All Relations between nac and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Quincey LaPlant, Vincent Vialou, Herbert E Covington, Dani Dumitriu, Jian Feng, Brandon L Warren, Ian Maze, David M Dietz, Emily L Watts, Sergio D Iñiguez, Ja Wook Koo, Ezekiell Mouzon, William Renthal, Fiona Hollis, Hui Wang, Michele A Noonan, Yanhua Ren, Amelia J Eisch, Carlos A Bolaños, Mohamed Kabbaj, Guanghua Xiao, Rachael L Neve, Yasmin L Hurd, Ronald S Oosting, Gouping Fan, John H Morrison, Eric J Nestle. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nature neuroscience. vol 13. issue 9. 2010-10-04. PMID:20729844. we found that dnmt3a expression was regulated in mouse nucleus accumbens (nac) by chronic cocaine use and chronic social defeat stress. 2010-10-04 2023-08-12 mouse
Thibaut Sesia, Vincent Bulthuis, Sonny Tan, Lee Wei Lim, Rinske Vlamings, Arjan Blokland, Harry W M Steinbusch, Trevor Sharp, Veerle Visser-Vandewalle, Yasin Teme. Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin. Experimental neurology. vol 225. issue 2. 2010-10-01. PMID:20615406. the nucleus accumbens (nac) is gaining interest as a target for deep brain stimulation (dbs) in refractory neuropsychiatric disorders with impulsivity as core symptom. 2010-10-01 2023-08-12 human
Xia Li, Jie Li, Eliot L Gardner, Zheng-Xiong X. Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats. Journal of neurochemistry. vol 114. issue 5. 2010-09-13. PMID:20534005. intracranial microinjections of amn082 into the nucleus accumbens (nac) or ventral pallidum, but not the dorsal striatum, also inhibited cocaine-primed reinstatement, an effect that was blocked by local co-administration of mmpip, a selective mglur7 antagonist. 2010-09-13 2023-08-12 rat
Darlene H Brunzell, Karen E Boschen, Elizabeth S Hendrick, Patrick M Beardsley, J Michael McIntos. Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 3. 2010-09-07. PMID:19890263. using local infusion of alpha-conotoxin mii (alpha-ctx mii), an antagonist with selectivity for alpha6beta2(*)nachrs, the purpose of these experiments was to determine if alpha6beta2(*)nachrs in the nucleus accumbens (nac) shell are required for motivation to self-administer nicotine. 2010-09-07 2023-08-12 rat
Carrie R Ferrario, Xuan Li, Xiaoting Wang, Jeremy M Reimers, Jamie L Uejima, Marina E Wol. The role of glutamate receptor redistribution in locomotor sensitization to cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 3. 2010-09-07. PMID:19924109. alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor (ampar) surface expression in the nucleus accumbens (nac) is enhanced after withdrawal from repeated cocaine exposure. 2010-09-07 2023-08-12 rat
Nadia Chaudhri, Lacey L Sahuque, William W Schairer, Patricia H Jana. Separable roles of the nucleus accumbens core and shell in context- and cue-induced alcohol-seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 3. 2010-09-07. PMID:19924113. we tested the hypothesis that differential recruitment of the nucleus accumbens (nac) core and shell mediates responding to drug cues in a drug vs non-drug context. 2010-09-07 2023-08-12 rat
Cristina Núñez, Fátima Martín, Anna Földes, M Luisa Laorden, Krisztina J Kovács, M Victoria Milané. Induction of FosB/DeltaFosB in the brain stress system-related structures during morphine dependence and withdrawal. Journal of neurochemistry. vol 114. issue 2. 2010-08-23. PMID:20438612. the transcription factor deltafosb is induced in the nucleus accumbens (nac) by drugs of abuse. 2010-08-23 2023-08-12 rat
Z Ren, W L Sun, H Jiao, D Zhang, H Kong, X Wang, M X. Dopamine D1 and N-methyl-D-aspartate receptors and extracellular signal-regulated kinase mediate neuronal morphological changes induced by repeated cocaine administration. Neuroscience. vol 168. issue 1. 2010-08-20. PMID:20346392. changes in dendritic morphology in medium spiny neurons (msns) in the nucleus accumbens (nac) and caudate putamen (cpu) accompany drug-induced enduring behavioral and molecular changes. 2010-08-20 2023-08-12 Not clear
R L Saint Marie, E J Miller, M R Breier, M Weber, N R Swerdlo. Projections from ventral hippocampus to medial prefrontal cortex but not nucleus accumbens remain functional after fornix lesions in rats. Neuroscience. vol 168. issue 2. 2010-08-19. PMID:20338222. to determine whether these nonfornical pathways might mediate forebrain activation after vh nmda infusion, we examined the effects of bilateral vh nmda infusion on c-fos protein expression in the mpfc and nucleus accumbens (nac) after sham vs. bilateral fornix lesions. 2010-08-19 2023-08-12 human
Michael J McCarthy, Hailing Zhang, Norton H Neff, Maria Hadjiconstantino. Nicotine withdrawal and kappa-opioid receptors. Psychopharmacology. vol 210. issue 2. 2010-08-17. PMID:19806344. the synthesis and release of dynorphin are increased in the caudate/putamen (cpu) and nucleus accumbens (nac) of nicotine-withdrawn mice, suggesting a role in the nicotine abstinence syndrome. 2010-08-17 2023-08-12 mouse
