| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Le Naou, N Le Floc'h, I Louveau, H Gilbert, F Gondre. Metabolic changes and tissue responses to selection on residual feed intake in growing pigs. Journal of animal science. vol 90. issue 13. 2013-07-25. PMID:22871936. |
plasma insulin was conversely greater (p = 0.049) in rfi(+) pigs at this stage. |
2013-07-25 |
2023-08-12 |
Not clear |
| Simone Renner, Christina Braun-Reichhart, Andreas Blutke, Nadja Herbach, Daniela Emrich, Elisabeth Streckel, Annegret Wünsch, Barbara Kessler, Mayuko Kurome, Andrea Bähr, Nikolai Klymiuk, Stefan Krebs, Oliver Puk, Hiroshi Nagashima, Jochen Graw, Helmut Blum, Ruediger Wanke, Eckhard Wol. Permanent neonatal diabetes in INS(C94Y) transgenic pigs. Diabetes. vol 62. issue 5. 2013-06-28. PMID:23274907. |
at 4.5 months, ins(c94y) transgenic pigs exhibited 41% reduced body weight, 72% decreased β-cell mass (-53% relative to body weight), and 60% lower fasting insulin levels compared with littermate controls. |
2013-06-28 |
2023-08-12 |
mouse |
| Simone Renner, Christina Braun-Reichhart, Andreas Blutke, Nadja Herbach, Daniela Emrich, Elisabeth Streckel, Annegret Wünsch, Barbara Kessler, Mayuko Kurome, Andrea Bähr, Nikolai Klymiuk, Stefan Krebs, Oliver Puk, Hiroshi Nagashima, Jochen Graw, Helmut Blum, Ruediger Wanke, Eckhard Wol. Permanent neonatal diabetes in INS(C94Y) transgenic pigs. Diabetes. vol 62. issue 5. 2013-06-28. PMID:23274907. |
β-cells of ins(c94y) transgenic pigs showed a marked reduction of insulin secretory granules and severe dilation of the endoplasmic reticulum. |
2013-06-28 |
2023-08-12 |
mouse |
| Bie Tan, Xinguo Li, Guoyao Wu, Xiangfeng Kong, Zhiqiang Liu, Tiejun Li, Yulong Yi. Dynamic changes in blood flow and oxygen consumption in the portal-drained viscera of growing pigs receiving acute administration of (L)-arginine. Amino acids. vol 43. issue 6. 2013-05-16. PMID:22660901. |
plasma concentrations of insulin and glucagon at the infusion times of 30-90 min were higher and of free fatty acids at the infusion times of 60-120 min were lower than those for the control pigs (p < 0.05). |
2013-05-16 |
2023-08-12 |
human |
| Barbara Stoll, Patrycja Jolanta Puiman, Liwei Cui, Xiaoyan Chang, Nancy Marie Benight, Caroline Bauchart-Thevret, Bolette Hartmann, Jens Juul Holst, Douglas Guy Burri. Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs. JPEN. Journal of parenteral and enteral nutrition. vol 36. issue 5. 2013-01-03. PMID:22549765. |
we previously showed that parenteral nutrition (pn) compared with formula feeding results in hepatic insulin resistance and steatosis in neonatal pigs. |
2013-01-03 |
2023-08-12 |
Not clear |
| I Fernández-Fígares, M Lachica, A Martín, R Nieto, L González-Valero, J M Rodríguez-López, J F Aguiler. Impact of dietary betaine and conjugated linoleic acid on insulin sensitivity, protein and fat metabolism of obese pigs. Animal : an international journal of animal bioscience. vol 6. issue 7. 2013-01-02. PMID:23031465. |
impact of dietary betaine and conjugated linoleic acid on insulin sensitivity, protein and fat metabolism of obese pigs. |
2013-01-02 |
2023-08-12 |
Not clear |
| I Fernández-Fígares, M Lachica, A Martín, R Nieto, L González-Valero, J M Rodríguez-López, J F Aguiler. Impact of dietary betaine and conjugated linoleic acid on insulin sensitivity, protein and fat metabolism of obese pigs. Animal : an international journal of animal bioscience. vol 6. issue 7. 2013-01-02. PMID:23031465. |
although serum insulin increased in cla, and especially in betaine + cla pigs (28% and 83%; p = 0.0001), indices of insulin resistance were unaffected. |
