All Relations between nac and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Kendra L Kobrin, Olivia Moody, Danielle T Arena, Catherine F Moore, Stephen C Heinrichs, Gary B Kapla. Acquisition of morphine conditioned place preference increases the dendritic complexity of nucleus accumbens core neurons. Addiction biology. vol 21. issue 6. 2018-01-16. PMID:26096355. effects of reward-context associative learning on nucleus accumbens (nac) dendritic morphology were studied using morphine conditioned place preference (cpp). 2018-01-16 2023-08-13 mouse
Xing Zhang, Veronica M Chiu, Ryan P Todd, Barbara A Sorg, Herbert H Hil. Neuronal metabolomics by ion mobility mass spectrometry in cocaine self-administering rats after early and late withdrawal. Analytical and bioanalytical chemistry. vol 408. issue 16. 2018-01-16. PMID:27108279. the neuronal metabolomes in rat striatum (str), prefrontal cortex (pfc), and nucleus accumbens (nac) were analyzed by hadamard transform ion mobility mass spectrometry (ht-imms) in order to reveal global and specific metabolic changes induced by cocaine self-administration after 1-day or 3-week withdrawal. 2018-01-16 2023-08-13 rat
Megan E Fox, Nathan T Rodeberg, R Mark Wightma. Reciprocal Catecholamine Changes during Opiate Exposure and Withdrawal. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27461081. we used fast-scan cyclic voltammetry in freely moving rats to measure real-time catecholamine overflow during acute morphine exposure and naloxone-precipitated withdrawal in two regions associated with the addiction cycle: the dopamine-dense nucleus accumbens (nac) and norepinephrine-rich ventral bed nucleus of the stria terminalis (vbnst). 2018-01-16 2023-08-13 rat
Daniel T Christian, Xiaoting Wang, Eugenia L Chen, Lakshya K Sehgal, Michael N Ghassemlou, Julia J Miao, Derenik Estepanian, Cameron H Araghi, Grace E Stutzmann, Marina E Wol. Dynamic Alterations of Rat Nucleus Accumbens Dendritic Spines over 2 Months of Abstinence from Extended-Access Cocaine Self-Administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27555380. chronic cocaine exposure influences the density and morphology of dendritic spines on medium spiny neurons (msns) in the nucleus accumbens (nac), a critical brain region for cocaine craving. 2018-01-16 2023-08-13 rat
Michael P Saddoris, Jonathan A Sugam, Regina M Carell. Prior Cocaine Experience Impairs Normal Phasic Dopamine Signals of Reward Value in Accumbens Shell. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 3. 2018-01-16. PMID:27604567. to quantify this, we voltammetrically measured real-time dopamine release in the nucleus accumbens (nac) core or shell while rats received unsignaled deliveries of either a small (1 pellet) or large (2 pellets) reward. 2018-01-16 2023-08-13 rat
Claudia Wolf, Holger Mohr, Esther K Diekhof, Henning Vieker, Roberto Goya-Maldonado, Sarah Trost, Bernd Krämer, Maria Keil, Elisabeth B Binder, Oliver Grube. CREB1 Genotype Modulates Adaptive Reward-Based Decisions in Humans. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 7. 2018-01-15. PMID:26045569. activity or expression changes of creb in the nucleus accumbens (nac) and orbital frontal cortex (ofc) interact with behavioral changes during reward-motivated learning. 2018-01-15 2023-08-13 human
Daniel C Castro, Rachel A Terry, Kent C Berridg. Orexin in Rostral Hotspot of Nucleus Accumbens Enhances Sucrose 'Liking' and Intake but Scopolamine in Caudal Shell Shifts 'Liking' Toward 'Disgust' and 'Fear'. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26787120. the nucleus accumbens (nac) contains a hedonic hotspot in the rostral half of medial shell, where opioid agonist microinjections are known to enhance positive hedonic orofacial reactions to the taste of sucrose ('liking' reactions). 2018-01-15 2023-08-13 Not clear
Steven F Merkel, Roshanak Razmpour, Evan M Lutton, Christopher S Tallarida, Nathan A Heldt, Lee Anne Cannella, Yuri Persidsky, Scott M Rawls, Servio H Ramire. Adolescent Traumatic Brain Injury Induces Chronic Mesolimbic Neuroinflammation with Concurrent Enhancement in the Rewarding Effects of Cocaine in Mice during Adulthood. Journal of neurotrauma. vol 34. issue 1. 2018-01-12. PMID:27026056. additionally, persistent neuroinflammatory responses were observed in the cortex, nucleus accumbens (nac), and ventral tegmental area post-cci-tbi. 2018-01-12 2023-08-13 mouse
Antonia Manduca, Michela Servadio, Ruth Damsteegt, Patrizia Campolongo, Louk Jmj Vanderschuren, Viviana Trezz. Dopaminergic Neurotransmission in the Nucleus Accumbens Modulates Social Play Behavior in Rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:26860202. in line with the rewarding properties of social play, we have previously identified the nucleus accumbens (nac) as an important site of action for endocannabinoid and opioid modulation of this behavior. 2018-01-09 2023-08-13 rat
Matthew Brodsky, Alec W Gibson, Denis Smirnov, Sunila G Nair, John F Neumaie. Striatal 5-HT6 Receptors Regulate Cocaine Reinforcement in a Pathway-Selective Manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:27032690. the nucleus accumbens (nac) in the ventral striatum integrates many neurochemical inputs including dopamine and serotonin projections from midbrain nuclei to modulate drug reward. 2018-01-09 2023-08-13 rat
