| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M G Bianchi, R Franchi-Gazzola, L Reia, M Allegri, J Uggeri, M Chiu, R Sala, O Bussolat. Valproic acid induces the glutamate transporter excitatory amino acid transporter-3 in human oligodendroglioma cells. Neuroscience. vol 227. 2013-05-09. PMID:23041758. |
however, in these cells, but not in u373 human glioblastoma cells, valproic acid (vpa), an inhibitor of histone deacetylases, markedly induces slc1a1 mrna, which encodes for the glutamate transporter eaat3. |
2013-05-09 |
2023-08-12 |
human |
| Frederike Schirmbeck, Vanessa Nieratschker, Josef Frank, Susanne Englisch, Franziska Rausch, Andreas Meyer-Lindenberg, Marcella Rietschel, Mathias Zin. Polymorphisms in the glutamate transporter gene SLC1A1 and obsessive-compulsive symptoms induced by second-generation antipsychotic agents. Psychiatric genetics. vol 22. issue 5. 2013-04-23. PMID:22531293. |
polymorphisms in the glutamate transporter gene slc1a1 and obsessive-compulsive symptoms induced by second-generation antipsychotic agents. |
2013-04-23 |
2023-08-12 |
Not clear |
| Frederike Schirmbeck, Vanessa Nieratschker, Josef Frank, Susanne Englisch, Franziska Rausch, Andreas Meyer-Lindenberg, Marcella Rietschel, Mathias Zin. Polymorphisms in the glutamate transporter gene SLC1A1 and obsessive-compulsive symptoms induced by second-generation antipsychotic agents. Psychiatric genetics. vol 22. issue 5. 2013-04-23. PMID:22531293. |
a genetic risk factor for these secondary ocs was recently described in the gene slc1a1 encoding the neuronal glutamate transporter excitatory amino acid carrier 1. |
2013-04-23 |
2023-08-12 |
Not clear |
| Fuller W Bazer, Jinyoung Kim, Hakhyun Ka, Gregory A Johnson, Guoyao Wu, Gwonhwa Son. Select nutrients in the uterine lumen of sheep and pigs affect conceptus development. The Journal of reproduction and development. vol 58. issue 2. 2012-10-29. PMID:22738901. |
transporters for glutamate and neutral (slc1a1, slc1a4) and cationic (slc7a1, slc7a2, slc7a7, slc7a9) amino acids are expressed in uterine le and slc7a3 mrna is expressed in conceptus tr. |
2012-10-29 |
2023-08-12 |
Not clear |
| Ke Wu, Gregory L Hanna, David R Rosenberg, Paul D Arnol. The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder. Pharmacology, biochemistry, and behavior. vol 100. issue 4. 2012-05-01. PMID:22024159. |
third, candidate gene studies have identified associations between variants in glutamate system genes and ocd, particularly for slc1a1 which has been shown to be associated with ocd in five independent studies. |
2012-05-01 |
2023-08-12 |
mouse |
| Yasue Horiuchi, Syuhei Iida, Minori Koga, Hiroki Ishiguro, Yoshimi Iijima, Toshiya Inada, Yuichiro Watanabe, Toshiyuki Someya, Hiroshi Ujike, Nakao Iwata, Norio Ozaki, Hiroshi Kunugi, Mamoru Tochigi, Masanari Itokawa, Makoto Arai, Kazuhiro Niizato, Shuji Iritani, Akiyoshi Kakita, Hitoshi Takahashi, Hiroyuki Nawa, Tadao Arinam. Association of SNPs linked to increased expression of SLC1A1 with schizophrenia. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 1. 2012-04-19. PMID:22095641. |
the slc1a1 gene located at 9p24 encodes the glutamate transporter eaat3/eaac1. |
2012-04-19 |
2023-08-12 |
human |
| Seunghyong Ryu, Sohee Oh, Eun-Young Cho, Hee Jung Nam, Jae Hyun Yoo, Taesung Park, Yeon Ho Joo, Jun Soo Kwon, Kyung Sue Hon. Interaction between genetic variants of DLGAP3 and SLC1A1 affecting the risk of atypical antipsychotics-induced obsessive-compulsive symptoms. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 156B. issue 8. 2012-02-14. PMID:21990008. |
