| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zuzana Kapasova, Karen K Szumlinsk. Strain differences in alcohol-induced neurochemical plasticity: a role for accumbens glutamate in alcohol intake. Alcoholism, clinical and experimental research. vol 32. issue 4. 2008-06-02. PMID:18341649. |
repeated alcohol administration alters nucleus accumbens (nac) basal glutamate content and sensitizes the capacity of alcohol to increase nac extracellular glutamate levels. |
2008-06-02 |
2023-08-12 |
Not clear |
| Taku Nagai, Kazuhiro Takuma, Toshitaka Nabeshima, Kiyofumi Yamad. [Regulation by tissue plasminogen activator of rewarding effects of drugs of abuse]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 28. issue 1. 2008-05-30. PMID:18411702. |
drugs of abuse acutely modulate the activity of mesolimbic dopaminergic neurons, projecting from the ventral tegmental area of the midbrain to the nucleus accumbens (nac). |
2008-05-30 |
2023-08-12 |
mouse |
| Fay A Guarraci, Russell J Frohardt, Debra Hines, Erica Navaira, Julie Smith, Lawrence Wample. Intracranial infusions of amphetamine into the medial preoptic area but not the nucleus accumbens affect paced mating behavior in female rats. Pharmacology, biochemistry, and behavior. vol 89. issue 3. 2008-05-20. PMID:18261786. |
in experiments 2 and 3, amph (0.5 microl of 40 microg/microl) or vehicle was infused bilaterally into the shell region of the nucleus accumbens (nac) or core region of the nac, respectively. |
2008-05-20 |
2023-08-12 |
rat |
| Ayumi Fukakusa, Taku Nagai, Hiroyuki Mizoguchi, Noboru Otsuka, Haruhide Kimura, Hiroyuki Kamei, Hyoung-Chun Kim, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamad. Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens. Journal of neurochemistry. vol 105. issue 2. 2008-05-06. PMID:18036193. |
in this study, we investigated whether the tpa-plasmin system is involved in the development of sensitization in meth-induced dopamine release in the nucleus accumbens (nac). |
2008-05-06 |
2023-08-12 |
mouse |
| Khalid Touzani, Richard Bodnar, Anthony Sclafan. Activation of dopamine D1-like receptors in nucleus accumbens is critical for the acquisition, but not the expression, of nutrient-conditioned flavor preferences in rats. The European journal of neuroscience. vol 27. issue 6. 2008-05-05. PMID:18336564. |
the present study investigated the role of dopamine neurotransmission within the nucleus accumbens (nac) in flavor preference learning induced by the postoral consequences of carbohydrates. |
2008-05-05 |
2023-08-12 |
rat |
| Xiu Sun, Michael Milovanovic, Yun Zhao, Marina E Wol. Acute and chronic dopamine receptor stimulation modulates AMPA receptor trafficking in nucleus accumbens neurons cocultured with prefrontal cortex neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 16. 2008-05-05. PMID:18417701. |
postsynaptic interactions between dopamine (da) and glutamate receptors in the nucleus accumbens (nac) are critical for addiction. |
2008-05-05 |
2023-08-12 |
mouse |
| Anupom Borah, Kochupurackal P Mohanakuma. Long-term L-DOPA treatment causes indiscriminate increase in dopamine levels at the cost of serotonin synthesis in discrete brain regions of rats. Cellular and molecular neurobiology. vol 27. issue 8. 2008-05-01. PMID:17934805. |
l-dopa, norepinephrine, 5-ht, 5-hydroxyindoleacetic acid (5-hiaa), dopamine, homovanillic acid (hva), and 3,4-dihydroxyphenylacetic acid (dopac) were measured in striatum, nucleus raphe dorsalis (nrd), nucleus accumbens (nac), substantia nigra, cerebellum, and cortex employing hplc-electrochemical procedure. |
2008-05-01 |
2023-08-12 |
rat |
| Christopher M Olsen, Yong Huang, Shirlean Goodwin, Daniel C Ciobanu, Lu Lu, Thomas R Sutter, Danny G Winde. Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum. Physiological genomics. vol 32. issue 3. 2008-04-28. PMID:17911379. |
to identify distinct transcriptional patterns between the major subcortical dopamine targets commonly studied in addiction we studied differences in gene expression between the bed nucleus of the stria terminalis (bnst), nucleus accumbens (nac), and dorsal striatum (dstr) using microarray analysis. |
2008-04-28 |
2023-08-12 |
Not clear |
| O Malkesman, Y Braw, E Ram, R Maayan, A Weizman, N Kinor, G Yadid, A Welle. Dehydroepiandrosterone and monoamines in the limbic system of a genetic animal model of childhood depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 4. 2008-04-23. PMID:17714920. |
monoamines and dehydroepiandrosterone (dhea) levels were measured in a genetic animal model for childhood depression in four subcortical structures: nucleus accumbens (nac), ventral tegmental area (vta), amygdala and hypothalamus. |
2008-04-23 |
2023-08-12 |
rat |
| BomBi Lee, Chae Ha Yang, Dae-Hyun Hahm, Hye-Jung Lee, Seung-Moo Han, Kyung-Soo Kim, Insop Shi. Inhibitory effects of ginseng total saponins on behavioral sensitization and dopamine release induced by cocaine. Biological & pharmaceutical bulletin. vol 31. issue 3. 2008-04-21. PMID:18310906. |
it has been shown that repeated injections of cocaine produce an increase in locomotor activity, the expression of the immediate-early gene, c-fos, and the release of dopamine (da) in the nucleus accumbens (nac), which is one of the main dopaminergic terminal areas. |
