| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lihua Yang, Ningning Guo, Wei Fan, Chunmin Ni, Mengbing Huang, Liping Bai, Le Zhang, Xianwen Zhang, Yunbo Wen, Ye Li, Xiaoshuang Zhou, Jie Ba. Thioredoxin-1 blocks methamphetamine-induced injury in brain through inhibiting endoplasmic reticulum and mitochondria-mediated apoptosis in mice. Neurotoxicology. vol 78. 2021-04-21. PMID:32203791. |
then we detected and found that meth increased the expression of n-methyl-d-asparate (nmda) receptor subunit 2b (nr2b) and the level of glutamate (glu) in the ventral tegmental area (vta) and nucleus accumbens (nac), while trx-1 overexpression suppressed the increases. |
2021-04-21 |
2023-08-13 |
mouse |
| Francesca Mottarlini, Giorgia Bottan, Benedetta Tarenzi, Alessandra Colciago, Fabio Fumagalli, Lucia Caffin. Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats. Nutrients. vol 12. issue 12. 2021-04-21. PMID:33260714. |
an patients exhibit an altered activation of nucleus accumbens (nac), revealing a dysfunctional mesocorticolimbic reward circuitry in an. |
2021-04-21 |
2023-08-13 |
rat |
| Joseph Clerke, Patricia Preston-Ferrer, Ioannis S Zouridis, Audrey Tissot, Laura Batti, Fabian F Voigt, Stephane Pagès, Andrea Burgalossi, Manuel Mamel. Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal. Frontiers in synaptic neuroscience. vol 13. 2021-04-21. PMID:33867967. |
vta neurons receiving lhb inputs project their axons to medial prefrontal cortex (mpfc), nucleus accumbens (nac), and lateral hypothalamus (lh). |
2021-04-21 |
2023-08-13 |
mouse |
| Xiaolu Yu, Mannan Abdul, Bing-Qian Fan, Lilu Zhang, Xing Lin, Yan Wu, Hui Fu, Qisi Lin, Hao Men. The release of exosomes in the medial prefrontal cortex and nucleus accumbens brain regions of chronic constriction injury (CCI) model mice could elevate the pain sensation. Neuroscience letters. vol 723. 2021-04-19. PMID:31981720. |
the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) brain regions are known to involve in pain modulation. |
2021-04-19 |
2023-08-13 |
mouse |
| Terra A Schall, William J Wright, Yan Don. Nucleus accumbens fast-spiking interneurons in motivational and addictive behaviors. Molecular psychiatry. vol 26. issue 1. 2021-04-14. PMID:32071384. |
the development of drug addiction is associated with functional adaptations within the reward circuitry, within which the nucleus accumbens (nac) is anatomically positioned as an interface between motivational salience and behavioral output. |
2021-04-14 |
2023-08-13 |
Not clear |
| D L Marinus Oterdoom, Renske Lok, André P van Beek, Wilfred F A den Dunnen, Marloes Emous, J Marc C van Dijk, Gertjan van Dij. Deep Brain Stimulation in the Nucleus Accumbens for Binge Eating Disorder: a Study in Rats. Obesity surgery. vol 30. issue 10. 2021-04-14. PMID:32451916. |
we therefore assessed effect of dbs of the nucleus accumbens (nac) in a rat model of bed. |
2021-04-14 |
2023-08-13 |
rat |
| Sharlene D Newman, Hu Cheng, Dae-Jin Kim, Ashley Schnakenberg-Martin, Ulrike Dydak, Shalmali Dharmadhikari, William Hetrick, Brian O'Donnel. An investigation of the relationship between glutamate and resting state connectivity in chronic cannabis users. Brain imaging and behavior. vol 14. issue 5. 2021-04-13. PMID:31302844. |
the aims of the current preliminary study were to: 1) determine whether dorsal anterior cingulate cortex (dacc) glu is related to rsfc between the dacc and two nodes of the reward network, the nucleus accumbens (nac) and hippocampus (hp); and 2) determine whether cb use interacts with the relationship between dacc glu and rsfc. |
2021-04-13 |
2023-08-13 |
human |
| Bryan Cruz, Luis M Carcoba, Rodolfo J Flores, Evangelina J Espinoza, Arbi Nazarian, Laura E O'Del. Insulin restores the neurochemical effects of nicotine in the mesolimbic pathway of diabetic rats. Journal of neurochemistry. vol 156. issue 2. 2021-04-08. PMID:32562571. |
two-weeks later, dialysis probes were implanted into the nucleus accumbens (nac) and ipsilateral ventral tegmental area (vta). |
2021-04-08 |
2023-08-13 |
rat |
| Mina Goudarzi, Arezo Nahavandi, Soraya Mehrabi, Maryam Eslami, Ali Shahbazi, Mahmoud Barat. Valproic acid administration exerts protective effects against stress-related anhedonia in rats. Journal of chemical neuroanatomy. vol 105. 2021-04-02. PMID:32061998. |
moreover, they had significantly higher levels of hdac3 and mc4r expression in the nucleus accumbens (nac) compared to the non-stressed group (p < 0.01). |
2021-04-02 |
2023-08-13 |
rat |
| Shaoqiang Han, Qian Cui, Xiao Wang, Yuyan Chen, Di Li, Liang Li, Xiaonan Guo, Yun-Shuang Fan, Jing Guo, Wei Sheng, Fengmei Lu, Zongling He, Huafu Che. The anhedonia is differently modulated by structural covariance network of NAc in bipolar disorder and major depressive disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 99. 2021-03-31. PMID:31962188. |
considering the vital role of nucleus accumbens (nac) in the anhedonia, we constructed the structural covariance network of nac for each subject. |
2021-03-31 |
2023-08-13 |
human |
| X Li, L-S Xu, Y-F Xu, Q Yang, Z-X Fang, M Yao, W-Y Che. The gene regulatory network in different brain regions of neuropathic pain mouse models. European review for medical and pharmacological sciences. vol 24. issue 9. 2021-03-31. PMID:32432769. |
