| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Munehiro Masuzawa, Shinichi Nakao, Etsuko Miyamoto, Makiko Yamada, Kouhei Murao, Kenichirou Nishi, Koh Shing. Pentobarbital inhibits ketamine-induced dopamine release in the rat nucleus accumbens: a microdialysis study. Anesthesia and analgesia. vol 96. issue 1. 2003-01-21. PMID:12505941. |
dopamine release in the nucleus accumbens (nac) plays a crucial role in the actions of various psychotropic and addictive drugs. |
2003-01-21 |
2023-08-12 |
rat |
| Pepe J Hernandez, Kenneth Sadeghian, Ann E Kelle. Early consolidation of instrumental learning requires protein synthesis in the nucleus accumbens. Nature neuroscience. vol 5. issue 12. 2003-01-03. PMID:12426572. |
plasticity within the nucleus accumbens (nac), a major component of the ventral striatum, is thought to mediate instrumental learning processes and many aspects of drug addiction. |
2003-01-03 |
2023-08-12 |
rat |
| F S Hall, S Ghaed, A Pert, G Xin. The effects of isolation rearing on glutamate receptor NMDAR1A mRNA expression determined by in situ hybridization in Fawn hooded and Wistar rats. Pharmacology, biochemistry, and behavior. vol 73. issue 1. 2002-12-31. PMID:12076738. |
the precise nature of the neurodevelopmental changes that produce this state are unknown but result in enhanced da neurotransmission in the nucleus accumbens (nac). |
2002-12-31 |
2023-08-12 |
rat |
| Z T Zhu, Y Fu, G Y Hu, G Z Ji. Electrophysiological study on biphasic firing activity elicited by D(1) agonistic-D(2) antagonistic action of (-)-stepholidine in nucleus accumbens. Sheng li xue bao : [Acta physiologica Sinica]. vol 52. issue 2. 2002-12-27. PMID:11961581. |
the firing activities of the nucleus accumbens (nac) neurons were extracellularly recorded with intravenous and iontophoretic administration of the drug in 6-hydroxydopamine (6-ohda)-lesioned and intact rats. |
2002-12-27 |
2023-08-12 |
rat |
| Bin Wang, Fei Luo, Xue-Cai Ge, Ai-Hua Fu, Ji-Sheng Ha. Effects of lesions of various brain areas on drug priming or footshock-induced reactivation of extinguished conditioned place preference. Brain research. vol 950. issue 1-2. 2002-12-23. PMID:12231223. |
through a cpp paradigm (10 sessions of daily pairing of morphine with one of the two compartments), different parts of nucleus accumbens (nac), ventral tegmental area (vta), and central (ce) or lateral (la) nucleus of amygdala were lesioned with a dc current passing through the respective location. |
2002-12-23 |
2023-08-12 |
rat |
| b' C Cohen, G Perrault, C Voltz, R Steinberg, P Soubri\\xc3\\xa. SR141716, a central cannabinoid (CB(1)) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in rats. Behavioural pharmacology. vol 13. issue 5-6. 2002-12-23. PMID:12394421.' |
secondly, using brain microdialysis, sr141716 (1-3 mg/kg) blocked nicotine-induced dopamine release in the shell of the nucleus accumbens (nac) and the bed nucleus of the stria terminalis. |
2002-12-23 |
2023-08-12 |
rat |
| Edwin H Jacobs, Sabine Spijker, Clarine W Verhoog, Konny Kamprath, Taco J de Vries, August B Smit, Anton N M Schoffelmee. Active heroin administration induces specific genomic responses in the nucleus accumbens shell. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 14. 2002-12-19. PMID:12397092. |
long-term drug-induced alterations in gene expression underlying neuroplasticity in the nucleus accumbens (nac) may play a crucial role in relapse behavior in abstinent drug addicts. |
2002-12-19 |
2023-08-12 |
Not clear |
| M M Marcus, A Malmerfelt, S Nyberg, T H Svensso. Biochemical effects in brain of low doses of haloperidol are qualitatively similar to those of high doses. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 5. 2002-11-22. PMID:12208555. |
typical apd increase dopamine output preferentially in the core and atypical apd increase dopamine output preferentially in the shell of the nucleus accumbens (nac). |
2002-11-22 |
2023-08-12 |
rat |
| Joshua M Gulley, Suzanne Doolen, Nancy R Zahnise. Brief, repeated exposure to substrates down-regulates dopamine transporter function in Xenopus oocytes in vitro and rat dorsal striatum in vivo. Journal of neurochemistry. vol 83. issue 2. 2002-11-20. PMID:12423250. |
high-speed chronoamperometry was used to measure clearance of exogenously applied da in dorsal striatum (str) and nucleus accumbens (nac) of anesthetized rats. |
2002-11-20 |
2023-08-12 |
human |
