| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacqueline F McGinty, James M Oti. Heterogeneity in the Paraventricular Thalamus: The Traffic Light of Motivated Behaviors. Frontiers in behavioral neuroscience. vol 14. 2020-11-13. PMID:33177999. |
although the function of pvt in influencing reward-seeking is poorly understood, recent studies show that forebrain and hypothalamic inputs to, and nucleus accumbens (nac) and amygdalar outputs from, pvt are strongly implicated in pvt responses to conditioned and appetitive or aversive stimuli that determine whether an animal will approach or avoid specific rewards. |
2020-11-13 |
2023-08-13 |
Not clear |
| Ashley M Fennell, Elizabeth G Pitts, Lacey L Sexton, Mark J Ferri. Phasic Dopamine Release Magnitude Tracks Individual Differences in Sensitization of Locomotor Response following a History of Nicotine Exposure. Scientific reports. vol 10. issue 1. 2020-11-12. PMID:31932634. |
given the role of mesolimbic dopamine projections in motivation, substance use disorder, and drug relapse, we examined the effect of repeated nicotine on rapid dopamine signals in the nucleus accumbens (nac) of rats. |
2020-11-12 |
2023-08-13 |
rat |
| Takatoshi Hikida, Shuhei Yao, Tom Macpherson, Ayumi Fukakusa, Makiko Morita, Haruhide Kimura, Keisuke Hirai, Tatsuya Ando, Hiroyoshi Toyoshiba, Akira Saw. Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex. Scientific reports. vol 10. issue 1. 2020-11-10. PMID:32020036. |
within this circuit, two distinct nucleus accumbens (nac) output neuron types, dopamine d1 or d2 receptor-expressing neurons, dynamically control the flow of information through basal ganglia nuclei that eventually project back to the mpfc to complete the loop. |
2020-11-10 |
2023-08-13 |
mouse |
| Vivien Zell, Thomas Steinkellner, Nick G Hollon, Shelley M Warlow, Elizabeth Souter, Lauren Faget, Avery C Hunker, Xin Jin, Larry S Zweifel, Thomas S Hnask. VTA Glutamate Neuron Activity Drives Positive Reinforcement Absent Dopamine Co-release. Neuron. vol 107. issue 5. 2020-11-09. PMID:32610039. |
both approaches led to loss of th expression in vta glutamate neurons and loss of da release from their distal terminals in nucleus accumbens (nac). |
2020-11-09 |
2023-08-13 |
mouse |
| Xi Fang, Chun Yang, Shan Li, Gaofeng Zhan, Jie Zhang, Niannian Huang, Xiangxi Du, Hui Xu, Kenji Hashimoto, Ailin Lu. Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury. European archives of psychiatry and clinical neuroscience. vol 270. issue 2. 2020-11-06. PMID:29882089. |
in contrast, tissue levels of bdnf in the nucleus accumbens (nac) of rats with an anhedonia-like phenotype were higher compared with those of rats without anhedonia-like phenotype and sham-operated rats. |
2020-11-06 |
2023-08-13 |
rat |
| Qingxiao Hong, Jing Liu, Zi Lin, Dingding Zhuang, Wenjin Xu, Zemin Xu, Miaojun Lai, Huaqiang Zhu, Wenhua Zhou, Huifen Li. Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats. Molecular medicine reports. vol 21. issue 1. 2020-11-06. PMID:31939625. |
chromatin immunoprecipitation followed by reverse transcription‑quantitative pcr (rt‑qpcr) was used to detect the accumulation of h3k9ac on brg1 in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) following heroin self‑administration. |
2020-11-06 |
2023-08-13 |
rat |
| Yasuto Kunii, Mizuki Hino, Junya Matsumoto, Atsuko Nagaoka, Hiroyuki Nawa, Akiyoshi Kakita, Hiroyasu Akatsu, Yoshio Hashizume, Hirooki Yab. Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31619735. |