neuropathic pain is often associated with structural and functional abnormalities in multiple brain regions, and its regulation has been shown to correspond with the forebrain, including nucleus accumbens (nac), medial prefrontal cortex (mpfc) and periaqueductal gray (pag). |
2021-03-31 |
2023-08-13 |
mouse |
| Emilie Werlen, Soon-Lim Shin, Francois Gastambide, Jennifer Francois, Mark D Tricklebank, Hugh M Marston, John R Huxter, Gary Gilmour, Mark E Walto. Amphetamine disrupts haemodynamic correlates of prediction errors in nucleus accumbens and orbitofrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 5. 2021-03-30. PMID:31703234. |
to help address this issue, we used a translational technique, oxygen amperometry, to record haemodynamic signals in the nucleus accumbens (nac) and orbitofrontal cortex (ofc), while freely moving rats performed a probabilistic pavlovian learning task. |
2021-03-30 |
2023-08-13 |
human |
| Adriana Castro-Zavala, Ana Martín-Sánchez, Miguel Ángel Luján, Olga Valverd. Maternal separation increases cocaine intake through a mechanism involving plasticity in glutamate signalling. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32329565. |
we also investigated the subsequent alterations on glur2, glur1, camp response element-binding (creb), and creb-phosphorylation (pcreb) in ventral tegmental area (vta) and nucleus accumbens (nac) induced by both msew and cocaine sa. |
2021-03-25 |
2023-08-13 |
mouse |
| Ju Hwan Yang, Sumin Sohn, Sunghyun Kim, Jieun Kim, Jeong Hwan Oh, In Soo Ryu, Bok Soon Go, Eun Sang Cho. Repeated nicotine exposure increases the intracellular interaction between ERK-mGluR5 in the nucleus accumbens more in adult than adolescent rats. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32339332. |
we investigated the difference in the degree of interaction between extracellular signal-regulated kinase (erk) and metabotropic glutamate receptor subtype 5 (mglur5) in the nucleus accumbens (nac) after repeated exposure to nicotine in adult and adolescent rats. |
2021-03-25 |
2023-08-13 |
rat |
| Chao Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Shuyue Wang, Yeerfan Jiaerken, Xiao Luo, Kaicheng Li, Qingze Zeng, Cheng Zhou, Yihong Yang, Minming Zhan. Increased striatal functional connectivity is associated with improved smoking cessation outcomes: A preliminary study. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32436626. |
significant interaction effects were detected: (1) between left nucleus accumbens (nac) and left orbitofrontal cortex (ofc), insula, inferior frontal gyrus (ifg), and bilateral precuneus; (2) between right nac and left insula, ifg, and bilateral dorsolateral prefrontal cortex (dlpfc); and (3) between bilateral putamen and left precuneus. |
2021-03-25 |
2023-08-13 |
human |
| Inês M Amaral, Cristina Lemos, Isabella Cera, Georg Dechant, Alex Hofer, Rana El Rawa. Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Versus Social Interaction Reward. International journal of molecular sciences. vol 22. issue 1. 2021-03-25. PMID:33396297. |
evidence suggests that pka activity in the nucleus accumbens (nac) plays an essential role in reward-related learning. |
2021-03-25 |
2023-08-13 |
rat |
| Hui Qiao, Sha Yang, Chang Xu, Xin-Ming Ma, Shu-Cheng A. Involvement of D2 receptor in the NAc in chronic unpredictable stress-induced depression-like behaviors. Stress (Amsterdam, Netherlands). vol 23. issue 3. 2021-03-24. PMID:31556781. |
d2 receptors (d2rs) located in both pre- and postsynaptic membranes of medium spiny neurons (msns) in the nucleus accumbens (nac) are involved in the stress response and associated behaviors. |
2021-03-24 |
2023-08-13 |
mouse |
| Hannah Benedictine Maier, Meraj Neyazi, Alexandra Neyazi, Thomas Hillemacher, Hansi Pathak, Mathias Rhein, Stefan Bleich, Koral Goltseker, Yossi Sadot-Sogrin, Oren Even-Chen, Helge Frieling, Segev Bara. Alcohol consumption alters Gdnf promoter methylation and expression in rats. Journal of psychiatric research. vol 121. 2021-03-24. PMID:31710958. |
whole blood, nucleus accumbens (nac) and ventral tegmental area (vta) were collected immediately after the last 24 h of an alcohol-drinking session (alcohol group, ag) or 24 h after withdrawal (withdrawal group, wg). |
2021-03-24 |
2023-08-13 |
rat |
| Chia-Chun Hsu, Teresa E Madsen, Elizabeth O'Gorman, Shannon L Gourley, Donald G Rainni. Reward-related dynamical coupling between basolateral amygdala and nucleus accumbens. Brain structure & function. vol 225. issue 6. 2021-03-24. PMID:32556583. |
neuronal projections from the basolateral amygdala (bla) to the nucleus accumbens (nac) play an important role in processing reward-related cues. |
2021-03-24 |
2023-08-13 |
rat |
| Christopher K Lafferty, Angela K Yang, Jesse A Mendoza, Jonathan P Brit. Nucleus Accumbens Cell Type- and Input-Specific Suppression of Unproductive Reward Seeking. Cell reports. vol 30. issue 11. 2021-03-23. PMID:32187545. |
the nucleus accumbens (nac) contributes to behavioral inhibition and compulsions, but circuit mechanisms are unclear. |
2021-03-23 |
2023-08-13 |
mouse |