| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S J Baracz, L M Parker, A S Suraev, N A Everett, A K Goodchild, I S McGregor, J L Cornis. Chronic Methamphetamine Self-Administration Dysregulates Oxytocin Plasma Levels and Oxytocin Receptor Fibre Density in the Nucleus Accumbens Core and Subthalamic Nucleus of the Rat. Journal of neuroendocrinology. vol 28. issue 4. 2018-02-08. PMID:26563756. |
recent findings have implicated the nucleus accumbens (nac) core and subthalamic nucleus (sth) in oxytocin modulation of acute meth reward and relapse to meth-seeking behaviour. |
2018-02-08 |
2023-08-13 |
rat |
| Anna Brancato, Dana Bregman, H Francisica Ahn, Madeline L Pfau, Caroline Menard, Carla Cannizzaro, Scott J Russo, Georgia E Hode. Sub-chronic variable stress induces sex-specific effects on glutamatergic synapses in the nucleus accumbens. Neuroscience. vol 350. 2018-02-06. PMID:28323008. |
accumulating evidence indicates that altered neuroplasticity of excitatory synapses in the nucleus accumbens (nac) is a key pathophysiological feature of susceptibility to social stress in males. |
2018-02-06 |
2023-08-13 |
mouse |
| Erin S Calipari, Arthur Godino, Emily G Peck, Marine Salery, Nicholas L Mervosh, Joseph A Landry, Scott J Russo, Yasmin L Hurd, Eric J Nestler, Drew D Kiral. Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine. Nature communications. vol 9. issue 1. 2018-02-02. PMID:29339724. |
here we report that g-csf potentiates cocaine-induced increases in neural activity in the nucleus accumbens (nac) and prefrontal cortex. |
2018-02-02 |
2023-08-13 |
Not clear |
| Yi-Jing Li, Xing-Jie Ping, Chong Qi, Fang Shen, Lin-Lin Sun, Xiao-Wei Sun, Fei-Fei Ge, Guo-Gang Xing, Cai-Lian Cu. Re-exposure to morphine-associated context facilitated long-term potentiation in the vSUB-NAc glutamatergic pathway via GluN2B-containing receptor activation. Addiction biology. vol 22. issue 2. 2018-01-30. PMID:26692025. |
the glutamatergic projection from the ventral subiculum of the hippocampus (vsub) to the nucleus accumbens (nac) shell has been reported to play a key role in drug-related behavior. |
2018-01-30 |
2023-08-13 |
rat |
| María S García-Gutiérrez, Francisco Navarrete, Auxiliadora Aracil, Adrián Bartoll, Isabel Martínez-Gras, José L Lanciego, Gabriel Rubio, Jorge Manzanare. Increased vulnerability to ethanol consumption in adolescent maternal separated mice. Addiction biology. vol 21. issue 4. 2018-01-29. PMID:25988842. |
alterations of the corticotropin-releasing factor (crf), glucocorticoid receptor (nr3c1), tyrosine hydroxylase (th), mu-opioid receptor (mor), brain-derived neurotrophic factor (bdnf), neuronal nuclei (neun), microtubule-associated protein 2 (map2) and neurofilament heavy (nf200)-immunoreactive fibers were studied in the paraventricular nucleus of the hypothalamus (pvn), ventral tegmental area (vta), nucleus accumbens (nac) or hippocampus (hip). |
2018-01-29 |
2023-08-13 |
mouse |
| Travis M Moschak, Regina M Carell. Impulsive Rats Exhibit Blunted Dopamine Release Dynamics during a Delay Discounting Task Independent of Cocaine History. eNeuro. vol 4. issue 2. 2018-01-29. PMID:28451642. |
individual differences in impulsivity on the delay discounting task are reflected in differences in neural function, including in the nucleus accumbens (nac) core. |
2018-01-29 |
2023-08-13 |
rat |
| Yo Oishi, Qi Xu, Lu Wang, Bin-Jia Zhang, Koji Takahashi, Yohko Takata, Yan-Jia Luo, Yoan Cherasse, Serge N Schiffmann, Alban de Kerchove d'Exaerde, Yoshihiro Urade, Wei-Min Qu, Zhi-Li Huang, Michael Lazaru. Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice. Nature communications. vol 8. issue 1. 2018-01-29. PMID:28963505. |
