| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao, Jung-Ju Huang, Zung-Chung Chen, Chee-Jen Chang, Lun-Jou Lo, Philip Kuo-Ting Chen, Jyh-Ping Chen, Yu-Ray Che. Clinical evaluation of silicone gel in the treatment of cleft lip scars. Scientific reports. vol 8. issue 1. 2019-10-11. PMID:29743500. |
hence, we sought to test whether silicone gel, which cannot be ingested whole, might be non-inferior to silicone sheeting for controlling against upper lip scar hypertrophy. |
2019-10-11 |
2023-08-13 |
Not clear |
| Wei Qian, Ning Li, Qian Cao, Jufeng Fa. Thrombospondin-4 critically controls transforming growth factor β1 induced hypertrophic scar formation. Journal of cellular physiology. vol 234. issue 1. 2019-10-04. PMID:30132849. |
thrombospondin-4 critically controls transforming growth factor β1 induced hypertrophic scar formation. |
2019-10-04 |
2023-08-13 |
rat |
| Wei Qian, Ning Li, Qian Cao, Jufeng Fa. Thrombospondin-4 critically controls transforming growth factor β1 induced hypertrophic scar formation. Journal of cellular physiology. vol 234. issue 1. 2019-10-04. PMID:30132849. |
transforming growth factor β (tgf-β) is a growth factor presenting important functions during tissue remodeling and hypertrophic scar (hs) formation. |
2019-10-04 |
2023-08-13 |
rat |
| Wei Qian, Ning Li, Qian Cao, Jufeng Fa. Thrombospondin-4 critically controls transforming growth factor β1 induced hypertrophic scar formation. Journal of cellular physiology. vol 234. issue 1. 2019-10-04. PMID:30132849. |
in this study, we identified thrombospondin-4 (tsp-4) as a tgf-β1 target that essentially mediates tgf-β1-induced scar formation both in vitro and in vivo. the expression of tsp-4 was compared on both mrna and protein levels between hypertrophic scar fibroblasts (hsfs) and normal skin fibroblast (nfs) in response to tgf-β1 treatment. |
2019-10-04 |
2023-08-13 |
rat |
| Hanneke N Monsuur, Lenie J van den Broek, Pieter Koolwijk, Frank B Niessen, Susan Gibb. Endothelial cells enhance adipose mesenchymal stromal cell-mediated matrix contraction via ALK receptors and reduced follistatin: Potential role of endothelial cells in skin fibrosis. Journal of cellular physiology. vol 233. issue 10. 2019-10-03. PMID:29345319. |
although several clinical risk factors have been described, the cross-talk between different cell types resulting in hypertrophic scar formation is still poorly understood. |
2019-10-03 |
2023-08-13 |
Not clear |
| Hanneke N Monsuur, Lenie J van den Broek, Pieter Koolwijk, Frank B Niessen, Susan Gibb. Endothelial cells enhance adipose mesenchymal stromal cell-mediated matrix contraction via ALK receptors and reduced follistatin: Potential role of endothelial cells in skin fibrosis. Journal of cellular physiology. vol 233. issue 10. 2019-10-03. PMID:29345319. |
the aim of this in vitro study was to investigate whether endothelial cells (ec) may play a role in skin fibrosis, for example, hypertrophic scar formation after full-thickness skin trauma. |
2019-10-03 |
2023-08-13 |
Not clear |
| Weizong Weng, Sisi He, Hongyuan Song, Xiaoqun Li, Liehu Cao, Yajie Hu, Jin Cui, Qirong Zhou, Huisheng Peng, Jiacan S. Aligned Carbon Nanotubes Reduce Hypertrophic Scar via Regulating Cell Behavior. ACS nano. vol 12. issue 8. 2019-09-30. PMID:30040897. |
aligned carbon nanotubes reduce hypertrophic scar via regulating cell behavior. |
2019-09-30 |
2023-08-13 |
rabbit |
| Weizong Weng, Sisi He, Hongyuan Song, Xiaoqun Li, Liehu Cao, Yajie Hu, Jin Cui, Qirong Zhou, Huisheng Peng, Jiacan S. Aligned Carbon Nanotubes Reduce Hypertrophic Scar via Regulating Cell Behavior. ACS nano. vol 12. issue 8. 2019-09-30. PMID:30040897. |
the capacity of the acnts to reduce hypertrophic scar formation was evaluated both in vitro and in vivo. |
2019-09-30 |
2023-08-13 |
rabbit |
| Weizong Weng, Sisi He, Hongyuan Song, Xiaoqun Li, Liehu Cao, Yajie Hu, Jin Cui, Qirong Zhou, Huisheng Peng, Jiacan S. Aligned Carbon Nanotubes Reduce Hypertrophic Scar via Regulating Cell Behavior. ACS nano. vol 12. issue 8. 2019-09-30. PMID:30040897. |
moreover, in vivo evaluation in a rabbit ear model indicated relieved scar hypertrophy after the acnts treatment. |
2019-09-30 |
2023-08-13 |
rabbit |
| b' Sokona Tour\\xc3\\xa9, Mahamadou Mall\\xc3\\xa. [Giant right post-traumatic retroauricular keloid]. The Pan African medical journal. vol 33. 2019-09-26. PMID:31448024.' |
