| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Praneeth Namburi, Ream Al-Hasani, Gwendolyn G Calhoon, Michael R Bruchas, Kay M Ty. Architectural Representation of Valence in the Limbic System. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 7. 2018-01-02. PMID:26647973. |
until recently, the result of this work has been the identification of specific brain regions, such as the basolateral amygdala (bla) and nucleus accumbens (nac), as important to valence encoding. |
2018-01-02 |
2023-08-13 |
Not clear |
| Kequan Fu, Yoshiaki Miyamoto, Kazuyuki Sumi, Eriko Saika, Shin-Ichi Muramatsu, Kyosuke Uno, Atsumi Nitt. Overexpression of transmembrane protein 168 in the mouse nucleus accumbens induces anxiety and sensorimotor gating deficit. PloS one. vol 12. issue 12. 2017-12-29. PMID:29211814. |
it is reported that tmem168 controls methamphetamine (meth) dependence in the nucleus accumbens (nac) of mice. |
2017-12-29 |
2023-08-13 |
mouse |
| Malavika Murugan, Hee Jae Jang, Michelle Park, Ellia M Miller, Julia Cox, Joshua P Taliaferro, Nathan F Parker, Varun Bhave, Hong Hur, Yupu Liang, Alexander R Nectow, Jonathan W Pillow, Ilana B Witte. Combined Social and Spatial Coding in a Descending Projection from the Prefrontal Cortex. Cell. vol 171. issue 7. 2017-12-28. PMID:29224779. |
we found that pl contains anatomically and molecularly distinct subpopulations that target three downstream regions that have been implicated in social behavior: the nucleus accumbens (nac), amygdala, and ventral tegmental area. |
2017-12-28 |
2023-08-13 |
Not clear |
| Zuleide M Ignácio, Gislaine Z Réus, Helena M Abelaira, Amanda L Maciel, Airam B de Moura, Danyela Matos, Júlia P Demo, Júlia B I da Silva, Fernanda F Gava, Samira S Valvassori, André F Carvalho, João Queved. Quetiapine treatment reverses depressive-like behavior and reduces DNA methyltransferase activity induced by maternal deprivation. Behavioural brain research. vol 320. 2017-12-27. PMID:27913254. |
this study aimed to analyze the effect of chronic treatment with quetiapine (20mg/kg) on depressive-like behavior of rats submitted to maternal deprivation (md), as well as the activity of histone acetylation by the enzymes histone acetyl transferases (hat) and deacetylases (hdac) and dna methylation, through dna methyltransferase enzyme (dnmt) in the prefrontal cortex (pfc), nucleus accumbens (nac) and hippocampus. |
2017-12-27 |
2023-08-13 |
rat |
| Alqassem Y Hakami, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of orally administered Augmentin on glutamate transporter 1, cystine-glutamate exchanger expression and ethanol intake in alcohol-preferring rats. Behavioural brain research. vol 320. 2017-12-27. PMID:27993695. |
importantly, the attenuation in ethanol consumption was associated with a significant upregulation of glt-1 and xct expression in nucleus accumbens (nac) and prefrontal cortex (pfc). |
2017-12-27 |
2023-08-13 |
human |
| Alyssa L Peechatka, Amy C Jane. Association Between Reward Reactivity and Drug Use Severity is Substance Dependent: Preliminary Evidence From the Human Connectome Project. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 19. issue 6. 2017-12-27. PMID:28486710. |
blunted nucleus accumbens (nac) reactivity to reward is common across drug users. |
2017-12-27 |
2023-08-13 |
human |
| William A Carlezon, Andrew D Krysta. Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials. Depression and anxiety. vol 33. issue 10. 2017-12-26. PMID:27699938. |
