| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Monica A Newman, Qendrim Zebeli, Eva Eberspächer, Dietmar Grüll, Timea Molnar, Barbara U Metzler-Zebel. Transglycosylated Starch Improves Insulin Response and Alters Lipid and Amino Acid Metabolome in a Growing Pig Model. Nutrients. vol 9. issue 3. 2017-09-14. PMID:28300770. |
this study investigated the effect of transglycosylated cornstarch (tgs) on blood glucose, insulin, and serum metabolome in the pre- and postprandial phase in growing pigs. |
2017-09-14 |
2023-08-13 |
Not clear |
| Monica A Newman, Qendrim Zebeli, Eva Eberspächer, Dietmar Grüll, Timea Molnar, Barbara U Metzler-Zebel. Transglycosylated Starch Improves Insulin Response and Alters Lipid and Amino Acid Metabolome in a Growing Pig Model. Nutrients. vol 9. issue 3. 2017-09-14. PMID:28300770. |
tgs-fed pigs had reduced postprandial insulin ( |
2017-09-14 |
2023-08-13 |
Not clear |
| Dane M Horton, David A Saint, Julie A Owens, Kathryn L Gatford, Karen L Kin. Use of the hyperinsulinemic euglycemic clamp to assess insulin sensitivity in guinea pigs: dose response, partitioned glucose metabolism, and species comparisons. American journal of physiology. Regulatory, integrative and comparative physiology. vol 313. issue 1. 2017-08-16. PMID:28438760. |
use of the hyperinsulinemic euglycemic clamp to assess insulin sensitivity in guinea pigs: dose response, partitioned glucose metabolism, and species comparisons. |
2017-08-16 |
2023-08-13 |
mouse |
| Adriana D Hernandez-García, Daniel A Columbus, Rodrigo Manjarín, Hanh V Nguyen, Agus Suryawan, Renán A Orellana, Teresa A Davi. Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia. American journal of physiology. Endocrinology and metabolism. vol 311. issue 4. 2017-06-23. PMID:27624100. |
to determine if supplemental leu can stimulate ps and reduce protein degradation (pd) signaling in neonatal muscle during endotoxemia, overnight-fasted neonatal pigs were infused for 8 h with lps or saline while plasma amino acids, glucose, and insulin were maintained at fasting levels during pancreatic-substrate clamps. |
2017-06-23 |
2023-08-13 |
Not clear |
| Y He, J Deen, G C Shurson, L Wang, C Chen, D H Keisler, Y Z L. Identifying factors contributing to slow growth in pigs. Journal of animal science. vol 94. issue 5. 2017-06-14. PMID:27285707. |
these results suggest that low concentrations of igf-1, insulin, leptin, and aa may contribute to or be associated with slow growth in pigs. |
2017-06-14 |
2023-08-13 |
Not clear |
| Apolline Salama, Mathilde Mosser, Xavier Lévêque, Andrea Perota, Jean-Paul Judor, Corentin Danna, Sylvie Pogu, Anne Mouré, Dominique Jégou, Nicolas Gaide, Jérôme Abadie, Olivier Gauthier, Jean-Paul Concordet, Stéphanie Le Bas-Bernardet, David Riochet, Ludmilla Le Berre, Jérémy Hervouet, David Minault, Pierre Weiss, Jérôme Guicheux, Sophie Brouard, Steffi Bosch, Irina Lagutina, Roberto Duchi, Giovanna Lazzari, Emanuele Cozzi, Gilles Blancho, Sophie Conchon, Cesare Galli, Jean-Paul Soulillou, Jean-Marie Bac. Neu5Gc and α1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs. Diabetes. vol 66. issue 4. 2017-06-13. PMID:28082457. |
neu5gc and α1-3 gal xenoantigen knockout does not affect glycemia homeostasis and insulin secretion in pigs. |
2017-06-13 |
2023-08-13 |
Not clear |
| Jun Wang, Meng Cao, Mei Yang, Yan Lin, Lianqiang Che, Zhengfeng Fang, Shengyu Xu, Bin Feng, Jian Li, De W. Intra-uterine undernutrition amplifies age-associated glucose intolerance in pigs via altered DNA methylation at muscle GLUT4 promoter. The British journal of nutrition. vol 116. issue 3. 2017-05-17. PMID:27265204. |
compared with con pigs, un pigs showed lower serum glucose concentrations at birth, but showed higher serum glucose and insulin concentrations as well as increased area under the blood glucose curve during intravenous glucose tolerance test at dpn189 (p<0·05). |
2017-05-17 |
