| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L L Peoples, A V Kravitz, K Guille. The role of accumbal hypoactivity in cocaine addiction. TheScientificWorldJournal. vol 7. 2007-12-06. PMID:17982574. |
cocaine-induced hypoactivity of the nucleus accumbens (nac) is hypothesized to contribute to cocaine addiction. |
2007-12-06 |
2023-08-12 |
Not clear |
| José Antonio Fuentealba, Katia Gysling, María Estela André. Increased locomotor response to amphetamine induced by the repeated administration of the selective kappa-opioid receptor agonist U-69593. Synapse (New York, N.Y.). vol 61. issue 9. 2007-11-29. PMID:17568430. |
acute administration of kappa opioid receptor (kor) agonists decreases both dopamine (da) extracellular levels in the nucleus accumbens (nac) and locomotor activity. |
2007-11-29 |
2023-08-12 |
rat |
| Kenneth D Car. Chronic food restriction: enhancing effects on drug reward and striatal cell signaling. Physiology & behavior. vol 91. issue 5. 2007-11-28. PMID:17081571. |
of particular interest is an upregulation of nmda receptor-dependent map kinase and cam kinase ii signaling, creb phosphorylation, and immediate-early and neuropeptide gene expression in nucleus accumbens (nac) which may facilitate reward-related learning, but also play a role in the genesis of maladaptive goal-directed behaviors. |
2007-11-28 |
2023-08-12 |
rat |
| Alexandra Jean, Grégory Conductier, Christine Manrique, Constantin Bouras, Philippe Berta, René Hen, Yves Charnay, Joël Bockaert, Valérie Compa. Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 41. 2007-11-28. PMID:17913892. |
we hypothesized that anorexia may involve altered signaling events within the nucleus accumbens (nac), a brain structure involved in reward. |
2007-11-28 |
2023-08-12 |
mouse |
| Danielle L Graham, Scott Edwards, Ryan K Bachtell, Ralph J DiLeone, Maribel Rios, David W Sel. Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. Nature neuroscience. vol 10. issue 8. 2007-11-07. PMID:17618281. |
we found that 4 h of intravenous cocaine self-administration in rats induced a transient increase in brain-derived neurotrophic factor (bdnf) and activation of trkb-mediated signaling in the nucleus accumbens (nac). |
2007-11-07 |
2023-08-12 |
mouse |
| M A De Luca, V Bassareo, A Bauer, G Di Chiar. Caffeine and accumbens shell dopamine. Journal of neurochemistry. vol 103. issue 1. 2007-11-07. PMID:17655660. |
as well as specific a1 (dpcpx, 8-cyclopentyl-1,3-dipropylxanthine) receptor antagonists fail to increase extracellular dopamine (da) in the shell of the nucleus accumbens (nac). |
2007-11-07 |
2023-08-12 |
rat |
| Amy C Boudreau, Jeremy M Reimers, Michael Milovanovic, Marina E Wol. Cell surface AMPA receptors in the rat nucleus accumbens increase during cocaine withdrawal but internalize after cocaine challenge in association with altered activation of mitogen-activated protein kinases. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 39. 2007-11-07. PMID:17898233. |
although some studies report increased responsiveness of nucleus accumbens (nac) ampa receptors (ampars) after withdrawal from repeated cocaine treatment, others report decreased responsiveness after withdrawal plus cocaine challenge. |
2007-11-07 |
2023-08-12 |
rat |
| Hiroyuki Mizoguchi, Kiyofumi Yamada, Akihiro Mouri, Minae Niwa, Tomoko Mizuno, Yukihiro Noda, Atsumi Nitta, Shigeyoshi Itohara, Yoshiko Banno, Toshitaka Nabeshim. Role of matrix metalloproteinase and tissue inhibitor of MMP in methamphetamine-induced behavioral sensitization and reward: implications for dopamine receptor down-regulation and dopamine release. Journal of neurochemistry. vol 102. issue 5. 2007-11-06. PMID:17472698. |
antisense timp-2 oligonucleotide (timp-as) treatment enhanced the sensitization, which was associated with the potentiation of meth-induced dopamine release in the nucleus accumbens (nac). |
2007-11-06 |
2023-08-12 |
mouse |
| Xiu-Ti H. Cocaine withdrawal and neuro-adaptations in ion channel function. Molecular neurobiology. vol 35. issue 1. 2007-10-23. PMID:17519508. |
chronic exposure to psychostimulants induces neuro-adaptations in ion channel function of dopamine (da)-innervated cells localized within the medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2007-10-23 |
2023-08-12 |
human |
| Ying-xia Gong, Hui-juan Wang, Yong-ping Zhu, Wei-ping Zhang, Hai-bing Dai, Shi-hong Zhang, Er-qing Wei, Zhong Che. Carnosine ameliorates morphine-induced conditioned place preference in rats. Neuroscience letters. vol 422. issue 1. 2007-09-26. PMID:17590512. |
although carnosine had no appreciable effect on the levels of histamine in the ventral tegmental area (vta), nucleus accumbens (nac) and prefrontal cortex (pfc), it significantly decreased glutamate level in the vta, dopamine levels in the nac and pfc, and dopac level in the nac of morphine-treated rats. |
2007-09-26 |
2023-08-12 |
rat |
| Matthias E Liechti, Loic Lhuillier, Klemens Kaupmann, Athina Marko. Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 34. 2007-09-11. PMID:17715344. |
