| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aliye Uc, Alicia K Olivier, Michelle A Griffin, David K Meyerholz, Jianrong Yao, Maisam Abu-El-Haija, Katherine M Buchanan, Oriana G Vanegas Calderón, Marwa Abu-El-Haija, Alejandro A Pezzulo, Leah R Reznikov, Mark J Hoegger, Michael V Rector, Lynda S Ostedgaard, Peter J Taft, Nick D Gansemer, Paula S Ludwig, Emma E Hornick, David A Stoltz, Katie L Ode, Michael J Welsh, John F Engelhardt, Andrew W Norri. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical science (London, England : 1979). vol 128. issue 2. 2014-11-25. PMID:25142104. |
glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. |
2014-11-25 |
2023-08-13 |
Not clear |
| Aliye Uc, Alicia K Olivier, Michelle A Griffin, David K Meyerholz, Jianrong Yao, Maisam Abu-El-Haija, Katherine M Buchanan, Oriana G Vanegas Calderón, Marwa Abu-El-Haija, Alejandro A Pezzulo, Leah R Reznikov, Mark J Hoegger, Michael V Rector, Lynda S Ostedgaard, Peter J Taft, Nick D Gansemer, Paula S Ludwig, Emma E Hornick, David A Stoltz, Katie L Ode, Michael J Welsh, John F Engelhardt, Andrew W Norri. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical science (London, England : 1979). vol 128. issue 2. 2014-11-25. PMID:25142104. |
in fetal pigs, pancreatic insulin and glucagon density was similar between cf and non-cf. |
2014-11-25 |
2023-08-13 |
Not clear |
| Aliye Uc, Alicia K Olivier, Michelle A Griffin, David K Meyerholz, Jianrong Yao, Maisam Abu-El-Haija, Katherine M Buchanan, Oriana G Vanegas Calderón, Marwa Abu-El-Haija, Alejandro A Pezzulo, Leah R Reznikov, Mark J Hoegger, Michael V Rector, Lynda S Ostedgaard, Peter J Taft, Nick D Gansemer, Paula S Ludwig, Emma E Hornick, David A Stoltz, Katie L Ode, Michael J Welsh, John F Engelhardt, Andrew W Norri. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical science (London, England : 1979). vol 128. issue 2. 2014-11-25. PMID:25142104. |
in newborn and older pigs, the insulin and glucagon density was unchanged between cf and non-cf per total pancreatic area, but increased per remnant lobular tissue in cf reflecting exocrine pancreatic loss. |
2014-11-25 |
2023-08-13 |
Not clear |
| Aliye Uc, Alicia K Olivier, Michelle A Griffin, David K Meyerholz, Jianrong Yao, Maisam Abu-El-Haija, Katherine M Buchanan, Oriana G Vanegas Calderón, Marwa Abu-El-Haija, Alejandro A Pezzulo, Leah R Reznikov, Mark J Hoegger, Michael V Rector, Lynda S Ostedgaard, Peter J Taft, Nick D Gansemer, Paula S Ludwig, Emma E Hornick, David A Stoltz, Katie L Ode, Michael J Welsh, John F Engelhardt, Andrew W Norri. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical science (London, England : 1979). vol 128. issue 2. 2014-11-25. PMID:25142104. |
second phase insulin secretion responsiveness was impaired in cf newborn pigs and significantly lower than that observed in non-cf newborns. |
2014-11-25 |
2023-08-13 |
Not clear |
| Aliye Uc, Alicia K Olivier, Michelle A Griffin, David K Meyerholz, Jianrong Yao, Maisam Abu-El-Haija, Katherine M Buchanan, Oriana G Vanegas Calderón, Marwa Abu-El-Haija, Alejandro A Pezzulo, Leah R Reznikov, Mark J Hoegger, Michael V Rector, Lynda S Ostedgaard, Peter J Taft, Nick D Gansemer, Paula S Ludwig, Emma E Hornick, David A Stoltz, Katie L Ode, Michael J Welsh, John F Engelhardt, Andrew W Norri. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical science (London, England : 1979). vol 128. issue 2. 2014-11-25. PMID:25142104. |
in summary, glycaemic abnormalities and insulin secretion defects were present in newborn cf pigs and spontaneous hyperglycaemia developed over time. |
2014-11-25 |
2023-08-13 |
Not clear |
