| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian Qiu, Martha A Bosch, Cecilia Meza, Uyen-Vy Navarro, Casey C Nestor, Edward J Wagner, Oline K Rønnekleiv, Martin J Kell. Estradiol Protects Proopiomelanocortin Neurons Against Insulin Resistance. Endocrinology. vol 159. issue 2. 2018-05-15. PMID:29165691. |
as proof of principle, insulin [intracerebroventricular injection into the third ventricle (icv)] decreased food intake and increased metabolism in female but not male guinea pigs fed a high-fat diet. |
2018-05-15 |
2023-08-13 |
mouse |
| Jian Qiu, Martha A Bosch, Cecilia Meza, Uyen-Vy Navarro, Casey C Nestor, Edward J Wagner, Oline K Rønnekleiv, Martin J Kell. Estradiol Protects Proopiomelanocortin Neurons Against Insulin Resistance. Endocrinology. vol 159. issue 2. 2018-05-15. PMID:29165691. |
the uncoupling of the insulin receptor from its downstream effector system was corroborated by the reduced expression of phosphorylated protein kinase b in the arcuate nucleus of male but not female guinea pigs following insulin. |
2018-05-15 |
2023-08-13 |
mouse |
| Venkata Charepalli, Lavanya Reddivari, Sridhar Radhakrishnan, Elisabeth Eriksson, Xia Xiao, Sung Woo Kim, Frank Shen, Matam Vijay-Kumar, Qunhua Li, Vadiraja B Bhat, Rob Knight, Jairam K P Vanamal. Pigs, Unlike Mice, Have Two Distinct Colonic Stem Cell Populations Similar to Humans That Respond to High-Calorie Diet prior to Insulin Resistance. Cancer prevention research (Philadelphia, Pa.). vol 10. issue 8. 2018-04-26. PMID:28576788. |
pigs, unlike mice, have two distinct colonic stem cell populations similar to humans that respond to high-calorie diet prior to insulin resistance. |
2018-04-26 |
2023-08-13 |
mouse |
| Chunbo Cai, Lili Qian, Shengwang Jiang, Youde Sun, Qingqing Wang, Dezun Ma, Gaojun Xiao, Biao Li, Shanshan Xie, Ting Gao, Yaoxing Chen, Jie Liu, Xiaorong An, Wentao Cui, Kui L. Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs. Oncotarget. vol 8. issue 21. 2018-03-13. PMID:28432282. |
loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in meishan pigs. |
2018-03-13 |
2023-08-13 |
mouse |
| Chunbo Cai, Lili Qian, Shengwang Jiang, Youde Sun, Qingqing Wang, Dezun Ma, Gaojun Xiao, Biao Li, Shanshan Xie, Ting Gao, Yaoxing Chen, Jie Liu, Xiaorong An, Wentao Cui, Kui L. Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs. Oncotarget. vol 8. issue 21. 2018-03-13. PMID:28432282. |
in this study, we investigated if the inhibition of porcine myostatin has any effect on fat deposition and insulin sensitivity using genetically engineered meishan pigs containing a myostatin loss-of-function mutation (mstn -/- ). |
2018-03-13 |
2023-08-13 |
mouse |
| Chunbo Cai, Lili Qian, Shengwang Jiang, Youde Sun, Qingqing Wang, Dezun Ma, Gaojun Xiao, Biao Li, Shanshan Xie, Ting Gao, Yaoxing Chen, Jie Liu, Xiaorong An, Wentao Cui, Kui L. Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs. Oncotarget. vol 8. issue 21. 2018-03-13. PMID:28432282. |
additionally, the serum insulin level decreased and the insulin sensitivity increased significantly in mstn -/- pigs. |
2018-03-13 |
2023-08-13 |
mouse |
| Chunbo Cai, Lili Qian, Shengwang Jiang, Youde Sun, Qingqing Wang, Dezun Ma, Gaojun Xiao, Biao Li, Shanshan Xie, Ting Gao, Yaoxing Chen, Jie Liu, Xiaorong An, Wentao Cui, Kui L. Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs. Oncotarget. vol 8. issue 21. 2018-03-13. PMID:28432282. |