previous studies suggest that adenosine has a role affecting behavioural arousal in the nucleus accumbens (nac), a brain area critical for reinforcement and reward. |
2018-01-29 |
2023-08-13 |
mouse |
| Diane M Damez-Werno, HaoSheng Sun, Kimberly N Scobie, Ningyi Shao, Jaclyn Rabkin, Caroline Dias, Erin S Calipari, Ian Maze, Catherine J Pena, Deena M Walker, Michael E Cahill, Ramesh Chandra, Amy Gancarz, Ezekiell Mouzon, Joseph A Landry, Hannah Cates, Mary-Kay Lobo, David Dietz, C David Allis, Ernesto Guccione, Gustavo Turecki, Paola Defilippi, Rachael L Neve, Yasmin L Hurd, Li Shen, Eric J Nestle. Histone arginine methylation in cocaine action in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 34. 2018-01-26. PMID:27506785. |
repeated cocaine exposure regulates transcriptional regulation within the nucleus accumbens (nac), and epigenetic mechanisms-such as histone acetylation and methylation on lys residues-have been linked to these lasting actions of cocaine. |
2018-01-26 |
2023-08-13 |
mouse |
| Linde Boekhoudt, Azar Omrani, Mieneke C M Luijendijk, Inge G Wolterink-Donselaar, Ellen C Wijbrans, Geoffrey van der Plasse, Roger A H Ada. Chemogenetic activation of dopamine neurons in the ventral tegmental area, but not substantia nigra, induces hyperactivity in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 11. 2018-01-26. PMID:27712862. |
furthermore, this hyperactive phenotype was replicated by selective activation of the neuronal pathway from vta to the nucleus accumbens (nac). |
2018-01-26 |
2023-08-13 |
rat |
| S Nakanishi, T Hikida, S Yawat. Distinct dopaminergic control of the direct and indirect pathways in reward-based and avoidance learning behaviors. Neuroscience. vol 282. 2018-01-26. PMID:24769227. |
the nucleus accumbens (nac) plays a pivotal role in reward and aversive learning and learning flexibility. |
2018-01-26 |
2023-08-13 |
mouse |
| J J Walsh, M H Ha. The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context. Neuroscience. vol 282. 2018-01-26. PMID:24931766. |
these neurons project to different brain regions, including the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the amygdala. |
2018-01-26 |
2023-08-13 |
Not clear |
| Torry S Dennis, Kevin D Beck, Tara P Cominski, Samara A M Bobzean, Eldo V Kuzhikandathil, Richard J Servatius, Linda I Perrott. Exposure to morphine-associated cues increases mu opioid receptor mRNA expression in the nucleus accumbens of Wistar Kyoto rats. Behavioural brain research. vol 313. 2018-01-25. PMID:27421830. |
conditioned responding to drug-associated cues is linked with alterations in the activation of mu opioid receptors (mor) and kappa opioid receptors (kor) in the nucleus accumbens (nac). |
2018-01-25 |
2023-08-13 |
rat |
| Junran Cao, Tanseli Nesil, Shaolin Wang, Sulie L Chang, Ming D L. Expression profile of nicotinic acetylcholine receptor subunits in the brain of HIV-1 transgenic rats given chronic nicotine treatment. Journal of neurovirology. vol 22. issue 5. 2018-01-24. PMID:27056721. |
we found that nachr subunits were differentially expressed in various brain regions in hiv-1tg rats compared to f344 control rats, with more subunits altered in the ventral tegmental area (vta) and nucleus accumbens (nac) of the hiv-1tg rats than in other brain regions. |
2018-01-24 |
2023-08-13 |
rat |
| Xiaoqun Zhang, Ning Yao, Karima Chergu. The GABAA receptor agonist muscimol induces an age- and region-dependent form of long-term depression in the mouse striatum. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 9. 2018-01-19. PMID:27531838. |