2023-08-13 |
Not clear |
| David K C Cooper, Shinichi Matsumoto, Adrian Abalovich, Takeshi Itoh, Nizar I Mourad, Pierre R Gianello, Eckhard Wolf, Emanuele Cozz. Progress in Clinical Encapsulated Islet Xenotransplantation. Transplantation. vol 100. issue 11. 2017-05-17. PMID:27482959. |
the presentations focused on 5 major topics - (1) the results of 2 recent clinical trials of encapsulated pig islet transplantation, (2) the inflammatory response to encapsulated pig islets, (3) methods to improve the secretion of insulin by pig islets, (4) genetic modifications to the islet-source pigs aimed to protect the islets from the primate immune and/or inflammatory responses, and (5) regulatory aspects of clinical pig islet xenotransplantation. |
2017-05-17 |
2023-08-13 |
Not clear |
| David K C Cooper, Shinichi Matsumoto, Adrian Abalovich, Takeshi Itoh, Nizar I Mourad, Pierre R Gianello, Eckhard Wolf, Emanuele Cozz. Progress in Clinical Encapsulated Islet Xenotransplantation. Transplantation. vol 100. issue 11. 2017-05-17. PMID:27482959. |
further advances to improve efficacy may include (1) transplantation into a site other than the peritoneal cavity, which might result in better access to blood, oxygen, and nutrients; (2) the development of a more biocompatible capsule and/or the minimization of a foreign body reaction; (3) pig genetic modification to induce a greater secretion of insulin by the islets, and/or to reduce the immune response to islets released from damaged capsules; and (4) reduction of the inflammatory response to the capsules/islets by improvements in the structure of the capsules and/or in genetic engineering of the pigs and/or in some form of drug therapy. |
2017-05-17 |
2023-08-13 |
Not clear |
| Marta S Madeira, Virgínia M R Pires, Cristina M Alfaia, Paula A Lopes, Susana V Martins, Rui M A Pinto, José A M Prate. Restriction of dietary protein does not promote hepatic lipogenesis in lean or fatty pigs. The British journal of nutrition. vol 115. issue 8. 2017-05-05. PMID:26927728. |
the majority of plasma metabolites were affected by genotype, with lean pigs having higher contents of lipids, whereas fatty pigs presented higher insulin, leptin and urea levels. |
2017-05-05 |
2023-08-13 |
Not clear |
| A K Agyekum, E Kiarie, M C Walsh, C M Nyachot. Postprandial portal glucose and lactate fluxes, insulin production, and portal vein-drained viscera oxygen consumption in growing pigs fed a high-fiber diet supplemented with a multi-enzyme cocktail. Journal of animal science. vol 94. issue 9. 2017-04-24. PMID:27898890. |
postprandial portal glucose and lactate fluxes, insulin production, and portal vein-drained viscera oxygen consumption in growing pigs fed a high-fiber diet supplemented with a multi-enzyme cocktail. |
2017-04-24 |
2023-08-13 |
Not clear |
| A K Agyekum, E Kiarie, M C Walsh, C M Nyachot. Postprandial portal glucose and lactate fluxes, insulin production, and portal vein-drained viscera oxygen consumption in growing pigs fed a high-fiber diet supplemented with a multi-enzyme cocktail. Journal of animal science. vol 94. issue 9. 2017-04-24. PMID:27898890. |
therefore, this study investigated the effects of supplementing a high-fiber (hf) diet with a multi-enzyme cocktail (mc) on net glucose and lactate portal fluxes, insulin production, and o consumption by the portal-drained viscera (pdv) and whole animal in growing pigs. |
2017-04-24 |
2023-08-13 |
Not clear |
| A K Agyekum, E Kiarie, M C Walsh, C M Nyachot. Postprandial portal glucose and lactate fluxes, insulin production, and portal vein-drained viscera oxygen consumption in growing pigs fed a high-fiber diet supplemented with a multi-enzyme cocktail. Journal of animal science. vol 94. issue 9. 2017-04-24. PMID:27898890. |
pigs fed control had greater ( < 0.05) portal insulin and glucose fluxes, from 90 to 300 min and net glucose flux from 90 to 240 min postprandial. |