Peter A Neumann, Yicun Wang, Yijin Yan, Yao Wang, Masago Ishikawa, Ranji Cui, Yanhua H Huang, Susan R Sesack, Oliver M Schlüter, Yan Don. Cocaine-Induced Synaptic Alterations in Thalamus to Nucleus Accumbens Projection. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:27074816. exposure to cocaine induces addiction-associated behaviors partially through remodeling neurocircuits in the nucleus accumbens (nac). 2018-01-09 2023-08-13 rat
G Faramarzi, M Zendehdel, A Haghparas. D1- and D2-like dopamine receptors within the nucleus accumbens contribute to stress-induced analgesia in formalin-related pain behaviours in rats. European journal of pain (London, England). vol 20. issue 9. 2018-01-09. PMID:27271035. meanwhile, it has been widely established that the mesolimbic dopamine pathway and nucleus accumbens (nac) have a profound role in pain modulation. 2018-01-09 2023-08-13 rat
Tracey M D'Cunha, Emilie Daoud, Damaris Rizzo, Audrey B Bishop, Melissa Russo, Gabrielle Mourra, Laurie Hamel, Firas Sedki, Uri Shale. Augmentation of Heroin Seeking Following Chronic Food Restriction in the Rat: Differential Role for Dopamine Transmission in the Nucleus Accumbens Shell and Core. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 5. 2018-01-08. PMID:27824052. here, we investigated the role of nucleus accumbens (nac) shell and core dopamine (da) in food restriction-induced augmentation of heroin seeking. 2018-01-08 2023-08-13 rat
Franca Lacroix, Annie Pettorelli, Jean-Marie N Maddux, Atyeh Heidari-Jam, Nadia Chaudhr. Varenicline Reduces Context-Induced Relapse to Alcohol-Seeking through Actions in the Nucleus Accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 5. 2018-01-08. PMID:27834390. neuropharmacological studies showed that context-induced relapse to alcohol-seeking was attenuated by bilateral microinfusion of varenicline (0.3 μl/side) into the nucleus accumbens (nac; 0 or 3.5 μg), but not the ventral tegmental area (0, 2 or 4 μg). 2018-01-08 2023-08-13 rat
Cyril Dejean, Mathieu Sitko, Paul Girardeau, Amine Bennabi, Stéphanie Caillé, Martine Cador, Thomas Boraud, Catherine Le Moin. Memories of Opiate Withdrawal Emotional States Correlate with Specific Gamma Oscillations in the Nucleus Accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 5. 2018-01-08. PMID:27922595. nucleus accumbens (nac) is a key structure for both acute withdrawal and withdrawal memories reactivation, but the nac neuron coding properties underpinning the expression of these memories remain largely unknown. 2018-01-08 2023-08-13 rat
William J Wright, Oliver M Schlüter, Yan Don. A Feedforward Inhibitory Circuit Mediated by CB1-Expressing Fast-Spiking Interneurons in the Nucleus Accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 5. 2018-01-08. PMID:27929113. the nucleus accumbens (nac) gates motivated behaviors through the functional output of principle medium spiny neurons (msns), whereas dysfunctional output of nac msns contributes to a variety of psychiatric disorders. 2018-01-08 2023-08-13 Not clear
Madalyn Hafenbreidel, Carolynn Rafa Todd, Devin Muelle. Infralimbic GluN2A-Containing NMDA Receptors Modulate Reconsolidation of Cocaine Self-Administration Memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 5. 2018-01-08. PMID:28042872. next, the glun2a-selective antagonist nvp or glun2b-selective antagonist ro25 was infused into il-mpfc or nucleus accumbens (nac) shell, another structure implicated in extinction, after four 45-min extinction sessions. 2018-01-08 2023-08-13 rat
Olli Kärkkäinen, Merja R Häkkinen, Seppo Auriola, Hannu Kautiainen, Jari Tiihonen, Markus Storvi. Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics. Alcohol (Fayetteville, N.Y.). vol 52. 2018-01-03. PMID:27139239. differences between the study groups were most prominent in the nucleus accumbens (nac), anterior cingulate cortex (acc), and anterior insula (ains). 2018-01-03 2023-08-13 human
Andrew D van der Vaart, Jennifer T Wolstenholme, Maren L Smith, Guy M Harris, Marcelo F Lopez, Aaron R Wolen, Howard C Becker, Robert W Williams, Michael F Mile. The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort. Alcohol (Fayetteville, N.Y.). vol 58. 2018-01-03. PMID:27838001. using affymetrix microarray analysis of prefrontal cortex (pfc) and nucleus accumbens (nac) rna, we compared cie expression responses to those seen following acute ethanol treatment, and to voluntary ethanol consumption. 2018-01-03 2023-08-13 mouse
Iku Tsutsui-Kimura, Yu Ohmura, Takayuki Yoshida, Mitsuhiro Yoshiok. Milnacipran affects mouse impulsive, aggressive, and depressive-like behaviors in a distinct dose-dependent manner. Journal of pharmacological sciences. vol 134. issue 3. 2018-01-03. PMID:28694090. a milnacipran dose of 10 mg/kg suppressed all behaviors, which was accompanied by increased dopamine and serotonin levels in the medial prefrontal cortex (mpfc) but not in the nucleus accumbens (nac). 2018-01-03 2023-08-13 mouse