| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacek Krol, Volker Busskamp, Ilona Markiewicz, Michael B Stadler, Sebastian Ribi, Jens Richter, Jens Duebel, Silvia Bicker, Hans Jörg Fehling, Dirk Schübeler, Thomas G Oertner, Gerhard Schratt, Miriam Bibel, Botond Roska, Witold Filipowic. Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell. vol 141. issue 4. 2010-05-20. PMID:20478254. |
we identified the voltage-dependent glutamate transporter slc1a1 as one of the mir-183/96/182 targets in photoreceptor cells. |
2010-05-20 |
2023-08-12 |
mouse |
| J Y Rotge, B Aouizerate, J Tignol, B Bioulac, P Burbaud, D Gueh. The glutamate-based genetic immune hypothesis in obsessive-compulsive disorder. An integrative approach from genes to symptoms. Neuroscience. vol 165. issue 2. 2010-02-24. PMID:19861150. |
in particular, the glutamate transporter gene slc1a1 has been associated with the diagnosis of ocd. |
2010-02-24 |
2023-08-12 |
Not clear |
| Y Y Shugart, Y Wang, J F Samuels, M A Grados, B D Greenberg, J A Knowles, J T McCracken, S L Rauch, D L Murphy, S A Rasmussen, B Cullen, R Hoehn-Saric, A Pinto, A J Fyer, J Piacentini, D L Pauls, O J Bienvenu, M A Riddle, K Y Liang, G Nestad. A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 150B. issue 6. 2009-11-23. PMID:19152386. |
a family-based association study of the glutamate transporter gene slc1a1 in obsessive-compulsive disorder in 378 families. |
2009-11-23 |
2023-08-12 |
Not clear |
| Jun Soo Kwon, Yeon Ho Joo, Hee Jung Nam, Meerae Lim, Eun-Young Cho, Myung Hun Jung, Jung-Seok Choi, Byungsu Kim, Do-Hyung Kang, Sohee Oh, Taesung Park, Kyung Sue Hon. Association of the glutamate transporter gene SLC1A1 with atypical antipsychotics-induced obsessive-compulsive symptoms. Archives of general psychiatry. vol 66. issue 11. 2009-11-12. PMID:19884611. |
association of the glutamate transporter gene slc1a1 with atypical antipsychotics-induced obsessive-compulsive symptoms. |
2009-11-12 |
2023-08-12 |
Not clear |
| Jun Soo Kwon, Yeon Ho Joo, Hee Jung Nam, Meerae Lim, Eun-Young Cho, Myung Hun Jung, Jung-Seok Choi, Byungsu Kim, Do-Hyung Kang, Sohee Oh, Taesung Park, Kyung Sue Hon. Association of the glutamate transporter gene SLC1A1 with atypical antipsychotics-induced obsessive-compulsive symptoms. Archives of general psychiatry. vol 66. issue 11. 2009-11-12. PMID:19884611. |
the glutamate transporter gene slc1a1, which was recently reported to be associated with obsessive-compulsive disorder (ocd), is a promising candidate gene for susceptibility to aap-induced oc symptoms. |
2009-11-12 |
2023-08-12 |
Not clear |
| Camille W Brune, Soo-Jeong Kim, Gregory L Hanna, Eric Courchesne, Catherine Lord, Bennett L Leventhal, Edwin H Coo. Family-Based Association Testing of OCD-associated SNPs of SLC1A1 in an autism sample. Autism research : official journal of the International Society for Autism Research. vol 1. issue 2. 2009-07-13. PMID:19360657. |
reports identified the neuronal glutamate transporter gene, slc1a1 (omim 133550, chromosome 9p24), as a positional and functional candidate gene for obsessive-compulsive disorder (ocd). |
2009-07-13 |
2023-08-12 |
Not clear |
| Camille W Brune, Soo-Jeong Kim, Gregory L Hanna, Eric Courchesne, Catherine Lord, Bennett L Leventhal, Edwin H Coo. Family-Based Association Testing of OCD-associated SNPs of SLC1A1 in an autism sample. Autism research : official journal of the International Society for Autism Research. vol 1. issue 2. 2009-07-13. PMID:19360657. |
the presence of obsessions and compulsions similar to ocd in autism, the identification of this region in a genome-wide linkage analysis of individuals with autism spectrum disorders (asds), and the hypothesized role of glutamate in asds make slc1a1 a candidate gene for asd as well. |
2009-07-13 |
2023-08-12 |
Not clear |
| Kevin Duerson, Randall L Woltjer, Paramita Mookherjee, James B Leverenz, Thomas J Montine, Thomas D Bird, David V Pow, Thomas Rauen, David G Coo. Detergent-insoluble EAAC1/EAAT3 aberrantly accumulates in hippocampal neurons of Alzheimer's disease patients. Brain pathology (Zurich, Switzerland). vol 19. issue 2. 2009-05-01. PMID:18624794. |
eaac1 (also called eaat3 or slc1a1) is the primary glutamate transporter in forebrain neurons. |
2009-05-01 |
2023-08-12 |
human |
| Jens R Wendland, Pablo R Moya, Kiara R Timpano, Adriana P Anavitarte, Matthew R Kruse, Michael G Wheaton, Renee F Ren-Patterson, Dennis L Murph. A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. Archives of general psychiatry. vol 66. issue 4. 2009-04-22. PMID:19349310. |
recent evidence from linkage analyses and follow-up candidate gene studies supports the involvement of slc1a1, which encodes the neuronal glutamate transporter, in the development of obsessive-compulsive disorder (ocd). |
2009-04-22 |
2023-08-12 |
Not clear |
| Kung-Yee Liang, Ying Wang, Yin Yao Shugart, Marco Grados, Abby J Fyer, Scott Rauch, Dennis Murphy, James McCracken, Steven Rasmussen, Bernadette Cullen, Rudolf Hoehn-Saric, Benjamin Greenberg, Anthony Pinto, James Knowles, John Piacentini, David Pauls, O Bienvenu, Mark Riddle, Jack Samuels, Gerald Nestad. Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18286588. |
