| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingli Song, Bingyu Guo, Shudan Ma, Peng Chang, Kai Ta. Naringin suppresses the growth and motility of hypertrophic scar fibroblasts by inhibiting the kinase activity of Akt. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 105. 2018-11-02. PMID:30021366. |
naringin suppresses the growth and motility of hypertrophic scar fibroblasts by inhibiting the kinase activity of akt. |
2018-11-02 |
2023-08-13 |
human |
| Yingli Song, Bingyu Guo, Shudan Ma, Peng Chang, Kai Ta. Naringin suppresses the growth and motility of hypertrophic scar fibroblasts by inhibiting the kinase activity of Akt. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 105. 2018-11-02. PMID:30021366. |
hypertrophy is a very common pathologic phenomenon of scar hyperplasia after human skin injury and wound healing. |
2018-11-02 |
2023-08-13 |
human |
| Yingli Song, Bingyu Guo, Shudan Ma, Peng Chang, Kai Ta. Naringin suppresses the growth and motility of hypertrophic scar fibroblasts by inhibiting the kinase activity of Akt. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 105. 2018-11-02. PMID:30021366. |
we also found that naringin specifically inhibits the kinase activity of akt and the phosphorylation of akt in hypertrophic scar fibroblasts by kinase-glo, western blot and real-time pcr assays. |
2018-11-02 |
2023-08-13 |
human |
| Tiago Costa Bignoto, Dalmo Antônio Ribeiro Moreira, Ricardo Garbe Habib, Edileide de Barros Correia, Ricardo Carneiro Amarante, Tannas Jatene, Mario Barbosa Guedes Nunes, Tiago Senra, Luiz Eduardo Mastrocoll. Electrocardiography scar quantification correlates with scar size of hypertrophic cardiomyopathy seen by multidetector computed tomography. Clinical cardiology. vol 41. issue 6. 2018-10-23. PMID:29671882. |
electrocardiography scar quantification correlates with scar size of hypertrophic cardiomyopathy seen by multidetector computed tomography. |
2018-10-23 |
2023-08-13 |
Not clear |
| Xue Wu, Jun Li, Xuekang Yang, Xiaozhi Bai, Jihong Shi, Jianxin Gao, Yan Li, Shichao Han, Yijie Zhang, Fu Han, Yang Liu, Xiaoqiang Li, Kejia Wang, Julei Zhang, Zheng Wang, Ke Tao, Dahai H. miR-155 inhibits the formation of hypertrophic scar fibroblasts by targeting HIF-1α via PI3K/AKT pathway. Journal of molecular histology. vol 49. issue 4. 2018-10-22. PMID:29785488. |
mir-155 inhibits the formation of hypertrophic scar fibroblasts by targeting hif-1α via pi3k/akt pathway. |
2018-10-22 |
2023-08-13 |
rabbit |
| Xue Wu, Jun Li, Xuekang Yang, Xiaozhi Bai, Jihong Shi, Jianxin Gao, Yan Li, Shichao Han, Yijie Zhang, Fu Han, Yang Liu, Xiaoqiang Li, Kejia Wang, Julei Zhang, Zheng Wang, Ke Tao, Dahai H. miR-155 inhibits the formation of hypertrophic scar fibroblasts by targeting HIF-1α via PI3K/AKT pathway. Journal of molecular histology. vol 49. issue 4. 2018-10-22. PMID:29785488. |
hypertrophic scar (hs) is a serious skin fibrotic disease characterized by the excessive proliferation of fibroblasts and often considered as a kind of benign skin tumor. |
2018-10-22 |
2023-08-13 |
rabbit |
| Xue Wu, Jun Li, Xuekang Yang, Xiaozhi Bai, Jihong Shi, Jianxin Gao, Yan Li, Shichao Han, Yijie Zhang, Fu Han, Yang Liu, Xiaoqiang Li, Kejia Wang, Julei Zhang, Zheng Wang, Ke Tao, Dahai H. miR-155 inhibits the formation of hypertrophic scar fibroblasts by targeting HIF-1α via PI3K/AKT pathway. Journal of molecular histology. vol 49. issue 4. 2018-10-22. PMID:29785488. |
in view of the similarities of hypertrophic scar and tumor, it is predicted that mir-155 may be a novel therapeutic target in clinical trials. |
2018-10-22 |
2023-08-13 |
rabbit |
| Xue Wu, Jun Li, Xuekang Yang, Xiaozhi Bai, Jihong Shi, Jianxin Gao, Yan Li, Shichao Han, Yijie Zhang, Fu Han, Yang Liu, Xiaoqiang Li, Kejia Wang, Julei Zhang, Zheng Wang, Ke Tao, Dahai H. miR-155 inhibits the formation of hypertrophic scar fibroblasts by targeting HIF-1α via PI3K/AKT pathway. Journal of molecular histology. vol 49. issue 4. 2018-10-22. PMID:29785488. |
together, our results indicated that mir-155 was a critical regulator in the formation and development of hypertrophic scar and might be a potential molecular target for hypertrophic scar therapy. |
2018-10-22 |
2023-08-13 |
rabbit |
| Saurav Kumar, Sanjeev Harbansh Gupta, M Viswambaran, Arpreeta Sachdeva, B P Pand. Management of postburn perioral contracture using a customized static commissural splint and intralesional injections of triamcinolone. The Journal of prosthetic dentistry. vol 119. issue 3. 2018-10-22. PMID:28689910. |
overcoming these contractures to regain the size of the stoma requires restructuring of the hypertrophic scar using mechanical force and the biomodification of the tissues. |
2018-10-22 |
2023-08-13 |
Not clear |
| Tatiana V Boyko, Rakesh Bam, Dadi Jiang, Zhen Wang, Namrata Bhatia, Misha C Tran, Michael T Longaker, Albert C Koong, George P Yan. Inhibition of IRE1 results in decreased scar formation. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 25. issue 6. 2018-10-16. PMID:29316036. |
results were recapitulated in a hypertrophic scar mouse model. |
