| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Johannes Matiasek, Philip Kienzl, Lukas W Unger, Christoph Grill, Rupert Koller, Bela R Tur. An intra-individual surgical wound comparison shows that octenidine-based hydrogel wound dressing ameliorates scar appearance following abdominoplasty. International wound journal. vol 15. issue 6. 2019-03-14. PMID:29956471. |
the octenidine-based wound dressing demonstrates improved wound healing associated with a lower incidence of hypertrophic scar formation. |
2019-03-14 |
2023-08-13 |
Not clear |
| Johanneke J J Akershoek, Katrien M Brouwer, Marcel Vlig, Bouke K H L Boekema, Rob H J Beelen, Esther Middelkoop, Magda M W Ulric. Early intervention by Captopril does not improve wound healing of partial thickness burn wounds in a rat model. Burns : journal of the International Society for Burn Injuries. vol 44. issue 2. 2019-03-14. PMID:29032968. |
prolonged and excessive inflammatory response is a major cause of hypertrophic scar formation in burns. |
2019-03-14 |
2023-08-13 |
rat |
| Yating Wei, Yan Wang, Ming Zhang, Gang Yan, Shixue Wu, Wenjun Liu, Gang Ji, Cecilia W P Li-Tsan. The application of 3D-printed transparent facemask for facial scar management and its biomechanical rationale. Burns : journal of the International Society for Burn Injuries. vol 44. issue 2. 2019-03-14. PMID:29032976. |
however, the effectiveness of the device and its biomechanical characteristics on pressure management of hypertrophic scar would need more objective evaluation. |
2019-03-14 |
2023-08-13 |
Not clear |
| Canser Yilmaz Demir, Muhammet Eren Ersoz, Remzi Erten, Omer Faruk Kocak, Yilmaz Sultanoglu, Yildiray Basbuga. Comparison of Enalapril, Candesartan and Intralesional Triamcinolone in Reducing Hypertrophic Scar Development: An Experimental Study. Aesthetic plastic surgery. vol 42. issue 2. 2019-03-01. PMID:29349667. |
comparison of enalapril, candesartan and intralesional triamcinolone in reducing hypertrophic scar development: an experimental study. |
2019-03-01 |
2023-08-13 |
Not clear |
| Yongqiang Xiao, Yu Sun, Banghui Zhu, Kangan Wang, Pengfei Liang, Wenjun Liu, Jinfeng Fu, Shiqing Zheng, Shichu Xiao, Zhaofan Xi. Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 2. 2019-02-28. PMID:29719102. |
risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. |
2019-02-28 |
2023-08-13 |
Not clear |
| Yongqiang Xiao, Yu Sun, Banghui Zhu, Kangan Wang, Pengfei Liang, Wenjun Liu, Jinfeng Fu, Shiqing Zheng, Shichu Xiao, Zhaofan Xi. Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 2. 2019-02-28. PMID:29719102. |
hypertrophic scar pain, pruritus, and paresthesia symptoms are major and particular concerns for burn patients. |
2019-02-28 |
2023-08-13 |
Not clear |
| Yongqiang Xiao, Yu Sun, Banghui Zhu, Kangan Wang, Pengfei Liang, Wenjun Liu, Jinfeng Fu, Shiqing Zheng, Shichu Xiao, Zhaofan Xi. Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 2. 2019-02-28. PMID:29719102. |
we reviewed the medical records of 129 postburn hypertrophy scar patients and divided them into two groups for each of three different symptoms based on the university of north carolina "4p" scar scale: patients with scar pain requiring occasional or continuous pharmacological intervention (hsc pain, n = 75) vs. patients without such scar pain (no hsc pain, n = 54); patients with scar pruritus requiring occasional or continuous pharmacological intervention (hsc pruritus, n = 63) vs. patients without such scar pruritus (no hsc pruritus, n = 66); patients with scar paresthesia that influenced the patients' daily activities (hsc paresthesia, n = 31) vs. patients without such scar paresthesia (no hsc paresthesia, n = 98). |
2019-02-28 |
2023-08-13 |
Not clear |
| Yongqiang Xiao, Yu Sun, Banghui Zhu, Kangan Wang, Pengfei Liang, Wenjun Liu, Jinfeng Fu, Shiqing Zheng, Shichu Xiao, Zhaofan Xi. Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 2. 2019-02-28. PMID:29719102. |
three multivariable logistic regression models were built, respectively, to identify the risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. |
2019-02-28 |
2023-08-13 |
Not clear |
| Yongqiang Xiao, Yu Sun, Banghui Zhu, Kangan Wang, Pengfei Liang, Wenjun Liu, Jinfeng Fu, Shiqing Zheng, Shichu Xiao, Zhaofan Xi. Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 2. 2019-02-28. PMID:29719102. |
multivariable analysis showed that hypertrophic burn scar pain development requiring pharmacological intervention was associated with old age (odds ratio [or] = 1.046; 95% confidence interval [ci], 1.011-1.082, p = 0.009), high body mass index (or = 1.242; 95%ci, 1.068-1.445, p = 0.005), 2-5-mm-thick postburn hypertrophic scars (or = 3.997; 95%ci, 1.523-10.487, p = 0.005), and 6-12-month postburn hypertrophic scars (or = 4.686; 95%ci, 1.318-16.653, p = 0.017). |
2019-02-28 |
2023-08-13 |
Not clear |