slc1a1, a glutamate transporter gene on chromosome 9p, was originally proposed to be related to ocd based on two linkage studies, and subsequently association of ocd to the gene has been replicated. |
2008-12-04 |
2023-08-12 |
Not clear |
| S Evelyn Stewart, Jesen A Fagerness, Jill Platko, Jordan W Smoller, Jeremiah M Scharf, Cornelia Illmann, Eric Jenike, Nadia Chabane, Marion Leboyer, Richard Delorme, Michael A Jenike, David L Paul. Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 8. 2008-02-05. PMID:17894418. |
association of the slc1a1 glutamate transporter gene and obsessive-compulsive disorder. |
2008-02-05 |
2023-08-12 |
Not clear |
| S Evelyn Stewart, Jesen A Fagerness, Jill Platko, Jordan W Smoller, Jeremiah M Scharf, Cornelia Illmann, Eric Jenike, Nadia Chabane, Marion Leboyer, Richard Delorme, Michael A Jenike, David L Paul. Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 8. 2008-02-05. PMID:17894418. |
two separate proximal haplotypes in the glutamate transporter gene, slc1a1, were recently reported to be associated with ocd among males, but replication is required. |
2008-02-05 |
2023-08-12 |
Not clear |
| Marco Grados, Holly C Wilco. Genetics of obsessive-compulsive disorder: a research update. Expert review of neurotherapeutics. vol 7. issue 8. 2007-09-10. PMID:17678492. |
finally, candidate gene studies, while promising, are not yet associated with linkage regions, except in the case of the glutamate transporter gene slc1a1 in 9p24. |
2007-09-10 |
2023-08-12 |
Not clear |
| Xiangdong Deng, Hiroki Shibata, Naoko Takeuchi, Shinako Rachi, Mayumi Sakai, Hideaki Ninomiya, Nakao Iwata, Norio Ozaki, Yasuyuki Fukumak. Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 3. 2007-07-18. PMID:17221839. |
association study of polymorphisms in the glutamate transporter genes slc1a1, slc1a3, and slc1a6 with schizophrenia. |
2007-07-18 |
2023-08-12 |
Not clear |
| Xiangdong Deng, Hiroki Shibata, Naoko Takeuchi, Shinako Rachi, Mayumi Sakai, Hideaki Ninomiya, Nakao Iwata, Norio Ozaki, Yasuyuki Fukumak. Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 3. 2007-07-18. PMID:17221839. |
we report here association studies of schizophrenia with three glutamate transporter genes slc1a1, slc1a3, and slc1a6 encoding the glutamate transporters eaat3, eaat1, and eaat4, respectively. |
2007-07-18 |
2023-08-12 |
Not clear |
| Rexhep Rexhepaj, Florian Grahammer, Harald Völkl, Christine Remy, Carsten A Wagner, Diana Sandulache, Ferruh Artunc, Guido Henke, Srinivas Nammi, Giovambattista Capasso, Dario R Alessi, Florian Lan. Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 13. 2006-11-27. PMID:17077298. |
according to immunoblotting of brush border membrane proteins prepared from kidney, expression of the na+-dependent neutral amino acid transporter b(0)at1 (slc6a19), the glutamate transporter eaac1/eaat3 (slc1a1), and the transporter for cationic amino acids and cystine b(0,+)at (slc7a9) was decreased but the na+/proline cotransporter sit (slc6a20) was increased in pdk1(hm) mice. |
2006-11-27 |
2023-08-12 |
mouse |
| Paul Daniel Arnold, Tricia Sicard, Eliza Burroughs, Margaret A Richter, James L Kenned. Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. Archives of general psychiatry. vol 63. issue 7. 2006-08-03. PMID:16818866. |
glutamate transporter gene slc1a1 associated with obsessive-compulsive disorder. |
2006-08-03 |
2023-08-12 |
Not clear |
| Paul Daniel Arnold, Tricia Sicard, Eliza Burroughs, Margaret A Richter, James L Kenned. Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder. Archives of general psychiatry. vol 63. issue 7. 2006-08-03. PMID:16818866. |
this region contains the gene encoding the neuronal glutamate transporter, slc1a1. |
2006-08-03 |
2023-08-12 |
Not clear |
| Diane E Dickel, Jeremy Veenstra-VanderWeele, Nancy J Cox, Xiaolin Wu, Daniel J Fischer, Michelle Van Etten-Lee, Joseph A Himle, Bennett L Leventhal, Edwin H Cook, Gregory L Hann. Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder. Archives of general psychiatry. vol 63. issue 7. 2006-08-03. PMID:16818867. |
the glutamate transporter gene solute carrier family 1, member 1 (slc1a1) is a promising functional candidate in this region because altered glutamatergic concentrations have been found in the striatum and anterior cingulate in neuroimaging studies of pediatric ocd. |
2006-08-03 |
2023-08-12 |
Not clear |
| Yoshikatsu Kanai, Matthias A Hedige. The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects. Pflugers Archiv : European journal of physiology. vol 447. issue 5. 2004-09-03. PMID:14530974. |
the solute carrier family 1 (slc1) includes five high-affinity glutamate transporters, eaac1, glt-1, glast, eaat4 and eaat5 (slc1a1, slc1a2, slc1a3, slc1a6, and slc1a7, respectively) as well as the two neutral amino acid transporters, asct1 and asct2 (slc1a4 and alc1a5, respectively). |
2004-09-03 |
2023-08-12 |
Not clear |