Stephanie R Ebner, Mitchell F Roitman, David N Potter, Anna B Rachlin, Elena H Chartof. Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens. Psychopharmacology. vol 210. issue 2. 2010-08-17. PMID:20372879. although kor agonists decrease dopamine in the nucleus accumbens (nac), kor modulation of phasic dopamine release in the core and shell subregions of the nac-which have distinct roles in reward processing-remains poorly understood. 2010-08-17 2023-08-12 Not clear
Peipei Chau, Helga Höifödt-Lidö, Elin Löf, Bo Söderpalm, Mia Ericso. Glycine receptors in the nucleus accumbens involved in the ethanol intake-reducing effect of acamprosate. Alcoholism, clinical and experimental research. vol 34. issue 1. 2010-08-10. PMID:19860809. we have previously demonstrated that strychnine-sensitive glycine receptors (glyrs) in the nucleus accumbens (nac) and nicotinic acetylcholine receptors (nachrs) in the ventral tegmental area are involved in mediating ethanol (etoh)-induced elevation of dopamine in the rat mesolimbic dopamine system. 2010-08-10 2023-08-12 rat
Peipei Chau, Rosita Stomberg, Anne Fagerberg, Bo Söderpalm, Mia Ericso. Glycine receptors involved in acamprosate's modulation of accumbal dopamine levels: an in vivo microdialysis study. Alcoholism, clinical and experimental research. vol 34. issue 1. 2010-08-10. PMID:19860810. glycine receptors (glyrs) in the nucleus accumbens (nac) and nicotinic acetylcholine receptors (nachrs) in the ventral tegmental area (vta) have been suggested to be involved in the positive reinforcing and dopamine elevating effects of ethanol. 2010-08-10 2023-08-12 rat
Milena Moretti, Manolo Mugnaini, Michela Tessari, Michele Zoli, Annalisa Gaimarri, Irene Manfredi, Francesco Pistillo, Francesco Clementi, Cecilia Gott. A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes. Molecular pharmacology. vol 78. issue 2. 2010-08-03. PMID:20439469. in the mp group, alpha4beta2 nachrs were up-regulated in all brain regions, alpha6beta2* nachrs were down-regulated in the nucleus accumbens (nac) and caudate-putamen, and alpha7 nachrs were up-regulated in the caudal cerebral cortex (ccx); the up-regulation of alpha4beta2alpha5 nachrs in the ccx was also suggested. 2010-08-03 2023-08-12 rat
Mia Ericson, Rhona B C Clarke, PeiPei Chau, Louise Adermark, Bo Söderpal. beta-Alanine elevates dopamine levels in the rat nucleus accumbens: antagonism by strychnine. Amino acids. vol 38. issue 4. 2010-07-30. PMID:19543795. glycine receptors (glyrs) in the nucleus accumbens (nac) have recently been suggested to be involved in the reinforcing and dopamine-elevating properties of ethanol via a neuronal circuitry involving the vta. 2010-07-30 2023-08-12 rat
Nesrin Filiz Basaran, R Levent Buyukuysal, William R Millington, Sinan Cavu. Glycyl-glutamine (beta-endorphin(30-31)) inhibits morphine-induced dopamine efflux in the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 381. issue 5. 2010-07-23. PMID:20349045. in this study, we tested the hypothesis that gly-gln inhibits morphine reward by blocking morphine-induced dopamine efflux in the nucleus accumbens (nac). 2010-07-23 2023-08-12 rat
Kristy R Crooks, Daniel T Kleven, Ramona M Rodriguiz, William C Wetsel, James O McNamar. TrkB signaling is required for behavioral sensitization and conditioned place preference induced by a single injection of cocaine. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20176040. we assessed also activation of endogenous trkb by quantifying levels of phosphorylated trkb (p-trkb) in the nucleus accumbens (nac). 2010-07-19 2023-08-12 mouse
Garret D Stuber, Thomas S Hnasko, Jonathan P Britt, Robert H Edwards, Antonello Bonc. Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 24. 2010-07-02. PMID:20554874. here, we expressed the light-activated cation channel channelrhodopsin-2 (chr2) in genetically defined midbrain dopamine neurons to stimulate exocytosis specifically from dopaminergic terminals in both the nucleus accumbens (nac) shell and dorsal striatum of brain slices from adult mice. 2010-07-02 2023-08-12 mouse
Frédéric Lallemand, Roberta J Ward, Philippe De Witt. The influence of chronic nicotine administration on behavioural and neurochemical parameters in male and female rats after repeated binge drinking exposure. Alcohol and alcoholism (Oxford, Oxfordshire). vol 44. issue 6. 2010-06-30. PMID:19737814. the possible interaction between nicotine and 'binge drinking' in eliciting changes in behavioural patterns of 'binge drinking' rats as well as nucleus accumbens (nac) glutamate levels has been investigated in these present studies. 2010-06-30 2023-08-12 rat
Anna Castañé, David E H Theobald, Trevor W Robbin. Selective lesions of the dorsomedial striatum impair serial spatial reversal learning in rats. Behavioural brain research. vol 210. issue 1. 2010-06-30. PMID:20153781. this study directly evaluated the contribution of core and shell sub-regions of the nucleus accumbens (nac), dorsomedial (dms) and dorsolateral (dls) striatum to reversal learning of an instrumental two-lever spatial discrimination task in rats. 2010-06-30 2023-08-12 rat