2008-04-21 |
2023-08-12 |
rat |
| X Cen, A Nitta, D Ibi, Y Zhao, M Niwa, K Taguchi, M Hamada, Y Ito, Y Ito, L Wang, T Nabeshim. Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization. Molecular psychiatry. vol 13. issue 4. 2008-04-17. PMID:18195717. |
we found that piccolo, a presynaptic scaffolding protein, was overexpressed in the nucleus accumbens (nac) of the mice repeatedly administrated with meth. |
2008-04-17 |
2023-08-12 |
mouse |
| K Sano, K Mishima, E Koushi, K Orito, N Egashira, K Irie, K Takasaki, S Katsurabayashi, K Iwasaki, N Uchida, T Egawa, Y Kitamura, R Nishimura, M Fujiwar. Delta 9-tetrahydrocannabinol-induced catalepsy-like immobilization is mediated by decreased 5-HT neurotransmission in the nucleus accumbens due to the action of glutamate-containing neurons. Neuroscience. vol 151. issue 2. 2008-04-15. PMID:18083311. |
moreover, thc-induced catalepsy was abolished by lesions in the nucleus accumbens (nac) and central amygdala (ace) regions. |
2008-04-15 |
2023-08-12 |
rat |
| Hong-Yu Liu, Jie Jin, Jing-Shi Tang, Wei-Xin Sun, Hong Jia, Xin-Ping Yang, Jian-Mei Cui, Chen-Guang Wan. Chronic deep brain stimulation in the rat nucleus accumbens and its effect on morphine reinforcement. Addiction biology. vol 13. issue 1. 2008-04-14. PMID:18269379. |
in order to explore a novel method for the treatment of drug abuse, we evaluated the effect of chronic deep brain stimulation (dbs) of the rat nucleus accumbens (nac) on morphine reinforcement, using a dbs apparatus and an implant method we developed. |
2008-04-14 |
2023-08-12 |
rat |
| M A de Souza Silva, B Topic, J P Huston, C Matter. Intranasal dopamine application increases dopaminergic activity in the neostriatum and nucleus accumbens and enhances motor activity in the open field. Synapse (New York, N.Y.). vol 62. issue 3. 2008-04-11. PMID:18081176. |
rats previously implanted with guide-cannulae in the neostriatum (ns) and nucleus accumbens (nac) were submitted to microdialysis procedure under urethane anesthesia. |
2008-04-11 |
2023-08-12 |
rat |
| Joshua L Jones, Robert A Wheeler, Regina M Carell. Behavioral responding and nucleus accumbens cell firing are unaltered following periods of abstinence from sucrose. Synapse (New York, N.Y.). vol 62. issue 3. 2008-04-11. PMID:18088061. |
here, we examined whether abstinence from sucrose self-administration in rats altered behavioral responding and nucleus accumbens (nac) cell firing in a manner similar to that observed following cocaine abstinence. |
2008-04-11 |
2023-08-12 |
rat |
| Alexis W Ary, Karen Kathleen Szumlinsk. Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: a two-species comparison. Brain research. vol 1184. 2008-04-08. PMID:17950706. |
in both species, withdrawal from repeated cocaine administration down-regulated homer1b/c and homer2a/b within the shell, but not the core, of the nucleus accumbens (nac), and the reduced homer levels were accompanied by decreases in mglur1a, nr2a and nr2b. |
2008-04-08 |
2023-08-12 |
mouse |
| Robert A Wheeler, Robert C Twining, Joshua L Jones, Jennifer M Slater, Patricia S Grigson, Regina M Carell. Behavioral and electrophysiological indices of negative affect predict cocaine self-administration. Neuron. vol 57. issue 5. 2008-04-08. PMID:18341996. |
the expression of aversive taste reactivity also was associated with a shift in the predominant pattern of electrophysiological activity of nucleus accumbens (nac) neurons from inhibitory to excitatory. |
2008-04-08 |
2023-08-12 |
rat |
| Yanhua H Huang, Ying Lin, Travis E Brown, Ming-Hu Han, Daniel B Saal, Rachael L Neve, R Suzanne Zukin, Barbara A Sorg, Eric J Nestler, Robert C Malenka, Yan Don. CREB modulates the functional output of nucleus accumbens neurons: a critical role of N-methyl-D-aspartate glutamate receptor (NMDAR) receptors. The Journal of biological chemistry. vol 283. issue 5. 2008-04-02. PMID:18055458. |
nucleus accumbens (nac) medium spiny neurons cycle between two states, a functionally inactive downstate and a functionally active upstate. |
2008-04-02 |
2023-08-12 |
Not clear |
| Hiroyuki Mizoguchi, Kiyofumi Yamada, Toshitaka Nabeshim. Neuropsychotoxicity of abused drugs: involvement of matrix metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-2 in methamphetamine-induced behavioral sensitization and reward in rodents. Journal of pharmacological sciences. vol 106. issue 1. 2008-03-04. PMID:18198472. |
an antisense timp-2 oligonucleotide enhanced the sensitization, which was associated with a potentiation of the meth-induced release of dopamine in the nucleus accumbens (nac). |
2008-03-04 |
2023-08-12 |
mouse |
| Takayuki Nakagawa, Shuji Kanek. Neuropsychotoxicity of abused drugs: molecular and neural mechanisms of neuropsychotoxicity induced by methamphetamine, 3,4-methylenedioxymethamphetamine (ecstasy), and 5-methoxy-N,N-diisopropyltryptamine (foxy). Journal of pharmacological sciences. vol 106. issue 1. 2008-03-04. PMID:18198474. |
several lines of evidence suggest that their chronic treatment leads to the enhancement of the mesocorticolimbic dopaminergic neurons from the ventral tegmental area (vta) to the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc) and leads to abnormal glutamatergic function from the mpfc to the nac and vta. |
2008-03-04 |
2023-08-12 |
xenopus_laevis |