| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Zhang, Hao-Yan Wang, Da-Li Wang, Xiao-Dong Zhan. Effect of pressure therapy for treatment of hypertrophic scar. Medicine. vol 98. issue 26. 2019-07-08. PMID:31261594. |
pressure therapy (pst) has been reported for the treatment of hypertrophic scar (hs) effectively. |
2019-07-08 |
2023-08-13 |
Not clear |
| Kathryn Potter, Sailesh Konda, Vicky Zhen Ren, Apphia Lihan Wang, Aditya Srinivasan, Suneel Chilukur. Techniques for Optimizing Surgical Scars, Part 2: Hypertrophic Scars and Keloids. Skinmed. vol 15. issue 6. 2019-07-08. PMID:29282183. |
part 2 focuses on scar revision for hypertrophic and keloids scars. |
2019-07-08 |
2023-08-13 |
Not clear |
| Kathryn Potter, Sailesh Konda, Vicky Zhen Ren, Apphia Lihan Wang, Aditya Srinivasan, Suneel Chilukur. Techniques for Optimizing Surgical Scars, Part 2: Hypertrophic Scars and Keloids. Skinmed. vol 15. issue 6. 2019-07-08. PMID:29282183. |
scar revision options for hypertrophic and keloid scars include corticosteroids, bleomycin, fluorouracil, verapamil, avotermin, hydrogel scaffold, nonablative fractional lasers, ablative and fractional ablative lasers, pulsed dye laser (pdl), flurandrenolide tape, imiquimod, onion extract, silicone, and scar massage. |
2019-07-08 |
2023-08-13 |
Not clear |
| Julei Zhang, Qiao Qiao, Mengdong Liu, Ting He, Jihong Shi, Xiaozhi Bai, Yijie Zhang, Yan Li, Weixia Cai, Shichao Han, Hao Guan, Dahai H. IL-17 Promotes Scar Formation by Inducing Macrophage Infiltration. The American journal of pathology. vol 188. issue 7. 2019-07-05. PMID:29753790. |
trauma or burn injuries that affect the deep dermis often produce a hypertrophic scar, which limits patients' joint movement and generates an aesthetic problem. |
2019-07-05 |
2023-08-13 |
mouse |
| Julei Zhang, Qiao Qiao, Mengdong Liu, Ting He, Jihong Shi, Xiaozhi Bai, Yijie Zhang, Yan Li, Weixia Cai, Shichao Han, Hao Guan, Dahai H. IL-17 Promotes Scar Formation by Inducing Macrophage Infiltration. The American journal of pathology. vol 188. issue 7. 2019-07-05. PMID:29753790. |
we found that il-17 was increased in scar tissues from patients with hypertrophic scar compared with normal skin. |
2019-07-05 |
2023-08-13 |
mouse |
| Maria J Kowzun, William J Rifkin, Zachary M Borab, Trevor Ellison, Marc A Soares, Stelios C Wilson, Philip Lotfi, Amey Bandekar, Stavroula Sofou, Pierre B Saadeh, Daniel J Ceradin. Topical inhibition of PUMA signaling mitigates radiation injury. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 6. 2019-06-27. PMID:30155987. |
skin was harvested at multiple time points to evaluate dermal sirna penetration, mrna expression, protein expression, dermal thickness, subcutaneous fat, stiffness, vascular hypertrophy, scar index, and reactive oxygen species (ros) generation. |
2019-06-27 |
2023-08-13 |
mouse |
| Maria J Kowzun, William J Rifkin, Zachary M Borab, Trevor Ellison, Marc A Soares, Stelios C Wilson, Philip Lotfi, Amey Bandekar, Stavroula Sofou, Pierre B Saadeh, Daniel J Ceradin. Topical inhibition of PUMA signaling mitigates radiation injury. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 6. 2019-06-27. PMID:30155987. |
tissue stiffness, dermal thickness, vascular hypertrophy, scar index, ros levels, and mrna levels of mnsod and tgf-β were all significantly reduced with sipuma treatment compared to nonsense controls. |
2019-06-27 |
2023-08-13 |
mouse |
| Sander Kant, Eric van den Kerckhove, Carlo Colla, René van der Hulst, Andrzej Piatkowski de Grzymal. Duration of Scar Maturation: Retrospective Analyses of 361 Hypertrophic Scars Over 5 Years. Advances in skin & wound care. vol 32. issue 1. 2019-06-21. PMID:30531549. |
duration of scar maturation: retrospective analyses of 361 hypertrophic scars over 5 years. |
2019-06-21 |
2023-08-13 |
Not clear |
| Long Xiao, Tianyi Tang, Yu Huang, Jianxing Gu. MiR-564 promotes hypertrophic scar formation through TGF-β1 upregulation. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. vol 154. issue 2. 2019-06-19. PMID:28933518. |
mir-564 promotes hypertrophic scar formation through tgf-β1 upregulation. |
2019-06-19 |
2023-08-13 |
Not clear |
| Long Xiao, Tianyi Tang, Yu Huang, Jianxing Gu. MiR-564 promotes hypertrophic scar formation through TGF-β1 upregulation. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. vol 154. issue 2. 2019-06-19. PMID:28933518. |
to evaluate the role of microrna564 (mir-564) in the development of hypertrophic scar and investigate the possible mechanism of this process. |
2019-06-19 |
2023-08-13 |
Not clear |
| Jihong Shi, Houan Xiao, Jun Li, Julei Zhang, Yan Li, Jian Zhang, Xujie Wang, Xiaozhi Bai, Ke Tao, Dahai Hu, Hao Gua. Wild-type p53-modulated autophagy and autophagic fibroblast apoptosis inhibit hypertrophic scar formation. Laboratory investigation; a journal of technical methods and pathology. vol 98. issue 11. 2019-06-13. PMID:30089855. |