furthermore, we explored the interactions between dlgap3 and a previously reported susceptibility gene, the glutamate transporter gene slc1a1, regarding this phenotype. |
2012-02-14 |
2023-08-12 |
human |
| Jennifer T Wolstenholme, Julia A Taylor, Savera R J Shetty, Michelle Edwards, Jessica J Connelly, Emilie F Rissma. Gestational exposure to low dose bisphenol A alters social behavior in juvenile mice. PloS one. vol 6. issue 9. 2012-01-26. PMID:21980460. |
interestingly, mrna for the glutamate transporter, slc1a1, was enhanced by exposure to bpa in female brains. |
2012-01-26 |
2023-08-12 |
mouse |
| Jack Samuels, Ying Wang, Mark A Riddle, Benjamin D Greenberg, Abby J Fyer, James T McCracken, Scott L Rauch, Dennis L Murphy, Marco A Grados, James A Knowles, John Piacentini, Bernadette Cullen, O Joseph Bienvenu, Steven A Rasmussen, Daniel Geller, David L Pauls, Kung-Yee Liang, Yin Y Shugart, Gerald Nestad. Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 156B. issue 4. 2011-09-28. PMID:21445956. |
comprehensive family-based association study of the glutamate transporter gene slc1a1 in obsessive-compulsive disorder. |
2011-09-28 |
2023-08-12 |
human |
| Jack Samuels, Ying Wang, Mark A Riddle, Benjamin D Greenberg, Abby J Fyer, James T McCracken, Scott L Rauch, Dennis L Murphy, Marco A Grados, James A Knowles, John Piacentini, Bernadette Cullen, O Joseph Bienvenu, Steven A Rasmussen, Daniel Geller, David L Pauls, Kung-Yee Liang, Yin Y Shugart, Gerald Nestad. Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 156B. issue 4. 2011-09-28. PMID:21445956. |
slc1a1 encodes a neuronal glutamate transporter and is a promising candidate gene for obsessive-compulsive disorder (ocd). |
2011-09-28 |
2023-08-12 |
human |
| Charles G Bailey, Renae M Ryan, Annora D Thoeng, Cynthia Ng, Kara King, Jessica M Vanslambrouck, Christiane Auray-Blais, Robert J Vandenberg, Stefan Bröer, John E J Rask. Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. The Journal of clinical investigation. vol 121. issue 1. 2011-02-03. PMID:21123949. |
loss-of-function mutations in the glutamate transporter slc1a1 cause human dicarboxylic aminoaciduria. |
2011-02-03 |
2023-08-12 |
human |
| Charles G Bailey, Renae M Ryan, Annora D Thoeng, Cynthia Ng, Kara King, Jessica M Vanslambrouck, Christiane Auray-Blais, Robert J Vandenberg, Stefan Bröer, John E J Rask. Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. The Journal of clinical investigation. vol 121. issue 1. 2011-02-03. PMID:21123949. |
solute carrier family 1, member 1 (slc1a1; also known as eaat3 and eaac1) is the major epithelial transporter of glutamate and aspartate in the kidneys and intestines of rodents. |
2011-02-03 |
2023-08-12 |
human |
| Charles G Bailey, Renae M Ryan, Annora D Thoeng, Cynthia Ng, Kara King, Jessica M Vanslambrouck, Christiane Auray-Blais, Robert J Vandenberg, Stefan Bröer, John E J Rask. Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. The Journal of clinical investigation. vol 121. issue 1. 2011-02-03. PMID:21123949. |
within the brain, slc1a1 serves as the predominant neuronal glutamate transporter and buffers the synaptic release of the excitatory neurotransmitter glutamate within the interneuronal synaptic cleft. |
2011-02-03 |
2023-08-12 |
human |