several forms of long-term depression (ltd) of glutamatergic synaptic transmission have been identified in the dorsal striatum and in the nucleus accumbens (nac). |
2018-01-19 |
2023-08-13 |
mouse |
| Salil Saurav Pathak, Swati Maitra, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylases of JMJD2 or KDM4 Family are Important Epigenetic Regulators in Reward Circuitry in the Etiopathology of Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 4. 2018-01-19. PMID:27711046. |
recent research shows dysregulation in epigenetic regulatory mechanisms, particularly the transcriptionally repressive di- and tri-methylation of histone 3 lysine 9 (h3k9me2/me3) in nucleus accumbens (nac), a critical region of the reward pathway involved in the development of anhedonia, the hallmark of depression. |
2018-01-19 |
2023-08-13 |
mouse |
| Sonya Neto, Ramya Varatharajan, Kevin Joseph, Andreas Mose. Nasal administration of leptin dose-dependently increases dopamine and serotonin outflow in the rat nucleus accumbens. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 11. 2018-01-18. PMID:27412669. |
therefore, the purpose of this study was to assess whether and to what extent an acute intranasal application of leptin is able to modulate monoamine neurotransmitters in the nucleus accumbens (nac). |
2018-01-18 |
2023-08-13 |
rat |
| Melissa L Perreault, Ahmed Hasbi, Maurice Y F Shen, Theresa Fan, Gemma Navarro, Paul J Fletcher, Rafael Franco, José L Lanciego, Susan R Georg. Disruption of a dopamine receptor complex amplifies the actions of cocaine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 9. 2018-01-18. PMID:27480020. |
cocaine-induced increases in dopamine signaling in nucleus accumbens (nac) play a significant role in cocaine seeking behavior. |
2018-01-18 |
2023-08-13 |
rat |
| Tom Macpherson, Makiko Morita, Yanyan Wang, Toshikuni Sasaoka, Akira Sawa, Takatoshi Hikid. Nucleus accumbens dopamine D2-receptor expressing neurons control behavioral flexibility in a place discrimination task in the IntelliCage. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 7. 2018-01-17. PMID:27317196. |
considerable evidence has demonstrated a critical role for the nucleus accumbens (nac) in the acquisition and flexibility of behavioral strategies. |
2018-01-17 |
2023-08-13 |
mouse |
| Yukihisa Funamizu, Haruo Nishijima, Tatsuya Ueno, Shinya Ueno, Hiroki Mizukami, Soroku Yagihashi, Masahiko Tomiyam. Morphological dendritic spine changes of medium spiny neurons in the nucleus accumbens in 6-hydroxydopamine-lesioned rats treated with levodopa. Neuroscience research. vol 121. 2018-01-17. PMID:28392304. |
the mechanisms of dopamine dysregulation syndrome (dds) in parkinson's disease (pd) remain unclear, although it is known that the nucleus accumbens (nac) plays a role in its development. |
2018-01-17 |
2023-08-13 |
rat |
| Marie-Line Reynaert, Jordan Marrocco, Jérôme Mairesse, Luana Lionetto, Maurizio Simmaco, Lucie Deruyter, Delphine Allorge, Anna Moles, Anna Pittaluga, Stefania Maccari, Sara Morley-Fletcher, Gilles Van Camp, Ferdinando Nicolett. Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner. Addiction biology. vol 21. issue 6. 2018-01-16. PMID:26011513. |
male prs rats also show increases in plasma dihydrotestosterone (dht) levels and dopamine (da) levels in the nucleus accumbens (nac), and reductions in 5-hydroxytryptamine (5-ht) levels in the nac and prefrontal cortex (pfc). |
2018-01-16 |
2023-08-13 |
rat |