| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Camron D Bryant, Melissa E Graham, Margaret G Distler, Michaelanne B Munoz, Dongdong Li, Paul Vezina, Greta Sokoloff, Abraham A Palme. A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine. Psychopharmacology. vol 203. issue 4. 2009-08-17. PMID:19050854. |
we previously colocalized a quantitative trait locus (qtl) for sensitivity to the locomotor stimulant effects of methamphetamine (ma) with a qtl for expression of casein kinase 1 epsilon (csnk1-epsilon) in the nucleus accumbens (nac). |
2009-08-17 |
2023-08-12 |
mouse |
| R Pedroza-Llinás, L Ramírez-Lugo, K Guzmán-Ramos, S Zavala-Vega, F Bermúdez-Ratton. Safe taste memory consolidation is disrupted by a protein synthesis inhibitor in the nucleus accumbens shell. Neurobiology of learning and memory. vol 92. issue 1. 2009-08-17. PMID:19249379. |
here we evaluated the effects of the administration of a protein synthesis inhibitor in the nucleus accumbens (nac) shell for either safe or aversive taste memory trace consolidation. |
2009-08-17 |
2023-08-12 |
rat |
| Lifen Zhang, William M Doyon, Jeremy J Clark, Paul E M Phillips, John A Dan. Controls of tonic and phasic dopamine transmission in the dorsal and ventral striatum. Molecular pharmacology. vol 76. issue 2. 2009-08-17. PMID:19460877. |
the ratio of phasic-to-tonic-evoked da signals varied with the average ongoing firing frequency, and the ratio was generally higher in the nucleus accumbens (nac) compared with the dorsolateral striatum. |
2009-08-17 |
2023-08-12 |
Not clear |
| John E Kelsey, Lyle P Gerety, Rejean M Guerrier. Electrolytic lesions of the nucleus accumbens core (but not the medial shell) and the basolateral amygdala enhance context-specific locomotor sensitization to nicotine in rats. Behavioral neuroscience. vol 123. issue 3. 2009-08-13. PMID:19485564. |
we previously demonstrated that lesions of the nucleus accumbens (nac) core enhanced locomotion and locomotor sensitization to repeated injections of nicotine in rats (kelsey & willmore, 2006). |
2009-08-13 |
2023-08-12 |
rat |
| Kenneth D Carr, Soledad Cabeza de Vaca, Yanjie Sun, Lily S Cha. Reward-potentiating effects of D-1 dopamine receptor agonist and AMPAR GluR1 antagonist in nucleus accumbens shell and their modulation by food restriction. Psychopharmacology. vol 202. issue 4. 2009-08-11. PMID:18841347. |
the neuroanatomical site(s) of key neuroadaptations may include nucleus accumbens (nac) where changes in d-1 dopamine (da) receptor-mediated cell signaling and gene expression have been documented. |
2009-08-11 |
2023-08-12 |
Not clear |
| Yanhua H Huang, Ying Lin, Ping Mu, Brian R Lee, Travis E Brown, Gary Wayman, Helene Marie, Wenhua Liu, Zhen Yan, Barbara A Sorg, Oliver M Schlüter, R Suzanne Zukin, Yan Don. In vivo cocaine experience generates silent synapses. Neuron. vol 63. issue 1. 2009-08-11. PMID:19607791. |
here, we demonstrate that highly salient in vivo experience, such as exposure to cocaine, generates silent synapses in the nucleus accumbens (nac) shell, a key brain region mediating addiction-related learning and memory. |
2009-08-11 |
2023-08-12 |
Not clear |
| Marie A Pezze, Jeffrey W Dalley, Trevor W Robbin. Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D(2/3) receptor antagonist sulpiride. Psychopharmacology. vol 202. issue 1-3. 2009-08-05. PMID:18985321. |
the prefrontal cortex (pfc) and nucleus accumbens (nac) are key brain loci considered to mediate many of the cognitive deficits associated with schizophrenia and related disorders. |
2009-08-05 |
2023-08-12 |
rat |
| Elena H Chartoff, Matthew F Barhight, Steve D Mague, Allison M Sawyer, William A Carlezo. Anatomically dissociable effects of dopamine D1 receptor agonists on reward and relief of withdrawal in morphine-dependent rats. Psychopharmacology. vol 204. issue 2. 2009-08-05. PMID:19148621. |
chronic opiate administration induces neuroadaptations within the nucleus accumbens (nac) and ventral tegmental area (vta) that can contribute to dependence. |
2009-08-05 |
2023-08-12 |
rat |
| Xia Li, Jie Li, Xiao-Qing Peng, Krista Spiller, Eliot L Gardner, Zheng-Xiong X. Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 7. 2009-08-03. PMID:19158667. |
microinjections of amn082 (1-5 microg/microl per side) into the nucleus accumbens (nac) or ventral pallidum (vp), but not dorsal striatum, also inhibited cocaine self-administration in a dose-dependent manner. |
2009-08-03 |
2023-08-12 |
rat |
| Matthew R Campioni, Ming Xu, Daniel S McGehe. Stress-induced changes in nucleus accumbens glutamate synaptic plasticity. Journal of neurophysiology. vol 101. issue 6. 2009-08-03. PMID:19357347. |
the nucleus accumbens (nac), a motor-limbic interface linked to motivation and reward, receives inputs from each of these stress-affected brain regions, raising the possibility that its function might also be altered in response to stress. |
2009-08-03 |
2023-08-12 |
mouse |
| Debra K Cozzoli, Scott P Goulding, Ping Wu Zhang, Bo Xiao, Jia-Hua Hu, Alexis W Ary, Ilona Obara, Alison Rahn, Hoda Abou-Ziab, Burgundy Tyrrel, Christina Marini, Naomi Yoneyama, Pamela Metten, Christopher Snelling, Marlin H Dehoff, John C Crabbe, Deborah A Finn, Matthias Klugmann, Paul F Worley, Karen K Szumlinsk. Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 27. 2009-08-03. PMID:19587272. |
