All Relations between nac and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Michael F Salvatore, Subbu Apparsundaram, Greg A Gerhard. Decreased plasma membrane expression of striatal dopamine transporter in aging. Neurobiology of aging. vol 24. issue 8. 2004-03-11. PMID:14643386. using western blot techniques, we investigated whether the source of these age-related changes in dat was correlated with decreases in dat protein levels in the striatum, substantia nigra (sn), nucleus accumbens (nac), and ventral tegmental area (vta) of 6, 18, and 24-month-old male fischer 344 rats. 2004-03-11 2023-08-12 rat
Eliyahu Dremencov, Iris Gispan-Herman, Merav Rosenstein, Avivit Mendelman, David H Overstreet, Joseph Zohar, Gal Yadi. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 1. 2004-02-18. PMID:14687868. because of the central role of accumbal dopamine in the mediation of motivation and reward, our measurements were focused on dopaminergic neurotransmission in the nucleus accumbens (nac). 2004-02-18 2023-08-12 rat
Rossella Ventura, Antonio Alcaro, Simona Cabib, Davide Conversi, Laura Mandolesi, Stefano Puglisi-Allegr. Dopamine in the medial prefrontal cortex controls genotype-dependent effects of amphetamine on mesoaccumbens dopamine release and locomotion. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 1. 2004-02-17. PMID:12968132. in view of the important role of dopamine (da) release in the nucleus accumbens (nac) regarding the behavioral effects of psychostimulants, we tested the hypothesis of an inverse relationship between mesocortical and mesoaccumbens da functioning in the two backgrounds. 2004-02-17 2023-08-12 mouse
David Robbe, Gerard Alonso, Oliver J Manzon. Exogenous and endogenous cannabinoids control synaptic transmission in mice nucleus accumbens. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684448. excitatory transmission to the nucleus accumbens (nac) is involved in the actions of most drugs of abuse, including cannabis. 2004-02-13 2023-08-12 mouse
Marina E Wolf, Simona Mangiavacchi, Xiu Su. Mechanisms by which dopamine receptors may influence synaptic plasticity. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684450. postnatal rat nucleus accumbens (nac) cultures were used to study d1 receptor regulation of the ampa receptor subunit glur1. 2004-02-13 2023-08-12 rat
Carolina Demarchi Munhoz, Isaias Glezer, Elisa Mitiko Kawamoto, Ana Paula Natalini Araújo, Lucília B Lepscha, Cleopatra S Planeta, Roberto DeLucia, Cristoforo Scavon. Changes in sodium, potassium-ATPase induced by repeated fencamfamine: the roles of cyclic AMP-dependent protein kinase and the nitric oxide-cyclic GMP pathway. Neuropharmacology. vol 45. issue 8. 2004-02-11. PMID:14614957. in the present study, we investigate changes in na,k-atpase, cyclic amp-dependent protein kinase (pka) and nitric oxide synthase (nos) activity and cyclic gmp levels in the nucleus accumbens (nac) and striatum (st) of animals acutely or repeatedly treated with fcf (3.5 mg/kg). 2004-02-11 2023-08-12 Not clear
Joshua M Gulley, Brian R Hoover, Gaynor A Larson, Nancy R Zahnise. Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12902997. in rats classified as lcrs or hcrs after 10 mg/kg cocaine injection, we found no differences in (1) novelty-induced locomotion, (2) cocaine levels in dorsal striatum or nucleus accumbens (nac), (3) dat number or affinity in nac, or (4) dat affinity for cocaine in nac. 2004-02-10 2023-08-12 rat
Eagle Y-K Huang, Te-Chen Liu, Pao-Luh Ta. Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine releases at the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 368. issue 5. 2004-02-10. PMID:14564449. by employing the microdialysis technique in free-moving animals, we also determined the extracellular level of dopamine and serotonin metabolites in the shell region of the nucleus accumbens (nac) in its response to morphine with/without dm. 2004-02-10 2023-08-12 Not clear
Edwin H Jacobs, Taco J de Vries, August B Smit, Anton N M Schoffelmee. Gene transcripts selectively down-regulated in the shell of the nucleus accumbens long after heroin self-administration are up-regulated in the core independent of response contingency. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 1. 2004-02-09. PMID:14597559. long-term drug-induced alterations in neurotransmission within the nucleus accumbens (nac) shell and core may underlie relapse to drug-seeking behavior and drug-taking upon re-exposure to drugs and drug-associated stimuli (cues) during abstinence. 2004-02-09 2023-08-12 rat
M J Cano-Cebrián, T Zornoza-Sabina, C Guerri, A Polache, L Graner. Acamprosate blocks the increase in dopamine extracellular levels in nucleus accumbens evoked by chemical stimulation of the ventral hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. vol 368. issue 4. 2004-02-06. PMID:13680089. recently, we have shown that acamprosate is able to modulate extracellular dopamine (da) levels in the nucleus accumbens (nac) and may act as an antagonist of n-methyl-d-aspartate (nmda) receptors. 2004-02-06 2023-08-12 rat
