| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan-Yuan Hou, Bin Lu, Mu Li, Yao Liu, Jie Chen, Zhi-Qiang Chi, Jing-Gen Li. Involvement of actin rearrangements within the amygdala and the dorsal hippocampus in aversive memories of drug withdrawal in acute morphine-dependent rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 39. 2009-10-13. PMID:19793983. |
we found that lesions of the amygdala or dorsal hippocampus (dh) but not nucleus accumbens (nac) impaired conditioned place aversion (cpa) of acute morphine-dependent rats. |
2009-10-13 |
2023-08-12 |
rat |
| Marcello D'Ascenzo, Maria Vittoria Podda, Tommaso Fellin, Gian Battista Azzena, Philip Haydon, Claudio Grass. Activation of mGluR5 induces spike afterdepolarization and enhanced excitability in medium spiny neurons of the nucleus accumbens by modulating persistent Na+ currents. The Journal of physiology. vol 587. issue Pt 13. 2009-10-09. PMID:19433572. |
the involvement of metabotropic glutamate receptors type 5 (mglur5) in drug-induced behaviours is well-established but limited information is available on their functional roles in addiction-relevant brain areas like the nucleus accumbens (nac). |
2009-10-09 |
2023-08-12 |
Not clear |
| Carmen del Castillo, Lidia Morales, Luis F Alguacil, Elisabet Salas, Elisa Garrido, Elba Alonso, Carmen Pérez-Garcí. Proteomic analysis of the nucleus accumbens of rats with different vulnerability to cocaine addiction. Neuropharmacology. vol 57. issue 1. 2009-10-01. PMID:19393250. |
once the phenotype was established, we compared the protein expression in the nucleus accumbens (nac) of these animals after a single injection of either saline (sal) or cocaine (coc, 15 mg/kg). |
2009-10-01 |
2023-08-12 |
rat |
| John E Kelsey, Ellen J Willmor. Electrolytic lesions of the nucleus accumbens enhance locomotor sensitization to nicotine in rats. Behavioral neuroscience. vol 120. issue 3. 2009-09-30. PMID:16768612. |
electrolytic lesions of the medial core of the nucleus accumbens (nac) in male long-evans rats increased spontaneous locomotion, enhanced the locomotor stimulating effect of acute 5.0 mg/kg cocaine, enhanced the development and subsequent expression of locomotor sensitization produced by repeated injections of 0.4 mg/kg nicotine but not 7.5 mg/kg cocaine, and enhanced the expression of conditioned locomotion. |
2009-09-30 |
2023-08-12 |
rat |
| A Marazioti, C Spyraki, K Thermo. GABA antagonists reverse the somatostatin dependent attenuation of rat locomotor activity. Neuropeptides. vol 43. issue 3. 2009-09-30. PMID:19414189. |
; 120 ng/side nucleus accumbens (nac)) or phaclofen (gaba-b antagonist; 10 mg/kg/ml, i.p. |
2009-09-30 |
2023-08-12 |
rat |
| Adrian Mundt, Julia Klein, Daphna Joel, Andreas Heinz, Anais Djodari-Irani, Daniel Harnack, Andreas Kupsch, Helmut Orawa, Georg Juckel, Rudolf Morgenstern, Christine Winte. High-frequency stimulation of the nucleus accumbens core and shell reduces quinpirole-induced compulsive checking in rats. The European journal of neuroscience. vol 29. issue 12. 2009-09-28. PMID:19490027. |
currently available data on dbs of the nucleus accumbens (nac) on ocd-like behavior in rat models of ocd are contradictory and partly in contrast to clinical data and theoretical hypotheses about how the nac might be pathophysiologically involved in the manifestation of ocd. |
2009-09-28 |
2023-08-12 |
rat |
| Alberto Del Arco, Francisco Mor. Neurotransmitters and prefrontal cortex-limbic system interactions: implications for plasticity and psychiatric disorders. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 8. 2009-09-24. PMID:19475335. |
the pfc sends glutamatergic outputs to limbic areas such as the hippocampus and amygdala which in turn modulate the activity of the nucleus accumbens (nac). |
2009-09-24 |
2023-08-12 |
Not clear |
| Gianluigi Tanda, Amy Hauck Newman, Aaron L Ebbs, Valeria Tronci, Jennifer L Green, Ronald J Tallarida, Jonathan L Kat. Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity. The Journal of pharmacology and experimental therapeutics. vol 330. issue 3. 2009-09-21. PMID:19483071. |
effects of combinations of cocaine with a cocaine analog, 2beta-carbomethoxy-3beta-(4-fluorophenyl)tropane (win 35,428), were compared quantitatively with the combinations of cocaine with the n-butyl,4',4''-dif benztropine analog, 3-(bis(4-fluorophenyl)methoxy)-8-butyl-8-azabicyclo[3.2.1]octane (jhw 007), to determine whether their effects on da levels in the shell of the nucleus accumbens (nac) in mice differed. |
2009-09-21 |
2023-08-12 |
mouse |
| Dinah L Ramos-Ortolaza, Alejandro Negrón, Daryana Cruz, Edgardo Falcón, Mari Carmen Iturbe, Mariela Hernández Cajigas, Carmen S Maldonado-Vlaa. Intra-accumbens shell injections of SR48692 enhanced cocaine self-administration intake in rats exposed to an environmentally-elicited reinstatement paradigm. Brain research. vol 1280. 2009-09-14. PMID:19442653. |
particularly, a significant increase of nt levels was observed within the nucleus accumbens (nac) shell subregion during the acquisition phase of training. |