moreover, we found a significant increase in levels of insulin receptor and insulin receptor substrate proteins in skeletal muscle of mstn -/- pigs, which then activating the insulin signaling pathway. |
2018-03-13 |
2023-08-13 |
mouse |
| Yaqian Liu, Jifang Yuan, Lei Xiang, Yuqiong Zhao, Miaomiao Niu, Xin Dai, Hua Che. A high sucrose and high fat diet induced the development of insulin resistance in the skeletal muscle of Bama miniature pigs through the Akt/GLUT4 pathway. Experimental animals. vol 66. issue 4. 2018-02-22. PMID:28674285. |
a high sucrose and high fat diet induced the development of insulin resistance in the skeletal muscle of bama miniature pigs through the akt/glut4 pathway. |
2018-02-22 |
2023-08-13 |
Not clear |
| Yaqian Liu, Jifang Yuan, Lei Xiang, Yuqiong Zhao, Miaomiao Niu, Xin Dai, Hua Che. A high sucrose and high fat diet induced the development of insulin resistance in the skeletal muscle of Bama miniature pigs through the Akt/GLUT4 pathway. Experimental animals. vol 66. issue 4. 2018-02-22. PMID:28674285. |
this study aimed to investigate the molecular mechanisms by which the hshf diet impairs insulin sensitivity in bama miniature pigs (sus scrofa domesticus). |
2018-02-22 |
2023-08-13 |
Not clear |
| Yaqian Liu, Jifang Yuan, Lei Xiang, Yuqiong Zhao, Miaomiao Niu, Xin Dai, Hua Che. A high sucrose and high fat diet induced the development of insulin resistance in the skeletal muscle of Bama miniature pigs through the Akt/GLUT4 pathway. Experimental animals. vol 66. issue 4. 2018-02-22. PMID:28674285. |
this study demonstrates that a 6-month hshf diet caused ir, decreased insulin sensitivity, and reduced the expression of p-akt s473 and glut4 in the skeletal muscle of bama miniature pigs. |
2018-02-22 |
2023-08-13 |
Not clear |
| Jie Zhang, Jie Chai, Zonggang Luo, Hang He, Lei Chen, Xueqin Liu, Qinfei Zho. Meat and nutritional quality comparison of purebred and crossbred pigs. Animal science journal = Nihon chikusan Gakkaiho. vol 89. issue 1. 2018-02-22. PMID:28856768. |
the results showed that meat from the ly and dly crosses had lower values for lightness l24h∗, shear force and epinephrine and higher values for drip loss, c18:1, insulin, glucagon and monounsaturated fatty acids than d, l and y pigs. |
2018-02-22 |
2023-08-13 |
Not clear |
| M Saqui-Salces, Z Luo, P E Urriola, B J Kerr, G C Shurso. Effect of dietary fiber and diet particle size on nutrient digestibility and gastrointestinal secretory function in growing pigs. Journal of animal science. vol 95. issue 6. 2017-12-19. PMID:28727063. |
pigs were fed finely (374 ± 29 µm) or coarsely (631 ± 35 µm) ground corn-soybean meal (csb), csb + 35% corn dried distillers' grains with solubles (ddgs), and csb with 21% soybean hulls (sbh) diets for 49 d. diet composition, nutrient digestibility, along with fasting plasma concentrations of gastrin, insulin, glucagon-like peptide-1 (glp-1), glucose-dependent insulinotropic peptide (gip), tba, cholesterol, and glucose were measured. |
2017-12-19 |
2023-08-13 |
Not clear |