in this study, protein expression levels of darpp-32 and can were measured by enzyme-linked immunosorbent assay (elisa) in the prefrontal cortex (pfc), and nucleus accumbens (nac) of 49 postmortem samples from subjects with schizophrenia, bipolar disorder, and normal controls. |
2020-11-02 |
2023-08-13 |
human |
| Lili Niu, Yanchen Guo, Zhengrong Lin, Zhe Shi, Tianyuan Bian, Lin Qi, Long Meng, Anthony A Grace, Hairong Zheng, Ti-Fei Yua. Noninvasive ultrasound deep brain stimulation of nucleus accumbens induces behavioral avoidance. Science China. Life sciences. vol 63. issue 9. 2020-11-02. PMID:32180109. |
the present study investigates the behavioral alterations resulting from ultrasound stimulation on the nucleus accumbens (nac) in freely moving mice. |
2020-11-02 |
2023-08-13 |
mouse |
| Hope Kronman, Felix Richter, Benoit Labonté, Ramesh Chandra, Shan Zhao, Gabriel Hoffman, Mary Kay Lobo, Eric E Schadt, Eric J Nestle. Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons. Scientific reports. vol 9. issue 1. 2020-10-30. PMID:31171808. |
finally, d1 and d2 dopamine receptor-expressing medium spiny neurons (msns) of the nucleus accumbens (nac) are fundamental to neuropsychiatric traits but have only a short list of canonical surface markers. |
2020-10-30 |
2023-08-13 |
mouse |
| Francisco J Pavón, Antonia Serrano, David G Stouffer, Ilham Polis, Marisa Roberto, Benjamin F Cravatt, Rémi Martin-Fardon, Fernando Rodríguez de Fonseca, Loren H Parson. Ethanol-induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30421483. |
extracellular levels of endocannabinoids and relevant neurotransmitters were measured by in vivo microdialysis in the nucleus accumbens (nac) of faah knockout (ko) and wild-type (wt) mice during an ethanol (etoh; 2 g/kg, ip) challenge in etoh-naive and repeated (r) etoh-treated mice. |
2020-10-28 |
2023-08-13 |
mouse |
| Yozo Ishiuj. Addiction and the itch-scratch cycle. What do they have in common? Experimental dermatology. vol 28. issue 12. 2020-10-28. PMID:31482585. |
reward systems, including the ventral tegmental area (vta), nucleus accumbens (nac) and striatum, are important for brain processing of both addiction and itch. |
2020-10-28 |
2023-08-13 |
human |
| Chunhui Yang, Yiqing Qiu, Xiaowu Hu, Jianchun Chen, Yina Wu, Xi W. The Effect of High-Frequency Electrical Stimulation of Bilateral Nucleus Accumbens on the Behavior of Morphine-Induced Conditioned Place Preference Rats at Extinction and Reinstatement Phases. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-10-28. PMID:33101448. |
to explore the optimal time points for deep brain stimulation (dbs) on the treatment of morphine addiction and its possible mechanisms by investigating how high-frequency stimulation (hfs) in bilateral nucleus accumbens (nac) at different time points influences the addictive behaviors of rats with drug addiction. |
2020-10-28 |
2023-08-13 |
rat |
| Shunji Yamada, Mohammad Shyful Islam, Nienke van Kooten, Sonny Bovee, Yoon-Mi Oh, Atsushi Tsujimura, Yoshihisa Watanabe, Masaki Tanak. Neuropeptide Y neurons in the nucleus accumbens modulate anxiety-like behavior. Experimental neurology. vol 327. 2020-10-27. PMID:32014439. |
neuropeptide y (npy) is a 36-amino acid neuropeptide that is widely expressed in the central nervous system, including the cerebral cortex, nucleus accumbens (nac) and hypothalamus. |
2020-10-27 |
2023-08-13 |
mouse |
| A M Cunha, F G Teixeira, M R Guimarães, M Esteves, J Pereira-Mendes, A R Soares, A Almeida, N Sousa, A J Salgado, H Leite-Almeid. Unilateral accumbal dopamine depletion affects decision-making in a side-specific manner. Experimental neurology. vol 327. 2020-10-27. PMID:32027930. |