| Jingbo Liu, Jian He, Yuekui Yang, Jie Yu, Xiangbing Mao, Bing Yu, Daiwen Che. Effects of intrauterine growth retardation and postnatal high-fat diet on hepatic inflammatory response in pigs. Archives of animal nutrition. vol 68. issue 2. 2014-11-17. PMID:24646150. |
the objective of this study was to investigate the glucose and insulin response of pigs with intrauterine growth retardation (iugr) to a high-fat (hf) feeding regimen and to observe the underlying toll-like receptor-4 (tlr4) signalling pathway. |
2014-11-17 |
2023-08-12 |
Not clear |
| Jingbo Liu, Jian He, Yuekui Yang, Jie Yu, Xiangbing Mao, Bing Yu, Daiwen Che. Effects of intrauterine growth retardation and postnatal high-fat diet on hepatic inflammatory response in pigs. Archives of animal nutrition. vol 68. issue 2. 2014-11-17. PMID:24646150. |
pigs fed hf diets had lower peak concentrations of glucose and insulin, which decreased more slowly than in pigs that received the control diets. |
2014-11-17 |
2023-08-12 |
Not clear |
| Jingbo Liu, Jian He, Yuekui Yang, Jie Yu, Xiangbing Mao, Bing Yu, Daiwen Che. Effects of intrauterine growth retardation and postnatal high-fat diet on hepatic inflammatory response in pigs. Archives of animal nutrition. vol 68. issue 2. 2014-11-17. PMID:24646150. |
in summary, hepatic tlr4 signalling pathway and inflammatory response induced by hf feeding played an important role in the aggravated development of insulin resistance in pigs. |
2014-11-17 |
2023-08-12 |
Not clear |
| Morgan Lamb, Kelly Laugenour, Ouwen Liang, Michael Alexander, Clarence E Foster, Jonathan R T Lake. In vitro maturation of viable islets from partially digested young pig pancreas. Cell transplantation. vol 23. issue 3. 2014-11-03. PMID:23394130. |
fetal and neonatal pigs yield insulin unresponsive islet-like cell clusters that become glucose-responsive after extended periods of time. |
2014-11-03 |
2023-08-12 |
Not clear |
| Agus Suryawan, Hanh V Nguyen, Rosemarie D Almonaci, Teresa A Davi. Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated. Amino acids. vol 45. issue 3. 2014-09-11. PMID:22643846. |
overnight fasted 6- and 26-day-old pigs were infused for 2 h with saline (control) or with insulin or amino acids to achieve fed levels while amino acids or insulin, respectively, as well as glucose were maintained at fasting levels. |
2014-09-11 |
2023-08-12 |
Not clear |
| Jun Zhou, Kaixun Huang, Xin Gen Le. Selenium and diabetes--evidence from animal studies. Free radical biology & medicine. vol 65. 2014-09-02. PMID:23867154. |
elevating dietary se intake (0.4 to 3.0mg/kg of diet) above the nutrient requirements, similar to overproduction of selenoproteins, led to insulin resistance and/or diabetes-like phenotypes in mice, rats, and pigs. |
2014-09-02 |
2023-08-12 |
mouse |
| J C Park, S C Kim, S D Lee, H C Jang, N K Kim, S H Lee, H J Jung, I C Kim, H H Seong, B H Cho. Effects of Dietary Fat Types on Growth Performance, Pork Quality, and Gene Expression in Growing-finishing Pigs. Asian-Australasian journal of animal sciences. vol 25. issue 12. 2014-07-22. PMID:25049542. |
the results of this study indicate that the type of dietary fat affects fatty acid composition and insulin signaling-related gene expression in the lm of pigs. |
2014-07-22 |
2023-08-13 |
Not clear |
| Marinus F W te Pas, Sietse-Jan Koopmans, Leo Kruijt, Mario P L Calus, Mari A Smit. Plasma proteome profiles associated with diet-induced metabolic syndrome and the early onset of metabolic syndrome in a pig model. PloS one. vol 8. issue 9. 2014-07-18. PMID:24086269. |