metabotropic glutamate (mglu) 2/3 receptors regulate glutamate and dopamine release in the ventral tegmental area (vta) and the nucleus accumbens (nac) shell, two brain areas critically involved in reward and motivational processes. |
2007-09-11 |
2023-08-12 |
rat |
| Shamseddin Ahmadi, Mohammad Reza Zarrindast, Ali Haeri-Rohani, Ameneh Rezayof, Maryam Nour. Nicotine improves morphine-induced impairment of memory: possible involvement of N-methyl-D-aspartate receptors in the nucleus accumbens. Developmental neurobiology. vol 67. issue 8. 2007-09-06. PMID:17565710. |
the possible involvement of n-methyl-d-aspartate (nmda) receptors in the nucleus accumbens (nac) in nicotine's effect on impairment of memory by morphine was investigated. |
2007-09-06 |
2023-08-12 |
rat |
| David J Scott, Christian S Stohler, Christine M Egnatuk, Heng Wang, Robert A Koeppe, Jon-Kar Zubiet. Individual differences in reward responding explain placebo-induced expectations and effects. Neuron. vol 55. issue 2. 2007-08-29. PMID:17640532. |
using healthy human subjects, we examined the role of the nucleus accumbens (nac), a region centrally involved in the encoding of reward expectation, in the formation of placebo responses. |
2007-08-29 |
2023-08-12 |
human |
| Graham A Cousens, Jacob T Beckle. Antagonism of nucleus accumbens M(2) muscarinic receptors disrupts operant responding for sucrose under a progressive ratio reinforcement schedule. Behavioural brain research. vol 181. issue 1. 2007-08-24. PMID:17499370. |
non-selective machr blockade within the nucleus accumbens (nac) has been shown to disrupt operant responding for food and to inhibit food consumption. |
2007-08-24 |
2023-08-12 |
Not clear |
| Saïd Kourrich, Patrick E Rothwell, Jason R Klug, Mark J Thoma. Cocaine experience controls bidirectional synaptic plasticity in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 30. 2007-08-20. PMID:17652583. |
in animal models of addiction, glutamatergic signaling in the nucleus accumbens (nac) exerts powerful control over drug-seeking behavior. |
2007-08-20 |
2023-08-12 |
mouse |
| Minae Niwa, Atsumi Nitta, Hiroyuki Mizoguchi, Yasutomo Ito, Yukihiro Noda, Taku Nagai, Toshitaka Nabeshim. A novel molecule "shati" is involved in methamphetamine-induced hyperlocomotion, sensitization, and conditioned place preference. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 28. 2007-08-07. PMID:17626222. |
in the present study, we have identified a novel molecule "shati" from the nucleus accumbens (nac) of mice treated with methamphetamine (meth) using the pcr-select complementary dna subtraction method. |
2007-08-07 |
2023-08-12 |
mouse |
| Mina Ito, Taku Nagai, Hiroyuki Mizoguchi, Ayumi Fukakusa, Yutaka Nakanishi, Hiroyuki Kamei, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamad. Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system. Journal of neurochemistry. vol 101. issue 5. 2007-08-06. PMID:17286591. |
we have previously demonstrated that tissue plasminogen activator (tpa)-plasmin system participates in the rewarding effect of morphine, by regulating dopamine release in the nucleus accumbens (nac). |
2007-08-06 |
2023-08-12 |
mouse |
| Hiromi Sano, Mineto Yoko. Striatal medium spiny neurons terminate in a distinct region in the lateral hypothalamic area and do not directly innervate orexin/hypocretin- or melanin-concentrating hormone-containing neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 26. 2007-08-01. PMID:17596443. |
neuronal circuits including medium spiny neurons (msns) in the nucleus accumbens (nac) and melanin-concentrating hormone (mch)-containing neurons in the lateral hypothalamic area (lha) are hypothesized to play an important role in hedonic feeding. |
2007-08-01 |
2023-08-12 |
Not clear |
| Hui-Fen Liu, Wen-Hua Zhou, Hua-Qiang Zhu, Miao-Jun Lai, Wei-Sheng Che. Microinjection of M(5) muscarinic receptor antisense oligonucleotide into VTA inhibits FosB expression in the NAc and the hippocampus of heroin sensitized rats. Neuroscience bulletin. vol 23. issue 1. 2007-07-31. PMID:17592519. |
to investigate the effect of m(5) muscarinic receptor subtype on the locomotor sensitization induced by heroin priming, and it's effect on the fosb expression in the nucleus accumbens (nac) and the hippocampus in the heroin sensitized rats. |
2007-07-31 |
2023-08-12 |
rat |
| Elio Acquas, Augusta Pisanu, Saturnino Spiga, Antonio Plumitallo, Gerald Zernig, Gaetano Di Chiar. Differential effects of intravenous R,S-(+/-)-3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its S(+)- and R(-)-enantiomers on dopamine transmission and extracellular signal regulated kinase phosphorylation (pERK) in the rat nucleus accumbens shell and core. Journal of neurochemistry. vol 102. issue 1. 2007-07-30. PMID:17564678. |
r,s(+/-)-3,4-methylenedioxymethamphetamine (r,s(+/-)-mdma, 'ecstasy') is known to stimulate dopamine (da) transmission in the nucleus accumbens (nac). |
2007-07-30 |
2023-08-12 |
rat |