| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jérémie Neasta, Sami Ben Hamida, Quinn Yowell, Sebastien Carnicella, Dorit Ro. Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 46. 2010-12-21. PMID:21041654. |
here we show that administration of alcohol and excessive voluntary consumption of alcohol induce the activation of the mtorc1-mediated signaling pathway in the nucleus accumbens (nac) of rodents. |
2010-12-21 |
2023-08-12 |
Not clear |
| Lixin Li, Xuebing Wang, Long-Chuan Y. Involvement of opioid receptors in the CGRP-induced antinociception in the nucleus accumbens of rats. Brain research. vol 1353. 2010-12-20. PMID:20659434. |
it has been demonstrated that calcitonin gene-related peptide (cgrp) plays important roles in the modulation of nociception in the nucleus accumbens (nac) of rats. |
2010-12-20 |
2023-08-12 |
rat |
| Shuntaro Kohnomi, Katsuya Suemaru, Mitsunori Goda, Tominari Choshi, Satoshi Hibino, Hiromu Kawasaki, Hiroaki Arak. Ameliorating effects of tropisetron on dopaminergic disruption of prepulse inhibition via the alpha(7) nicotinic acetylcholine receptor in Wistar rats. Brain research. vol 1353. 2010-12-20. PMID:20673759. |
next, to find the action site of tropisetron, we examined c-fos protein expression in the nucleus accumbens (nac), dorsolateral striatum (dlst) and ventral tegmental area (vta). |
2010-12-20 |
2023-08-12 |
rat |
| J L Jones, J J Day, R A Wheeler, R M Carell. The basolateral amygdala differentially regulates conditioned neural responses within the nucleus accumbens core and shell. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20570714. |
given the importance of the nucleus accumbens (nac) and the basolateral amygdala (bla) in associative reward processes, recent research has examined the functional importance of bla-nac interactions. |
2010-12-16 |
2023-08-12 |
Not clear |
| Michel C Van den Oever, Bart R Lubbers, Natalia A Goriounova, Ka W Li, Roel C Van der Schors, Maarten Loos, Danai Riga, Joost Wiskerke, Rob Binnekade, M Stegeman, Anton N M Schoffelmeer, Huibert D Mansvelder, August B Smit, Taco J De Vries, Sabine Spijke. Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 10. 2010-12-06. PMID:20592718. |
after extinction of heroin self-administration, downregulation of ecm proteins was also present in the mpfc, as well as nucleus accumbens (nac), and these adaptations were partially restored following cue-induced reinstatement of heroin seeking. |
2010-12-06 |
2023-08-12 |
rat |
| Atsushi Sato, Osamu Nakagawasai, Koichi Tan-No, Hiroshi Onogi, Fukie Niijima, Takeshi Tadan. Influence of olfactory bulbectomy on maternal behavior and dopaminergic function in nucleus accumbens in mice. Behavioural brain research. vol 215. issue 1. 2010-12-06. PMID:20638419. |
furthermore, we measured tyrosine hydroxylase (th) levels using microphotometry and quantified dopamine d1- and d2-like receptors using autoradiography in the nucleus accumbens (nac). |
2010-12-06 |
2023-08-12 |
mouse |
| Nii A Addy, David P Daberkow, Jeremy N Ford, Paul A Garris, R Mark Wightma. Sensitization of rapid dopamine signaling in the nucleus accumbens core and shell after repeated cocaine in rats. Journal of neurophysiology. vol 104. issue 2. 2010-12-01. PMID:20554845. |
to study dopamine neurotransmission after 1-day withdrawal, we used fast-scan cyclic voltammetry (fscv) to determine whether repeated cocaine alters rapid dopamine release and uptake in the nucleus accumbens (nac) core and shell. |
2010-12-01 |
2023-08-12 |
human |
| Ian Maze, Scott J Russ. Transcriptional mechanisms: underlying addiction-related structural plasticity. Molecular interventions. vol 10. issue 4. 2010-11-30. PMID:20729488. |
drug addiction is marked by long-lasting changes in behavior that result, in part, from altered patterns of gene expression within limbic forebrain regions, such as the nucleus accumbens (nac). |
2010-11-30 |
2023-08-12 |
Not clear |
| Jun Wang, Sebastien Carnicella, Somayeh Ahmadiantehrani, Dao-Yao He, Segev Barak, Viktor Kharazia, Sami Ben Hamida, Agustin Zapata, Toni S Shippenberg, Dorit Ro. Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 43. 2010-11-30. PMID:20980608. |
spontaneous firing of ventral tegmental area (vta) dopamine (da) neurons provides ambient levels of da in target areas such as the nucleus accumbens (nac) and the prefrontal cortex (pfc). |
2010-11-30 |
2023-08-12 |
Not clear |
| Vincent Vialou, Ian Maze, William Renthal, Quincey C LaPlant, Emily L Watts, Ezekiell Mouzon, Subroto Ghose, Carol A Tamminga, Eric J Nestle. Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 43. 2010-11-30. PMID:20980616. |
one molecule implicated in such adaptations is Δfosb, a transcription factor that accumulates in the rodent nucleus accumbens (nac), a key brain reward region, in response to either chronic stress or repeated exposure to drugs of abuse. |