studying only the control pigs as a model for metabolic syndrome when fed the two diets showed correlations to the same parameters but now more focused on insulin, glucose and abdominal fat depot parameters. |
2014-07-18 |
2023-08-12 |
Not clear |
| V V Rushchak, M O Chashchy. [Insulin determination in pancreas of guinea pigs with metabolic syndrome]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 60. issue 2. 2014-07-17. PMID:25007520. |
[insulin determination in pancreas of guinea pigs with metabolic syndrome]. |
2014-07-17 |
2023-08-13 |
Not clear |
| V V Rushchak, M O Chashchy. [Insulin determination in pancreas of guinea pigs with metabolic syndrome]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 60. issue 2. 2014-07-17. PMID:25007520. |
in this work we determined the level of insulin in pancreatic cells of guinea pigs under normal conditions and during metabolic syndrome. |
2014-07-17 |
2023-08-13 |
Not clear |
| V V Rushchak, M O Chashchy. [Insulin determination in pancreas of guinea pigs with metabolic syndrome]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 60. issue 2. 2014-07-17. PMID:25007520. |
it was found that in guinea pigs metabolic syndrome modeling is accompanied by impaired insulin synthesis, degenerative changes in pancreatic tissue and increased blood glucose level. |
2014-07-17 |
2023-08-13 |
Not clear |
| Kirstine L Christensen, Mette S Hedemann, Helle N Lærke, Henry Jørgensen, Shivaprakash J Mutt, Karl-Heinz Herzig, Knud E Bach Knudse. Concentrated arabinoxylan but not concentrated β-glucan in wheat bread has similar effects on postprandial insulin as whole-grain rye in porto-arterial catheterized pigs. Journal of agricultural and food chemistry. vol 61. issue 32. 2014-07-07. PMID:23919413. |
concentrated arabinoxylan but not concentrated β-glucan in wheat bread has similar effects on postprandial insulin as whole-grain rye in porto-arterial catheterized pigs. |
2014-07-07 |
2023-08-12 |
Not clear |
| Kirstine L Christensen, Mette S Hedemann, Helle N Lærke, Henry Jørgensen, Shivaprakash J Mutt, Karl-Heinz Herzig, Knud E Bach Knudse. Concentrated arabinoxylan but not concentrated β-glucan in wheat bread has similar effects on postprandial insulin as whole-grain rye in porto-arterial catheterized pigs. Journal of agricultural and food chemistry. vol 61. issue 32. 2014-07-07. PMID:23919413. |
glucose absorption was reduced in pigs fed the ax bread at 60 min postprandial (3.1 mmol/min for ax compared to 9.4 mmol/min for wf, p = 0.02) and insulin secretion was lowered at 30 min postprandial for ax and gr (74.4 and 129 pmol/min for ax and gr, respectively, compared to 738 pmol/min for wf, p < 0.04). |
2014-07-07 |
2023-08-12 |
Not clear |
| Kimberly D Fisher, Tracy L Scheffler, Steven C Kasten, Brad M Reinholt, Gregory R van Eyk, Jeffery Escobar, Jason M Scheffler, David E Gerrar. Energy dense, protein restricted diet increases adiposity and perturbs metabolism in young, genetically lean pigs. PloS one. vol 8. issue 8. 2014-06-15. PMID:23991090. |
during ogtt, glucose area under the curve (auc) was higher and insulin auc was lower in hed pigs compared to controls (p = 0.001). |
2014-06-15 |
2023-08-12 |
Not clear |
| Andreas Lindqvist, Peter Spégel, Mikael Ekelund, Eliana Garcia Vaz, Stefan Pierzynowski, Maria F Gomez, Hindrik Mulder, Jan Hedenbro, Leif Groop, Nils Wieru. Gastric bypass improves β-cell function and increases β-cell mass in a porcine model. Diabetes. vol 63. issue 5. 2014-06-10. PMID:24487021. |
pancreatic expression of insulin and glucagon was elevated, and cells expressing the glucagon-like peptide 1 receptor were more abundant in rygb pigs. |
2014-06-10 |
2023-08-12 |
human |