| Christian P Müller, Maria A De Souza Silva, Gail DePalma, Carlos Tomaz, Robert J Carey, Joseph P Husto. The selective serotonin(1A)-receptor antagonist WAY 100635 blocks behavioral stimulating effects of cocaine but not ventral striatal dopamine increase. Behavioural brain research. vol 134. issue 1-2. 2002-11-19. PMID:12191821. |
in-vivo microdialysis was used in behaving rats to measure extracellular concentration of da in the nucleus accumbens (nac). |
2002-11-19 |
2023-08-12 |
rat |
| J Nagel, W Haube. Effects of salient environmental stimuli on extracellular adenosine levels in the rat nucleus accumbens measured by in vivo microdialysis. Behavioural brain research. vol 134. issue 1-2. 2002-11-19. PMID:12191835. |
in the nucleus accumbens (nac), the neuromodulator adenosine plays a major role in control of behaviour. |
2002-11-19 |
2023-08-12 |
rat |
| Garret D Stuber, Scott B Evans, Michael S Higgins, Yanping Pu, Dianne P Figlewic. Food restriction modulates amphetamine-conditioned place preference and nucleus accumbens dopamine release in the rat. Synapse (New York, N.Y.). vol 46. issue 2. 2002-11-19. PMID:12211086. |
to evaluate whether an alteration in extracellular fluid da levels in the nucleus accumbens (nac) core could account for these behavioral alterations, da release was measured by microdialysis. |
2002-11-19 |
2023-08-12 |
rat |
| Stefania Bonaccorso, Herbert Y Meltzer, Zhu Li, Jin Dai, Anna R Alboszta, Junji Ichikaw. SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225700. |
the present study demonstrated that another putative apd and 5-ht(2a/2c) antagonist, sr46349-b (10 mg/kg, but not 1-3 mg/kg) alone, but not m100907 (0.1 and 3 mg/kg) alone, increased mpfc da release, whereas neither drug alone affected nucleus accumbens (nac) da release. |
2002-11-15 |
2023-08-12 |
rat |
| Stefania Bonaccorso, Herbert Y Meltzer, Zhu Li, Jin Dai, Anna R Alboszta, Junji Ichikaw. SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225700. |
neither sr46349-b nor m100907 alone affected nucleus accumbens (nac) da release. |
2002-11-15 |
2023-08-12 |
rat |
| Stefania Bonaccorso, Herbert Y Meltzer, Zhu Li, Jin Dai, Anna R Alboszta, Junji Ichikaw. SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225700. |
neither sr46349-b nor m100907 alone affected nucleus accumbens (nac) da release. |
2002-11-15 |
2023-08-12 |
rat |
| G B Bishop, W E Cullinan, E Curran, H B Gutstei. Abused drugs modulate RGS4 mRNA levels in rat brain: comparison between acute drug treatment and a drug challenge after chronic treatment. Neurobiology of disease. vol 10. issue 3. 2002-11-15. PMID:12270694. |
increases in rgs 4 mrna levels were observed in the nucleus accumbens (nac) and dorsal central gray (cgd). |
2002-11-15 |
2023-08-12 |
rat |
| Donald C Coope. The significance of action potential bursting in the brain reward circuit. Neurochemistry international. vol 41. issue 5. 2002-11-14. PMID:12176075. |
these components include the prefrontal cortex (pfc), amygdala (amy), nucleus accumbens (nac), subiculum (sub) of the hippocampal formation, and the dopamine (da) neurons in the ventral tegmental area (vta). |
2002-11-14 |
2023-08-12 |
Not clear |
| Jean-François Liégeois, Junji Ichikawa, Herbert Y Meltze. 5-HT(2A) receptor antagonism potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and inhibits that in the nucleus accumbens in a dose-dependent manner. Brain research. vol 947. issue 2. 2002-10-30. PMID:12176156. |
we provide additional support for this hypothesis by examining the effect of the selective 5-ht(2a) antagonist m100907 plus haloperidol, a potent d(2) antagonist apd, on da release in the mpfc and nucleus accumbens (nac). |
2002-10-30 |
2023-08-12 |
rat |
| J Neddens, J Lesting, R R Dawirs, G Teuchert-Nood. An early methamphetamine challenge suppresses the maturation of dopamine fibres in the nucleus accumbens of gerbils: on the significance of rearing conditions. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 2. 2002-10-16. PMID:12075854. |
the effect of a single early methamphetamine (ma) challenge on postnatal maturation of the nucleus accumbens (nac) was studied. |
2002-10-16 |
2023-08-12 |
Not clear |
| Karel Pacak, Olga Tjurmina, Milkós Palkovits, David S Goldstein, Christian A Koch, Thomas Hoff, George P Chrouso. Chronic hypercortisolemia inhibits dopamine synthesis and turnover in the nucleus accumbens: an in vivo microdialysis study. Neuroendocrinology. vol 76. issue 3. 2002-10-09. PMID:12218347. |
in this study, we investigated whether hypercortisolemia affects indices of daergic activity in the nucleus accumbens (nac) and the prefrontal cortex (pfc) of freely moving rats. |
2002-10-09 |
2023-08-12 |
rat |