2017-04-24 |
2023-08-13 |
Not clear |
| G Daş, A Vernunft, S Görs, E Kanitz, J M Weitzel, K-P Brüssow, C C Metge. Effects of general anesthesia with ketamine in combination with the neuroleptic sedatives xylazine or azaperone on plasma metabolites and hormones in pigs. Journal of animal science. vol 94. issue 8. 2017-04-11. PMID:27695801. |
fasted pigs rotationally received either no drug, a single intravenous administration of a or x, or a or x combined with ketamine (ak or xk, respectively), and plasma concentrations of glucose, lactate, non-esterified fatty acids (nefa), triglycerides (tg), glucagon, insulin, and cortisol were determined for a 5-h period following administration. |
2017-04-11 |
2023-08-13 |
Not clear |
| Takayuki Tanaka, Minoru Fujita, Rita Bottino, Jon D Piganelli, Kevin McGrath, Jiang Li, Whayoung Lee, Hayato Iwase, Martin Wijkstrom, Suzanne Bertera, Cassandra Long, Douglas Landsittel, Ken Haruma, David K C Cooper, Hidetaka Har. Endoscopic biopsy of islet transplants in the gastric submucosal space provides evidence of islet graft rejection in diabetic pigs. Islets. vol 8. issue 1. 2016-12-22. PMID:26857703. |
the aim of this study was to determine whether endoscopic biopsy of islet allografts transplanted into the gsms in diabetic pigs can provide histopathological and immunohistochemical information that correlates with the clinical course (e.g.,, blood glucose level, insulin requirement). |
2016-12-22 |
2023-08-13 |
Not clear |
| Liudmyla Lozinska, Björn Weström, Olena Prykhodko, Andreas Lindqvist, Nils Wierup, Bo Ahrén, Katarzyna Szwiec, Stefan G Pierzynowsk. Decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs. Experimental physiology. vol 101. issue 1. 2016-10-19. PMID:26663041. |
decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs. |
2016-10-19 |
2023-08-13 |
Not clear |
| Liudmyla Lozinska, Björn Weström, Olena Prykhodko, Andreas Lindqvist, Nils Wierup, Bo Ahrén, Katarzyna Szwiec, Stefan G Pierzynowsk. Decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs. Experimental physiology. vol 101. issue 1. 2016-10-19. PMID:26663041. |
the epi pigs displayed increased fasting glucose concentrations compared with control animals (6.4 ± 0.4 versus 4.8 ± 0.1 mmol l(-1) , p < 0.0001) but unchanged insulin concentrations (2.4 ± 0.6 versus 2.1 ± 0.2 pmol l(-1) ). |
2016-10-19 |
2023-08-13 |
Not clear |
| Liudmyla Lozinska, Björn Weström, Olena Prykhodko, Andreas Lindqvist, Nils Wierup, Bo Ahrén, Katarzyna Szwiec, Stefan G Pierzynowsk. Decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs. Experimental physiology. vol 101. issue 1. 2016-10-19. PMID:26663041. |
during the ogtt and ivgtt, the epi pigs showed slower, impaired glucose utilization, with the disruption of a well-timed insulin response. |
2016-10-19 |
2023-08-13 |
Not clear |
| Liudmyla Lozinska, Björn Weström, Olena Prykhodko, Andreas Lindqvist, Nils Wierup, Bo Ahrén, Katarzyna Szwiec, Stefan G Pierzynowsk. Decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs. Experimental physiology. vol 101. issue 1. 2016-10-19. PMID:26663041. |
plasma c-peptide concentrations confirmed the delayed insulin response during the ivgtt in epi pigs. |
2016-10-19 |
2023-08-13 |
Not clear |
| Liudmyla Lozinska, Björn Weström, Olena Prykhodko, Andreas Lindqvist, Nils Wierup, Bo Ahrén, Katarzyna Szwiec, Stefan G Pierzynowsk. Decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs. Experimental physiology. vol 101. issue 1. 2016-10-19. PMID:26663041. |
oral pancreatic enzyme supplementation (pes) of epi pigs improved glucose clearance during ivgtt [auc(glucose) 1295 ± 70 mmol l(-1) × (120 min) in epi versus 1044 ± 32 mmol l(-1) × (120 min) in epi + pes, p < 0.0001] without reinforcing the release of insulin [auc(c-peptide) 14.4 ± 3.8 nmol l(-1) × (120 min) in epi versus 6.4 ± 1.3 nmol l(-1) × (120 min) in epi + pes, p < 0.002]. |
2016-10-19 |
2023-08-13 |
Not clear |