2013-01-02 |
2023-08-12 |
Not clear |
| Antonio Pinto, Darren T Juniper, Mert Sanil, Linda Morgan, Lynne Clark, Helmut Sies, Margaret P Rayman, Holger Steinbrenne. Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs. Journal of inorganic biochemistry. vol 114. 2012-12-07. PMID:22694857. |
after 16 weeks of intervention, fasting plasma insulin and cholesterol levels were non-significantly increased in the high-se pigs, whereas fasting glucose concentrations did not differ between the two groups. |
2012-12-07 |
2023-08-12 |
Not clear |
| J Boubaker, D Val-Laillet, S Guérin, C-H Malber. Brain processing of duodenal and portal glucose sensing. Journal of neuroendocrinology. vol 24. issue 8. 2012-11-05. PMID:22487360. |
the present study aimed to compare the respective influence of these sensing pathways on the eating patterns; plasma concentrations of glucose, insulin and glucagon-like peptide-1 (glp-1); and brain activity in juvenile pigs. |
2012-11-05 |
2023-08-12 |
Not clear |
| D Wray-Cahen, F R Dunshea, R D Boyd, A W Bell, D E Bauma. Porcine somatotropin alters insulin response in growing pigs by reducing insulin sensitivity rather than changing responsiveness. Domestic animal endocrinology. vol 43. issue 1. 2012-10-17. PMID:22425435. |
porcine somatotropin alters insulin response in growing pigs by reducing insulin sensitivity rather than changing responsiveness. |
2012-10-17 |
2023-08-12 |
Not clear |
| D Wray-Cahen, F R Dunshea, R D Boyd, A W Bell, D E Bauma. Porcine somatotropin alters insulin response in growing pigs by reducing insulin sensitivity rather than changing responsiveness. Domestic animal endocrinology. vol 43. issue 1. 2012-10-17. PMID:22425435. |
exogenous porcine somatotropin (pst) treatment consistently improves growth performance and reduces fat deposition in pigs, and it is hypothesized that one component of the mechanism is through altering the sensitivity and/or responsiveness to insulin. |
2012-10-17 |
2023-08-12 |
Not clear |
| Priya S Mir, Mao L He, Gregory Travis, Toby Entz, Tim McAllister, Sigrid Marchand, Al Schaefer, Jon Meadus, Pierre Lepage, Erasmus Okine, Michael V Dodso. Periodic 48 h feed withdrawal improves glucose tolerance in growing pigs by enhancing adipogenesis and lipogenesis. Nutrition & metabolism. vol 9. issue 1. 2012-10-02. PMID:22321818. |
thus, using pigs as the experimental model, the hypothesis that fw regimens influence glucose tolerance by influencing fat cell function was evaluated with the objective of determining the effect of a single (fwx1; at age of 19 wk for 48 h) or periodic, multiple (fwx4; 24 h fw at 7 and 11 wk of age and 48 h fw at 15 and 19 wk of age) fw on auc of glucose and insulin during the gtt relative to pigs that did not experience fw (control). |
2012-10-02 |
2023-08-12 |
rat |
| Anthony P Kett, Christine M Bruen, Fiona O'Halloran, Valérie Chaurin, Peadar G Lawlor, James A O'Mahony, Linda Giblin, Mark A Fenelo. The effect of α- or β-casein addition to waxy maize starch on postprandial levels of glucose, insulin, and incretin hormones in pigs as a model for humans. Food & nutrition research. vol 56. 2012-08-23. PMID:22509144. |
the effect of α- or β-casein addition to waxy maize starch on postprandial levels of glucose, insulin, and incretin hormones in pigs as a model for humans. |
2012-08-23 |
2023-08-12 |
human |