the discovery of their potentially therapeutic effects evolved from preclinical research designed to characterize the molecular mechanisms by which experience causes neuroadaptations in the nucleus accumbens (nac), a key element of brain reward circuitry. |
2017-12-26 |
2023-08-13 |
Not clear |
| Francesca Felicia Caputi, Martina Palmisano, Lucia Carboni, Sanzio Candeletti, Patrizia Romuald. Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure. Pharmacological research. vol 114. 2017-12-26. PMID:27989838. |
gene expression analysis indicated a down-regulation of the n/ofq system and an up-regulation of the dyn system in the nucleus accumbens (nac), highlighting an opposite systems regulation in response to mdma exposure. |
2017-12-26 |
2023-08-13 |
rat |
| Miku Aoki, Yoshihisa Watanabe, Kanji Yoshimoto, Atsushi Tsujimura, Toshiro Yamamoto, Narisato Kanamura, Masaki Tanak. Involvement of serotonin 2C receptor RNA editing in accumbal neuropeptide Y expression and behavioural despair. The European journal of neuroscience. vol 43. issue 9. 2017-12-22. PMID:26950265. |
ini mice showed an enhanced behavioural despair in the forced swimming test, elevated sensitivity to the tricyclic antidepressant desipramine, and significantly decreased serotonin in the nucleus accumbens (nac), amygdala, and striatum. |
2017-12-22 |
2023-08-13 |
mouse |
| Laura H Corbit, Sarah C Fischbach, Patricia H Jana. Nucleus accumbens core and shell are differentially involved in general and outcome-specific forms of Pavlovian-instrumental transfer with alcohol and sucrose rewards. The European journal of neuroscience. vol 43. issue 9. 2017-12-22. PMID:26970240. |
these different forms of pit are mediated by distinct neural circuits involving the nucleus accumbens (nac) core and shell, respectively. |
2017-12-22 |
2023-08-13 |
rat |
| Egemen Kaya, Oguz Gozen, Muzeyyen Ugur, Ersin O Koylu, Lutfiye Kanit, Burcu Balka. Nicotine regulates cocaine-amphetamine-Regulated Transcript (Cart) in the mesocorticolimbic system. Synapse (New York, N.Y.). vol 70. issue 7. 2017-12-22. PMID:26990424. |
cart mrna and peptide levels in medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dst), amygdala (amg), lateral hypothalamic area (lha), and ventral tegmental area (vta) were measured by quantitative real-time pcr (qpcr) and western blot analysis, respectively. |
2017-12-22 |
2023-08-13 |
rat |
| Soomaayeh Heysieattalab, Nasser Naghdi, Narges Hosseinmardi, Mohammad-Reza Zarrindast, Abbas Haghparast, Habibeh Khoshboue. Methamphetamine-induced enhancement of hippocampal long-term potentiation is modulated by NMDA and GABA receptors in the shell-accumbens. Synapse (New York, N.Y.). vol 70. issue 8. 2017-12-22. PMID:27029021. |
as a substrate for dat, meth decreases dopamine uptake and increases dopamine efflux via the transporter in the target brain regions such as nucleus accumbens (nac) and hippocampus. |
2017-12-22 |
2023-08-13 |
rat |
| Rui Zhao, Jiaojiao Chen, Zhaoxiang Ren, Hui Shen, Xuechu Zhe. GSK-3β inhibitors reverse cocaine-induced synaptic transmission dysfunction in the nucleus accumbens. Synapse (New York, N.Y.). vol 70. issue 11. 2017-12-22. PMID:27377051. |
by employing single-unit recordings in vivo, we found that pretreatment with either sb216763 or licl for 15 min reversed the cocaine-inhibited firing frequency of medium spiny neuron (msn) in the nucleus accumbens (nac). |
2017-12-22 |
2023-08-13 |
rat |
| Fatemeh Sadeghzadeh, Vahab Babapour, Abbas Haghparas. Food deprivation facilitates reinstatement of morphine-induced conditioned place preference: Role of intra-accumbal dopamine D2-like receptors in associating reinstatement of morphine CPP with stress. Synapse (New York, N.Y.). vol 71. issue 4. 2017-12-22. PMID:27902847. |