| Yongqiang Xiao, Yu Sun, Banghui Zhu, Kangan Wang, Pengfei Liang, Wenjun Liu, Jinfeng Fu, Shiqing Zheng, Shichu Xiao, Zhaofan Xi. Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 2. 2019-02-28. PMID:29719102. |
hypertrophic burn scar pruritus development requiring pharmacological intervention was associated with smoking (or = 3.239; 95%ci, 1.380-7.603; p = 0.007), having undergone surgical operation (or = 2.236; 95%ci, 1.001-4.998; p = 0.049), and firm scars (or = 3.317; 95%ci, 1.237-8.894; p = 0.017). |
2019-02-28 |
2023-08-13 |
Not clear |
| Yongqiang Xiao, Yu Sun, Banghui Zhu, Kangan Wang, Pengfei Liang, Wenjun Liu, Jinfeng Fu, Shiqing Zheng, Shichu Xiao, Zhaofan Xi. Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 26. issue 2. 2019-02-28. PMID:29719102. |
finally, hypertrophic burn scar paresthesia development which affected the patients' daily activities was associated with age (or = 1.038; 95%ci, 1.002-1.075; p = 0.040), fire burns (or = 0.041; 95%ci, 0.005-0.366; p = 0.004, other burns vs. flame burns), and banding and contracture scars (or = 4.705; 95%ci, 1.281-17.288, p = 0.020). |
2019-02-28 |
2023-08-13 |
Not clear |
| Abdulnaser Alkhalil, Bonnie C Carney, Taryn E Travis, Seid Muhie, Stacy-Ann Miller, Jessica C Ramella-Roman, Pejhman Ghassemi, Rasha Hammamieh, Marti Jett, Lauren T Moffatt, Jeffrey W Shup. Key Cell Functions are Modulated by Compression in an Animal Model of Hypertrophic Scar. Wounds : a compendium of clinical research and practice. vol 30. issue 12. 2019-02-28. PMID:30304713. |
key cell functions are modulated by compression in an animal model of hypertrophic scar. |
2019-02-28 |
2023-08-13 |
Not clear |
| Abdulnaser Alkhalil, Bonnie C Carney, Taryn E Travis, Seid Muhie, Stacy-Ann Miller, Jessica C Ramella-Roman, Pejhman Ghassemi, Rasha Hammamieh, Marti Jett, Lauren T Moffatt, Jeffrey W Shup. Key Cell Functions are Modulated by Compression in an Animal Model of Hypertrophic Scar. Wounds : a compendium of clinical research and practice. vol 30. issue 12. 2019-02-28. PMID:30304713. |
the value of compression studies and applications in hypertrophic scar (hts) treatment is often undermined due to the lack of ideal controls, patient compliance, and clear action mechanisms. |
2019-02-28 |
2023-08-13 |
Not clear |
| Yajuan Song, Zhou Yu, Baoqiang Song, Shuzhong Guo, Lei Lei, Xianjie Ma, Yingjun S. Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-02-27. PMID:30243085. |
usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis. |
2019-02-27 |
2023-08-13 |
human |
| Yajuan Song, Zhou Yu, Baoqiang Song, Shuzhong Guo, Lei Lei, Xianjie Ma, Yingjun S. Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-02-27. PMID:30243085. |
previous studies showed that angiogenesis plays an important role in the early phase of hypertrophic scarring and inhibition of angiogenesis has been reported as an effective strategy for anti-hypertrophic scar therapy. |
2019-02-27 |
2023-08-13 |
human |
| Yajuan Song, Zhou Yu, Baoqiang Song, Shuzhong Guo, Lei Lei, Xianjie Ma, Yingjun S. Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-02-27. PMID:30243085. |
to investigate the therapeutic effects of ua on hypertrophic scarring and to explore the possible mechanism involved, a rabbit ear hypertrophic scar model was established. |
2019-02-27 |
2023-08-13 |
human |
| Yajuan Song, Zhou Yu, Baoqiang Song, Shuzhong Guo, Lei Lei, Xianjie Ma, Yingjun S. Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-02-27. PMID:30243085. |
histological evaluation of hematoxylin and eosin staining indicated that ua significantly inhibited hypertrophic scar formation, with obvious reductions in scar height and coloration. |
2019-02-27 |
2023-08-13 |
human |
| Yajuan Song, Zhou Yu, Baoqiang Song, Shuzhong Guo, Lei Lei, Xianjie Ma, Yingjun S. Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-02-27. PMID:30243085. |
these results provide the first evidence of the therapeutic effectiveness of ua in hypertrophic scar formation in an animal model via a mechanism that involves suppression of scar angiogenesis. |
2019-02-27 |
2023-08-13 |
human |
| Seiji Komatsu, Akira Shinaoka, Yoshihiro Kimat. Modified Posterolateral Approach for Pterygium Colli. The Journal of craniofacial surgery. vol 30. issue 1. 2019-02-25. PMID:30444770. |
z-plasty was performed at the posterior midline of the neck to prevent hypertrophic scar formation. |
2019-02-25 |
2023-08-13 |
Not clear |
| Xiao Xu, Linying Lai, Xuyi Zhang, Jinhong Chen, Junnan Chen, Fei Wang, Jingchen Zheng, Minliang Che. Autologous chyle fat grafting for the treatment of hypertrophic scars and scar-related conditions. Stem cell research & therapy. vol 9. issue 1. 2019-01-28. PMID:29523181. |
in this study, we investigated the ability of autologous chyle fat injection to normalize the fibroblasts and collagen of scar tissue in 80 adult patients with hypertrophic scars resulting from severe burns received more than 1 year previously. |
2019-01-28 |
2023-08-13 |
Not clear |