| M Saqui-Salces, Z Luo, P E Urriola, B J Kerr, G C Shurso. Effect of dietary fiber and diet particle size on nutrient digestibility and gastrointestinal secretory function in growing pigs. Journal of animal science. vol 95. issue 6. 2017-12-19. PMID:28727063. |
insulin concentration of pigs fed csb was greater ( < 0.01) in pigs fed fine compared with coarse ddgs, and was greater ( < 0.05) in coarse compared with fine sbh diets. |
2017-12-19 |
2023-08-13 |
Not clear |
| Andreas Lindqvist, Mikael Ekelund, Stefan Pierzynowski, Leif Groop, Jan Hedenbro, Nils Wieru. Gastric bypass in the pig increases GIP levels and decreases active GLP-1 levels. Peptides. vol 90. 2017-11-29. PMID:28242256. |
early insulin release (eir) was enhanced approximately 3.5-fold in the rygb pigs (p<0.01). |
2017-11-29 |
2023-08-13 |
human |
| Andreas Lindqvist, Mikael Ekelund, Stefan Pierzynowski, Leif Groop, Jan Hedenbro, Nils Wieru. Gastric bypass in the pig increases GIP levels and decreases active GLP-1 levels. Peptides. vol 90. 2017-11-29. PMID:28242256. |
in conclusion, rygb in lean pigs increases the response of gip, total glp-1, and insulin, but reduces levels of active glp-1 in response to an oral glucose load. |
2017-11-29 |
2023-08-13 |
human |
| Adriana Hernandez-García, Rodrigo Manjarín, Agus Suryawan, Hanh V Nguyen, Teresa A Davis, Renán A Orellan. Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia. Pediatric research. vol 80. issue 3. 2017-11-16. PMID:27064245. |
amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia. |
2017-11-16 |
2023-08-13 |
Not clear |
| Rodrigo Manjarín, Agus Suryawan, Sue J Koo, Fiona A Wilson, Hanh V Nguyen, Teresa A Davis, Renán A Orellan. Insulin modulates energy and substrate sensing and protein catabolism induced by chronic peritonitis in skeletal muscle of neonatal pigs. Pediatric research. vol 80. issue 5. 2017-11-16. PMID:27508897. |
insulin modulates energy and substrate sensing and protein catabolism induced by chronic peritonitis in skeletal muscle of neonatal pigs. |
2017-11-16 |
2023-08-13 |
Not clear |
| Anneli Rydén, Görel Nyman, Lovisa Nalin, Susanne Andreasson, Irina Velikyan, Olle Korsgren, Olof Eriksson, Marianne Jensen-Waer. Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs. Nuclear medicine and biology. vol 43. issue 7. 2017-11-06. PMID:27179248. |
cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled exendin-4 in pigs. |
2017-11-06 |
2023-08-13 |
monkey |
| Anneli Rydén, Görel Nyman, Lovisa Nalin, Susanne Andreasson, Irina Velikyan, Olle Korsgren, Olof Eriksson, Marianne Jensen-Waer. Cardiovascular side-effects and insulin secretion after intravenous administration of radiolabeled Exendin-4 in pigs. Nuclear medicine and biology. vol 43. issue 7. 2017-11-06. PMID:27179248. |
the iv effect of the tracer on insulin secretion is also investigated in pigs. |
2017-11-06 |
2023-08-13 |
monkey |
| Annie E Newell-Fugate, Katherine Lenz, Cassandra Skenandore, Romana A Nowak, Bryan A White, Andrea Braundmeier-Flemin. Effects of coconut oil on glycemia, inflammation, and urogenital microbial parameters in female Ossabaw mini-pigs. PloS one. vol 12. issue 7. 2017-09-20. PMID:28704429. |
obese pigs had decreased cytokine levels (il-1β, tnf-α, il-4, il-10), arachidonic acid and plasma insulin, but increased levels of vaccenic acid. |
2017-09-20 |
2023-08-13 |
Not clear |