Ezio Carboni, Alessandra Silvagni, Valentina Valentini, Gaetano Di Chiar. Effect of amphetamine, cocaine and depolarization by high potassium on extracellular dopamine in the nucleus accumbens shell of SHR rats. An in vivo microdyalisis study. Neuroscience and biobehavioral reviews. vol 27. issue 7. 2004-01-15. PMID:14624809. because dopamine has been implicated in adhd we studied by in vivo microdialysis the dopamine output in the nucleus accumbens (nac) shell of 6 week-old (pre-hypertensive stage) shr rats and in their normotensive age matched wistar kyoto controls (wky). 2004-01-15 2023-08-12 human
Yong Li, Julie A Kaue. Repeated exposure to amphetamine disrupts dopaminergic modulation of excitatory synaptic plasticity and neurotransmission in nucleus accumbens. Synapse (New York, N.Y.). vol 51. issue 1. 2004-01-12. PMID:14579420. the nucleus accumbens (nac) is a major terminal field of the mesolimbic dopamine neurons and modifications in neuronal structure and function in nac accompany repeated exposure to psychomotor stimulants and other addictive drugs. 2004-01-12 2023-08-12 Not clear
Sarah F Leibowitz, Nicole M Avena, Guo-Qing Chang, Olga Karatayev, David T Chau, Bartley G Hoebe. Ethanol intake increases galanin mRNA in the hypothalamus and withdrawal decreases it. Physiology & behavior. vol 79. issue 1. 2004-01-09. PMID:12818715. earlier studies showed that hypothalamic injection of the feeding-stimulatory peptide, galanin (gal), increases the release of dopamine (da) in the nucleus accumbens (nac), as does systemic alcohol, leading to a focus on gal. 2004-01-09 2023-08-12 rat
Xilu Jiao, William P Paré, Shanaz Tejani-But. Strain differences in the distribution of dopamine transporter sites in rat brain. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 6. 2004-01-05. PMID:14499307. while the binding of [3h]-gbr to dat sites was significantly decreased in the nucleus accumbens (nac), the amygdala, the ventral tegmental area (vta), and the reticular part of the substantia nigra (p<.05), the binding was significantly increased in the hippocampal subregions and the hypothalamus (p<.05) in wky rats compared to the other two strains. 2004-01-05 2023-08-12 rat
Stéphanie Caillé, Marta Rodriguez-Arias, Jose Minarro, Emilio F Espejo, Martine Cador, Luis Stinu. Changes in dopaminergic neurotransmission do not alter somatic or motivational opiate withdrawal-induced symptoms in rats. Behavioral neuroscience. vol 117. issue 5. 2004-01-05. PMID:14570549. opiate withdrawal has been correlated with decreased extracellular dopamine (da) levels in the nucleus accumbens (nac) of morphine-dependent rats. 2004-01-05 2023-08-12 rat
Vladimir I Chefer, Brigitte L Kieffer, Toni S Shippenber. Basal and morphine-evoked dopaminergic neurotransmission in the nucleus accumbens of MOR- and DOR-knockout mice. The European journal of neuroscience. vol 18. issue 7. 2003-12-19. PMID:14622224. conventional and no net flux microdialysis were used to quantify basal and morphine-induced extracellular dopamine (da) levels and the basal extraction fraction, which provides an estimate of the rate of da uptake, in the nucleus accumbens (nac) of wild-type mice and those with a constitutive deletion of mu (mor)- or delta (dor)-opioid receptors. 2003-12-19 2023-08-12 mouse
Michael H Joseph, Krishna Datla, Andrew M J Youn. The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis: the kick, the craving or the cognition? Neuroscience and biobehavioral reviews. vol 27. issue 6. 2003-12-18. PMID:14599434. psychopharmacological studies have implicated the dopaminergic innervation of the nucleus accumbens (nac) in reward and reinforcement, in the actions of addictive drugs, and in the control of the symptoms of schizophrenia. 2003-12-18 2023-08-12 rat
Anthony G Phillips, Soyon Ahn, John G Howlan. Amygdalar control of the mesocorticolimbic dopamine system: parallel pathways to motivated behavior. Neuroscience and biobehavioral reviews. vol 27. issue 6. 2003-12-18. PMID:14599435. the present review focuses on recent findings from our laboratory showing that there are major differences in the influence exerted by the central (cen) and basolateral (bla) nuclei of the amygdala on dopamine (da) efflux in the nucleus accumbens (nac) of the rat. 2003-12-18 2023-08-12 rat
Carrie L Walters, Yuo-Chen Kuo, Julie A Blend. Differential distribution of CREB in the mesolimbic dopamine reward pathway. Journal of neurochemistry. vol 87. issue 5. 2003-12-18. PMID:14622103. to investigate the complex nature of creb function in addiction, we examined the distribution of creb protein in the nucleus accumbens (nac) and ventral tegmental area (vta), two brain regions that are part of the well-defined mesolimbic dopamine pathway involved in reward processing. 2003-12-18 2023-08-12 mouse
Pornnarin Taepavarapruk, Anthony G Phillip. Neurochemical correlates of relapse to d-amphetamine self-administration by rats induced by stimulation of the ventral subiculum. Psychopharmacology. vol 168. issue 1-2. 2003-11-18. PMID:12655460. dynamic changes in extracellular levels of dopamine (da) and metabolites in the nucleus accumbens (nac) during 48-h unlimited access to d-amph by rats were monitored. 2003-11-18 2023-08-12 rat