the glutamate receptor-associated protein homer2 regulates alcohol-induced neuroplasticity within the nucleus accumbens (nac), but the precise intracellular signaling cascades involved are not known. |
2009-08-03 |
2023-08-12 |
mouse |
| Zheng-xiong Xi, Krista Spiller, Eliot L Gardne. Mechanism-based medication development for the treatment of nicotine dependence. Acta pharmacologica Sinica. vol 30. issue 6. 2009-07-31. PMID:19434058. |
nicotine binds to alpha4beta2 and alpha7 nicotinic acetylcholine receptors (nachrs) located on dopaminergic, glutamatergic and gabaergic neurons in the mesolimbic dopamine (da) system, which causes an increase in extracellular da in the nucleus accumbens (nac). |
2009-07-31 |
2023-08-12 |
Not clear |
| Ke-chun Yang, Guo-zhang Jin, Jie W. Mysterious alpha6-containing nAChRs: function, pharmacology, and pathophysiology. Acta pharmacologica Sinica. vol 30. issue 6. 2009-07-31. PMID:19498417. |
by modulating da release in the nucleus accumbens (nac) and modulating gaba release onto daergic neurons in the ventral tegmental area (vta), alpha6*-nachrs may play important roles in the mediation of nicotine reward and addiction. |
2009-07-31 |
2023-08-12 |
mouse |
| Gero Falkenstein, Christoph Rosenthal, Torsten Reum, Rudolf Morgenstern, Máté Döbrössy, Guido Nikkha. Pattern of long-term sensorimotor recovery following intrastriatal and--accumbens DA micrografts in a rat model of Parkinson's disease. The Journal of comparative neurology. vol 515. issue 1. 2009-07-28. PMID:19399892. |
here we investigated two implantation sites, the nucleus accumbens (nac) and the caudate-putamen unit (cpu), and two different graft distributions within the cpu, i.e., two 0.75 microl deposits (cpu-2) versus six 0.25 microl deposits (cpu-6) in a rat model of pd. |
2009-07-28 |
2023-08-12 |
rat |
| Mahmoud Hosseini, Hojjat Allah Alaei, Rahelah Headari, Mohammad Javad Eslamizade. Effects of microinjection of angiotensin II and captopril into nucleus accumbens on morphine self-administration in rats. Indian journal of experimental biology. vol 47. issue 5. 2009-07-23. PMID:19579802. |
with an aim to investigate the effects of injection of angiotensin ii (ang ii) and captopril into the nucleus accumbens (nac) on morphine self-administration, male wistar rats were first trained to receive small pellets of food by pressing the active lever in self-administration apparatus. |
2009-07-23 |
2023-08-12 |
rat |
| David M Thomas, Dina M Francescutti-Verbeem, Donald M Kuh. Increases in cytoplasmic dopamine compromise the normal resistance of the nucleus accumbens to methamphetamine neurotoxicity. Journal of neurochemistry. vol 109. issue 6. 2009-07-17. PMID:19457119. |
the nucleus accumbens (nac) is largely spared of the damage that accompanies binge meth intoxication. |
2009-07-17 |
2023-08-12 |
Not clear |
| Matthew B Wilkinson, Guanghua Xiao, Arvind Kumar, Quincey LaPlant, William Renthal, Devanjan Sikder, Thomas J Kodadek, Eric J Nestle. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 24. 2009-07-17. PMID:19535594. |
here, we use chromatin immunoprecipitation (chip)-chip assays--chip followed by genome wide promoter array analyses--to study the effects of chronic defeat stress on chromatin regulation in the mouse nucleus accumbens (nac), a key brain reward region implicated in depression. |
2009-07-17 |
2023-08-12 |
mouse |
| Mark E Walton, James Groves, Katie A Jennings, Paula L Croxson, Trevor Sharp, Matthew F S Rushworth, David M Bannerma. Comparing the role of the anterior cingulate cortex and 6-hydroxydopamine nucleus accumbens lesions on operant effort-based decision making. The European journal of neuroscience. vol 29. issue 8. 2009-07-13. PMID:19385990. |
both the anterior cingulate cortex (acc) and mesolimbic dopamine, particularly in the nucleus accumbens (nac), have been implicated in allowing an animal to overcome effort constraints to obtain greater benefits. |
2009-07-13 |
2023-08-12 |
rat |
| Samuel B Kombian, Kethireddy V V Ananthalakshmi, Jeffrey A Zidichouski, Tarek M Sale. Substance P and cocaine employ convergent mechanisms to depress excitatory synaptic transmission in the rat nucleus accumbens in vitro. The European journal of neuroscience. vol 29. issue 8. 2009-07-13. PMID:19385993. |
substance p (sp) has been reported to produce effects on excitatory synaptic transmission in the nucleus accumbens (nac) that are similar to those induced by cocaine. |
2009-07-13 |
2023-08-12 |
rat |
| Francesco Belardetti, Soyon Ahn, Kitty So, Terrance P Snutch, Anthony G Phillip. Block of voltage-gated calcium channels stimulates dopamine efflux in rat mesocorticolimbic system. Neuropharmacology. vol 56. issue 6-7. 2009-07-07. PMID:19371580. |
; 2.5-10 mg/kg) or by reverse-dialysis (10-25 microm) into either the ventral tegmental area (vta) or the nucleus accumbens (nac), and the changes in da levels in both the vta and nac were monitored using microdialysis. |
2009-07-07 |
2023-08-12 |
rat |