2018-10-16 |
2023-08-13 |
mouse |
| Jin-Wei Ai, Jiang-Tao Liu, Sheng-Duo Pei, Yu Liu, De-Sheng Li, Hong-Ming Lin, Bin Pe. The effectiveness of pressure therapy (15-25 mmHg) for hypertrophic burn scars: A systematic review and meta-analysis. Scientific reports. vol 7. 2018-10-15. PMID:28054644. |
although pressure therapy (pt) represents the standard care for prevention and treatment of hypertrophic scar (hs) from burns, its practice is largely based on empirical evidence and its effectiveness remains controversial. |
2018-10-15 |
2023-08-13 |
Not clear |
| Qian Zhang, Bingyu Guo, Qiang Hui, Peng Chang, Kai Ta. miR-137 Inhibits Proliferation and Metastasis of Hypertrophic Scar Fibroblasts via Targeting Pleiotrophin. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 49. issue 3. 2018-10-12. PMID:30184530. |
mir-137 inhibits proliferation and metastasis of hypertrophic scar fibroblasts via targeting pleiotrophin. |
2018-10-12 |
2023-08-13 |
Not clear |
| Recep Anlatici, Gökhan Özerdem, Sarp Demiralay, Ömer Refik Özerde. Face-neck lifting and ancillary procedures: A series of 203 cases. Medicine. vol 97. issue 39. 2018-10-12. PMID:30278509. |
complications, postoperative follow-up, esthetic outcomes, and contribution of the ancillary procedures were recorded.our esthetic face complication rates were comparable to those of previous studies and included chemosis, hematoma, cyst on the eyelid suture line, skin sloughing, scar abnormalities (hypertrophic scar and widespread scar), pseudoparalysis of the marginal mandibular branch, temporary hypoesthesia of the forehead, irregularity of the glabella after endoscopy, and asymmetry. |
2018-10-12 |
2023-08-13 |
Not clear |
| Chao-Kai Hsu, Hsi-Hui Lin, Hans I-Chen Harn, Michael W Hughes, Ming-Jer Tang, Chao-Chun Yan. Mechanical forces in skin disorders. Journal of dermatological science. vol 90. issue 3. 2018-10-01. PMID:29567352. |
keloid and hypertrophic scar, which is the result of over-production of collagen by fibroblasts during the wound healing, are associated with extrinsic tensile forces and changes of intrinsic mechanical properties of the cell. |
2018-10-01 |
2023-08-13 |
Not clear |
| Zheng Zhang, Yunsheng Chen, Heng Xu, Yan Wo, Zhen Zhang, Ying Liu, Weijie Su, Daxiang Cui, Yixin Zhan. 5-Aminolevulinic acid loaded ethosomal vesicles with high entrapment efficiency for in vitro topical transdermal delivery and photodynamic therapy of hypertrophic scars. Nanoscale. vol 8. issue 46. 2018-10-01. PMID:27830857. |
photodynamic therapy (pdt) with 5-aminolevulinic acid (ala) is an alternative therapy for hypertrophic scars (hs), which destroys human hypertrophic scar fibroblasts (hsf). |
2018-10-01 |
2023-08-13 |
human |
| Xiaoqian Zhou, Yidun Xie, Houan Xiao, Xudong Deng, Yu Wang, Liyuan Jiang, Chen Liu, Rui Zho. MicroRNA-519d inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting Sirtuin 7. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 100. 2018-10-01. PMID:29428666. |
microrna-519d inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting sirtuin 7. |
2018-10-01 |
2023-08-13 |
human |
| Xiaoqian Zhou, Yidun Xie, Houan Xiao, Xudong Deng, Yu Wang, Liyuan Jiang, Chen Liu, Rui Zho. MicroRNA-519d inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting Sirtuin 7. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 100. 2018-10-01. PMID:29428666. |
micrornas (mirnas) play critical roles in various pathological processes, including hypertrophic scar (hs) formation. |
2018-10-01 |
2023-08-13 |
human |
| J Füller, C C Müller-Goyman. Anti-proliferative and anti-migratory effects of hyperforin in 2D and 3D artificial constructs of human dermal fibroblasts - A new option for hypertrophic scar treatment? European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. vol 126. 2018-09-24. PMID:28288835. |
anti-proliferative and anti-migratory effects of hyperforin in 2d and 3d artificial constructs of human dermal fibroblasts - a new option for hypertrophic scar treatment? |
2018-09-24 |
2023-08-13 |
human |
| Britani N Blackstone, Jayne Y Kim, Kevin L McFarland, Chandan K Sen, Dorothy M Supp, J Kevin Bailey, Heather M Powel. Scar formation following excisional and burn injuries in a red Duroc pig model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 25. issue 4. 2018-09-18. PMID:28727221. |
compared with scars from dermatome wounds, the burn scar model described here demonstrates greater similarity to human hypertrophic scar. |
2018-09-18 |
2023-08-13 |
human |
| Britani N Blackstone, Jayne Y Kim, Kevin L McFarland, Chandan K Sen, Dorothy M Supp, J Kevin Bailey, Heather M Powel. Scar formation following excisional and burn injuries in a red Duroc pig model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. vol 25. issue 4. 2018-09-18. PMID:28727221. |
thus, this burn scar model may provide an improved platform for studying the pathophysiology of burn-related hypertrophic scarring, investigating current anti-scar therapies, and development of new strategies with greater clinical benefit. |
2018-09-18 |
2023-08-13 |
human |