nucleus accumbens (nac) is affected in pd and due to its well-known involvement in motivation is an interesting target in this context. |
2020-10-27 |
2023-08-13 |
rat |
| Fiona Limanaqi, Carla Letizia Busceti, Francesca Biagioni, Francesco Fornai, Stefano Puglisi-Allegr. Autophagy-Based Hypothesis on the Role of Brain Catecholamine Response During Stress. Frontiers in psychiatry. vol 11. 2020-10-24. PMID:33093837. |
lc-ne projections are dominant in controlling the forebrain da-targeted areas, such as the nucleus accumbens (nac) and medial pre-frontal cortex (mpfc). |
2020-10-24 |
2023-08-13 |
Not clear |
| Bianca C G Lisboa, Katia C Oliveira, Ana Carolina Tahira, André Rocha Barbosa, Arthur Sant'Anna Feltrin, Gisele Gouveia, Luzia Lima, Ana Cecília Feio Dos Santos, David Correa Martins, Renato David Puga, Ariane Cristine Moretto, Carlos Alberto De Bragança Pereira, Beny Lafer, Renata Elaine Paraizo Leite, Renata Eloah De Lucena Ferretti-Rebustini, Jose Marcelo Farfel, Lea Tenenholz Grinberg, Wilson Jacob-Filho, Euripedes Constantino Miguel, Marcelo Queiroz Hoexter, Helena Brentan. Initial findings of striatum tripartite model in OCD brain samples based on transcriptome analysis. Scientific reports. vol 9. issue 1. 2020-10-20. PMID:30816141. |
the transcriptomes of 3 separate striatal areas (putamen (pt), caudate nucleus (cn) and accumbens nucleus (nac)) from postmortem brain tissue were compared between 6 ocd and 8 control cases. |
2020-10-20 |
2023-08-13 |
Not clear |
| Paul Francke, Lena J Tiedemann, Mareike M Menz, Judith Beck, Christian Büchel, Stefanie Brasse. Mesolimbic white matter connectivity mediates the preference for sweet food. Scientific reports. vol 9. issue 1. 2020-10-20. PMID:30867529. |
dopaminergic brain structures like the nucleus accumbens (nac) are thought to encode the incentive salience of palatable foods motivating appetitive behaviour. |
2020-10-20 |
2023-08-13 |
human |
| Kai An, Huan Zhao, Ying Miao, Qi Xu, Yu-Fei Li, Yu-Qian Ma, Yi-Ming Shi, Jia-Wei Shen, Jian-Jun Meng, Yong-Gang Yao, Zhi Zhang, Ju-Tao Chen, Jin Bao, Mei Zhang, Tian Xu. A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice. Nature neuroscience. vol 23. issue 7. 2020-10-07. PMID:32483349. |
this effect was mediated by a neural pathway from retinal melanopsin-expressing ganglion cells to the dorsal perihabenular nucleus (dphb) to the nucleus accumbens (nac). |
2020-10-07 |
2023-08-13 |
mouse |
| Jia-Xi Wang, Jin-Ying Zhuang, Lulu Fu, Qin Lei, Mingxia Fan, Weidong Zhan. How ovarian hormones influence the behavioral activation and inhibition system through the dopamine pathway. PloS one. vol 15. issue 8. 2020-10-07. PMID:32790683. |
on the neural level, we demonstrated bas was related with the vta pathway, included brain reward regions of nucleus accumbens (nac) and orbitofrontal cortex (ofc). |
2020-10-07 |
2023-08-13 |
Not clear |
| Mohammad-Reza Zarrindast, Fatemeh Khakpa. State-dependent memory and its modulation by different brain areas and neurotransmitters. EXCLI journal. vol 19. 2020-10-06. PMID:33013265. |
our review of the literature revealed that: (a) re-administration of drugs on the same state induce state-dependent memory; (b) many neurotransmitters induce endogenous state-dependent memory; (c) there are cross state-dependent learning and memory between some drugs; (d) some sites of the brain including the ca1 areas of the hippocampus, central nucleus of the amygdala (cea), septum, ventral tegmental area (vta), and nucleus accumbens (nac) are involved in state-dependent memory. |
2020-10-06 |
2023-08-13 |
human |