wild-type p53-modulated autophagy and autophagic fibroblast apoptosis inhibit hypertrophic scar formation. |
2019-06-13 |
2023-08-13 |
rabbit |
| Jihong Shi, Houan Xiao, Jun Li, Julei Zhang, Yan Li, Jian Zhang, Xujie Wang, Xiaozhi Bai, Ke Tao, Dahai Hu, Hao Gua. Wild-type p53-modulated autophagy and autophagic fibroblast apoptosis inhibit hypertrophic scar formation. Laboratory investigation; a journal of technical methods and pathology. vol 98. issue 11. 2019-06-13. PMID:30089855. |
hypertrophic scarring is a serious fibrotic skin disease, and the abnormal activation of hypertrophic scar fibroblasts (hsfs) intensifies its pathogenesis. |
2019-06-13 |
2023-08-13 |
rabbit |
| Farrukh Aslam Khalid, Muhammad Younas Mehrose, Muhammad Saleem, Muhammad Amin Yousaf, Abdul Malik Mujahid, Saif Ur Rehman, Sania Ahmad, Moazzam Nazeer Tara. Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. Burns : journal of the International Society for Burn Injuries. vol 45. issue 1. 2019-06-10. PMID:30340861. |
the treatment of keloid and hypertrophic scar is challenging with no universally accepted mode for permanent ablation. |
2019-06-10 |
2023-08-13 |
Not clear |
| Bernadette Nedelec, Marie-Andrée Couture, Valerie Calva, Chantal Poulin, Annick Chouinard, Danielle Shashoua, Nathalie Gauthier, José A Correa, Ana de Oliveira, Barbara Mazer, Leo LaSall. Randomized controlled trial of the immediate and long-term effect of massage on adult postburn scar. Burns : journal of the International Society for Burn Injuries. vol 45. issue 1. 2019-06-10. PMID:30626496. |
one objective of massage therapy applied to hypertrophic scar (hsc), is to improve the structural properties so skin possesses the strength and elasticity required for normal mobility. |
2019-06-10 |
2023-08-13 |
Not clear |
| Jorge L Medina, Eliza A Sebastian, Andrea B Fourcaudot, Rossella Dorati, Kai P Leun. Pirfenidone Ointment Modulates the Burn Wound Bed in C57BL/6 Mice by Suppressing Inflammatory Responses. Inflammation. vol 42. issue 1. 2019-06-03. PMID:30120654. |
the high incidence of hypertrophic scar formation is one of the many challenges to treating deep partial-thickness burns. |
2019-06-03 |
2023-08-13 |
mouse |
| Zheng Zhang, Ying Liu, Yunsheng Chen, Lexiang Li, Ping Lan, Dannong He, Jie Song, Yixin Zhan. Transdermal Delivery of 5-Aminolevulinic Acid by Nanoethosome Gels for Photodynamic Therapy of Hypertrophic Scars. ACS applied materials & interfaces. vol 11. issue 4. 2019-06-03. PMID:30589527. |
in vivo delivery studies further reveal that ala-es gels can penetrate into rabbit hs tissue to facilitate ala accumulating in hypertrophic scar fibroblast (hsf) and converting into protoporphyrin ix in the cytoplasm. |
2019-06-03 |
2023-08-13 |
human |
| Amina El Ayadi, Anesh Prasai, Ye Wang, David N Herndon, Celeste C Finnert. β-Adrenergic Receptor Trafficking, Degradation, and Cell Surface Expression Are Altered in Dermal Fibroblasts from Hypertrophic Scars. The Journal of investigative dermatology. vol 138. issue 7. 2019-05-22. PMID:29476776. |
we investigated the effect of burn injury on β1-, β2-, and β3-ar expression, trafficking, and degradation in human dermal fibroblasts from hypertrophic scar [hsf], non-scar fibroblasts, and normal fibroblasts. |
2019-05-22 |
2023-08-13 |
human |
| Yi Zhang, Li Zhang, Qiyu Zhang, Weilong Hong, Xiaohua Li. [microRNA-222 regulates proliferation and apoptosis of fibroblasts in hypertrophic scar via matrix metalloproteinase 1]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 46. issue 6. 2019-05-20. PMID:29658663. |
[microrna-222 regulates proliferation and apoptosis of fibroblasts in hypertrophic scar via matrix metalloproteinase 1]. |
2019-05-20 |
2023-08-13 |
Not clear |
| Yi Zhang, Li Zhang, Qiyu Zhang, Weilong Hong, Xiaohua Li. [microRNA-222 regulates proliferation and apoptosis of fibroblasts in hypertrophic scar via matrix metalloproteinase 1]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 46. issue 6. 2019-05-20. PMID:29658663. |
objective: to explore the effect of microrna(mir)-222 on cell proliferation and apoptosis of fibroblasts in hypertrophic scar (hs) and the underlying mechanisms. |
2019-05-20 |
2023-08-13 |
Not clear |
| Shikha Chawla, Sourabh Ghos. Regulation of fibrotic changes by the synergistic effects of cytokines, dimensionality and matrix: Towards the development of an in vitro human dermal hypertrophic scar model. Acta biomaterialia. vol 69. 2019-05-08. PMID:29330036. |
regulation of fibrotic changes by the synergistic effects of cytokines, dimensionality and matrix: towards the development of an in vitro human dermal hypertrophic scar model. |
2019-05-08 |
2023-08-13 |
human |