2009-09-14 |
2023-08-12 |
rat |
| V L Hedges, S Chakravarty, E J Nestler, R L Meise. Delta FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters. Genes, brain, and behavior. vol 8. issue 4. 2009-09-11. PMID:19566711. |
repeated activation of the mesolimbic dopamine system results in persistent behavioral alterations accompanied by a pattern of neural plasticity in the nucleus accumbens (nac). |
2009-09-11 |
2023-08-12 |
Not clear |
| Manuel Mameli, Briac Halbout, Cyril Creton, David Engblom, Jan Rodriguez Parkitna, Rainer Spanagel, Christian Lüsche. Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc. Nature neuroscience. vol 12. issue 8. 2009-09-09. PMID:19597494. |
in the ventral tegmental area (vta), a single exposure to cocaine efficiently triggers nmda receptor-dependent synaptic plasticity in da neurons, whereas plasticity in the nucleus accumbens (nac) occurs only after repeated injections. |
2009-09-09 |
2023-08-12 |
mouse |
| H Franke, C Sauer, C Rudolph, U Krügel, J G Hengstler, P Ille. P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo. Glia. vol 57. issue 10. 2009-09-02. PMID:19115395. |
therefore, the aim of the present study was to identify the role of the phosphoinositide 3 kinase (pi3-k/akt) and the mitogen-activated protein kinase/extracellular signal regulated protein kinase (mapk/erk) pathways in p2y receptor-mediated astrogliosis after traumatic injury and after microinfusion of adp beta s (p2y(1,12,13) receptor agonist) into the rat nucleus accumbens (nac). |
2009-09-02 |
2023-08-12 |
rat |
| Darlene H Brunzell, Yann S Mineur, Rachael L Neve, Marina R Picciott. Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19212318. |
previous studies have implicated nucleus accumbens (nac) creb activity in the modulation of cocaine and morphine reward, and have shown that nicotine conditioned place preference (cpp) is associated with nac creb activation. |
2009-09-02 |
2023-08-12 |
mouse |
| Desirae M Haluk, Stan B Floresc. Ventral striatal dopamine modulation of different forms of behavioral flexibility. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19262467. |
the present study assessed the involvement of da receptors in the nucleus accumbens (nac) core on either between- or within-strategy shifts using operant chamber-based tasks. |
2009-09-02 |
2023-08-12 |
rat |
| Diana Simmons, David W Sel. Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 8. 2009-09-02. PMID:19279569. |
earlier studies suggest that opioid receptors in the ventral tegmental area, but not the nucleus accumbens (nac), play a role in relapse to drug-seeking behavior. |
2009-09-02 |
2023-08-12 |
rat |
| Lucía Hipólito, María José Sánchez-Catalán, Luis Granero, Ana Polach. Local salsolinol modulates dopamine extracellular levels from rat nucleus accumbens: shell/core differences. Neurochemistry international. vol 55. issue 4. 2009-09-02. PMID:19524107. |
to gain an insight into this topic, male wistar rats were stereotaxically implanted with one concentric microdialysis probe in either the shell or the core of the nucleus accumbens (nac). |
2009-09-02 |
2023-08-12 |
human |
| J Weiner, W Lun Sun, L Zhou, C M Kreiter, S Jenab, V Quiñones-Jena. PKA-mediated responses in females' estrous cycle affect cocaine-induced responses in dopamine-mediated intracellular cascades. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19348873. |
the nucleus accumbens (nac) and caudate putamen (cpu) were dissected and analyzed via western blot for total and phosphorylated (p-thr34) dopamine- and 3'-5'-cyclic amp-regulated phosphoprotein with molecular weight 32 kda (darpp-32), pp1, pp2b (cna1 and cnb1 subunits), pka, creb, cfos, and delta-fosb. |
2009-08-24 |
2023-08-12 |
rat |
| Amy C Boudreau, Carrie R Ferrario, Marc J Glucksman, Marina E Wol. Signaling pathway adaptations and novel protein kinase A substrates related to behavioral sensitization to cocaine. Journal of neurochemistry. vol 110. issue 1. 2009-08-21. PMID:19457111. |
cocaine-sensitized rats exhibit increased ampa receptor (ampar) surface expression in the nucleus accumbens (nac) which may in turn enhance drug seeking. |
2009-08-21 |
2023-08-12 |
rat |
| Makoto Ito, Kenji Doy. Validation of decision-making models and analysis of decision variables in the rat basal ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 31. 2009-08-21. PMID:19657038. |
we compared different behavioral learning algorithms to predict the choice sequences generated by rats during a free-choice task and analyzed associated neural activity in the nucleus accumbens (nac) and ventral pallidum (vp). |
2009-08-21 |
2023-08-12 |
rat |
| K J Jackson, C L Walters, M I Dama. Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo. The Journal of pharmacology and experimental therapeutics. vol 330. issue 2. 2009-08-19. PMID:19435931. |
we first show that administration of nicotine increases camkii activity in the ventral tegmental area (vta), nucleus accumbens (nac), and amygdala. |
2009-08-19 |
2023-08-12 |
mouse |