The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects. Pflugers Archiv : European journal of physiology. vol 447. issue 5. 2004-09-03. PMID:14530974. selective inhibition of the neuronal glutamate transporter eaac1 (slc1a1) may be of therapeutic interest to block glutamate release from neurons during ischemia. 2004-09-03 2023-08-12 Not clear
Yoshikatsu Kanai, Matthias A Hedige. The glutamate and neutral amino acid transporter family: physiological and pharmacological implications. European journal of pharmacology. vol 479. issue 1-3. 2004-07-20. PMID:14612154. selective inhibition of the neuronal glutamate transporter eaac1 (slc1a1) but not the glial glutamate transporters may be of therapeutic interest, allowing blockage of glutamate exit from neurons due to "reversed glutamate transport" of eaac1, which will occur during pathological conditions, such as during ischemia after a stroke. 2004-07-20 2023-08-12 mouse
J Veenstra-VanderWeele, S J Kim, D Gonen, G L Hanna, B L Leventhal, E H Coo. Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder. Molecular psychiatry. vol 6. issue 2. 2001-06-28. PMID:11317217. the first genome scan conducted in early-onset obsessive-compulsive disorder used a non-parametric analysis to identify a peak in a region of chromosome 9 containing the gene slc1a1, which codes for the neuronal and epithelial glutamate transporter eaac1. 2001-06-28 2023-08-12 Not clear