a month after, pruritic hypertrophic scar occurred. |
2019-09-26 |
2023-08-13 |
human |
| Jingyun Li, Ling Chen, Qian Li, Jing Cao, Yanli Gao, Jun L. Comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. Journal of cellular physiology. vol 233. issue 8. 2019-09-23. PMID:29244193. |
comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. |
2019-09-23 |
2023-08-13 |
human |
| Jingyun Li, Ling Chen, Qian Li, Jing Cao, Yanli Gao, Jun L. Comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. Journal of cellular physiology. vol 233. issue 8. 2019-09-23. PMID:29244193. |
their roles in the pathogenesis of human hypertrophic scar remains poorly understood. |
2019-09-23 |
2023-08-13 |
human |
| Jingyun Li, Ling Chen, Qian Li, Jing Cao, Yanli Gao, Jun L. Comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. Journal of cellular physiology. vol 233. issue 8. 2019-09-23. PMID:29244193. |
in this study, we used liquid chromatography-tandem mass spectrometry to construct a comparative peptidomic profiling between human hypertrophic scar tissue and matched normal skin. |
2019-09-23 |
2023-08-13 |
human |
| Jingyun Li, Ling Chen, Qian Li, Jing Cao, Yanli Gao, Jun L. Comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. Journal of cellular physiology. vol 233. issue 8. 2019-09-23. PMID:29244193. |
a total of 179 peptides were significantly differentially expressed in human hypertrophic scar tissue, with 95 upregulated and 84 downregulated peptides between hypertrophic scar tissue and matched normal skin. |
2019-09-23 |
2023-08-13 |
human |
| Jingyun Li, Ling Chen, Qian Li, Jing Cao, Yanli Gao, Jun L. Comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. Journal of cellular physiology. vol 233. issue 8. 2019-09-23. PMID:29244193. |
further bioinformatics analysis (gene ontology and kyoto encyclopedia of genes and genomes pathway analysis) indicated that precursor proteins of these differentially expressed peptides correlate with cellular process, biological regulation, cell part, binding and structural molecule activity ribosome, and ppar signaling pathway occurring during pathological changes of hypertrophic scar. |
2019-09-23 |
2023-08-13 |
human |
| Jingyun Li, Ling Chen, Qian Li, Jing Cao, Yanli Gao, Jun L. Comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. Journal of cellular physiology. vol 233. issue 8. 2019-09-23. PMID:29244193. |
in conclusion, our results show significantly altered expression profiles of peptides in human hypertrophic scar tissue. |
2019-09-23 |
2023-08-13 |
human |
| Jingyun Li, Ling Chen, Qian Li, Jing Cao, Yanli Gao, Jun L. Comparative peptidomic profile between human hypertrophic scar tissue and matched normal skin for identification of endogenous peptides involved in scar pathology. Journal of cellular physiology. vol 233. issue 8. 2019-09-23. PMID:29244193. |
these peptides may participate in the etiology of hypertrophic scar and provide beneficial scheme for scar evaluation and treatments. |
2019-09-23 |
2023-08-13 |
human |
| Xiaojun Ji, Zhe Tang, Weiwei Shuai, Zhirui Zhang, Jingyun Li, Ling Chen, Jing Cao, Wu Yi. Endogenous peptide LYENRL prevents the activation of hypertrophic scar-derived fibroblasts by inhibiting the TGF-β1/Smad pathway. Life sciences. vol 231. 2019-09-19. PMID:31344427. |
hypertrophic scar formation is a fibroproliferative disorder caused by abnormal wound healing. |
2019-09-19 |
2023-08-13 |
Not clear |
| Xiaojun Ji, Zhe Tang, Weiwei Shuai, Zhirui Zhang, Jingyun Li, Ling Chen, Jing Cao, Wu Yi. Endogenous peptide LYENRL prevents the activation of hypertrophic scar-derived fibroblasts by inhibiting the TGF-β1/Smad pathway. Life sciences. vol 231. 2019-09-19. PMID:31344427. |
taken together, we concluded that the effects of lyenrl on scar fibroblasts make it a potential peptide drug for hypertrophic scar treatment. |
2019-09-19 |
2023-08-13 |
Not clear |
| Denis Ehrl, Paul I Heidekrueger, P Niclas Broer, Holger C Ern. Topical Negative Pressure Wound Therapy of Burned Hands: Functional Outcomes. Journal of burn care & research : official publication of the American Burn Association. vol 39. issue 1. 2019-09-18. PMID:28368916. |
regarding the quality of the scars of the hand, 41 hands showed good quality with no signs of hypertrophic scar formation and 6 hands showed acceptable quality of scars with partial hypertrophic scar formation. |
2019-09-18 |
2023-08-13 |
Not clear |