| Charles G Bailey, Renae M Ryan, Annora D Thoeng, Cynthia Ng, Kara King, Jessica M Vanslambrouck, Christiane Auray-Blais, Robert J Vandenberg, Stefan Bröer, John E J Rask. Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. The Journal of clinical investigation. vol 121. issue 1. 2011-02-03. PMID:21123949. |
here we report that slc1a1 mutations leading to substitution of arginine to tryptophan at position 445 (r445w) and deletion of isoleucine at position 395 (i395del) cause human dicarboxylic aminoaciduria, an autosomal recessive disorder of urinary glutamate and aspartate transport that can be associated with mental retardation. |
2011-02-03 |
2023-08-12 |
human |
| Charles G Bailey, Renae M Ryan, Annora D Thoeng, Cynthia Ng, Kara King, Jessica M Vanslambrouck, Christiane Auray-Blais, Robert J Vandenberg, Stefan Bröer, John E J Rask. Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. The Journal of clinical investigation. vol 121. issue 1. 2011-02-03. PMID:21123949. |
these mutations of conserved residues impeded or abrogated glutamate and cysteine transport by slc1a1 and led to near-absent surface expression in a canine kidney cell line. |
2011-02-03 |
2023-08-12 |
human |
| Charles G Bailey, Renae M Ryan, Annora D Thoeng, Cynthia Ng, Kara King, Jessica M Vanslambrouck, Christiane Auray-Blais, Robert J Vandenberg, Stefan Bröer, John E J Rask. Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. The Journal of clinical investigation. vol 121. issue 1. 2011-02-03. PMID:21123949. |
these findings provide evidence that slc1a1 is the major renal transporter of glutamate and aspartate in humans and implicate slc1a1 in the pathogenesis of some neurological disorders. |
2011-02-03 |
2023-08-12 |
human |
| Y Wang, A Adamczyk, Y Y Shugart, J F Samuels, M A Grados, B D Greenberg, J A Knowles, J T McCracken, S L Rauch, D L Murphy, S A Rasmussen, B Cullen, A Pinto, A J Fyer, J Piacentini, D L Pauls, O J Bienvenu, M Riddle, K Y Liang, D Valle, T Wang, G Nestad. A screen of SLC1A1 for OCD-related alleles. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 153B. issue 2. 2010-12-20. PMID:19569082. |
slc1a1, which encodes the neuronal and epithelial glutamate transporter, is a promising candidate gene for obsessive-compulsive disorder (ocd). |
2010-12-20 |
2023-08-12 |
human |
| Kenneth D Gadow, Jasmin Roohi, Carla J DeVincent, Sarah Kirsch, Eli Hatchwel. Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. Journal of autism and developmental disorders. vol 40. issue 9. 2010-11-30. PMID:20155310. |
glutamate transporter gene (slc1a1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. |
2010-11-30 |
2023-08-12 |
Not clear |
| Kenneth D Gadow, Jasmin Roohi, Carla J DeVincent, Sarah Kirsch, Eli Hatchwel. Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. Journal of autism and developmental disorders. vol 40. issue 9. 2010-11-30. PMID:20155310. |
investigated association of single nucleotide polymorphism (snp) rs301430 in glutamate transporter gene (slc1a1) with severity of repetitive behaviors (obsessive-compulsive behaviors, tics) and anxiety in children with autism spectrum disorder (asd). |
2010-11-30 |
2023-08-12 |
Not clear |
| Susanne Walitza, Jens R Wendland, Edna Gruenblatt, Andreas Warnke, Thomas A Sontag, Oliver Tucha, Klaus W Lang. Genetics of early-onset obsessive-compulsive disorder. European child & adolescent psychiatry. vol 19. issue 3. 2010-06-14. PMID:20213231. |
analyses of candidate genes in linkage regions have not provided evidence for their involvement in ocd, with the exception of the glutamate transporter gene slc1a1 on 9p24. |
2010-06-14 |
2023-08-12 |
Not clear |