2010-11-30 |
2023-08-12 |
mouse |
| N Salmaso, J Hicks, B Woodsid. Effects of parturition on immediate early gene protein expression within the brains of female rats. Neuroscience. vol 169. issue 2. 2010-11-23. PMID:20639131. |
the average number of fos and egr-1-ir cells/section were calculated for the parietal cortex (parcx), nucleus accumbens (nac), medial amygdala (mea), medial preoptic area (mpoa), supraoptic area (son) and cg2. |
2010-11-23 |
2023-08-12 |
rat |
| H C Brenhouse, K Dumais, S L Anderse. Enhancing the salience of dullness: behavioral and pharmacological strategies to facilitate extinction of drug-cue associations in adolescent rats. Neuroscience. vol 169. issue 2. 2010-11-23. PMID:20639130. |
drug-paired associations are largely controlled by the prelimbic prefrontal cortex (plpfc) and its influence on the nucleus accumbens (nac). |
2010-11-23 |
2023-08-12 |
human |
| Jeremy J Day, Joshua L Jones, R Mark Wightman, Regina M Carell. Phasic nucleus accumbens dopamine release encodes effort- and delay-related costs. Biological psychiatry. vol 68. issue 3. 2010-11-22. PMID:20452572. |
dopamine transmission within the nucleus accumbens (nac) has been heavily implicated in reward-learning and decision-making, but it is unclear how dopamine release might contribute to decisions that involve costs. |
2010-11-22 |
2023-08-12 |
Not clear |
| Payam Piray, Mohammad Mahdi Keramati, Amir Dezfouli, Caro Lucas, Azarakhsh Mokr. Individual differences in nucleus accumbens dopamine receptors predict development of addiction-like behavior: a computational approach. Neural computation. vol 22. issue 9. 2010-11-22. PMID:20569176. |
increasing evidence supports the hypothesis that dopamine receptor availability in the nucleus accumbens (nac) predisposes drug reinforcement. |
2010-11-22 |
2023-08-12 |
Not clear |
| David N Linsenbardt, Stephen L Boeh. Ethanol-induced locomotor sensitization in DBA/2J mice is associated with alterations in GABA(A) subunit gene expression and behavioral sensitivity to GABA(A) acting drugs. Pharmacology, biochemistry, and behavior. vol 95. issue 3. 2010-11-01. PMID:20219525. |
sensitized animals displayed increased expression of the alpha1, beta2, and gamma2 (v1) subunits in the nucleus accumbens (nac) but not ventral tegmental area (vta). |
2010-11-01 |
2023-08-12 |
mouse |
| Adam Podet, Min J Lee, Alan C Swann, Nachum Dafn. Nucleus accumbens lesions modulate the effects of methylphenidate. Brain research bulletin. vol 82. issue 5-6. 2010-11-01. PMID:20470871. |
in studies on cocaine and amphetamine, this effect has been reported to involve the nucleus accumbens (nac), one of the nuclei belonging to the motive circuit. |
2010-11-01 |
2023-08-12 |
rat |
| Erin B Larson, Fatih Akkentli, Scott Edwards, Danielle L Graham, Diana L Simmons, Imran N Alibhai, Eric J Nestler, David W Sel. Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal. Journal of neurochemistry. vol 115. issue 1. 2010-10-13. PMID:20633205. |
we found that cfos, fosb, and Δfosb exhibit regionally and temporally distinct expression patterns, with greater accumulation of Δfosb protein in the nucleus accumbens (nac) shell and core after chronic cocaine administration, whereas Δfosb increases in the caudate-putamen (cpu) remained similar with either acute or chronic administration. |
2010-10-13 |
2023-08-12 |
rat |
| Xi Wang, Yi-xiao Luo, Ying-ying He, Fang-qiong Li, Hai-shui Shi, Li-fen Xue, Yan-xue Xue, Lin L. Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 38. 2010-10-08. PMID:20861369. |
we found that exposure to a cocaine-related cue induced reinstatement to cocaine seeking and increased phosphorylation of p70s6 kinase (p70s6k) and ribosomal protein s6 (rps6), measures of mtor activity, in the nucleus accumbens (nac) core but not shell. |
2010-10-08 |
2023-08-12 |
rat |
| Maura L Perry, Gina M Leinninger, Rong Chen, Kathryn D Luderman, Hongyan Yang, Margaret E Gnegy, Martin G Myers, Robert T Kenned. Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. Journal of neurochemistry. vol 114. issue 3. 2010-10-06. PMID:20412389. |
we show that 4 h of systemic leptin treatment enhances amph-stimulated da efflux in the nucleus accumbens (nac) of sprague-dawley rats. |
2010-10-06 |
2023-08-12 |
rat |
| Jie V Deng, Ramona M Rodriguiz, Ashley N Hutchinson, Il-Hwan Kim, William C Wetsel, Anne E Wes. MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants. Nature neuroscience. vol 13. issue 9. 2010-10-04. PMID:20711186. |
here we show that acute viral manipulation of mecp2 expression in the nucleus accumbens (nac) bidirectionally modulates amphetamine (amph)-induced conditioned place preference. |
2010-10-04 |
2023-08-12 |
mouse |