| Nikolai Klymiuk, Lelia van Buerck, Andrea Bähr, Monika Offers, Barbara Kessler, Annegret Wuensch, Mayuko Kurome, Michael Thormann, Katharina Lochner, Hiroshi Nagashima, Nadja Herbach, Rüdiger Wanke, Jochen Seissler, Eckhard Wol. Xenografted islet cell clusters from INSLEA29Y transgenic pigs rescue diabetes and prevent immune rejection in humanized mice. Diabetes. vol 61. issue 6. 2012-07-25. PMID:22522620. |
as potential donor animals, we generated transgenic pigs expressing lea29y, a high-affinity variant of the t-cell costimulation inhibitor ctla-4ig, under the control of the porcine insulin gene promoter. |
2012-07-25 |
2023-08-12 |
mouse |
| Qinghua He, Pingping Ren, Xiangfeng Kong, Yongning Wu, Guoyao Wu, Peng Li, Fuhua Hao, Huiru Tang, François Blachier, Yulong Yi. Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach. The Journal of nutritional biochemistry. vol 23. issue 2. 2012-05-16. PMID:21429726. |
serum concentrations of insulin and glucagon were higher (p<.02) in obese than in lean pigs. |
2012-05-16 |
2023-08-12 |
Not clear |
| Matthew A Sabin, Steven W Yau, Vincenzo C Russo, Iain J Clarke, Frank R Dunshea, Jillian Chau, Maree Cox, George A Werthe. Dietary monounsaturated fat in early life regulates IGFBP2: implications for fat mass accretion and insulin sensitivity. Obesity (Silver Spring, Md.). vol 19. issue 12. 2012-05-09. PMID:21436793. |
the aim of this study was to investigate effects of dietary supplementation with fat or sugar on body composition (bc) and insulin sensitivity (is) in maturing pigs. |
2012-05-09 |
2023-08-12 |
Not clear |
| Matthew A Sabin, Steven W Yau, Vincenzo C Russo, Iain J Clarke, Frank R Dunshea, Jillian Chau, Maree Cox, George A Werthe. Dietary monounsaturated fat in early life regulates IGFBP2: implications for fat mass accretion and insulin sensitivity. Obesity (Silver Spring, Md.). vol 19. issue 12. 2012-05-09. PMID:21436793. |
whole-body is was decreased in those fed fat (p = 0.04), with fasting insulin increased in muf-fed pigs (p = 0.03). |
2012-05-09 |
2023-08-12 |
Not clear |
| Matthew A Sabin, Steven W Yau, Vincenzo C Russo, Iain J Clarke, Frank R Dunshea, Jillian Chau, Maree Cox, George A Werthe. Dietary monounsaturated fat in early life regulates IGFBP2: implications for fat mass accretion and insulin sensitivity. Obesity (Silver Spring, Md.). vol 19. issue 12. 2012-05-09. PMID:21436793. |
sm igfbp2 mrna was increased in muf-fed pigs (p = 0.009) and, in all animals, sm igfbp2 mrna correlated with total (p = 0.007) and visceral (p = 0.001) fat, fasting insulin (r = 0.321; p = 0.03) and change in nefa concentrations (r = 0.285; p = 0.047). |
2012-05-09 |
2023-08-12 |
Not clear |
| Matthew A Sabin, Steven W Yau, Vincenzo C Russo, Iain J Clarke, Frank R Dunshea, Jillian Chau, Maree Cox, George A Werthe. Dietary monounsaturated fat in early life regulates IGFBP2: implications for fat mass accretion and insulin sensitivity. Obesity (Silver Spring, Md.). vol 19. issue 12. 2012-05-09. PMID:21436793. |
in conclusion, diets high in fat, but not sugar, promote visceral adiposity and insulin resistance in maturing pigs, with evidence that fatty acids have direct and indirect effects on igfbp2 mrna expression in muscle. |
2012-05-09 |
2023-08-12 |
Not clear |
| Marco Marigliano, Suzanne Bertera, Maria Grupillo, Massimo Trucco, Rita Bottin. Pig-to-nonhuman primates pancreatic islet xenotransplantation: an overview. Current diabetes reports. vol 11. issue 5. 2012-04-24. PMID:21805400. |
particularly promising results in the achievement of prolonged insulin independence were obtained with newly developed, genetically modified pigs islets able to produce immunoregulatory products, using different implantation sites, and new immunotherapeutic strategies. |
2012-04-24 |
2023-08-12 |
Not clear |