about 104 adult male albino wistar rats weighing 200-280 g were bilaterally implanted by cannula into the nucleus accumbens (nac). |
2017-12-22 |
2023-08-13 |
rat |
| Jiangyong Ouyang, Ioana Carcea, Jennifer K Schiavo, Kymry T Jones, Ariana Rabinowitsch, Rhonda Kolaric, Soledad Cabeza de Vaca, Robert C Froemke, Kenneth D Car. Food restriction induces synaptic incorporation of calcium-permeable AMPA receptors in nucleus accumbens. The European journal of neuroscience. vol 45. issue 6. 2017-12-22. PMID:28112453. |
chronic food restriction potentiates behavioral and cellular responses to drugs of abuse and d-1 dopamine receptor agonists administered systemically or locally in the nucleus accumbens (nac). |
2017-12-22 |
2023-08-13 |
human |
| Lu Li, Chuchu Qiao, Gang Chen, Hongyan Qian, Ying Hou, Tao Li, Xinshe Li. Ifenprodil attenuates the acquisition and expression of methamphetamine-induced behavioral sensitization and activation of Ras-ERK1/2 cascade in the caudate putamen. Neuroscience. vol 335. 2017-12-21. PMID:27544406. |
then, using western blot, ras, perk1/2/erk1/2, and Δfosb levels in the prefrontal cortex (pfc), nucleus accumbens (nac), and caudate putamen (cpu) were detected. |
2017-12-21 |
2023-08-13 |
mouse |
| Angela M Henricks, Anthony L Berger, Janelle M Lugo, Lydia N Baxter-Potter, Kennedy V Bieniasz, Rebecca M Craft, Ryan J McLaughli. Sex differences in alcohol consumption and alterations in nucleus accumbens endocannabinoid mRNA in alcohol-dependent rats. Neuroscience. vol 335. 2017-12-21. PMID:27578612. |
thus, we evaluated sex differences in alcohol consumption, anxiety-like behavior, and ecb mrna expression in the nucleus accumbens (nac) of alcohol-dependent rats during acute withdrawal. |
2017-12-21 |
2023-08-13 |
rat |
| Yolanda Mateo, Kari A Johnson, Dan P Covey, Brady K Atwood, Hui-Ling Wang, Shiliang Zhang, Iness Gildish, Roger Cachope, Luigi Bellocchio, Manuel Guzmán, Marisela Morales, Joseph F Cheer, David M Lovinge. Endocannabinoid Actions on Cortical Terminals Orchestrate Local Modulation of Dopamine Release in the Nucleus Accumbens. Neuron. vol 96. issue 5. 2017-12-20. PMID:29216450. |
here we report that extracellular da increases induced by selective optogenetic activation of cholinergic neurons in the nucleus accumbens (nac) are inhibited by cb1 agonists and ecbs. |
2017-12-20 |
2023-08-13 |
Not clear |
| L Recinella, S Leone, C Ferrante, A Chiavaroli, C Di Nisio, S Martinotti, M Vacca, L Brunetti, G Orland. Effects of central fibroblast growth factor 21 (FGF21) in energy balance. Journal of biological regulators and homeostatic agents. vol 31. issue 3. 2017-12-14. PMID:28889722. |
in addition, we evaluated the effects of fgf21 on orexigenic [agouti-related peptide (agrp) and neuropeptide y (npy)] and anorexigenic [cocaine and amphetamine-regulated transcript (cart) and proopiomelanocortin (pomc)] peptides, in the hypothalamus, and dopamine (da) and serotonin (5-hydroxytriptamine, 5-ht) levels in nucleus accumbens (nac). |
2017-12-14 |
2023-08-13 |
rat |
| Bryan F Singer, Myranda A Bryan, Pavlo Popov, Terry E Robinson, Brandon J Aragon. Rapid induction of dopamine sensitization in the nucleus accumbens shell induced by a single injection of cocaine. Behavioural brain research. vol 324. 2017-12-13. PMID:28223145. |
repeated intermittent exposure to cocaine results in the neurochemical sensitization of dopamine (da) transmission within the nucleus accumbens (nac). |
2017-12-13 |
2023-08-13 |
rat |